Steroids and Derivatives
Steroids are organic compounds with a structure of four fused rings, known as the steroid nucleus. This core can be linked to various functional groups that modify their properties and biological functions. Steroids play a key role in regulating metabolic and hormonal processes. They are used in medicine to treat inflammatory disorders, autoimmune diseases, and hormonal imbalances. Additionally, some steroid derivatives have potent anti-inflammatory properties, such as corticosteroids. In specific therapies, they are used to reduce inflammation and manage pain in various diseases.
At CymitQuimica, we offer a variety of steroids and their derivatives for pharmaceutical research and development.
Found 4948 products of "Steroids and Derivatives"
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Betamethasone-d5
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Glucocorticoid.<br>References Ferrante, M.G., et al.: Anal. Profiles Drug Subs., 6, 43 (1977), Li, A., et al.: Chem. Biol. Interact., 142, 7 (2002), Cruz-Monteagudo, M., et al.: Eur. J. Med. Chem., 40, 1030 (2005), Rothfuss, A., et al.: Chem. Res. Toxicol., 19, 1313 (2006),<br></p>Formula:C22H24D5FO5Color and Shape:Off-White To Light YellowMolecular weight:397.49Ethynyl Estradiol-2,4,16,16-d4
CAS:Controlled Product<p>Applications Isotope labelled Ethynyl Estradiol (E685100), an oral contraceptive (1), is a synthetic steroid with high oral estrogenic potency. Used in estrogen replacement therapy (2). This compound is a contaminant of emerging concern (CECs). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References 1. Koetsawang, S. et al.: Contraception. 1982 March:25(3) p231-2412. Cuttler, L. et al.: J. Endocrinol. Metab. 1985 Jun;60(6):1087-92.<br></p>Formula:C202H4H20O2Color and Shape:White To Light YellowMolecular weight:300.43Di-Norbudesonide(Mixture of Diastereomers)
CAS:Controlled Product<p>Impurity Budesonide EP Impurity B<br>Applications Di-Norbudesonide (Budesonide EP Impurity B) is an impurity of Budesonide (B689490), an antiinflammatory agent.<br></p>Formula:C23H30O6Color and Shape:NeatMolecular weight:402.48Estradiol 17-Valerate
CAS:Controlled Product<p>Applications Estradiol (E888000) derivative. An estrogen.<br>References Salole, E.G., et al.: Anal. Profiles Drug Subs., 15, 283 (1986), Lievertz, R.W., et al.: Am. J. Obstet. Gynecol., 156, 1289 (1987),<br></p>Formula:C23H32O3Color and Shape:White To Off-WhiteMolecular weight:356.506β-Hydroxy-11-deoxycortisol
CAS:Controlled Product<p>Applications 6β-Hydroxy-11-deoxycortisol is a corticosteroid which is a metabolite of Cortisol (H714615), a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. Cortisol is released in response to stress and a low level of blood glucocorticoids.<br>References Vigore, L., et al.: Cancer Ther., 6, 699 (2008), Puurunen, J., et al.: J. Clin. Endocrinol. Metab., 94, 1973 (2009), Lemos, D., et al.: J. Endocrinol., 201, 275 (2009), Chen, S., et al.: Am. J. Physiol., 296 (2009),<br></p>Formula:C21H30O5Color and Shape:NeatMolecular weight:362.464-Hydroxyestradiol 4-O-β-D-Glucuronide Sodium Salt
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications 4-Hydroxyestradiol 4-O-β-D-Glucuronide Sodium Salt, is a glucuronide derivative of 4-Hydroxy-17β-estradiol (H941895); a metabolite of Estradiol (E888000) which is the major estrogen secreted by the premenopausal ovary.<br>References Bucala, R., et al.: J. Clin. Endocrinol. Metab., 60, 841 (1985); Telang, N., et al.: Anticancer Res., et al.: 11, 1021 (1991); Seeger, H., et al.: Med. Sci. Res., 26, 481 (1998); Bolton, J., et al.: Chem. Res. Toxicol., 13, 135 (2000); Salole, E.G., et al.: Anal. Profiles Drug Subs., 15, 283 (1986); Lievertz, R.W., et al.: Am. J. Obstet. Gynecol., 156, 1289 (1987)<br></p>Formula:C24H32O9•xNaColor and Shape:NeatMolecular weight:464.51(-)-Estra-4,9-diene-3,17-dione
CAS:Controlled Product<p>Applications A potential metabolite of STS 557 (Dienogest)(D441870). A steroid with antiglucocorticoid activity.<br>References Kloosterboer, H., et al.: J. Steroid Biochem., 31, 567 (1988),<br></p>Formula:C18H22O2Color and Shape:NeatMolecular weight:270.37E,E-Dienestrol-d6
Controlled ProductFormula:C18H12D6O2Color and Shape:Light Beige To BrownMolecular weight:272.37Norgestrel-d6 (Major)
CAS:Controlled Product<p>Applications Labelled Norgestrel. It is an excellent progestational and ovulation inhibiting steroid. The bioactive enantiomer is levorotatory. Progestogen; oral contraceptive.<br>References Sopirak, A.M., et al.: Anal. Profiles Drug Subs., 4, 294 (1975), Dunson, T.R., et al.: Contraception, 48, 109 (1993),<br></p>Formula:C21H22D6O2Color and Shape:White To Light YellowMolecular weight:318.49Estrone
CAS:Controlled Product<p>Impurity Estradiol EP Impurity A/ Ethinylestradiol EP Impurity C<br>Applications Estrone is a metabolite of 17β-Estradiol (E888000). During the metabolism, it is in rapid equilibrium with Estriol (E888960) and 17β-Estradiol (E888000) (1). Causes the feminization of male fish at human and animal waste sites (2).This compound is a contaminant of emerging concern (CECs). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br>References 1. Both, D. et al.: Anal. Prof. Drug Subst. 1983 12 pp135-1892. Goodman-Gruen, D. et al.: J. Clin. Endocrinol. Metab. 1996 Aug;81(8):2999-3003.<br></p>Formula:C18H22O2Color and Shape:White To Off-WhiteMolecular weight:270.37Limaprost-d3 (>90%)
CAS:Controlled Product<p>Applications Labelled Limaprost (L461500). Limaprost is an analog of Prostaglandin E1 with structural modifications intended to give it a prolonged half-life and greater potency. Limaprost is used as an antianginal.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Tsuboi, T., et al.: Arch. Int. Pharmacodyn., 247, 89 (1980), Adaikan, P.G., et al.: Prostaglandins Med., 6, 449 (1981), Kottegoda, S.R., et al.: Prostaglandins Leukotrienes Med., 8, 343 (1982), Ishizaki, T., et al.: Chest, 85, 382 (1984),<br></p>Formula:C22H33D3O5Purity:>90%Color and Shape:NeatMolecular weight:383.54Formestane
CAS:Controlled Product<p>Applications An antitumor drug. An aromatase inhibitor.<br>References Brodie, A.M. and Njar, V.C.: Steroids, 65, 171 (2000), Lonning, P.E., et al.: J. Steroid Biochem, 77, 39 (2001)<br></p>Formula:C19H26O3Color and Shape:NeatMolecular weight:302.41Cortisol-9,11,12,12-d4
CAS:Controlled Product<p>Applications Labelled Cortisol (H714615). Cortisol, or Hydrocortisone, is a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism.<br>References Hechter, O., et al.: Arch. Biochem. Biophys., 25, 457 (1950), Colingsworth, D.R., et al.: J. Biol. Chem., 203, 807 (1953), Florey, K., et al.: Anal. Profiles Drug Subs., 12, 277 (1983),<br></p>Formula:C212H4H26O5Color and Shape:Off-WhiteMolecular weight:366.486β-Hydroxy Norethindrone Acetate
CAS:Controlled Product<p>Impurity Norethindrone Acetate EP Impurity F<br>Applications 6β-Hydroxy Norethindrone Acetate (Norethindrone Acetate EP Impurity F) is an oxidative product of the drug Norethindrone (N676000). Norethindrone impurity.<br>References Reif, V., et al.: Pharmaceutical Res., 4, 54 (1987), Rao, P., et al.: Steroids, 59, 621 (1994),<br></p>Formula:C22H28O4Color and Shape:Off-WhiteMolecular weight:356.461(10)-Dehydro-4(5)-dihydro D-(-)-Norgestrel
Controlled Product<p>Applications Norgestrel (N689500) impurity.<br></p>Formula:C21H28O2Color and Shape:NeatMolecular weight:312.45Androst-4-ene-3,6,17-trione
CAS:Controlled Product<p>Applications An aromatase inhibitor.<br>References Aello, A., et al.: J. Nat. Prod., 54, 281 (1991), Salaja, B.A., et al.: Steroids, 59, 330 (1994), Hunter, A.C., et al.: J. Steroid Biochem. Mol. Biol., 87, 301 (2003),<br></p>Formula:C19H24O3Color and Shape:NeatMolecular weight:300.39(3α)-Allopregnanolone-d5
CAS:Controlled Product<p>Applications Labelled (3α)-Allopregnanolone. (3α)-Allopregnanolone acts as a GABAA receptor positive allosteric modulator. (3α)-Allopregnanolone is a metabolite of Progesterone (P755900). (3α)-Allopregnanolone is a neuroactive steroid present in the blood and also the brain.<br>References Puja, G. et al.: Neuron, 4, 759 (1990); Belelli, D. et ael. Neurosteroid, 6, 565 (2006); Viapiano, M. et al.: Neurochem. Res., 23, 155 (1998);<br></p>Formula:C21H29D5O2Color and Shape:NeatMolecular weight:323.52Betamethasone 9,11-Epoxide 17-Propionate
CAS:Controlled Product<p>Impurity Betamethasone Dipropionate EP Impurity U<br>Applications Betamethasone 9,11-Epoxide 17-Propionate (Betamethasone Dipropionate EP Impurity U) is an impurity of Betamethasone (B327000), an antiinflammatory agent.<br></p>Formula:C25H32O6Color and Shape:NeatMolecular weight:428.52
