Quinazoline and Quinoline Derivatives
Quinazolines and quinolines are nitrogen-containing heterocyclic compounds with aromatic structures that play a key role in the synthesis of drugs with anticancer, antimicrobial, and anti-inflammatory activity. Their derivatives feature structural modifications that optimise bioavailability and selectivity, enabling the development of new active ingredients for various therapeutic applications. These compounds are used in the manufacture of APIs for the treatment of cancer, infections, neurodegenerative diseases, and cardiovascular conditions. Additionally, quinazoline and quinoline derivatives are essential in the research of enzyme inhibitors and the design of innovative bioactive molecules.
At CymitQuimica, we offer high-purity quinazoline and quinoline derivatives for applications in chemical synthesis, pharmaceutical development, and biotechnology.
Found 65630 products of "Quinazoline and Quinoline Derivatives"
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12-Hydroxy Irinotecan (Mixture of Diastereomers)
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications A metabolite of Irinotecan (I767500) found in human bile and urine.<br>References Lokeic, F. et al.: Clin. Cancer Res., 2, 1943 (1996); Dodds, H.M. et al.: Anti-cancer Drug Des., 16, 239 (2001); Kunimoto, T., et al.: Cancer Res., 47, 5944 (1987); Shimada, Y., et al.: J. Clin. Oncol., 11, 909 (1993);<br></p>Formula:C33H38N4O7Color and Shape:Off-WhiteMolecular weight:602.686-Chloro-7-methoxy-2-methyl-3-(4-(4-(trifluoromethoxy)phenoxy)phenyl)quinolin-4(1H)-one
CAS:Purity:98.0%Molecular weight:475.8500061035156Ref: 10-F549703
5mgTo inquire10mgTo inquire25mgTo inquire50mgTo inquire100mgTo inquire250mgTo inquirerac Phenylephrine Hydrochloride
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Phenylephrine is a selective α1-adrenergic receptor agonist used as a decongestant. Phenylephrine lowers intraocular pressure and is used as an agent to dilate the pupil.<br>References Lorenzetti, O.J. et al.: Exp. Eye Res., 12, 80 (1971); Ando, J. et al.: Nip. Yakur. Zas., 61, 471 (1965);<br></p>Formula:C9H14ClNO2Color and Shape:NeatMolecular weight:203.67Tazarotene
CAS:<p>Applications An acetylenic retinoid prodrug converted to the active metabolite, Tazarotenic acid, with selective affinity for retinoic acid receptors RARβ and RARγ. Antiacne; antipsoriatic. Used in treatment of photodamaged skin.<br>References Tang-Liu, D.D.-S., et al.: Clin. Pharmacokinet., 37, 273 (1999), Roeder, A., et al.: Skin Pharmacol. Physiol., 17, 111 (2004),<br></p>Formula:C21H21NO2SColor and Shape:Light YellowMolecular weight:351.463-Hydroxy Nevirapine
CAS:Controlled Product<p>Applications A metabolite of Nevirapine (N391275).<br>References Rettie, A., et al.: J. Biol. Chem., 263, 13733 (1988), Lamson, M., et al.: Biopharm. Drug Dispos., 20, 285 (1999), Guengerich, F., et al.: Chem. Res. Toxicol., 14, 611 (2001), Lu, W., et al.: Drug Metab. Dispos., 36, 1624 (2008),<br></p>Formula:C15H14N4O2Color and Shape:NeatMolecular weight:282.30DL-Norepinephrine-d6 Hydrochloride, 85%
CAS:Controlled Product<p>Applications Antagonist of dibutyryl cyclic AMP in the regulation of narcosis. Norepinephrine modulates human dendritic cell activation by altering cytokine release.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Piguet, P., et al.: J. Exp. Med., 173, 673 (1991), Hosoi, J., et al.: Nature, 363, 159 (1993), Elenkov, I., et al.: Pharmacol. Rev., 52, 595 (2000), Kaplan, D., et al.: Immunity, 23, 611 (2005),<br></p>Formula:C82H6H5NO3·ClHPurity:85%Color and Shape:NeatMolecular weight:211.68rac trans-Loxoprofen Alcohol
CAS:<p>Applications The cis-alcohol metabolite of Loxoprofen (L472900).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Terada, A., et al.: J. Med. Chem., 27, 212 (1984), Sugimoto, M., et al.: Biochem. Pharmacol., 42, 2363 (1991), Riendeau, D., et al.: Bioorg. Med. Chem. Lett., 14, 1201 (2004),<br></p>Formula:C15H20O3Color and Shape:NeatMolecular weight:248.32(aR)-3-Hydroxy-a-[[methyl(phenylmethyl)amino]methyl]-benzenemethanol
CAS:<p>Impurity Phenylephrine USP Related Compound D<br>Applications (αR)-3-Hydroxy-α-[[methyl(phenylmethyl)amino]methyl]-benzenemethanol (Phenylephrine USP Related Compound D) is a derivative of (R)-Phenylephrine (P320640, HCl salt) which is an α-Adrenergic agonist.<br>References Warren, M.R., et al.: J. Pharmacol. Exp. Ther., 86, 284 (1946); Gaglia, C.A., et al.: Anal. Profiles Drug Subs., 3, 483 (1974)<br></p>Formula:C16H19NO2Color and Shape:NeatMolecular weight:257.33Pyrazinamide
CAS:Controlled Product<p>Applications Antibacterial (tuberculostatic).<br>References Weiner, I.M., et al.: J. Pharmacol. Exp. Ther., 180, 411 (1972), Feldner, E., et al.: Anal. Profiles Drug Subs., 12, 433 (1983)<br></p>Formula:C5H5N3OColor and Shape:White To Off-WhiteMolecular weight:123.118-benzyl-4-(pyridine-4-carbonyl)-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid
CAS:Purity:95.0%Molecular weight:381.4320068359375(S)-2-Aminobutyramide Hydrochloride
CAS:Controlled Product<p>Impurity Levetiracetam USP Related Compound B<br>Applications Levetiracetam USP Related Compound B<br></p>Formula:C4H10N2O·ClHColor and Shape:White To Off-WhiteMolecular weight:138.601-[5-(Hydroxymethyl)-2-furyl]-2-methyl-1,2,3,4-tetrahydroisochinolin-4,8-diol
CAS:Controlled Product<p>Applications 1-[5-(Hydroxymethyl)-2-furyl]-2-methyl-1,2,3,4-tetrahydroisochinolin-4,8-diol is a degradation product of phenylephrine during the synthesis of the anti-cold medicine.<br>References Dousa, M. et al.: J. Pharm. Biomed. Anal., 55, 949 (2011);<br></p>Formula:C15H17NO4Color and Shape:NeatMolecular weight:275.3Sulindac Sulfone Acyl-β-D-Glucuronide
CAS:Controlled Product<p>Applications Sulindac Sulfone Acyl-β-D-Glucuronide is the major metabolite of the non-steroidal anti-inflammatory drug Sulindac (S699215) in plasma and urine.<br>References Hucker, H.B., et al.: Drug Metab. Dispos., 1, 721 (1973),<br></p>Formula:C26H25FO10SColor and Shape:NeatMolecular weight:548.53Desmethyl Doxylamine
CAS:<p>Impurity Doxylamine EP Impurity C<br>Applications Desmethyl Doxylamine is an impurity of Doxylamine (D562000), an H1 Histamine receptor antagonist used as a antihistaminic and sedative agent.<br>References Pande, S.S., et al.: Int. J. Pharmtech. Res., 3, 209 (2011); Tiford, C.H., et al.: J. Am. Chem. Soc., 70, 4001 (1948);<br></p>Formula:C16H20N2OColor and Shape:NeatMolecular weight:256.342-((6-Chloropyridin-3-yl)methyl)isoindoline-1,3-dione
CAS:Purity:95.0%Molecular weight:272.69000244140625Toltrazuril
CAS:Controlled Product<p>Applications A triazinetrione anticoccidial. Coccidiostat.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Eberts, T., et al.: Clin. Chem., 25, 1440 (1979), Goodwin, M., et al.: Avian Dis., 29, 630 (1985), Sorensen, S., et al.: Clin. Chim. Acta, 264, 103 (1997), Conway, D., et al.: Poult. Sci., 280, 426 (2001),<br></p>Formula:C18H14F3N3O4SColor and Shape:Off WhiteMolecular weight:425.38Dutasteride β-Dimer
CAS:Controlled Product<p>Applications Dutasteride β-Dimer is a dimer impurity of Dutasteride (D735000); a dual inhibitor of 5α-reductase isoenzymes type 1 and 2. Dutasteride is structurally related to Finasteride (F342000) and is used in the treatment of benign prostatic hyperplasia.<br>References Bakshi, R.K., et al.: J. Med. Chem., 38, 3189 (1995); Gisleskog, P.O., et al.: Brit. J. Clin. Pharmacol., 47, 53 (1999); Djavan, B., et al.: Expert Opin. Pharmacother., 6, 311 (2005)<br></p>Formula:C46H55F6N3O4Color and Shape:NeatMolecular weight:827.94N-Desmethyl Asenapine Hydrochloride
CAS:<p>Applications Asenapine (A788000) metabolite.<br>References Lobell, M., et al.: J. Pharm., Sci., 92, 360 (2003), Zhang, L., et al.: Pharm. Res., 25, 1902 (2008), Toulmin, A., et al.: J. Med. Chem., 51, 3720 (2008),<br></p>Formula:C16H14ClNO·ClHColor and Shape:NeatMolecular weight:308.202-Ethyl-2-methyl-succinonitrile
CAS:Controlled Product<p>Applications An intermediate in the preparation of Ethosuximide.<br></p>Formula:C7H10N2Color and Shape:NeatMolecular weight:122.176-Bromo-5-hydroxy-1-methyl-2-[(phenylthio)methyl]-1H-indole-3-carboxylic Acid Ethyl Ester
CAS:Controlled ProductFormula:C19H18BrNO3SColor and Shape:Off White SolidMolecular weight:420.32(3S-trans)-5-[[4-(4-Fluorophenyl)-3-piperidinyl]methoxy]-2-methoxyphenol (Paroxetine Metabolite)
CAS:Formula:C19H22FNO3Color and Shape:White SolidMolecular weight:331.383-(1-Piperazinyl)-1,2-benzisothiazole
CAS:Controlled Product<p>Impurity Ziprasidone EP Impurity A<br>Applications 3-(1-Piperazinyl)-1,2-benzisothiazole (Ziprasidone EP Impurity A) is a reagent used to synthesize Ziprasidone (Z485000, HCl salt, monohydrate), a combined serotonin (5HT2) and dopamine (D2) receptor antagonist.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Prakash, C., et al.: Brit. J. Clin. Pharmacol., 49, 35S (2000); Orjales, A., et al.: J. Med. Chem., 46, 5512 (2003); Graham, J., et al.: Bioorg. Med. Chem. Lett., 18, 489 (2008); Bench, C.J., et al.: Psychopharmacology, 112, 308 (1993), Goldstein, J.M.: Exp. Opin. Invest. Drugs, 4, 291 (1995)<br></p>Formula:C11H13N3SColor and Shape:NeatMolecular weight:219.31rac-4-Hydroxy Propranolol-d7 Hydrochloride
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications A labelled metabolite of Propranolol.<br>References Walle, T., et al.: Drug Metab. Dispos., 13, 204 (1985), Mason, R., et al.: J. Med. Chem., 34, 869 (1991), Anderson, R., et al.: Biochem. Pharmacol., 52, 341 (1996), Hung, D., et al.: J. Pharmacol. Exp. Ther., 297, 780 (2001),<br></p>Formula:C16D7H14NO3·ClHColor and Shape:Light Red To BrownMolecular weight:318.85METHYL 6-(ETHYLAMINO)-2-FLUOROPYRIDINE-3-CARBOXYLATE
CAS:Purity:95.0%Molecular weight:198.19700622558594Ticagrelor Sulfoxide (Mixture of Diastereomers)
CAS:Controlled Product<p>Applications Ticagrelor Sulfoxide is an impurity of ticagrelor (T437700). Ticagrelor, the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Used in the treatment of acute coronary syndromes (ACS).<br>References Matetzky, S., et al.: Circulation, 109, 3171 (2004), Bassand, J., et al.: Eur. Heart J., 28, 1598 (2007), Jakubowski, J., et al.: Cardiovasc. Drug Rev., 25, 357 (2007),<br></p>Formula:C23H28F2N6O5SColor and Shape:NeatMolecular weight:538.57Sodium Borohydride
CAS:<p>Applications Sodium Borohydride is used as a reagent in the reduction of amino acids and their derivatives. Also used in the catalysis of ammonia borane dehydrogenation.<br> E0<br>References McKennon, M. et al.: J. Org. Chem., 58, 3568 (1993); Denney, M. et al.: J. Am. Chem. Soc., 128, 12048 (2006);<br></p>Formula:BH4NaColor and Shape:White To Off-WhiteMolecular weight:37.83Chlorpromazine-d6 Oxalate (N,N-dimethyl-d6)
CAS:Controlled Product<p>Applications Chlorpromazine-d6 Oxalate (N,N-dimethyl-d6) (CAS# 1276197-23-9) is a useful isotopically labeled research compound.<br></p>Formula:C17D6H13ClN2S·C2H2O4Color and Shape:Off-WhiteMolecular weight:414.933-Acetamidophthalic Acid
CAS:<p>Impurity Apremilast EP Impurity B<br>Applications 3-Acetamidophthalic Acid is an impurity of Apremilast (A729700); an oral phosphodiesterase 4 inhibitor used in the treatment of psoriatic arthritis. Apremilast EP Impurity B<br>References Gan, E. et al.: BioDrugs, 27, 359 (2013); Pathan, E. et al.: Annal. Rheum. DIs., 72, 1475 (2013); Hoffmann, M., et al.: Xenobiotica, 41, 1063 (2011)<br></p>Formula:C10H9NO5Color and Shape:NeatMolecular weight:223.18α,α,α’,α’-Tetramethyl-5-(dibromomethyl)-1,3-benzenediacetonitrile
CAS:Controlled Product<p>Impurity Anastrozole EP Impurity D / Anastrozole USP Related Compound E<br>Applications α,α,α’,α’-Tetramethyl-5-(dibromomethyl)-1,3-benzenediacetonitrile (Anastrozole EP Impurity D) an impurity of Anastrozole (A637425) (impurity E).<br>References Ge, Z., et al.: J. Med. Chem., 13, 146 (2003),<br></p>Formula:C15H16Br2N2Color and Shape:WhiteMolecular weight:384.11N-Nitroso Varenicline
CAS:Controlled Product<p>Applications N-Nitroso Varenicline is a derivative of Varenicline (V215635(M)), which is a useful medication for smoking cessation.<br>References Hart, E., et al.: Behavioural Brain Research, 397, 112887 (2021)<br></p>Formula:C13H12N4OColor and Shape:NeatMolecular weight:240.2614-Hydroxy-N-desbutyl Bupivacaine
CAS:Controlled Product<p>Applications Bupivacaine metabolite.<br>References Goehl, T. J. et al.: Xenobiotica 3, 761 (1973)<br></p>Formula:C14H20N2O2Color and Shape:NeatMolecular weight:248.324,5-O-(1-Methylethylidene)-β-D-fructopyranose
CAS:Controlled Product<p>Applications Intermediate in the preparation of 2,3-Desisopropylidene Topiramate, a metabolite of Topiramate<br></p>Formula:C9H16O6Color and Shape:NeatMolecular weight:220.22Bicalutamide
CAS:Controlled Product<p>Applications Non-steroidal peripherally active antiandrogen. Used as an antiandrogen, antineoplastic (hormonal); Non-steroidal androgen receptor antagonist that binds the androgen receptor and prevents its activation.<br>References Tucker, H., et al.: J. Med. Chem., 31, 954 (1988), Cockshott, I.D., et al.: Eur. Urol., 18, Suppl. 3, 10 (1990), Cockshott, I., et al.: Br. J. Clin. Pharm., 36, 339 (1993), McKillop, D., et al.: Xenobiotica, 25, 623 (1995),<br></p>Formula:C18H14F4N2O4SColor and Shape:WhiteMolecular weight:430.371-(4-Chloromethyl-2-thiazoyl)guanidine Hydrochloride Salt
CAS:Controlled Product<p>Stability Moisture Sensitive<br>Applications Reagent used to produce many guanidine based pharmaceuticals<br></p>Formula:C5H7ClN4S·ClHColor and Shape:White To Light BrownMolecular weight:227.114-Hydroxy Omeprazole Preparation Kit
CAS:Controlled ProductFormula:C16H17N3O3SColor and Shape:Off White SolidMolecular weight:331.39Etoricoxib
CAS:Controlled ProductFormula:C18H15ClN2O2SColor and Shape:Off-WhiteMolecular weight:358.846-Allyl-8b-carboxyergoline
CAS:<p>Impurity Cabergoline EP Impurity A<br>Applications 6-Allyl-8β-carboxyergoline is a metabolite of cabergoline (C050000) which is a dopamine D2-receptor agonist.<br>References Brambilla, E., et al.: Eur. J. Med. Chem., 24, 421 (1989), Ferrari, C., et al.: J. Clin. Endocrinol. Metab., 68, 1201 (1989), Hutton, J.T., et al.: Neurology, 46, 1062 (1996)<br></p>Formula:C18H20N2O2Color and Shape:Light Beige SolidMolecular weight:296.3636Ticagrelor Epimer
Controlled Product<p>Applications Ticagrelor Epimer is an epimer impurity of Ticagrelor (T437700). Ticagrelor (T437700), the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Used in the treatment of acute coronary syndromes (ACS).<br>References Matetzky, S., et al.: Circulation, 109, 3171 (2004), Bassand, J., et al.: Eur. Heart J., 28, 1598 (2007), Jakubowski, J., et al.: Cardiovasc. Drug Rev., 25, 357 (2007),<br></p>Formula:C23H28F2N6O4SColor and Shape:NeatMolecular weight:522.575-Aminoimidazole-4-carboxamide Lactose Adduct
Controlled Product<p>Stability Hygroscopic<br>Applications 5-Aminoimidazole-4-carboxamide Lactose Adduct is a lactose adduct of 5-Aminoimidazole-4-carboxamide (A611690), a metabolite of Temozolomide (T017775).<br>References Jaeken, J., et al.: Lancet, 2, 1058 (1984), Baggott, J., et al.: Biochem. J., 236, 193 (1986), Baggott, J., et al.: Arch. Dermatol., 135, 813 (1999)<br></p>Formula:C16H26N4O11Color and Shape:NeatMolecular weight:450.43-[3-(2,3-Dihydro-2-oxo-1H-benzimidazol-1-yl)propyl] Domperidone (Domperidone Impurity D)
CAS:<p>Impurity Domperidone EP Impurity D<br>Applications An impurity of the gastrokinetic and antinauseant drug Domperidone (D531100).<br></p>Formula:C32H34ClN7O3Purity:>90%Color and Shape:White To Off-WhiteMolecular weight:600.11tau-Fluvalinate (Mixture of Diastereomers)
CAS:<p>Applications τ-Fluvalinate is a synthetic pyrethroid aracacide. τ-Fluvalinate is commonly used to control Varroa jacobsoni (a parasitic mite) in honey bee colonies.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Delaplane, K.S. et al.: J. Econ. Entomol., 88, 1206 (1995); Ferrer-Dufol, M. et al.: J. Apicul. Res., 34, 147 (1995); Lindberg, C.M. et al.: J. Econ. Entomol., 93, 189 (2000);<br></p>Formula:C26H22ClF3N2O3Color and Shape:Light YellowMolecular weight:502.914'-Formylbiphenyl-2-carbonitrile
CAS:Controlled Product<p>Applications 4'-Formylbiphenyl-2-carbonitrile is an impurity of Telmisartan (T017000), an angiotensin II receptor antagonist.<br>References Goossen, L.J., et al.: J. Org. Chem., 72, 7473 (2007);<br></p>Formula:C14H9NOColor and Shape:NeatMolecular weight:207.2274(R)-(+)-Bupivacaine Hydrochloride
CAS:<p>Applications (R)-(+)-Bupivacaine Hydrochloride is a local anaesthetic used for epidural and intrathecal anaesthesia.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Tullar, B., et al.: J. Med. Chem., 14, 891 (1971), Schmidt, A., et al.: Pharm. Res., 22, 2121 (2005),<br></p>Formula:C18H28N2O·HClColor and Shape:NeatMolecular weight:324.89S-(-)-Sulpiride-d3
CAS:Controlled Product<p>Applications Labelled S-(-)-Sulpiride (S689140). Dopamine D2 and D3-receptor antagonist. Antipsychotic; antidepressant; antiemetic.<br>References Pitre, D., et al.: Anal. Profiles Drug Subs., 17, 607 (1988), Wagstaff, A.J., et al.: CNS Drugs, 2, 313 (1994),<br></p>Formula:C152H3H20N3O4SColor and Shape:White To Light GreenMolecular weight:344.44N-Nitroso Frovatriptan 1
Formula:C14H16N4O2Color and Shape:Off-White To Light YellowMolecular weight:272.3Loratadine
CAS:Controlled Product<p>Applications A nonsedating-type histamine H1-receptor.<br>References Bruttmann, G., et al.: J. Allergy Clin. Immunol., 83, 411 (1989), Haria, M., et al.: Drugs, 48, 617 (1994)<br></p>Formula:C22H23ClN2O2Color and Shape:WhiteMolecular weight:382.88
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