Purines and Pyrimidine Derivatives
Purines have a bicyclic structure, consisting of a six-membered ring fused to a five-membered ring, both containing nitrogen atoms in key positions. Purine derivatives, such as adenine and guanine, are essential for the formation of DNA and RNA. These compounds have therapeutic applications in cancer and viral disease treatments by inhibiting cell replication. Pyrimidines, on the other hand, have a monocyclic six-membered structure with two nitrogen atoms. Their derivatives, such as cytosine, thymine, and uracil, are also essential components of DNA and RNA and are used in chemotherapy and antiviral treatments.
At CymitQuimica, we offer purine and pyrimidine derivatives for research in molecular biology, genomics, and the development of innovative therapies.
Found 8948 products of "Purines and Pyrimidine Derivatives"
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(R)-9-[2-(Diethylphosphonomethoxy)propyl] Adenine
CAS:Controlled Product<p>Applications A acyclic phosphonate nucleotide.<br></p>Formula:C13H22N5O4PColor and Shape:White SolidMolecular weight:343.32Sumatriptan
CAS:Controlled Product<p>Applications Sumatriptan is a serotonin 5HT1-receptor agonist.<br>References Humphrey, P.P.A., et al.: Brit. J. Pharmacol., 94, 1123 (1988); Doenicke, A., et al.: Lancet 1, 1309 (1988)<br></p>Formula:C14H21N3O2SColor and Shape:White To Light YellowMolecular weight:295.406-Mercaptopurine-13C2,15N (major)
CAS:Controlled Product<p>Applications An immunosuppressive drug used to treat leukemia. It is also used for pediatric non-Hodgkin’s lymphoma, polycythemia vera, and psoriatic arthritis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Naguib, F., et al.: Biochem. Pharmacol., 50, 1685 (1995), Zeng, H., et al.: Biochem. Pharmacol., 68, 911 (2004).<br></p>Formula:C313C2H4N315NSColor and Shape:NeatMolecular weight:155.16Febuxostat-d9
CAS:Controlled Product<p>Applications Labelled Febuxostat (F229000). Xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout.<br>References Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (1993), Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003), Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005), Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005),<br></p>Formula:C16D9H7N2O3SColor and Shape:NeatMolecular weight:325.432-Amino-2′-deoxyadenosine
CAS:Formula:C10H14N6O3Purity:98%Color and Shape:SolidMolecular weight:266.2611,2,3,9-Tetrahydro-4H-carbazol-4-one
CAS:Controlled Product<p>Applications A carbazole derivative with antimycobacterial activity.<br>References Romeo, G., et al.: Bioorg. Med. Chem., 14, 5211 (2006),<br></p>Formula:C12H11NOColor and Shape:BeigeMolecular weight:185.22Istradefylline
CAS:<p>Applications Istradefylline is a selective A(2A) antagonist used in the treatment of Parkinson’s disease.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dungo, R. et al.: Drugs., 73, 875 (2013); Stoessel, A. et al.: J. Med. Chem., 56, 4580 (2013);<br></p>Formula:C20H24N4O4Color and Shape:NeatMolecular weight:384.434-(3-Chlorothiophen-2-yl)-6-methylpyrimidin-2-amine
CAS:Purity:95+%Molecular weight:225.69000244140625Pemetrexed Sodium Methyl Ester
Controlled Product<p>Applications Pemetrexed Sodium Methyl Ester is an impurity of Pemetrexed(P219550). Pemetrexed Disodium Heptahydrate is an chemotherapy drug for the treatment of pleural mesothelioma and non-small cell lung cancer. Pemetrexed Disodium Heptahydrate exhibit inhibitory activities towards thymidylate synthase as well as other folate dependent enzymes.<br>References Vogelzang, N.J., et al.: J. Clin. Oncol., 21,2636 (2003); Paz-Ares, L., et al.: Lancet. Oncol., 13, 247 (2012);<br></p>Formula:C21H22N5NaO6Color and Shape:NeatMolecular weight:463.4194-(furan-2-yl)-6-[4-(propan-2-yl)phenyl]pyrimidin-2-amine
CAS:Purity:95.0%Molecular weight:279.34298706054695-METHOXY-4-((4-(1-METHYL-1H-INDOL-3-YL)PYRIMIDIN-2-YL)AMINO)-2-NITROPHENOL
Purity:95.0%Molecular weight:391.3869934082031Hypoxanthine-13C2,15N (Mixture)
CAS:<p>Applications A metabolite of Purine in cocaine addiction.<br>References Jansen, R., et al.: Clin. Biochem., 38, 362 (2005), Vorst, O., et al.: Metabolomics, 1, 169 (2005), Want, E., et al.: ChemBioChem., 6, 1941 (2005), van der Werf, M., et al.: Anal. Biochem., 370, 17 (2007),<br></p>Formula:C3C2H4N3NOColor and Shape:NeatMolecular weight:139.09Xanthine
CAS:<p>Applications Found in animal organs, yeast, patatoes, coffee beans, tea. This drug can be used to relax and widen certain breathing passages of the lungs. It is also found that a large number of derivatives have adenoside receptor antagonist properties.<br>References Mueller, C. et. al: Handbook Exp. Pharmacol. 200,151(2011)<br></p>Formula:C5H4N4O2Color and Shape:White SolidMolecular weight:152.11Tryptamine
CAS:<p>Applications Tryptamine is a monoamine alkaloid found in plants. Tryptamine is commonly used in the preparation of biologically active compounds such as neurotransmitters and psychedelics.<br>References Nichols, D. E., et al.: Curr. Top. Behav. Neurosci., 36, 1(2018); Espinoza, S., et al.: Top. Med. Chem., 23, 175 (2017)<br></p>Formula:C10H12N2Color and Shape:YellowMolecular weight:160.22N2-Methylpyrimidine-2,5-diamine
CAS:Color and Shape:Solid, Brown solidMolecular weight:124.147003173828123-(2-CHLOROPYRIMIDIN-4-YL)-1-(CYCLOPROPYLSULFONYL)-1H-INDOLE
Purity:95.0%Molecular weight:333.79000854492192-[5-amino-3-(2-furyl)-1H-pyrazol-1-yl]-6-propylpyrimidin-4(3H)-one
CAS:Purity:95.0%Molecular weight:285.3070068359375N6-(2-Isopentenyl)adenine
CAS:Controlled Product<p>Applications N6-(2-Isopentenyl)adenine can be used in biological study for cytokinins stimulated expression of stress-related proteins and transcripts in Arabidopsis thaliana with isopentenyltransferase overexpression.<br>References Skalak, J., et al.: J. Exp. Bot., 67, 2861-2873 (2016)<br></p>Formula:C10H13N5Color and Shape:White To Off-WhiteMolecular weight:203.24
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