
Purines and Pyrimidine Derivatives
Purines have a bicyclic structure, consisting of a six-membered ring fused to a five-membered ring, both containing nitrogen atoms in key positions. Purine derivatives, such as adenine and guanine, are essential for the formation of DNA and RNA. These compounds have therapeutic applications in cancer and viral disease treatments by inhibiting cell replication. Pyrimidines, on the other hand, have a monocyclic six-membered structure with two nitrogen atoms. Their derivatives, such as cytosine, thymine, and uracil, are also essential components of DNA and RNA and are used in chemotherapy and antiviral treatments.
At CymitQuimica, we offer purine and pyrimidine derivatives for research in molecular biology, genomics, and the development of innovative therapies.
Found 8902 products of "Purines and Pyrimidine Derivatives"
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1,3-dioxo-2-pyrimidin-2-ylisoindoline-5-carboxylic acid
CAS:Purity:95.0%Molecular weight:269.21600341796875N-Desmethoxypropyl Prucalopride
CAS:Controlled Product<p>Applications N-Desmethoxypropyl Prucalopride is an impurity of Prucalopride (P838950), a selective 5-HT4 receptor agonist used effective for chronic constipation, but is not currently approved in the U.S. Prucalopride is approved for the treatment of chronic constipation in Europe.<br>References Shah, N., et al.: Am. J. Gastroenterol., 103, 1746 (2008), McKinnell, R., et al.: J. Med. Chem., 52, 5330 (2009), Shah, N., et al.: Am. J. Gastroenterol., 103, 1746 (2008),<br></p>Formula:C14H18ClN3O2Color and Shape:NeatMolecular weight:132.201N4-(Benzo[d][1,3]dioxol-5-ylmethyl)-6-(3-methoxyphenyl)pyrimidine-2,4-diamine
CAS:Purity:95.0%Molecular weight:350.37799072265625Ref: 10-F431587
5mgTo inquire10mgTo inquire25mgTo inquire50mgTo inquire100mgTo inquire250mgTo inquireTert-Butyl (6-(hydroxymethyl)pyrimidin-4-yl)carbamate
CAS:Purity:95.0%Molecular weight:225.24800109863284-[4-(benzyloxy)phenyl]-6-(furan-2-yl)pyrimidin-2-amine
CAS:Purity:95.0%Molecular weight:343.3859863281254-(4-tert-butylphenyl)-6-(thiophen-2-yl)pyrimidin-2-amine
CAS:Purity:95.0%Molecular weight:309.42999267578125N-Benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-methyladenosine
CAS:Purity:95%Molecular weight:687.753ethyl 2-morpholin-4-yl-4-(trifluoromethyl)pyrimidine-5-carboxylate
Molecular weight:305.25698852539066-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-9H-purine
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:277.2600097656255-Azido Oseltamivir
CAS:Controlled Product<p>Applications Intermediate in the production of Oseltamivir. It is a COVID19-related research product.<br>References Kim, C., et al.: J. Med. Chem., 41, 2451 (1998), Carbain, B., et al.: Chem. Med. Chem., 4, 335 (2009),<br></p>Formula:C16H26N4O4Color and Shape:NeatMolecular weight:338.404-(2H-1,3-benzodioxol-5-yl)-6-(furan-2-yl)pyrimidin-2-amine
CAS:Purity:95.0%Molecular weight:281.270996093754-(2,5-dimethoxyphenyl)-6-(3,4-dimethylphenyl)pyrimidin-2-amine
CAS:Purity:95.0%Molecular weight:335.4070129394531Ethyl 2-(2-(methylamino)pyrimidin-4-yl)-1H-indole-5-carboxylate
CAS:Purity:95.0%Color and Shape:Liquid, No data available.Molecular weight:296.32998657226561-(5-Bromopyrimidin-2-yl)-1H-benzo[d]imidazol-2(3H)-one
CAS:Purity:95.0%Molecular weight:291.1080017089844Ethyl 2-(2-(dimethylamino)pyrimidin-4-yl)-1H-indole-5-carboxylate
CAS:Purity:95.0%Molecular weight:310.356994628906254-(5-methylthiophen-2-yl)-6-(thiophen-2-yl)pyrimidin-2-amine
CAS:Purity:95.0%Molecular weight:273.36999511718752-[5-amino-3-(2-furyl)-1H-pyrazol-1-yl]-5,6-dimethylpyrimidin-4(3H)-one
CAS:Purity:95.0%Molecular weight:271.27999877929695-(3-Chloro-4-fluorophenyl)-3-methyl-3-(pyrimidin-5-ylmethyl)indolin-2-one
CAS:Purity:95.0%Molecular weight:367.809997558593754-(Chloromethyl)-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide
CAS:Purity:95+%Molecular weight:429.91000366210949-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-3H-purin-6-one
CAS:Purity:97%Molecular weight:270.22000122070311-(4-((6-CHLORO-2-METHYLPYRIMIDIN-4-YL)AMINO)-3-FLUOROPHENYL)-3-(4-FLUOROPHENYL)UREA
Purity:95.0%Molecular weight:389.79000854492191-(Naphthalen-2-yl)-3-(2-oxo-2-(pyrrolidin-1-yl)ethyl)urea
CAS:Purity:98%Molecular weight:297.35800170898442-(1-naphthyl)pyrimidine-5-carbaldehyde
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:234.257995605468752,3-Diamino-6-(trifluoromethyl)-4(3H)-pyrimidinone
CAS:Formula:C5H5F3N4OPurity:99.0%Color and Shape:SolidMolecular weight:194.117(S)-Methyl 2-benzamido-5-guanidinopentanoate hydrochloride
CAS:Formula:C14H21ClN4O3Purity:95.0%Molecular weight:328.8N-Acetyl Memantine
CAS:Controlled Product<p>Applications N-Acetyl Memantine is an intermediate used for preparation of Memantine (M218000).<br>References Gerzon, K., et al.: J. Med. Chem., 6, 760 (1963), Reddy, J., et al.: Org. Process Res. Dev., 11, 268 (2007),<br></p>Formula:C14H23NOColor and Shape:WhiteMolecular weight:221.34Ormetoprim
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications It is a potent and selective inhibitor of bacterial dihydrofolate reductase, the enzyme responsible for the NADPH-dependent reduction of 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate. Antibacterial.This compound is a contaminant of emerging concern (CECs).<br>References Manius, G.J., et al.: Anal. Profiles Drug Subs., 7, 445 (1978), Roth, B., et al.: J. Med. Chem., 23, 379 (1980), Brogden, R.N., et al.: Drugs, 23, 405 (1982),<br></p>Formula:C14H18N4O2Color and Shape:Off-WhiteMolecular weight:274.32Isonicotinic Acid
CAS:<p>Applications Used in the biological study of differentiation induced by nicotinic acid, nicotinamide and isonicotinic acid in human leukemia cell lines.<br>References Zeilinger, S., et al.: J. Biol. Chem., 271, 25624 (1996), Panagiotou, G., et al.: J. Biotechnol., 118, 304 (2005),<br></p>Formula:C6H5NO2Color and Shape:Light BrownMolecular weight:123.11N-Butyldeoxynojirimycin Hydrochloride
CAS:Controlled Product<p>Applications An inhibitor of a-glucosidase 1 as well as being an inhibitor of HIV cytopathicity. N-Butyldeoxynojirimycin has recently been used to retard lipid storage in the central nervous system of an animal model of Tay-Sachs disease.1-Deoxynojirimycin derivatives as selective inhibitors of glucosylceramide metabolism in man.<br>References Hettkamp, H., et al.: Eur. J. Biochem., 142, 85 (1984), Szumilo, T., et al.: Arch. Biochem. Biophys., 247, 261 (1986), Fleet, G.W.J., et al.: FEBS Letters, 237, Number 1,2, 128 (1988), Kolter, T., et al.: Angew. Chem. Int. Ed. Engl., 36, 1955 (1997),<br></p>Formula:C10H21NO4·ClHColor and Shape:NeatMolecular weight:255.747-Hydroxy Methotrexate Ammonium
CAS:Controlled Product<p>Applications 7-Hydroxy Methotrexate Ammonium Salt is a metabolite of Methotrexate (M260675), which is used as an antineoplastic and antirheumatic.<br>References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958), Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985),<br></p>Formula:C20H22N8O6·NH3Color and Shape:Yellow To BrownMolecular weight:487.47N-(3,4-Dimethoxyphenethyl)formamide
CAS:Controlled Product<p>Applications N-(3,4-Dimethoxyphenethyl)formamide is an impurity of Tetrabenazine (T284000), an antipsychotic.<br>References Schwartz, D., et al.: Biochem. Pharmacol., 15, 645 (1966),<br></p>Formula:C11H15NO3Color and Shape:NeatMolecular weight:209.242

