Quinazoline and Quinoline Derivatives
Quinazolines and quinolines are nitrogen-containing heterocyclic compounds with aromatic structures that play a key role in the synthesis of drugs with anticancer, antimicrobial, and anti-inflammatory activity. Their derivatives feature structural modifications that optimise bioavailability and selectivity, enabling the development of new active ingredients for various therapeutic applications. These compounds are used in the manufacture of APIs for the treatment of cancer, infections, neurodegenerative diseases, and cardiovascular conditions. Additionally, quinazoline and quinoline derivatives are essential in the research of enzyme inhibitors and the design of innovative bioactive molecules.
At CymitQuimica, we offer high-purity quinazoline and quinoline derivatives for applications in chemical synthesis, pharmaceutical development, and biotechnology.
Found 65580 products of "Quinazoline and Quinoline Derivatives"
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Nor Mianserin-d6 (Major)
Controlled Product<p>Applications Nor Mianserin-d6 (Major), is a labeled analogue of Nor Mianserin (N736800), an active metabolites of Miansein (M341500) in plasma, an antidepressant.<br>References Kent, J., et al.: Lancet, 355, 911 (2000), Maurer, H., et al.: Ther. Drug Monit., 24, 117 (2002),<br></p>Formula:C17H14D6N2Color and Shape:NeatMolecular weight:258.39Praziquantel-d11
CAS:Controlled Product<p>Applications Labelled Praziquantel (P702095). Anthelmintic, effective against flatworms.<br>References Kuhn, I., et al.: Bioorg. Med. Chem., 18, 7900 (2010), Wang, W., et al.: Parasitol., 137, 1905 (2010),<br></p>Formula:C192H11H13N2O2Color and Shape:White To Light BeigeMolecular weight:323.471-[3-(Trifluoromethyl)pyridin-2-yl]piperazine hydrochloride
CAS:Purity:97.0%Molecular weight:267.67999267578125Febantel
CAS:Controlled Product<p>Applications Used as an anthelmintic.<br>References Thomas, H.: Res. Vet. Sci., 25, 290 (1978), Shmidl, J.A.: Vet. Med. Small Anim. Clin., 73, 775 (1978)<br></p>Formula:C20H22N4O6SColor and Shape:NeatMolecular weight:446.48(S)-Naproxen-d3
CAS:Controlled Product<p>Applications (S)-Naproxen-d3 is the labeled analogue of (S)-Naproxen (N377520), an anti-inflammatory, analgesic, antipyretic. A non-steroidal anti-inflammatory.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Harrison, I.T., et al.: J. Med. Chem., 13, 203 (1970)<br></p>Formula:C142H3H11O3Color and Shape:NeatMolecular weight:233.28Dihydrodiol Ibrutinib
CAS:Controlled Product<p>Applications Dihydrodiol Ibrutinib is a metabolite of Ibrutinib (I124970). Ibrutinib is a highly selective Bruton’s tyrosine kinase (Btk) irreversible inhibitor.<br>References MacGlashan, D., et. al.: Int. Immunol., 11, 475 (2011)<br></p>Formula:C25H26N6O4Color and Shape:NeatMolecular weight:474.517-Desmethylagomelatine
CAS:Controlled Product<p>Applications 7-Desmethylagomelatine, is a derivative of Agomelatine (A430000), a melatoninergic agonist and selective antagonist of 5-HT2C receptors, and has been shown to be active in several animal models of depression.Agomelatine Impurity 8<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Yous, S., et al.: J. Med. Chem., 35, 1484 (1992), Zhdanova, I., et al.: J. Clin. Endocrinol. Metab., 86, 4727 (2001), Cajochen, C., et al.: J. Pineal Res., 35, 149 (2003),<br></p>Formula:C14H15NO2Color and Shape:NeatMolecular weight:229.27Dehydro Ivabradine
CAS:Controlled ProductFormula:C27H34N2O5Color and Shape:Light Yellow To Dark BrownMolecular weight:466.57Ivacaftor
CAS:<p>Applications Ivacaftor is used in the treatment of cystic fibrosis.<br>References Clancy, J. et al.: Am. J. Resp. Crit. Care. Med., 186, 593 (2012);<br></p>Formula:C24H28N2O3Color and Shape:Off-WhiteMolecular weight:392.492-Methoxy-4-amino-5-ethylsulfonylbenzoic Acid
CAS:Controlled Product<p>Impurity Amisulpride EP Impurity E<br>Applications An impurity found in amisulpride (A633250). Amisulpride EP Impurity E<br></p>Formula:C10H13NO5SColor and Shape:WhiteMolecular weight:259.282-Thiopheneethanol Tosylate
CAS:Controlled Product<p>Applications Intermediate in the preparation of Rotigotine<br>References Janssens, F., et al.: J. Med. Chem., 29, 2290 (1986),<br></p>Formula:C13H14O3S2Color and Shape:NeatMolecular weight:282.38(E)-3-(2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)acrylonitrile
CAS:Purity:95.0%Molecular weight:314.36300659179695-Hydroxyhydantoin
CAS:Controlled Product<p>Applications 5-Hydroxyhydantoin (cas# 29410-13-7) is a compound useful in organic synthesis.<br></p>Formula:C3H4N2O3Color and Shape:WhiteMolecular weight:116.08(-)-trans-4-[4-(4’-Fluorophenyl)-3-piperidinylmethoxy]-2-methoxyphenol(Paroxetine metabolite)
CAS:Controlled ProductFormula:C19H22FNO3Color and Shape:NeatMolecular weight:331.38Apremilast-d5
CAS:Controlled ProductFormula:C22D5H19N2O7SColor and Shape:NeatMolecular weight:465.5314-((4-Bromo-2-fluorophenyl)amino)-6-methoxyquinazolin-7-ol hydrochloride
CAS:Purity:98%Molecular weight:400.63000488281252-Chloro-5-fluoro-3,8-dimethylquinoline
CAS:Formula:C11H9ClFNPurity:95.0%Color and Shape:SolidMolecular weight:209.652,6-Dimethyl-quinoline-3-carboxylic acid
CAS:Formula:C12H11NO2Purity:95.0%Color and Shape:SolidMolecular weight:201.225(R)-O-Desmethyl Naproxen
CAS:Controlled Product<p>Applications A metabolite of Naproxen.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rettie, A., et al.: Chem. Res. Toxicol., 5, 54 (1992), Tracy, T., et al.: Biochem. Pharmacol., 52, 1305 (1996), Bonnabry, P., et al.: Eur. J. Clin. Pharmacol., 49, 305 (1996), Rao, S., et al.: J. Med. Chem., 43, 2789 (2000), Hutzler, J., et al.: Drug Metab. Dispos., 29, 1029 (2001),<br></p>Formula:C13H12O3Color and Shape:NeatMolecular weight:216.23Gefitinib
CAS:Controlled ProductFormula:C22H24ClFN4O3Color and Shape:White SolidMolecular weight:446.902-(3-methoxyphenyl)-8-methylquinoline-4-carboxylic acid
CAS:Purity:95.0%Molecular weight:293.32199096679691-(4-Fluorophenyl)-4-(4-(pyridin-2-yl)piperazin-1-yl)butan-1-one
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:327.403015136718756-Methoxy-2-naphthoic Acid
CAS:Controlled Product<p>Impurity Naproxen USP Related Compound A<br>Applications An impurity of Naproxen (N377525) with bactericidal and fungicidal activity. A metabolite of Nabumetone (N200500). Naproxen USP Related Compound A.<br>References Khorana, M.L. et al.: J. Pharmac. Sci., 56, 993 (1967); Ray, J.E. et al.: J. Chrom. Biomed. Appl., 336, 234 (1984);<br></p>Formula:C12H10O3Color and Shape:Off-WhiteMolecular weight:202.211-epi-Darunavir
CAS:Controlled Product<p>Applications Stereoisomer to Darunavir (D193500), a second generation HIV-1-protease inhibitor; structurally similar to amprenavir. Antiviral. It is a COVID19-related research product.<br>References Koh, Y., et al.: Antimicrob. Agents Chemother., 47, 3123 (2003), Arasteh, K., et al.: AIDS, 19, 943 (2005), Surleraux, D.L.N.G., et al.: J. Med. Chem., 48, 1813 (2005),<br></p>Formula:C27H37N3O7SColor and Shape:White To Off-WhiteMolecular weight:547.661-piperazine-1-yl-isoquinoline
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:213.28399658203125Methyl 4-(((4-(pyridin-3-yl)pyrimidin-2-yl)amino)methyl)benzoate
CAS:Purity:95+%Molecular weight:320.351989746093752-Methyl-6-trifluoromethyl-nicotinic acid methyl ester
CAS:Purity:95.0%Color and Shape:LiquidMolecular weight:219.16299438476562Delamanid
CAS:<p>Stability Hygroscopic<br>Applications Delamanid is a novel anti-tuberculosis medication that inhibits mycolic acid synthesis and shows potent in vitro and in vivo activity against drug-resistant strains of Mycobacterium tuberculosis.<br>References Gler, M.T., et al.: New Engl. J. Med., 366, 2151 (2012); Skripconoka, V., et al.: Eur. Respir. J., 41, 1393 (2012); Diacon, A.H., et al.: Int. J. Tuberc. Lung D., 15, 949 (2011); Zhang, Q., et al.: Cell Biochem. Biophys., 67, 957 (2013)<br></p>Formula:C25H25F3N4O6Color and Shape:NeatMolecular weight:534.482-(2-Isopropylamino-thiazol-4-yl)-7-methoxy-quinolin-4-ol
CAS:Purity:97.0%Molecular weight:315.39001464843753,5-Dichloro-4-(difluoromethyl)pyridine
CAS:Formula:C6H3Cl2F2NPurity:95.0%Color and Shape:LiquidMolecular weight:197.994-Methyl-1-(3-methyl-2-pyridinyl)-2-phenylpiperazine
CAS:<p>Applications 4-Methyl-1-(3-methyl-2-pyridinyl)-2-phenylpiperazine is an impurity of Mirtazapine (M365000). Mirtazapine impurity E.<br>References De Boer, T., et al.: Neuropharmacology, 27, 399 (1988), Wynia, G., et al.: J. Chromatography, A 773, 339 (1997),<br></p>Formula:C17H21N3Color and Shape:NeatMolecular weight:267.37Hydroxynorketamine-d6 Hydrochloride
CAS:Controlled Product<p>Applications Hydroxynorketamine-d6 Hydrochloride, is labelled Hydroxynorketamine (H949680, HCl salt), a metabolite of Ketamine (K165300, HCl salt) which is a medication used mainly for starting and maintaining anesthesia.<br>References Adams, J., et al.: Biomed. Mass Spec., 11, 527 (1981); Sass, W.C., et al.: Anal. Profiles Drug Subs., 6, 297 (1977); Reich, D.L., et al.: Can. J. Anaesth., 36, 186 (1989)<br></p>Formula:C12H8D6ClNO2•HClColor and Shape:NeatMolecular weight:282.2Morpholine-4-carbothioic acid amide
CAS:Formula:C5H10N2OSPurity:97%Color and Shape:SolidMolecular weight:146.217-chloro-4-methyl-N-(pyridin-2-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Purity:95.0%Molecular weight:289.77999877929696-Hydroxy Ondansetron
CAS:<p>Applications A metabolite of Ondansetron.<br>References Colthup, P., et al.: J. Pharm. Sci., 80, 868 (1991), Miyauchi, S., et al.: Pharm. Res.,10, 434 (1993), Ekins, S., et al.: Drug Metab. Dispos., 23, 1274 (1995), Worboys, P., et al.: Xenobiotica, 26, 897 (1996),<br></p>Formula:C18H19N3O2Color and Shape:Off-White To Light BrownMolecular weight:309.362C-Desmethyl Metoprolol
CAS:Controlled Product<p>Impurity Metoprolol EP Impurity A<br>Applications C-Desmethyl Metoprolol (Metoprolol EP Impurity A) is a new byproduct detected in Metoprolol tartrate. Metoprolol impurity.<br>References Erickson, M., et al.: J. Pharma. Biomed. Analysis, 13, 567 (1995), Phinney, K., et al.: Chirality, 15, 287 (2003), Zheng, J., et al.: Anal. Chem., 78, 1535 (2006),<br></p>Formula:C14H23NO3Color and Shape:NeatMolecular weight:253.341-[3-Chloro-5-(trifluoromethyl)pyrid-2-yl]-1,4-diazepane
CAS:Purity:98.0%Color and Shape:LiquidMolecular weight:279.690002441406252-(3-Bromo-5-chlorophenyl)-4,6-diphenyl-1,3,5-triazine
CAS:Purity:97%Molecular weight:422.70999145507812-Amino-4-(4-cyclohexyl-phenyl)-thiophene-3-carboxylic acid methyl ester
CAS:Formula:C18H21NO2SPurity:97%Color and Shape:SolidMolecular weight:315.43
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