
Quinazoline and Quinoline Derivatives
Quinazolines and quinolines are nitrogen-containing heterocyclic compounds with aromatic structures that play a key role in the synthesis of drugs with anticancer, antimicrobial, and anti-inflammatory activity. Their derivatives feature structural modifications that optimise bioavailability and selectivity, enabling the development of new active ingredients for various therapeutic applications. These compounds are used in the manufacture of APIs for the treatment of cancer, infections, neurodegenerative diseases, and cardiovascular conditions. Additionally, quinazoline and quinoline derivatives are essential in the research of enzyme inhibitors and the design of innovative bioactive molecules.
At CymitQuimica, we offer high-purity quinazoline and quinoline derivatives for applications in chemical synthesis, pharmaceutical development, and biotechnology.
Found 65615 products of "Quinazoline and Quinoline Derivatives"
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Vibegron
CAS:<p>Vibegron (MK-4618) is an effective and selective Beta 3 adrenergic receptor agonist, used to treat overactive bladder (OAB).</p>Formula:C26H28N4O3Color and Shape:SolidMolecular weight:444.53SD-2590 HCl
CAS:<p>SD-2590 HCl is an MMP-2,-3, -9, -8, 13, and -14 inhibitor.</p>Formula:C22H26ClF3N2O7SPurity:98%Color and Shape:SolidMolecular weight:554.96Faldaprevir
CAS:<p>Faldaprevir is an orally effective, selective, non-covalent HCV NS3/4A protease inhibitor with high inhibitory activity against HCV 1a and 1b genotype.</p>Formula:C40H49BrN6O9SPurity:99.04% - 99.19%Color and Shape:SolidMolecular weight:869.82COTI-219
CAS:<p>COTI-219 is an oral inhibitor of KRAS with antitumor properties [1].</p>Formula:C17H18N6SColor and Shape:SolidMolecular weight:338.43Indinavir monohydrate
CAS:<p>Indinavir monohydrate is a potent and specific HIV protease inhibitor that appears to have good oral bioavailability.</p>Formula:C36H49N5O5Color and Shape:SolidMolecular weight:631.82Lisuride
CAS:<p>Lisuride: an oral D2 dopamine agonist, ergot derivative, used in Parkinson's, migraine, and high prolactin research.</p>Formula:C20H26N4OColor and Shape:SolidMolecular weight:338.45Macitentan (n-butyl analogue)
CAS:<p>Macitentan n-butyl analogue, an oral ETA/ETB receptor blocker, may treat IPF and PAH.</p>Formula:C20H21Br2N5O4SPurity:98%Color and Shape:SolidMolecular weight:587.29CM-352
CAS:<p>CM-352 is a metalloproteinase inhibitor that reduces brain damage and improves functional recovery in rat models of cerebral hemorrhage.</p>Formula:C24H29N3O6SPurity:99.36%Color and Shape:SolidMolecular weight:487.57Neptinib
CAS:<p>Neptinib (NEP010), a derivative of Afatinib, exhibits enhanced antitumor properties and improved pharmacokinetics when administered orally. It demonstrates a notable suppression of tumor expansion in mouse models of non-small cell lung cancer harboring various EGFR mutations. Furthermore, Neptinib effectively inhibits the EGFR kinase family, exhibiting IC 50 values of 0.24 nM for EGFR wt, 7.25 nM for EGFR L858R/T790M, 0.46 nM for EGFR L858R, and 1.79 nM for EGFR T790M.</p>Formula:C22H23ClFN5O2Color and Shape:SolidMolecular weight:443.90ZK159222
CAS:<p>ZK159222 is an effective 1α,25-(OH)2D3 receptor (VDR) agonist. ZK159222 has a partial agonistic character.</p>Formula:C32H48O5Purity:98%Color and Shape:SolidMolecular weight:512.72HU-308
CAS:<p>HU-308, a synthetic cannabinoid analogue, is a highly selective agonist of the CB2 receptor. It demonstrates an affinity for the CB2 receptor that is over 440 times greater than its affinity for the CB1 receptor, which are predominantly found in immune cells. This compound plays a crucial role in modulating the immunosuppressive effects of the endocannabinoid system (ECS). Additionally, HU-308 possesses anti-inflammatory and neuroprotective properties, and it regulates the function of microglia. Its potential applications include research into neuroinflammation and retinal diseases.</p>Formula:C27H42O3Color and Shape:SolidMolecular weight:414.62Finafloxacin
CAS:<p>Finafloxacin is a pH-activated fluoroquinolone, most effective at pH 5.0-6.0, targeting bacterial topoisomerases, used for UTIs and H. pylori infections.</p>Formula:C20H19FN4O4Color and Shape:SolidMolecular weight:398.39Arterolane
CAS:<p>Arterolane is an antimalarial compound. For against P. falciparum Ro73 and W2, the IC50s are both 1.1 nM.</p>Formula:C22H36N2O4Color and Shape:SolidMolecular weight:392.53PNU-248686A
CAS:<p>PNU-248686A is an inhibitor of matrix metalloproteinase (MMP).</p>Formula:C22H18ClNaO5S2Purity:98%Color and Shape:SolidMolecular weight:484.95UK 356618
CAS:<p>UK 356618 is a potent and selective inhibitor of matrix metalloprotease-3 (IC50: 5.9 nM).</p>Formula:C34H43N3O4Purity:98%Color and Shape:SolidMolecular weight:557.72Tofogliflozin
CAS:<p>Tofogliflozin specifically inhibits SGLT2; IC50s are 2.9 nM (human), 14.9 nM (rat), 6.4 nM (mouse).</p>Formula:C22H26O6Purity:98%Color and Shape:SolidMolecular weight:386.44Thioquinapiperifil dihydrochloride
CAS:<p>Thioquinapiperifil dihydrochloride is a potent, selective PDE-5 inhibitor (IC50: 0.074 nM) for research.</p>Formula:C24H29ClN6OSPurity:98.73%Color and Shape:SolidMolecular weight:485.05Aclidinium
CAS:<p>Aclidinium, a dual-action compound, serves as a long-acting muscarinic antagonist and a β2-adrenoceptor (β2-AR) agonist, exhibiting bronchodilator properties. It effectively reduces lung hyperinflation, enhances lung function, and prolongs exercise endurance time. This compound is commonly utilized in studies focusing on chronic obstructive pulmonary disease (COPD).</p>Formula:C26H30NO4S2Color and Shape:SolidMolecular weight:484.65SD-7300
CAS:<p>SD-7300 (SC-81490) functions as an orally active inhibitor targeting MMP-2, MMP-9, and MMP-13, exhibiting potent inhibition with K_i values of 0.03, 0.01, and 0.03 nM, respectively. By inhibiting these metalloproteinases, SD-7300 effectively reduces extracellular matrix degradation by tumor cells, thereby curbing their invasion and metastasis. Additionally, this compound acts as a dose-dependent inhibitor of mouse corneal angiogenesis and prevents interleukin-1-induced degradation of bovine cartilage. SD-7300 is applicable in the study of breast cancer.</p>Formula:C21H30F3N3O7SColor and Shape:SolidMolecular weight:525.54Obicetrapib
CAS:<p>Obicetrapib (AMG-899) is an inhibitor of cholesteryl ester transfer protein.</p>Formula:C32H31F9N4O5Purity:99.26% - >99.99%Color and Shape:SolidMolecular weight:722.6Vecabrutinib
CAS:<p>Vecabrutinib (SNS-062) is a potent and noncovalent BTK and ITK inhibitor (Kd: 0.3 nM and 2.2 nM, respectively). Vecabrutinib displays an IC50 of 24 nM for ITK.</p>Formula:C22H24ClF4N7O2Purity:99.74%Color and Shape:SolidMolecular weight:529.92Aleglitazar
CAS:<p>Aleglitazar (R1439) (R1439) is a potent dual PPARα/γ agonist, with IC50s of 38 nM and 19 nM for human PPARa and PPARγ, respectively.</p>Formula:C24H23NO5SPurity:99.03%Color and Shape:SolidMolecular weight:437.51(S)-Rasagiline
CAS:<p>(S)-Rasagiline is rasagiline S-isomer, and is an agent of anti-Parkinson.</p>Formula:C12H13NColor and Shape:SolidMolecular weight:171.24Chlorothiophene carboxylic acid (5-chlorothiophene-2-carboxylic acid)
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormula:C5H3ClO2SColor and Shape:Off-White Pale Yellow SolidMolecular weight:161.95423Ezetimibe Desfluoroaniline Analog ((3R,4S)-3-[(S)-3-(4-Fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-1-phenylazetidin-2-one)
CAS:Lactams, nesoiFormula:C24H22FNO3Color and Shape:White Off-White PowderMolecular weight:391.15837Dasatinib Related Compound A
CAS:Compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structureFormula:C22H26ClN7O3SMolecular weight:503.15064N-Acetyl-L-Leucine (Acetyl-L-leucine)
CAS:Acyclic amides (including acyclic carbamates) and their derivatives and salts thereof, nesoiFormula:C8H15NO3Color and Shape:White PowderMolecular weight:173.10519Atazanavir Benzylidenehydrazine Carbamate (Methyl [(S)-1-{[(2S,3S)-3-hydroxy-1-phenyl-4-{1-[4-(pyridin-2-yl)benzyl]-2-[4-(pyridin-2-yl)benzylidene]hydrazinyl}butan-2-yl]amino}-3,3-dimethyl-1-oxobutan-2-yl]carbamate)
CAS:Compounds containing an unfused pyridine ring in the structure, nesoiFormula:C42H46N6O4Color and Shape:Light Yellow SolidMolecular weight:698.35805Ezetimibe 2-Fluorobenzene Isomer ((3R,4S)-1-(4-fluorophenyl)-3-((S)-3-(2-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one)
CAS:Lactams, nesoiFormula:C24H21F2NO3Color and Shape:White Off-White SolidMolecular weight:409.14895Acetyl Rotigotine Hydrochloride ((S)-6-(propyl(2-(thiophen-2-yl)ethyl)amino)-5,6,7,8-tetrahydronaphthalen-1-yl acetate hydrochloride)
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormula:C21H28ClNO2SColor and Shape:Off-White SolidMolecular weight:393.15293Rivaroxaban Open Ring ((R)-5-chloro-N-(2-hydroxy-3-((4-(3-oxomorpholino)phenyl)amino)propyl)thiophene-2-carboxamide)
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormula:C18H20ClN3O4SColor and Shape:Off-White SolidMolecular weight:409.0863Methylbis(2-pyridylethyl)amine Hydrochloride (N-Methyl-N,N-bis(2-pyridin-2-yl-ethyl)amine trihydrochloride)
CAS:Compounds containing an unfused pyridine ring in the structure, nesoiFormula:C15H19N3·3HClColor and Shape:Light Brown PowderMolecular weight:241.1579Levetiracetam acid ((S)-2-(2-oxopyrrolidin-1-yl)butanoic acid)
CAS:Lactams, nesoiFormula:C8H13NO3Color and Shape:Off-White SolidMolecular weight:171.08954Dasatinib
CAS:Compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structureFormula:C22H26ClN7O2S·H2OMolecular weight:505.16629Everolimus System Suitability Mixture (This is a mixture of Everolimus, Everolimus oxepane isomer and 9-O-Hydroxyethyl Sirolimus)
Diagnostic or lab reagents on a backing, prepared diagnostic or lab reagents whether or not on a backing, whether or not in the form of kits, nesoiColor and Shape:White Yellow PowderEzetimibe Tetrahydropyran Analog ((2R,3R,6S)-N,6-bis(4-fluorophenyl)-2-(4-hydroxyphenyl)tetrahydro-2H-pyran-3-carboxamide)
CAS:Aromatic heterocyclic compounds with oxygen hetero-atom(s) only, nesoiFormula:C24H21F2NO3Color and Shape:White Off-White SolidMolecular weight:409.14895(4-Methylbenzoyl)trifluoroacetone (1,1,1-Trifluoro-4-hydroxy-4-(4-methylphenyl)-3-buten-2-one)
CAS:Ketones and quinones, w/not with other oxygen function,and their halogenated,sulfated,nitrated,or nitrosated derivatives, nesoiFormula:C11H9F3O2Color and Shape:White SolidMolecular weight:230.05546Desmethoxy Omeprazole (2-(((3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-5-methoxy-1H-benzo[d]imidazole; 2-[(RS)-[(3,5-Dimethylpyridin-2-yl)methyl]sulfinyl]-5-methoxy-1H-benzimidazole) (DISCONTINUED)
CAS:Compounds containing an unfused pyridine ring in the structure, nesoiFormula:C16H17N3O2SColor and Shape:White Off-White SolidMolecular weight:315.10415Ezetimibe Ketone ((3R,4S)-1-(4-Fluorophenyl)-3-[3-(4-fluorophenyl)-3-oxopropyl]-4-(4-hydroxyphenyl)azetidin-2-one)
CAS:Lactams, nesoiFormula:C24H19F2NO3Color and Shape:White SolidMolecular weight:407.1333Methoxyamiodarone ([2-[(1RS)-1-Methoxybutyl]benzofuran-3-yl][4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl]methanone) (DISCONTINUED)
CAS:Aromatic heterocyclic compounds with oxygen hetero-atom(s) only, nesoiFormula:C26H31I2NO4Color and Shape:Colorless GelMolecular weight:675.03425(-)-3,4-Dihydroxynorephedrine
CAS:Formula:C9H13NO3Purity:98%Color and Shape:SolidMolecular weight:183.2044Ref: 4Z-S-1749
Discontinued productRef: 4Z-E-4878
Discontinued productRef: 4Z-M-1246
Discontinued productRef: 4Z-O-02166
Discontinued productRef: 4Z-E-6326
Discontinued productRef: 4Z-M-8690
Discontinued productRef: 4Z-A-253028
Discontinued productRef: 4Z-L-0365
Discontinued productRef: 4Z-P-0144
Discontinued productEtoricoxib Impurity 24
CAS:Formula:C3H4ClNOColor and Shape:White To Off-White SolidMolecular weight:105.52Ref: 4Z-E-4530
Discontinued productRef: 4Z-N-1765
Discontinued productRef: 4Z-A-8466
Discontinued productRef: 4Z-P-26112
Discontinued productRef: 4Z-L-4271
Discontinued productRef: 4Z-E-4841
Discontinued productRef: 4Z-E-1022
Discontinued productRef: 4Z-R-0659
Discontinued productRef: 4Z-T-3365
Discontinued productRef: 4Z-L-4429
Discontinued productRef: 4Z-B-0820
Discontinued productRef: 4Z-K-031117
Discontinued productRef: 4Z-V-064028
Discontinued productRef: 4Z-L-1057
Discontinued productRef: 4Z-D-108023
Discontinued productRef: 4Z-I-0815
Discontinued productRef: 4Z-P-240004
Discontinued productRef: 4Z-D-245010
Discontinued productRef: 4Z-C-0135
Discontinued productRef: 4Z-N-0512
Discontinued productRef: 4Z-P-646
Discontinued productRef: 4Z-C-0334
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Discontinued productRef: 4Z-A-59100
Discontinued productRef: 4Z-L-0413
Discontinued productRef: 4Z-A-8445
Discontinued productRef: 4Z-K-031112
Discontinued productRef: 4Z-T-414010
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Discontinued productRef: 4Z-T-184011
Discontinued productRef: 4Z-T-81182
Discontinued productRef: 4Z-I-1228
Discontinued productRef: 4Z-M-8668
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Discontinued productRef: 4Z-P-142111
Discontinued productRef: 4Z-A-102113
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Discontinued productRef: 4Z-B-1644
Discontinued productRef: 4Z-P-368047
Discontinued productPerampanel Impurity 28
CAS:Formula:C28H20N2O2Color and Shape:White To Off-White SolidMolecular weight:416.48Ref: 4Z-P-181030
Discontinued productRef: 4Z-I-515
Discontinued productRef: 4Z-F-188015
Discontinued productRef: 4Z-F-1838
Discontinued productRef: 4Z-O-0145
Discontinued productRef: 4Z-P-5536
Discontinued productRef: 4Z-R-093071
Discontinued productRef: 4Z-R-093030
Discontinued productRef: 4Z-T-4949
Discontinued productRef: 4Z-A-315061
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