CAS 124-94-7
:Triamcinolone
Description:
Triamcinolone is a synthetic corticosteroid with anti-inflammatory and immunosuppressive properties, commonly used in the treatment of various conditions such as allergies, asthma, and autoimmune disorders. It is characterized by its ability to inhibit the release of inflammatory mediators and modulate immune responses. The chemical structure of triamcinolone includes a steroid backbone, which contributes to its biological activity and pharmacokinetics. It is typically administered via topical, oral, or injectable routes, depending on the condition being treated. Triamcinolone is known for its relatively high potency compared to other corticosteroids, and it can be formulated in various forms, including creams, ointments, and injectable suspensions. Its use may be associated with side effects, particularly with long-term use, such as adrenal suppression, weight gain, and increased risk of infections. As with any medication, it is essential to use triamcinolone under medical supervision to manage potential risks and benefits effectively.
Formula:C21H27FO6
InChI:InChI=1S/C21H27FO6/c1-18-6-5-12(24)7-11(18)3-4-13-14-8-15(25)21(28,17(27)10-23)19(14,2)9-16(26)20(13,18)22/h5-7,13-16,23,25-26,28H,3-4,8-10H2,1-2H3/t13-,14-,15+,16-,18-,19-,20-,21-/m0/s1
InChI key:InChIKey=GFNANZIMVAIWHM-OBYCQNJPSA-N
SMILES:F[C@@]12[C@]([C@]3([C@](C)(C[C@@H]1O)[C@](C(CO)=O)(O)[C@H](O)C3)[H])(CCC=4[C@]2(C)C=CC(=O)C4)[H]
Synonyms:- (11Beta,16Alpha)-9-Fluoro-11,16,17,21-Tetrahydroxypregna-1,4-Diene-3,20-Dione
- (11β,16α)-9-Fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
- (4aS,4bR,5S,6aS,6bS,9aR,10aS,10bS)-4b-fluoro-5-hydroxy-6b-(hydroxyacetyl)-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one
- (8Xi,11Beta,14Xi,16Alpha)-9-Fluoro-11,16,17,21-Tetrahydroxypregna-1,4-Diene-3,20-Dione
- 11β,16α,17α,21-Tetrahydroxy-9α-fluoro-1,4-pregnadiene-3,20-dione
- 11β,16α,17α,21-Tetrahydroxy-9α-fluoro-Δ1,4-pregnadiene-3,20-dione
- 11β,16α,17α,21-Tetrahydroxy-9α-fluoro-Δ<sup>1,4</sup>-pregnadiene-3,20-dione
- 9-Alpha-Fluoro-11-Beta,16-Alpha,17-Alpha,21-Tetrahydroxypregna-1,4-Diene-3,20-Dione
- 9-Alpha-Fluoro-16-Alpha-Hydroxyprednisolone
- 9-Fluoro-11,16,17,21-Tetrahydroxypregna-1,4-Diene-3,20-Dione
- 9-Fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
- 9α-Fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
- 9α-Fluoro-11β,16α,17α,21-tetrahydroxypregna-1,4-diene-3,20-dione
- 9α-Fluoro-16α-hydroxyprednisolone
- Acetonide
- Adcortyl
- Aristocort
- Cinolone
- Cl 19823
- Delphicort
- Fluoxiprednisolone
- Fluoxyprednisolone
- Kenacort
- Kenacort AG
- Ledercort
- Mycolog
- Nsc 13397
- Omicilon
- Polcortolon
- Pregna-1,4-diene-3,20-dione, 9-fluoro-11,16,17,21-tetrahydroxy-, (11β,16α)-
- Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,16α,17,21-tetrahydroxy-
- Rodinolone
- Triamcinlon
- Triamcinolon
- Triamcinolone Base
- Triancinolona
- Tricortale
- See more synonyms
Filter by
Purity percentage
0
100
|
0
|
50
|
90
|
95
|
100
- Lower prices
- Higher prices
- Lower purities
- Higher purities
- Faster estimated delivery
Triamcinolone
CAS:Formula:C21H27FO6Purity:>98.0%(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:394.44Triamcinolone
CAS:TriamcinoloneFormula:C21H27FO6Purity:99.5%Color and Shape:White. To. Light YellowMolecular weight:394.17917Triamcinolone
CAS:Halogenated derivatives of adrenal cortical hormonesFormula:C21H27FO6Color and Shape:White Off-White PowderMolecular weight:394.17917Triamcinolone
CAS:Triamcinolone (Aristocort) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.Formula:C21H27FO6Purity:98.66% - 99.60%Color and Shape:White SolidMolecular weight:394.4311β,16α,17α,21-Tetrahydroxy-9α-fluoro-1,4-pregnadiene-3,20-dione
CAS:Formula:C21H27FO6Purity:98%Color and Shape:SolidMolecular weight:394.4339Triamcinolone
CAS:Formula:C21H27FO6Purity:97.5 - 102.5 %Color and Shape:White to off-white crystalline powderMolecular weight:394.43Triamcinolone (Standard)
CAS:Triamcinolone (Standard) is the standard substance of Triamcinolone, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Triamcinolone (Aristocort) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. Upon cell entry, triamcinolone binds to and activates the glucocorticoid receptor, which leads to translocation of the ligand-receptor complex to the nucleus and induces expression of glucocorticoid-responsive genes such as lipocortins. Lipocortins inhibit phospholipase A2, thereby blocking the release of arachidonic acid from membrane phospholipids and preventing the synthesis of prostaglandins and leukotrienes, both mediators of inflammation. In addition, pro-inflammatory cytokine production, including interleukin (IL)-1and IL-6, and the activation of cytotoxic T-lymphocytes is also inhibited. T-cells are prevented from making IL-2 and proliferating. This agent also decreases the number of circulating lymphocytes, induces cell differentiation, and stimulates apoptosis through increasing Ikappa-B expression and curtailing activation of nuclear factor (NF)kappa-B.Formula:C21H27FO6Color and Shape:SolidMolecular weight:394.43GB/T 24800.2-2009 41 Glucocorticoids 100 µg/mL in Methanol
CAS:Controlled Product- 105102-22-5
- 1177-87-3
- 124-94-7
- 13609-67-1
- 14484-47-0
- 1524-88-5
- 2135-17-3
- 2152-44-5
- 25122-46-7
- 25122-57-0
- 3093-35-4
- 33564-31-7
- 356-12-7
- 378-44-9
- 3801-06-7
- 3870-07-3
- 426-13-1
- 4419-39-0
- 50-02-2
- 50-03-3
- 50-04-4
- 50-23-7
- 50-24-8
- 51022-69-6
- 51333-22-3
- 514-36-3
- 53-06-5
- 5534-09-8
- 5593-20-4
- 57524-89-7
- 66734-13-2
- 67-78-7
- 73771-04-7
- 76-25-5
- 80474-14-2
- 83-43-2
- 987-24-6
Color and Shape:MixtureTriamcinolone
CAS:Controlled ProductTriamcinolone is a synthetic corticosteroid that reduces inflammation, suppresses the immune system, and relieves pain. It inhibits the production of cytokines and other inflammatory mediators by binding to specific receptors located in the cells of the immune system. Triamcinolone acetonide is an ester prodrug that is converted to triamcinolone in vivo. This drug has a long-term efficacy because it can be released slowly over time after intravitreal injection. The pharmacokinetic properties of triamcinolone are determined by its lipophilicity and water solubility. Triamcinolone acetonide has been shown to reduce inflammation in chronic arthritis, as well as reducing symptoms of eye disorders such as uveitis or glaucoma. This drug also prevents tumor growth by inhibiting protein synthesis and gene expression at the level of transcription, which leads to decreased cell proliferation or apoptosis.Formula:C21H27FO6Purity:Min. 97 Area-%Color and Shape:White PowderMolecular weight:394.43 g/molTriamcinolone in Acetonitrile
CAS:AcetonitrileFormula:C21H27FO6Color and Shape:SolidMolecular weight:394.4
