Quinazoline and Quinoline Derivatives
Quinazolines and quinolines are nitrogen-containing heterocyclic compounds with aromatic structures that play a key role in the synthesis of drugs with anticancer, antimicrobial, and anti-inflammatory activity. Their derivatives feature structural modifications that optimise bioavailability and selectivity, enabling the development of new active ingredients for various therapeutic applications. These compounds are used in the manufacture of APIs for the treatment of cancer, infections, neurodegenerative diseases, and cardiovascular conditions. Additionally, quinazoline and quinoline derivatives are essential in the research of enzyme inhibitors and the design of innovative bioactive molecules.
At CymitQuimica, we offer high-purity quinazoline and quinoline derivatives for applications in chemical synthesis, pharmaceutical development, and biotechnology.
Found 65924 products of "Quinazoline and Quinoline Derivatives"
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N,N'-Dicyclohexylurea
CAS:Controlled Product<p>Impurity Lomustine USP Related Compound C<br>Applications N,N'-Dicyclohexylurea,is a substituted Urea (U822500) compound, which has shown to be a potent inhibitor of juvenile hormone epoxide hydrolase (JHEH) of the tobacco hornworm M. sexta. Lomustine USP Related Compound C.<br>References Garriga, M., et al.: Chemosphere, 82, 1604 (2011)<br></p>Formula:C13H24N2OColor and Shape:Light YellowMolecular weight:224.34Amisulpride N-Oxide
CAS:Controlled Product<p>Impurity Amisulpride EP Impurity F<br>Applications Amisulpride N-Oxide is an impurity of Amisulpride (A633250). Amisulpride N-Oxide was identified as a photodegradation product of Amisulpride. Amisulpride EP Impurity F<br>References Moulin, A., et al.: Eur. J. Drug Metab. Pharmcokinet., 3, 507 (1991), Chatterjee, B., et al.: J. Biotechnol., 3, 235 (2008), Breier, A., et al.: J. Pharm. Biomed. Anal., 46, 250 (2008),<br></p>Formula:C17H27N3O5SColor and Shape:White To Off-WhiteMolecular weight:385.482-(5-amino-3-cyclopropyl-1H-pyrazol-1-yl)-5-ethyl-6-methylpyrimidin-4(3H)-one
CAS:Purity:95.0%Molecular weight:259.31298828125Nilotinib-d6
CAS:Controlled Product<p>Applications Nilotinib-d6, is the labeled analogue of Nilotinib (N465300), which might be useful in treatment of chronic myelogenous leukemia. It is a COVID19-related research product.<br>References Corbin, A., et al.: J. Biol. Chem., 277, 32214(2002), Golemovic, M., et al.: Clin. Cancer Res., 11, 4941 (2005), Gleixner, K., et al.: Blood, 107, 752 (2006), Nicolini, F., et al.: Leukemia, 20, 1061 (2006),<br></p>Formula:C282H6H16F3N7OColor and Shape:Off-White To Light BeigeMolecular weight:535.55Ethionamide
CAS:<p>Applications Antibacterial (tuberculostatic).<br>References Banerjee, A., et al.: Science, 263, 227 (1994), Newton, G., et al.: J. Bacteriol., 178, 1990 (1996), Baulard, A., et al.: J. Biol. Chem., 275, 28326 (2000), Koledin, T., et al.: Arch. Microbiol., 178, 331 (2002), Cardoso, R., et al.: Antimicrob. Agents Chemother., 48, 3373 (2004),<br></p>Formula:C8H10N2SColor and Shape:NeatMolecular weight:166.24Argatroban monohydrate
CAS:Controlled ProductFormula:C23H36N6O5S·H2OColor and Shape:NeatMolecular weight:526.654-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-ol
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:319.7200012207031rac-Vigabatrin-13C,d2 (Major)
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Labelled Vigabatrin. A novel antiepileptic drug. Antidepressant; antipsychotic; anxiolytic.<br>References Vajda, F., et al.: Clin. Neurosci., 7, 88 (2000), Beghi, E., et al.: Lancet. Neurol., 3, 618 (2004), Sagirli, O., et al.: J. Pharmaceut. Biomed., 42, 618 (2006),<br></p>Formula:C513CH9D2NO2Color and Shape:White To Dark YellowMolecular weight:132.16Sodium 2-(6-methylpyridin-2-yl)acetate
CAS:Purity:95.0%Color and Shape:Solid, Grey powderMolecular weight:173.147003173828122-(4-Methoxy-3-methylphenyl)-5-(3-methoxyphenyl)thiophene
CAS:Purity:95.0%Molecular weight:310.4100036621094Phenformin Hydrochloride
CAS:<p>Applications It is an anti-diabetic drug from the biguanide class.<br>References Moody, J.E., Anal. Profiles Drug Subs., 4, 319 (1975),<br></p>Formula:C10H15N5·ClHColor and Shape:NeatMolecular weight:241.72N-Acetyl-(+)-Pseudoephedrine
CAS:Controlled Product<p>Applications N-Acetyl-(+)-Pseudoephedrine is the N-acetylated analogue of the non-selective adrenergic agonist (+)-Pseudoephedrine (P839350).<br>References Tanaka, K.: Yakug. Zas., 70, 220 (1950); Rodriguez, M. et al.: Org. Biomol. Chem., 3, 2026 (2005);<br></p>Formula:C12H17NO2Color and Shape:WhiteMolecular weight:207.272-(3-Methyl-pyrazol-1-yl)-propionic acid methyl ester
CAS:Formula:C8H12N2O2Color and Shape:LiquidMolecular weight:168.196Pericyazine
CAS:Controlled Product<p>Applications Psychotherapeutic phenothiazine. Antipsychotic.<br>References Schafer, et al.: Toxicol. Appl. Pharmacol., 21, 315 (1972), Kaye, J., et al.: Br. J. Clin. Pharmacol., 56, 569 (2003), Tschoner, A., et al.: Pharmacopsychiatry, 42, 29 (2009),<br></p>Formula:C21H23N3OSColor and Shape:Light Yellow To YellowMolecular weight:365.492-[(5-amino-1,3,4-thiadiazol-2-yl)sulfanyl]-n-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1h-pyrazol-4-yl)propanamide
CAS:Purity:97%Molecular weight:390.480010986328111-Keto Oxcarbazepine
CAS:Controlled Product<p>Stability Unstable in Solution<br>Applications A keto impurity of the anticonvulsant Oxcarbazepine (O869250).<br></p>Formula:C15H10N2O3Color and Shape:NeatMolecular weight:266.252-Amino-5-methylpyridine
CAS:Controlled Product<p>Applications 2-Amino-5-methylpyridine (cas# 1603-41-4) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Francotte, P., et al.: Bioorg. Med. Chem., 16, 9948 (2008), Sundaraganesan, N., et al.: J. Mol. Struc., 891, 284 (2008), Caleta, I., et al.: J. Med. Chem., 52, 1744 (2009),<br></p>Formula:C6H8N2Color and Shape:NeatMolecular weight:108.14Empagliflozin
CAS:<p>Stability Hygroscopic<br>Applications Empagliflozin is a novel, potent and selective SGLT-2 inhibitor. It improves glycaemic control syndrome in diabetic rats.<br>References Thomas, L., et al.: Diabetes. Obesity. Metabol. 14, 94 (2012); Grempler, R., et al.: Diabetes. Obesity. Metabol., 14, 83 (2012);<br></p>Formula:C23H27ClO7Color and Shape:White To Off-WhiteMolecular weight:450.916-BROMO-5-CYANO-NICOTINIC ACID ETHYL ESTER
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:255.07099914550783-[5-(1,5-Dioxo-5-(p-fluophenylpentyl]-4(S)-phenyl-2-oxazolidinone
CAS:Controlled ProductFormula:C20H18FNO4Color and Shape:NeatMolecular weight:355.3596N-Boc-piperazine
CAS:<p>Applications N-Boc-piperazine (cas# 57260-71-6) is a compound useful in organic synthesis.<br></p>Formula:C9H18N2O2Color and Shape:NeatMolecular weight:186.25(1RS)-1-(6-Methoxy-2-naphthyl)ethanol (Naproxen Impurity K)
CAS:Controlled Product<p>Impurity Naproxen EP Impurity K<br>Applications Naproxen impurity K.<br>References Boynton, C., et al.: J. Clin. Pharmacol., 28, 512 (1988), Li, J., et al.: J. Med. Chem., 39, 1846 (1996), Monser, L., et al.: J. Pharm. Biomed. Anal., 27, 851 (2002),<br></p>Formula:C13H14O2Color and Shape:White To Light YellowMolecular weight:202.253-(5-Nitrofurfurylideneamino)hydantoic Acid
CAS:<p>Impurity Nitrofurantoin USP Related Compound A<br>Applications 3-(5-Nitrofurfurylideneamino)hydantoic Acid, is a new derivative of 5-Nitro-2-furfural, and they are proved to be bactericidal. Nitrofurantoin USP Related Compound A.<br>References Swirska, A., et al.: Rocz. Chem., 31, 1335 (1957);<br></p>Formula:C8H8N4O6Color and Shape:YellowMolecular weight:256.17rac Viloxazine-d5 Hydrochloride
CAS:Controlled Product<p>Applications Labelled Viloxazine (V312440). Antidepressant.<br>References Howe, R., et al.: J. Med. Chem., 19, 1074 (1976), Pinder, R.M., et al.: Drugs, 13, 401 (1977),<br></p>Formula:C13H15D5ClNO3Color and Shape:NeatMolecular weight:278.79Olanzapine LIP 1 Acetyl
CAS:<p>Applications Olanazpine LIP 1 Acetyl is an Olanazpine impurity. Olanazpine is an antipsychotic medicine.<br>References Perera, V., et al.: Br. J. Clin. Pharmacol., 78, 800 (2014); Pratt, N., et al.: Pharmacoepidemiol. Drug Saf., 22, 915 (2013)<br></p>Formula:C18H20N4OSColor and Shape:YellowMolecular weight:340.444-Nitro Lenalidomide
CAS:Controlled Product<p>Impurity Lenalidomide impurity<br>Applications Lenalidomide (L328000) analog. Lenalidomide impurity; Lenalidomide intermediate.<br>References Hashimoto, Y., et al.: Bioorg. Med. Chem., 10, 461 (2002),<br></p>Formula:C13H11N3O5Color and Shape:NeatMolecular weight:289.242-(1-Hydroxyethyl) Promazine Sulfoxide (mixture of diastereomers)
CAS:<p>Applications A metabolite of Promazine (P756300).<br>References Dewey, E.A., et al.: Drug Metab. Dispos., 9, 30 (1981), Kronstrand, R., et al.: J. Anal. Toxicol., 27, 464 (2003),<br></p>Formula:C19H24N2O2SColor and Shape:NeatMolecular weight:344.47Dechloro-Rivaroxaban
CAS:Controlled Product<p>Applications Dechloro-Rivaroxaban is an impurity of Rivaroxaban (R538000), which is a novel antithrombotic agent. A highly potent and selective, direct FXa inhibitor.<br>References Ansell, J., et al.: Drugs, 64, 1 (2004), Eriksson, B., et al.: J. Thromb. Haemost., 3, 103 (2005), Kubitza, D., et al.: Clin. Pharmacol. Ther., 78, 412 (2005),<br></p>Formula:C19H19N3O5SColor and Shape:NeatMolecular weight:401.44Maraviroc-d6
CAS:Controlled Product<p>Applications Potent, non-competitive CCR5 receptor antagonist; inhibits binding of HIV viral coat protein gp120. Antiviral.<br>References Fumero, E., et al.: Clin. Microbiol. Infect., 9, 1077 (2003), Walker, D.K., et al.: Drug Metab. Dispos., 33, 587 (2005), Wood, A., et al.: Prog. Med. Chem., 43, 239 (2005),<br></p>Formula:C29D6H35F2N5OColor and Shape:NeatMolecular weight:519.70Eperisone Hydrochloride
CAS:Controlled Product<p>Applications A spasmolytic agent related structurally to Tolperisone (T535475). Muscle relaxant (skeletal).<br>References Catterall, W., et al.: J. Biol. Chem., 256, 892 (1981), Farkas, S., et al.: Br. J. Pharmacol., 114, 1193 (1995), Xing, J., et al: Brain Res., 901, 128 (2001), Sakaue, A., et al.: J. Pharmacol. Sci., 95, 181 (2004),<br></p>Formula:C17H25NO·ClHColor and Shape:White To Off-WhiteMolecular weight:295.85(S)-Lisinopril Dimer
CAS:Controlled Product<p>Applications (S)-Lisinopril (L468985) impurity. Lisinopril Impurity G (Dimer Impurity)<br></p>Formula:C42H60N6O9Color and Shape:WhiteMolecular weight:792.963,4-Dehydro Cilostazol-d11
CAS:Controlled Product<p>Applications A labelled metabolite of Cilostazol.<br></p>Formula:C20H14D11N5O2Color and Shape:NeatMolecular weight:378.51Cilostazol-d11
CAS:Controlled Product<p>Applications A potent phosphodiesterase III A (PDE3A) inhibitor (IC50=0.2uM) and inhibitor of adenosine uptake. Has antimitogeni, antithrombotic, vasodilatory and cardiotonic properties in vivo. Also affects lipid levels in vivo.<br>References Suri, A., et al.: J. Clin. Pharmacol., 38, 144 (1998), Park, S.-W., et al.: Am. J. Cardiol., 84, 511 (1999), Tsuchikane, E., et al.: Circulation, 100, 21 (1999),<br></p>Formula:C20H16D11N5O2Color and Shape:NeatMolecular weight:380.524-Hydroxy Benzeneacetic Acid 2-(Dimethylamino)-2-oxoethyl Ester
CAS:Controlled Product<p>Applications Impurity of Camostat (C150300).<br>References Bodor, N., et al.: Pharm. Res., 3, 120 (1984), Han, L., et al.: Biochem., 46, 1432 (2007),<br></p>Formula:C12H15NO4Color and Shape:NeatMolecular weight:237.25Tadalafil
CAS:Controlled Product<p>Stability Unstable in Methanol<br>Applications Tadalafil is used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor.<br>References Carrier, S., et al.: Can. J. Urol., 10(1), 12 (2003); Doggrell, S.A., et al.: Expert Opin. Pharmacother., 6, 75 (2005); Forgue, S.T., et al.: Br. J. Clin. Pharmacol., 61, 280 (2005);<br></p>Formula:C22H19N3O4Color and Shape:White To Off-WhiteMolecular weight:389.404-[[4-Fluoro-3-(1-piperazinylcarbonyl)phenyl]methyl]-1(2H)-phthalazinone
CAS:Controlled ProductFormula:C20H19FN4O2Color and Shape:Off-WhiteMolecular weight:366.39
![2-[(5-amino-1,3,4-thiadiazol-2-yl)sulfanyl]-n-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1h-pyrazol-…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF642055.webp&w=3840&q=75)
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