Quinazoline and Quinoline Derivatives
Quinazolines and quinolines are nitrogen-containing heterocyclic compounds with aromatic structures that play a key role in the synthesis of drugs with anticancer, antimicrobial, and anti-inflammatory activity. Their derivatives feature structural modifications that optimise bioavailability and selectivity, enabling the development of new active ingredients for various therapeutic applications. These compounds are used in the manufacture of APIs for the treatment of cancer, infections, neurodegenerative diseases, and cardiovascular conditions. Additionally, quinazoline and quinoline derivatives are essential in the research of enzyme inhibitors and the design of innovative bioactive molecules.
At CymitQuimica, we offer high-purity quinazoline and quinoline derivatives for applications in chemical synthesis, pharmaceutical development, and biotechnology.
Found 65644 products of "Quinazoline and Quinoline Derivatives"
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Iprodione
CAS:<p>Applications Fungicide. Iprodione is also used in cannabis testing kits as a component of pesticide mixes (P698240).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lacroix, L., et al.: Phytiatr.-Phytopharm., 23, 165 (1974), Brenneman, T.B., et al.: Plant Dis., 71, 546 (1987),<br></p>Formula:C13H13Cl2N3O3Color and Shape:NeatMolecular weight:330.17N-Desmethyl Clozapine-d8
CAS:Controlled Product<p>Applications A major labelled metabolite of clozapine. A potent and selective 5-HT2C serotonin receptor antogonist.<br>References Kuoppamaki, M. et al.: Eur. J. Pharm. Mol. Pharm. Sect., 245, 179 (1993), Olessen, O.V., et al.: J. Chromatog., 622, 39 (1993), Pirmohamed, M., et al.: J. Pharmacol. Exp. Ther., 272, 984 (1995)<br></p>Formula:C172H8H9ClN4Color and Shape:Light YellowMolecular weight:320.854-(3-(Difluoromethyl)-5-(3-fluoro-4-methoxyphenyl)-1H-pyrazol-1-yl)benzenesulfonamide
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:397.3699951171875N-Nitrosodiethylamine (1 mg/mL in Methanol)
CAS:Formula:C4H10N2OColor and Shape:Single SolutionMolecular weight:102.143-Aminopiperidine-2,6-dione Hydrochloride
CAS:Controlled Product<p>Applications 3-Aminopiperidine-2,6-dione hydrochloride is a reagent for preparing lenalidomide that can induce ubiquitination and degradation of CK1α in del(5q) MDS. It can also be used to prepare phthalimide conjugates that can promote ligand-dependent target protein degradation.<br>References Kronke, J., et al.: Nature 523, 183 (2015); Liu C., et al.: Faming Zhuanli Shenqing CN 105348257 A 20160224 (2016); Rao, R., et al. : PCT Int. Appl. WO 2016024286 A2 20160218 (2016)<br></p>Formula:C5H8N2O2·ClHColor and Shape:Off-WhiteMolecular weight:164.5907-chloro-4-methoxy-N-(pyridin-4-ylmethyl)benzo[d]thiazol-2-amine
CAS:Purity:95.0%Molecular weight:305.77999877929692-(4-Methyl-1H-pyrazol-1-yl)ethanol
CAS:Formula:C6H10N2OPurity:95.0%Color and Shape:LiquidMolecular weight:126.1594-(4-Fluorophenyl)-1-methyl-1,2,3,6-tetrahydropyridine Hydrochloride
CAS:Controlled Product<p>Impurity Paroxetine EP Impurity G<br>Applications 4-(4-Fluorophenyl)-1-methyl-1,2,3,6-tetrahydropyridine Hydrochloride (Paroxetine EP Impurity G) is the active metabolite of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) (M325910), N-Methyl-4-phenylpyridinium (MPP+), selectively destroys the dopaminergic neurons and induces the symptoms of Parkinson's disease.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gerlach, M., et al.: Eur. J. Pharmacol., 208, 273 (1991), Tipton, K., et al.: J. Neurochem., 61, 1191 (1993), Wimalasena, D., et al.: J. Biol. Chem., 279, 15298 (2004),<br></p>Formula:C12H14FN·ClHColor and Shape:Light YellowMolecular weight:227.714'-Methoxyacetophenone
CAS:Controlled ProductFormula:C9H10O2Color and Shape:NeatMolecular weight:150.17Quizalofop-p-tefuryl
CAS:Formula:C22H21ClN2O5Color and Shape:Off-White To Light YellowMolecular weight:428.86552-(2,3,4-Trichlorophenyl)quinoline-4-carboxylic acid
CAS:Purity:97%Molecular weight:352.6000061035156Descarboxyl Levofloxacin
CAS:Controlled Product<p>Impurity Levofloxacin Descarboxy Impurity<br>Applications A degradation product of Levofloxacin (L360000).<br>References Wong, F., et al.: J. Pharm. Biomed. Anal., 15, 765 (1997), Singh, G., et al.: Pharmazie, 43, 134 (1988), Radi, A., et al.: Talanta, 58, 319 (2002),<br></p>Formula:C17H20FN3O2Color and Shape:Off-White To Light YellowMolecular weight:317.36Levetiracetam-d3 (contains d0)
CAS:Controlled Product<p>Applications The labelled (S)-enantiomer of Etiracetam (E932970) and the ethyl analog of Piracetam (P500800). Used as an anticonvulsant.<br>References Gower, A.J., et al.: Eur. J. Pharmacol., 222, 193 (1992), Kasteleijn-Noist Trenite, D.G.A., et al.: Epilepsy Res., 25, 225 (1996), Patsalos, P.N., et al.: Pharmacol. Ther., 85, 77 (2000),<br></p>Formula:C8H11D3N2O2Color and Shape:NeatMolecular weight:170.21N-Nitrosoephedrine-D3
CAS:Controlled ProductFormula:C10D3H11N2O2Color and Shape:White To Off-WhiteMolecular weight:197.2494-(4,6-Bis(2,4-dimethylphenyl)-1,3,5-triazin-2-yl)benzene-1,3-diol
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:397.4779968261719N-(4-Pyridin-2-yl-thiazol-2-yl)benzene-1,4-diamine
CAS:Color and Shape:SolidMolecular weight:268.3399963378906Tert-Butyl (R)-(1-(3-(4-Ethoxyphenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)ethyl)carbamate
CAS:Purity:95%Molecular weight:409.48599243164062-(Aminomethyl)-1-ethylpyrrolidine
CAS:Controlled ProductFormula:C7H16N2Color and Shape:Colourless To Light YellowMolecular weight:128.22rac 1-Chloro-3-[4-(2-methoxyethyl)phenoxy]-2-propanol
CAS:Controlled Product<p>Impurity Metoprolol USP Related Compound B<br>Applications An intermediate for the synthesis of β-chlorohydrins and β-chloroamines. An impurity found in metoprolol. Metroprolol USP Related Compound B.<br>References Moore, R., et al.: Marine Natural Products, 1, 43 (1978),<br></p>Formula:C12H17ClO3Color and Shape:ColourlessMolecular weight:244.71Anagliptin
CAS:Controlled Product<p>Applications Anagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that suppresses proliferation of vascular smooth muscles and monocyte inflammatory reaction. It also attenuates atherosclerosis in male apolipoprotein E-deficient mice.<br>References Ervinna, N., et al.: Endocrinology, 154, 1260 (2013); Furuta, S., et al.: Eur. J. Drug Metab. Ph., 38, 87 (2013)<br></p>Formula:C19H25N7O2Color and Shape:NeatMolecular weight:383.45rac-cis-N-Desmethyl Sertraline-d4 Hydrochloride
CAS:Controlled Product<p>Applications A labelled metabolite of Sertraline. N-Desmethyl Sertraline is significantly less active analogue as compared to the methylated compound, Sertraline.<br>References Welch, W.M., et al.: J. Med. Chem. 27, 1508 (1984)<br></p>Formula:C16H12D4Cl3NColor and Shape:NeatMolecular weight:332.69Dasatinib Dimeric Impurity
CAS:Controlled ProductFormula:C36H34Cl2N12O2S2Color and Shape:White To BeigeMolecular weight:801.77(S)-2-Hydroxy-3-methoxy-3,3-diphenylpropionic Acid
CAS:Controlled Product<p>Impurity Ambrisentan Hydroxy Acid Impurity<br>Applications (S)-2-Hydroxy-3-methoxy-3,3-diphenylpropionic Acid is used in analytical studies for chiral discrimination of α-functionalized acids. Ambrisentan Hydroxy Acid Impurity<br>References Jain, N., et al.: Tetrahedron, 70, 4343 (2014)<br></p>Formula:C16H16O4Color and Shape:NeatMolecular weight:272.306-Hydroxy-3,4-dihydro-1H-quinoline-2-one
CAS:Controlled Product<p>Impurity Cilostazol USP Related Compound A<br>Applications A metabolite of Cilostazole.<br>References Gitto, R., et al.: J. Med. Chem., 46, 3758 (2003), Xie, Z., et al.: Bioorg. Med. Chem. Lett., 15, 4803 (2005),<br></p>Formula:C9H9NO2Color and Shape:NeatMolecular weight:163.172-Nitrobenzaldehyde
CAS:<p>Applications 2-Nitrobenzaldehyde is a benzaldhyde with a nitro group substituted in the ortho position. 2-Nitrobenzaldehyde is used in the preparation of dyes and colorants such as Indigo carmine. 2-Nitrobenzaldehyde gas been shown to be a useful photoremovable protecting group as well as in the preparation of more effective ones such as o-Nitrophenylethylene glycol.<br>References Gravel, D. et al.: Can. J. Chem., 61, 400 (1983); Sebej, P. et al.: J. Org. Chem., 74, 8647 (2009); Das, A. et al.: J. Ind. Che,. Soc., 49, 993 (1972);<br></p>Formula:C7H5NO3Color and Shape:NeatMolecular weight:151.124-Chloro-2-methyl-5-(thiophen-2-yl)thieno[2,3-d]pyrimidine
CAS:Purity:95%Molecular weight:266.7600097656254-Hydroxy Moxonidine
CAS:Controlled ProductFormula:C9H13N5O2Color and Shape:NeatMolecular weight:223.23KAD-1229 Calcium Hydrate
CAS:Controlled ProductFormula:C19H24NO3·Ca·2H2OColor and Shape:NeatMolecular weight:704.91Defluoro Levofloxacin
CAS:<p>Impurity Levofloxacin USP Related Compound F<br>Applications Nonfluorinated analog of Levofloxacin (L360000). Levofloxacin USP Related Compound F.<br>References Koga, H., et al.: J. Med. Chem., 23, 1358 (1980), Fujita, M., et al.: Chem. Pharm. Bull., 44, 987 (1996), Graul, A., et al.: Drugs Future, 24, 1324 (1999), Takahata, M., et al.: Antimicrob. Agents Chemother., 43, 1077 (1999),<br></p>Formula:C18H21N3O4Color and Shape:Off-WhiteMolecular weight:343.38Salbutamol Glyoxal Impurity
Controlled Product<p>Stability Hygroscopic<br>Applications Salbutamol Glyoxal Impurity that is synthesized from C369215 (3-Chloromethyl-4-hydroxyacetophenone).<br></p>Formula:C9H10O5Color and Shape:Off White SolidMolecular weight:198.175,5-Diphenyl Hydantoin Sodium
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications 5,5-Diphenyl Hydantoin Sodium salt reduces incidence of grand mal seizures; appears to stabilize excitable membranes perhaps through effects on Na+, K+, and Ca2+ channels.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Faucette, S., et al.: J. Pharmacol. Exp. Ther., 320, 72 (2007), Guo, D., et al.: J. Biol. Chem., 282, 36766 (2007), Merrell, M., et al.: Drug Metab. Dispos., 36, 1716 (2008),<br></p>Formula:C15H11N2O2·NaColor and Shape:NeatMolecular weight:274.25N-Demethyl Ivabradine Hydrochloride
CAS:Controlled ProductFormula:C26H34N2O5·ClHColor and Shape:NeatMolecular weight:491.02[5-(4-Thiophen-2-yl-phenyl)-[1,3,4]oxadiazol-2-ylmethyl]-carbamic acid tert-butyl ester
Purity:95.0%Molecular weight:357.42999267578125Gabapentin-d6 Hydrochloride
CAS:Controlled Product<p>Applications Gabapentin Hydrochloride is a salt analogue of Gabapentin-d6 (G117253), a labelled amino acid structurally related to γ-Aminobutyric Acid (GABA), designed to cross the blood brain barrier. Used as an anticonvulsant.<br>References Vollmer, K.O. et al.: Arzneim.-Forsch., 36, 830 (1986); Saletu, B., et al.: Int. J. Clin. Pharmacol. Ther. Toxicol., 24, 362 (1986)<br></p>Formula:C9H11D6NO2·HClColor and Shape:NeatMolecular weight:213.73Deferiprone-d3 3-O-β-D-Glucuronide Sodium Salt
CAS:Controlled Product<p>Stability Very Hygroscopic<br>Applications A labelled metabolite of Deferiprone (D474000).<br>References Choudhury, R., et al.: Drug Metab. Dispos., 23, 314 (1995);<br></p>Formula:C13H13D3NNaO8Color and Shape:Off-White To Light BeigeMolecular weight:340.28D-Tryptophan Methyl Ester Hydrochloride
CAS:Controlled Product<p>Applications Intermediate for the synthesis of Tryptophan derivatives.<br>References Deveau, A., et al.: Bioorg. Med. Chem. Lett., 18, 3522 (2008),<br></p>Formula:C12H14N2O2·ClHColor and Shape:White To Off-WhiteMolecular weight:254.714,5-dimethyl-N-(pyridin-2-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Purity:95.0%Molecular weight:269.3699951171875
![1,3-Bis[4-(2-pyridyl)-2-thiazolyl]benzene](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF098184.webp&w=3840&q=75)
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![rac 1-Chloro-3-[4-(2-methoxyethyl)phenoxy]-2-propanol](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FC367980.webp&w=3840&q=75)
![4-Chloro-2-methyl-5-(thiophen-2-yl)thieno[2,3-d]pyrimidine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF643420.webp&w=3840&q=75)
![[5-(4-Thiophen-2-yl-phenyl)-[1,3,4]oxadiazol-2-ylmethyl]-carbamic acid tert-butyl ester](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb-webp%2FF545625.webp&w=3840&q=75)
