
Benzimidazole and Imidazole Derivatives
Benzimidazole is a compound consisting of a benzene ring fused to an imidazole ring, a five-membered structure containing two nitrogen atoms. Benzimidazole derivatives, such as albendazole, are known for their antiparasitic and antifungal activity, used in the treatment of parasitic infections and certain parasitic diseases in animals and humans. Imidazole, on the other hand, is a five-membered structure with two nitrogen atoms found in various biologically active compounds. Imidazole derivatives, such as metronidazole, have antimicrobial and antiparasitic properties. These compounds are also used in the pharmaceutical industry for treating bacterial infections, parasitic diseases, and some fungal infections, as well as in organic chemistry as catalysts.
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Found 10376 products of "Benzimidazole and Imidazole Derivatives"
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Solifenacin EP impurity F succinate
CAS:<p>Solifenacin is an anti-cholinergic drug that has been shown to have a potent antagonistic effect on muscarinic receptors. It is used in the treatment of overactive bladder, urinary incontinence, and irritable bowel syndrome. Solifenacin succinate is a metabolite of solifenacin and it has been found to be an antagonist of M3 muscarinic receptors. The presence of solifenacin and its metabolites in wastewater can interfere with treatment processes by inhibiting the removal of other organic chemicals such as tamsulosin hydrochloride. Optimisation studies for solifenacin production have shown that famotidine can be used as a process aid to reduce solifenacin impurities. Famotidine is also an antagonist of M3 muscarinic receptors and can be used to remove solifenacin from wastewater. Analytes detected in wastewater samples include solifenacin, famot</p>Formula:C27H32N2O6Purity:Min. 95%Molecular weight:480.55 g/molDesdifluoromethoxy hydroxy pantoprazole
CAS:<p>Desdifluoromethoxy hydroxy pantoprazole is a synthetic compound that is used as an impurity standard for the drug product Pantoprazole. It has a purity of ≥98% and is stable under ambient conditions. Desdifluoromethoxy hydroxy pantoprazole is not active on its own, but it is a metabolite of pantoprazole. It can be used to study the metabolism of pantoprazole.</p>Formula:C15H15N3O4SPurity:Min. 95%Molecular weight:333.36 g/molScopine-2,2-dithienyl glycolate
CAS:<p>Scopine-2,2-dithienyl glycolate is a catalyst that belongs to the class of dithienyl glycolates. Scopine-2,2-dithienyl glycolate is used in the pharmaceutical industry as an average catalyst for reactions and can be used to recover dimethylbenzene. The method of detection for scopine-2,2-dithienyl glycolate is based on its ability to absorb light at a wavelength of 360 nm. The reaction solution must be monitored carefully during the synthetic process because it has been shown that it can react with water or air and form hydrogen sulfide gas. If this happens, the reaction solution will become cloudy or turbid. This product is a white crystalline solid that appears as tiny needles and has a melting point of 173 degrees Celsius (340 degrees Fahrenheit).</p>Formula:C18H19NO4S2Purity:Min. 95%Molecular weight:377.48 g/molCarbamazepine impurity
CAS:<p>Carbamazepine is a drug that has been used to treat epileptic seizures and trigeminal neuralgia. Impurities in the drug are removed by using chromatographic methods, such as high-performance liquid chromatography (HPLC). The rotarod test is an animal model of motor coordination and balance that can be used to assess the effects of drugs on these functions. Carbamazepine impurities may cause depression and have an epileptic effect on animals. Chronic exposure to carbamazepine can lead to drug reactions and gene polymorphisms, which may alter the metabolism of the drug. Analytical methods for determining carbamazepine impurities include HPLC, gas chromatography mass spectrometry (GC-MS), and thin-layer chromatography (TLC).</p>Formula:C15H14N2OPurity:Min. 95%Molecular weight:238.28 g/molDehydrodeoxy donepezil
CAS:<p>Dehydrodeoxy donepezil is an analytical standard that is used in the manufacture of pharmaceuticals. It is a synthetic drug impurity, and its CAS number is 120013-45-8. Dehydrodeoxy donepezil can be found in the API impurity grade of various drugs, including those that are manufactured by Custom synthesis and natural synthesis. The pharmacopoeia states that dehydrodeoxy donepezil has a purity level of 98% or greater. This product can also be found as a metabolite in humans, with its half-life being approximately 40 minutes.</p>Formula:C24H29NO2Purity:Min. 95%Molecular weight:363.49 g/mol2-Hydroxy-5-methyl-γ-phenylbenzenepropanol
CAS:<p>2-Hydroxy-5-methylphenylbenzenepropanol is an aliphatic phenol that is used as a treatment for benzene poisoning. It is also used as a precursor to other compounds, such as the chlorides and alkylates of 2-hydroxy-5-methylphenylbenzenepropanol. This compound can be synthesized by reacting ethyl benzoylacetate with diisopropylamine in the presence of oxygen and chlorine gas. It is often immobilized using nutrients, l-tartaric acid, or cinnamic acid.</p>Formula:C16H18O2Purity:Min. 95%Molecular weight:242.31 g/molLansoprazole impurity H
CAS:<p>Lansoprazole impurity H is a metabolite of lansoprazole, a proton pump inhibitor that inhibits the production of stomach acid. Lansoprazole impurity H is used in research and development as an analytical standard to measure lansoprazole concentrations in drug products. It is also used as an impurity standard for pharmacopoeia purposes. Lansoprazole impurity H is not known to be toxic, but it has not been evaluated for carcinogenicity or reproductive toxicity.</p>Formula:C23H16F3N5OSPurity:90%MinMolecular weight:467.47 g/molTiotropium Bromide EP Impurity G
CAS:<p>Tiotropium Bromide EP Impurity G is an anticholinergic bronchodilator that is used in the treatment of asthma. Tiotropium Bromide EP Impurity G has been shown to have long-acting properties, with a half-life of about 20 hours. It has a high affinity for the muscarinic receptor and acts as a competitive antagonist at this site. Tiotropium Bromide EP Impurity G also has a cavity, which may be necessary for its activity.</p>Formula:C9H6BrNO2Purity:Min. 95%Molecular weight:240.05 g/mol2-Methoxy-5-methyl-γ-phenylbenzenepropanol
CAS:<p>2-Methoxy-5-methyl-gamma-phenylbenzenepropanol is a synthetic compound that is used as an intermediate in the synthesis of coumarin derivatives. Reaction with sulfonating agents produces sulfones, and reaction with borohydride reagents produces boronates. The synthesis of 2-methoxy-5-methyl-gamma-phenylbenzenepropanol can be accomplished by the reduction of diphenyl ethers with lithium aluminum hydride or borohydride. The reduction can also be carried out using lanthanum oxide and potassium borohydride. The reaction proceeds smoothly at room temperature in nonpolar solvents.<br>2-Methoxy-5-methyl-gamma-phenylbenzenepropanol reacts with chloride to produce the corresponding chlorides, which are useful intermediates for the synthesis of tolterodine tartrate, a drug used to treat urinary inc</p>Formula:C17H20O2Purity:Min. 95%Molecular weight:256.34 g/molN-Methyl omeprazole (Mixture of isomers with the methylated nitrogens of imidazole)
<p>Please enquire for more information about N-Methyl omeprazole (Mixture of isomers with the methylated nitrogens of imidazole) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formula:C18H21N3O3SPurity:Min. 95%Molecular weight:359.44 g/molAlbendazole impurity F
CAS:<p>Albendazole is an anti-helminthic drug that is structurally classified as a benzimidazole. It has been shown to be effective against a variety of helminths, including roundworms, pinworms, hookworms, and tapeworms. Albendazole impurity F is an analytical standard for the determination of albendazole in pharmaceutical products by HPLC. It also serves as a reference substance to establish the purity of drug products containing albendazole and its metabolites. Albendazole impurity F is not considered to be a metabolite of albendazole because it has been shown to be stable under acidic conditions and can be synthesized from other starting materials.</p>Formula:C10H11N3O2SPurity:Min. 95%Molecular weight:237.28 g/mol4-Methyl-2-[3-[(1-methylethyl)amino]-1-phenylpropyl]phenol
CAS:<p>4-Methyl-2-[3-[(1-methylethyl)amino]-1-phenylpropyl]phenol is a synthetic impurity standard that is used in the synthesis of drug products. This compound is also known as 4-methyl-2-[3-[(1-methylethyl)amino]-1-phenylpropyl]phenol and has a CAS number of 480432-14-2. It is used to verify the purity of drugs and drug products. 4MMPP can be found in pharmacopoeia, drug development, and metabolite studies. This compound is a research and development product for niche markets. 4MMPP can be obtained through custom synthesis or by synthesis.</p>Formula:C19H25NOPurity:Min. 95%Molecular weight:283.41 g/molAmino albendazole
CAS:<p>Albendazole is a sulfoxide anthelmintic drug that is used to treat worm infections in livestock and pets. Albendazole inhibits the synthesis of the parasitic cell membrane, which disrupts the integrity of the cell and leads to death. The analytical method for measuring albendazole includes extraction with hexane followed by analysis using gas chromatography. In humans, albendazole may be used to treat cancer, especially when it occurs in cavities or fatty tissues. It can also be used as a treatment for certain types of parasitic infections, such as toxoplasmosis, amebiasis, and cysticercosis. Albendazole is absorbed well after oral administration and plasma concentrations are proportional to dosage levels. The most common side effects are nausea and headache.</p>Formula:C10H13N3SPurity:Min. 95%Molecular weight:207.3 g/mol1-Phenyl-1,2,3,4-tetrahydro-isoquinoline
CAS:<p>1-Phenyl-1,2,3,4-tetrahydro-isoquinoline is a synthetic compound which has been used as a lead compound for the development of drugs with dopamine β-hydroxylase inhibitory activity. In vitro studies have shown that 1-phenyl-1,2,3,4-tetrahydro-isoquinoline inhibits human serum dopamine β-hydroxylase and can be used to study the possible role of this enzyme in Parkinson's disease. This drug is racemized in the body and has been found to be effective against Parkinson's disease in rats. It is also an enantiomer that has industrial applications for the production of polyurethane foam insulation coatings.</p>Formula:C15H15NPurity:Min. 95%Color and Shape:PowderMolecular weight:209.29 g/mol(R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline
CAS:<p>(R)-1-Phenyl-1,2,3,4-tetrahydroisoquinoline is a chiral molecule with four stereocenters. It is synthesized by the reaction of sulfamic acid and cyclohexene in the presence of p-toluenesulfonic acid. The product formed is then dehydrogenated to produce (R)-1-phenyl-1,2,3,4-tetrahydroisoquinoline. This compound is soluble in organic solvents such as benzene and ethane and can be used as an acceptor for chiral stationary phases.</p>Formula:C15H15NPurity:Min. 95%Color and Shape:PowderMolecular weight:209.29 g/molPregabalin impurity PD 0312236 and Pregabalin impurity PD 0312237 (mixture of tautomeric isomers)
CAS:<p>Lactose conjugate degradation product of pregabalin</p>Formula:C20H35NO11Purity:Min. 95%Molecular weight:465.49 g/mol1-[[4-(3-Methoxypropoxy)-3-methyl-2-pyridinyl]methyl]-2-[[[4-(3-methoxypropoxy)-3-methyl-2-pyridinyl]methyl]thio]-1H-benzimidazole
CAS:<p>1-[[4-(3-Methoxypropoxy)-3-methyl-2-pyridinyl]methyl]-2-[[[4-(3-methoxypropoxy)-3-methyl-2-pyridinyl]methyl]thio]-1H-benzimidazole is a drug product with analytical applications. It has been shown to have natural and synthetic origins, as well as impurities of its own. It is a custom synthesis and research and development compound that is used for HPLC standardization. The compound has been synthesized for the purpose of drug development and it is intended for niche use.</p>Formula:C29H36N4O4SPurity:Min. 95%Molecular weight:536.69 g/molOmeprazole Impurity 65
<p>Impurity 65 is an impurity of Omeprazole, a drug used to treat gastroesophageal reflux disease and peptic ulcer. Impurity 65 is a metabolite of Omeprazole that can be found in the drug product at a concentration up to 0.5%. It has been shown to have anti-inflammatory effects and can be used as a research and development standard for HPLC analysis. Impurity 65 is also used as an impurity standard in the USP pharmacopoeia and other pharmacopoeias around the world.</p>Formula:C17H17N3O4Purity:Min. 95%Molecular weight:327.33 g/mol(R,R)-Solifenacin succinate
CAS:<p>(R,R)-Solifenacin succinate is a pharmaceutical agent that acts as an antimuscarinic drug. It has been shown to be effective in wastewater treatment, where it was found to reduce the amount of solifenacin and optimised organic chemicals in the water. This drug has also been shown to have antagonist properties against the muscarinic receptor M3.</p>Formula:C23H26N2O2•C4H6O4Purity:Min. 95%Color and Shape:PowderMolecular weight:480.55 g/mol1-Deoxy-4-O-β-D-galactopyranosyl-1-[(4R)-4-(2-methylpropyl)-2-oxo-1-pyrrolidinyl]-β-D-fructopyranose/furanose
CAS:<p>Lactose conjugate degradation product of pregabalin</p>Formula:C20H35NO11Purity:Min. 95%Color and Shape:PowderMolecular weight:465.49 g/mol
