
Purines and Pyrimidine Derivatives
Purines have a bicyclic structure, consisting of a six-membered ring fused to a five-membered ring, both containing nitrogen atoms in key positions. Purine derivatives, such as adenine and guanine, are essential for the formation of DNA and RNA. These compounds have therapeutic applications in cancer and viral disease treatments by inhibiting cell replication. Pyrimidines, on the other hand, have a monocyclic six-membered structure with two nitrogen atoms. Their derivatives, such as cytosine, thymine, and uracil, are also essential components of DNA and RNA and are used in chemotherapy and antiviral treatments.
At CymitQuimica, we offer purine and pyrimidine derivatives for research in molecular biology, genomics, and the development of innovative therapies.
Found 8888 products of "Purines and Pyrimidine Derivatives"
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4-(furan-2-yl)-6-(3-methylthiophen-2-yl)pyrimidin-2-amine
CAS:Purity:95.0%Molecular weight:257.30999755859375Methotrexate Triglutamate Trifluoroacetate
CAS:Controlled Product<p>Applications Methotrexate Triglutamate is a metabolite of Methotrexate (M260675); a folic acid antagonist, antineoplastic, and antirheumatic.<br>References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958); Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985)<br></p>Formula:C30H36N10O11xC2HF3O2Color and Shape:NeatMolecular weight:712.672-Methylimidazole
CAS:<p>Applications 2-Methylimidazole is a monomethylated imidazole that can be used as a building block in the preparation of a wide range of biologically active compounds. 2-Methylimidazole as well as other imidazoles can be use as catalyst for refolding of enhanced coloured fluorescent protein. 2-Methylimidazole has been identified as a byproduct of fermentation and is detected in foods and mainstream and side-stream tobacco smoke.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Shi, R. et al.: Arch. Biochem. Biophys., 459, 122 (2007); Chan, P.C. et al.: Arch. Toxicol., 82, 399 (2008); Nishie, K. et al.: Toxicol. Appl. Pharmacol., 14, 301 (1969);<br></p>Formula:C4H6N2Color and Shape:NeatMolecular weight:82.102-Amino-2′-deoxyadenosine
CAS:Formula:C10H14N6O3Purity:98%Color and Shape:SolidMolecular weight:266.261MTIC-d3
CAS:Controlled Product<p>Applications A labelled metabolite of Temozolomide, an antineoplastic.<br></p>Formula:C5H5D3N6OColor and Shape:Off White SolidMolecular weight:171.182-Amino-6-(5-methylfuran-2-yl)-5-nitropyrimidin-4-yl 4-methylbenzenesulfonate
CAS:Purity:97%Molecular weight:390.3699951171875N-{4-[(4,6-Dimethylpyrimidin-2-yl)sulfamoyl]phenyl}-3-methylbenzamide
CAS:Molecular weight:396.4700012207031N-[[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]hydroxyphosphinyl]-D-alanine 1-Methylethyl Ester
CAS:Controlled Product<p>Applications N-[[[(1R)-2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]hydroxyphosphinyl]-D-alanine 1-Methylethyl Ester prorug of PMPA, phenyl monophosphoramidate, and is a Tenofovir (T018500) derivative, an acyclic phosphonate nucleotide analogue; reverse transcriptase inhibitor. Used as an anti-HIV agent. Antiviral.<br>References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997), Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007), Lee, W. et al.: Antimicrob. Agents Chemother., 49, 1898 (2005);<br></p>Formula:C15H25N6O5PPurity:>85%Color and Shape:NeatMolecular weight:400.37Tert-Butyl 2-((4R,6S)-6-((E)-2-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate
CAS:Purity:97%Molecular weight:577.71002197265624-(Benzylamino)-2-((3-chloro-4-hydroxyphenethyl)amino)pyrimidine-5-carboxamide
CAS:Purity:95.0%Molecular weight:397.85998535156254,6-Dichloro-2,5-diphenylpyrimidine
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:301.1700134277344Sumatriptan
CAS:Controlled Product<p>Applications Sumatriptan is a serotonin 5HT1-receptor agonist.<br>References Humphrey, P.P.A., et al.: Brit. J. Pharmacol., 94, 1123 (1988); Doenicke, A., et al.: Lancet 1, 1309 (1988)<br></p>Formula:C14H21N3O2SColor and Shape:White To Light YellowMolecular weight:295.401-(3-Methylbut-2-en-1-yl)guanidine hydrochloride(1:x)
CAS:Purity:97.0%Molecular weight:163.649993896484Acetal
CAS:<p>Stability Volatile<br>Applications Acetal is a flavouring component of Baiju and Rum. It is also a useful reactant in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Franitza, Laura, et al.: J. of Agric. and Food Chem., 64(47), 9041-9053 (2016);<br></p>Formula:C6H14O2Color and Shape:ColourlessMolecular weight:118.17N-(2-CHLORO-5-METHOXYPYRIMIDIN-4-YL)-1H-INDAZOL-6-AMINE
CAS:Purity:95.0%Molecular weight:275.70001220703125N-(2-Hydroxy-6-methylphenyl)-2-((6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-yl)amino)thiazole-5-carboxamide
CAS:Purity:95+%Molecular weight:469.559997558593757-Hydroxy Memantine Hydrochloride
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications A metabolite of Memantine (M218000), used for the treatment of neurological disorders.<br>References Eiichi, K., et al.: Chem. Pharm. Bull., 33, 4680 (1985),<br></p>Formula:C12H21NO·ClHColor and Shape:NeatMolecular weight:231.76

