Steroids and Derivatives
Steroids are organic compounds with a structure of four fused rings, known as the steroid nucleus. This core can be linked to various functional groups that modify their properties and biological functions. Steroids play a key role in regulating metabolic and hormonal processes. They are used in medicine to treat inflammatory disorders, autoimmune diseases, and hormonal imbalances. Additionally, some steroid derivatives have potent anti-inflammatory properties, such as corticosteroids. In specific therapies, they are used to reduce inflammation and manage pain in various diseases.
At CymitQuimica, we offer a variety of steroids and their derivatives for pharmaceutical research and development.
Found 4964 products of "Steroids and Derivatives"
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4-Hydroxy-17β-estradiol-16,16,17-d5
CAS:Controlled Product<p>Applications A labelled metabolite of Estradiol.<br>References Bucala, R., et al.: J. Clin. Endocrinol. Metab., 60, 841 (1985), Telang, N., et al.: Anticancer Res., et al.: 11, 1021 (1991), Seeger, H., et al.: Med. Sci. Res., 26, 481 (1998), Bolton, J., et al.: Chem. Res. Toxicol., 13, 135 (2000),<br></p>Formula:C182H5H19O3Color and Shape:NeatMolecular weight:293.41Isoflupredone
CAS:Controlled Product<p>Applications Anti-inflammatory.<br>References Buchwald, P., et al.: Steroids, 73, 193 (2008), Holbeck, S., et al.: Mol. Endocrinol., 24, 1287 (2010),<br></p>Formula:C21H27FO5Color and Shape:NeatMolecular weight:378.434-Hydroxy Estrone 1-N7-Guanine
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications 4-Hydroxy Estrone 1-N7-Guanine is an estrogen metabolite formed with DNA which can lead to the mutations that initiate breast, prostate, and other types of cancer. Estrogen-DNA depurinating adducts as biomarkers of cancer risk and their use in cancer detection and prevention.<br>References Chakravarti, D., et al.: Mutat. Res., 456, 17 (2000), Liehr, J., et al.: Endocr. Rev., 21, 4054 (2000), Chakravarti, D., et al.: Oncogene, 20, 7945 (2001), Cavalieri, E., et al.: Chem. Res. Toxicol., 14, 1041 (2002),<br></p>Formula:C23H25N5O4Color and Shape:NeatMolecular weight:435.484-Hydroxy Atorvastatin-d5 Disodium Salt
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications A deuterated metabolite of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br>References Smith, S., et al.: Am. J. Cardiol., 80, 10H (1997), Jacobsen, W., et al.: Drug Metab. Dispos., 28, 1369 (2000), Istvan, E., et al.: Science, 292, 1160 (2001), Tabernero, L., et al.: J. Biol. Chem., 278, 19933 (2003), Bratton, L., et al.: Bioorg. Med. Chem., 15, 5576 (2007),<br></p>Formula:C33H28D5FN2Na2O6Color and Shape:NeatMolecular weight:623.63Cholesterol-d7
CAS:Controlled Product<p>Applications Labelled Cholesterol (C432501). Cholesterol is the principal sterol of the higher animals. Cholesterol was found in all body tissues, especial in the brain, spinal cord, and in animal fats or oils. Cholesterol is the main constituent of gallstones.<br>References Rosin, Z., et al.: Physiol. Chem., 124, 282 (1923), Schoenheimer, et al.: J. Biol. Chem., 105, 355 (1934), Gemant, et al.: Life Sci., 1, 233 (1962), Johnson, K., et al.: 4, 457 (1964),<br></p>Formula:C272H7H39OColor and Shape:NeatMolecular weight:393.70Testosterone β-D-Glucuronide Monosodium Salt
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Metabolite of Testosterone (T155000).<br>References Shibata, N., et al.: Biochem. J., 368, 783 (2002), Sonneveld, E., et al.: Toxicol. Sci., 83, 136 (2005), Schulze, J., et al.: J. Clin. Endocrinol. Metab., 93, 2500 (2008), Sten, T., et al.: Drug Metab. Disposition, 37, 417 (2009),<br></p>Formula:C25H35O8·NaColor and Shape:White To Off-WhiteMolecular weight:486.53Testosterone Enanthate
CAS:Controlled Product<p>Applications Testosterone Enanthate is a derivative of testosterone (T155000), the principal hormone of the testes, produced by the interstitial cells.<br>References Janjic, M.M., et al.: Reproduct. Toxicol., 34, 686 (2012); Lacreuse, A., et al.: Physiol. Behaviour., 106, 229 (2012);<br></p>Formula:C26H40O3Color and Shape:Colourless To Off-WhiteMolecular weight:400.594’-Hydroxy Dutasteride
Controlled Product<p>Applications 4’-Hydroxy Dutasteride is an impurity of Dutasteride (D735000), a dual inhibitor of 5α-reductase isoenzymes type 1 and 2; structurally related to Finasteride (F342000). Dutasteride is used in the treatment of benign prostatic hyperplasia.<br>References Bakshi, R.K., et al.: J. Med. Chem., 38, 3189 (1995), Gisleskog, P.O., et al.: Brit. J. Clin. Pharmacol., 47, 53 (1999), Djavan, B., et al.: Expert Opin. Pharmacother., 6, 311 (2005)<br></p>Formula:C27H30F6N2O3Color and Shape:NeatMolecular weight:544.5317β-Estradiol 3-β-D-Glucuronide
CAS:Controlled Product<p>Applications A metabolite of Estradiol (E888000).<br>References Agasan, A., et al.: J. Immunol. Methods., 177, 251 (1994), Stone, R., et al.: Science, 265, 308 (1994), Tacey, R., et al.: J. Pharm. Biomed. Anal., 2, 1303 (1994),<br></p>Formula:C24H32O8Color and Shape:White To Off-WhiteMolecular weight:448.51(20S)-21-Hydroxy-20-methylpregn-4-en-3-one
CAS:Controlled Product<p>Applications (20S)-21-Hydroxy-20-methylpregn-4-en-3-one is a side chain degradation product of natural sterols. It is also an intermediate in the preparation of follicular fluid-meiosis activating sterol.<br>References Andor, A. et al.: Appl. Environ. Microbiol., 72, 6554 (2006); Blume, T. et al.: Org, Lett., 5, 1837 (2003);<br></p>Formula:C22H34O2Color and Shape:Off-WhiteMolecular weight:330.56α-Methyl Hydrocortisone 21-Hemisuccinate
CAS:<p>Applications An impurity of Methylhydrocortisone.<br>References Wang, C., et al.: Steroids, 66, 811 (2001),<br></p>Formula:C26H36O8Color and Shape:NeatMolecular weight:476.56Testosterone 17-Valerate
CAS:Controlled Product<p>Applications Testosterone ester. Testosterone 17-Valerate has been a useful compound in the development of immunochemical techniques for detection of anabolic androgenic steroids in food supplements.<br>References Ruelle, P., et al.: Int. J. Pharm., 157, 219 (1997), de la Torre, X., et al.: J. Pharm. Biomed. Anal., 24, 645 (2001), Adat, S., et al.: Lett. Drug Des. Discov., 1, 334 (2004), Holubova, B., et al.: Eur. Food Res. Technol., 245, 1011 (2019)<br></p>Formula:C24H36O3Color and Shape:NeatMolecular weight:372.541N-Demethyl Mifepristone
CAS:<p>Applications A metabolite of Mifepristone (M343975).<br>References Ringler, I., et al.: Metabolism, 13, 37 (1964), Gagne, D., et al.: J. Steroid. Biochem., 25, 315 (1986), Jang, G., et al.: Biochem. Pharmacol., 52, 753 (1996), Hild, S., et al.: Hum. Reprod., 15, 822 (2000), Gainer, E., et al.: Steroids, 68, 1005 (2003),<br></p>Formula:C28H33NO2Color and Shape:NeatMolecular weight:415.57Travoprost
CAS:<p>Stability Light Sensitive<br>Applications Travoprost is a selective FP prostaglandin receptor agonist used to treat glaucoma (1,2).<br>References (1) Hellberg, M.R., et al.: J. Ocul. Pharmacol. Ther., 17, 421 (2001) (2) Schuman, J.S., et al.: Am. J. Ophthalmol., 140, 242 (2005)<br></p>Formula:C26H35F3O6Color and Shape:Colourless To BeigeMolecular weight:500.556-Defluoro-6-oxo-fluticasone Propionate
<p>Stability Temperature Sensitive<br>Applications 6-Defluro-6-oxo-fluticasone Propionate is a derivative of Flumethasone (F455000), a glucocorticoid, anti-inflammatory.<br>References Matuszewski, B, et al.: Anal. Chem., 75, 3019 (2003), Fekete, S., et al.: J. Pharm. Biomed. Anal., 49, 64 (2009),<br></p>Formula:C25H30F2O6SColor and Shape:Off-WhiteMolecular weight:496.5625-Hydroxy Vitamin D3 3-Sulfate Sodium Salt (90%)
CAS:Controlled Product<p>Stability Light Sensitive, Temperature Sensitive<br>Applications 25-Hydroxyvitamin D3 3-Sulfate is a metabolite of 24,25-Dihydroxyvitamin D3 and 25-Hydroxyvitamin D3 (C125700).<br>References Higashi, T. et al.: Steroids, 65, 281 (2000); Higashi, T. et al.: Ann. Clin. Biochem., 36, 43 (1999);<br></p>Formula:C27H43NaO5SPurity:90%Color and Shape:NeatMolecular weight:502.68Testosterone-2,2,4,6,6-d5 (1 mg/ml in Acetonitrile)
CAS:Controlled ProductFormula:C192H5H23O2Color and Shape:ColourlessMolecular weight:293.46Prednisolone 21-Methanesulfonate
CAS:Controlled ProductFormula:C22H30O7SColor and Shape:NeatMolecular weight:438.534
