Steroids and Derivatives
Steroids are organic compounds with a structure of four fused rings, known as the steroid nucleus. This core can be linked to various functional groups that modify their properties and biological functions. Steroids play a key role in regulating metabolic and hormonal processes. They are used in medicine to treat inflammatory disorders, autoimmune diseases, and hormonal imbalances. Additionally, some steroid derivatives have potent anti-inflammatory properties, such as corticosteroids. In specific therapies, they are used to reduce inflammation and manage pain in various diseases.
At CymitQuimica, we offer a variety of steroids and their derivatives for pharmaceutical research and development.
Found 4948 products of "Steroids and Derivatives"
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Estra-5(10),9(11)-diene-3,17-dione
CAS:<p>Applications Estra-5(10),9(11)-diene-3,17-dione, can be used as an intermediate for the synthesis of 3-keto-desogestrel.<br>References Wang, R., et al.: Zhongguo Yaowu Huaxue Zazhi, 4, 187 (1994);<br></p>Formula:C18H22O2Color and Shape:NeatMolecular weight:270.36620(R)-Hydroxy Prednisolone
CAS:Controlled Product<p>Applications Prednisolone (P703740) metabolite.<br>References Garg, V., et al.: Biopharm. Drug Disposition, 15, 163 (1994), Adham, N., et al.: Proc. Biochem., 38, 897 (2003),<br></p>Formula:C21H30O5Color and Shape:Off-WhiteMolecular weight:362.46Fulvestrant-d3
CAS:Controlled ProductFormula:C32H44D3F5O3SColor and Shape:White To Off-WhiteMolecular weight:609.79Latanoprost
CAS:<p>Applications Prostaglandin analog, used to treat glaucoma and other degenerative diseases of the eye.<br>References Rhee, D.J., et al.: Clinic. Ophthalmol., 2, 313 (2008), Hernandez, M., et al.: Exp. Eye Res., 86, 798 (2008), Nagata, T., et al.: J. Pharmacol. Sci., 106, 423 (2008), Ikeda, Y., et al.: J. Ocular Pharmacol. Ther., 24, 230 (2008),<br></p>Formula:C26H40O5Color and Shape:Light YellowMolecular weight:432.59Prednival
CAS:Controlled Product<p>Applications Prednival was used in the study of inflammation-inhibiting activity of steroids.<br>References Bodor, N., et al.: J. Med. Chem., 26, 318 (1983); Stouch, T., et al.: J. Med. Chem., 29, 2125 (2986);<br></p>Formula:C26H36O6Color and Shape:NeatMolecular weight:444.567α-Hydroxy-4-cholesten-3-one
CAS:<p>Applications 7α-Hydroxy-4-cholesten-3-one is a metabolite of Cholesterol (C432501).<br>References Connor, W., et al.: J, Clin. Invest., 48, 1363 (1969), Nestel, P., et al.: Metabolism, 24, 189 (1975), Ellegard, L., et al.: Eur. J. Clin. Nutr., 45, 451 (1991), Pedersen, A., et al.: J. Lipid Res., 41, 1901 (2000),<br></p>Formula:C27H44O2Color and Shape:NeatMolecular weight:400.64Dienogest-d8 (major)
CAS:Controlled Product<p>Applications Dienogest-d8 (major) is labelled derivative of 19-Nortestosterone. It is used in combination with estrogen as oral contraceptive.<br>References Hubner, M., et al.: Arzneim.-Forsch., 30, 401 (1980), Spona, J., et al.: Contraception, 56, 185 (1997), Foster, R.H., et al.: Drugs, 56, 825 (1998)<br></p>Formula:C20H17D8NO2Color and Shape:Light YellowMolecular weight:319.47Paricalcitol
CAS:Controlled Product<p>Stability Light Sensitive, Temperature Sensitive<br>Applications Synthetic analog of vitamin D. Antihyperparathyroid.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sidek, H., et al.: Biochim. Biophys. Acta, 801, 26 (1984), Ciftci, M., et al.: J. Pharmacol., 54, 275 (2002),<br></p>Formula:C27H44O3Color and Shape:NeatMolecular weight:416.64(11β,16α)-11-Hydroxy-16-(1-oxobutoxy)-androsta-1,4-diene-3,17-dione
CAS:Formula:C23H30O5Color and Shape:ColourlessMolecular weight:386.48Pregnenolone monosulfate
CAS:<p>Pregnenolone monosulfate (3β-Hydroxy-5-pregnen-20-one monosulfate) is a potent nootropic steroid used in the study of neuroticism and depression.</p>Formula:C21H32O5SPurity:99.46%Color and Shape:SolidMolecular weight:396.54Dexamethasone Valerate
CAS:<p>Impurity Betamethasone Valerate EP Impurity C<br>Stability Hygroscopic<br>Applications Dexamethasone Valerate (Betamethasone Valerate EP Impurity C) is an impurity of Dexamethasone (D298800), which is a glucocorticoid that is used as an anti-inflammatory agent. Dexamethasone regulates T cell survival, growth, and differentiation. Dexamethasone inhibits the induction of nitric oxide synthase.<br>References Wershil, B.K., et al.: Int. Arch. Allergy Immunol., 107, 323 (1995), Riccardi, C., et al.: Cell Death Diff., 6, 1182 (1999), Llanos, S.L. and Roldan, A.: Bio Cell, 23, 29 (1999)<br></p>Formula:C27H37FO6Color and Shape:Off-WhiteMolecular weight:476.5817-epi-Testosterone
CAS:Controlled Product<p>Applications Testosterone and epitestosterone are endogenous steroids that differ in the configuration of the hydroxyl-bearing carbon at C-17. Testosterone is the predominant male sex hormone, whereas the role of epitestosterone is largely unclear. In humans, both androgens are excreted mainly as glucuronide conjugates.<br>References Wudy, S., et al.: Steroids, 66, 759 (2001), Kootstra, P., et al.: Anal. Chim. Acta., 586, 82 (2007), Sten, T., et al.: Drug Metab. Dispos., 37, 417 (2009),<br></p>Formula:C19H28O2Color and Shape:White To Light YellowMolecular weight:288.4217β-Estradiol-d4
CAS:Controlled Product<p>Applications Isotope labelled 17β-Estradiol (E888000), which is the major estrogen (1) secreted by the premenopausal ovary (2).Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br>References 1. Salole, E. et al.: Anal. Profiles Drug Subs. 1986 15, 23 283-3182. Lievertz, R. et al.: Am. J. Obstet. Gynecol. 1987 May;156(5):1289-93.<br></p>Formula:C182H4H20O2Color and Shape:Off-WhiteMolecular weight:276.41Tetrahydrocortisol
CAS:Controlled Product<p>Applications Tetrahydrocortisol is excreted in large amounts in premenopausal patients with early breast cancer. Tetrahydrocortisol has been found to be produced by lymphocytes in both normal and cancer bearing patients however, the concentration of Tetrahydrocortisol has increased in patients with cancer.<br>References Kodama, M., et. al.: J. Natl. Cancer I., 54, 1275 (1975); Klein, A., et. al.: Metabolism, 27, 731 (1978)<br></p>Formula:C21H34O5Color and Shape:Off-WhiteMolecular weight:366.494-Fluoro-α-(2-methyl-1-oxopropyl)-γ-oxo-N,β-diphenyl-benzenebutanamide
CAS:Controlled Product<p>Impurity Atorvastatin Diketo Amide Impurity<br>Applications An Atorvastatin intermediate. Atorvastatin is a selective, competitive HMG-CoA reductase inhibitor. The only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br>References Winters, R., et al.: J. Med. Chem., 36, 1735 (1993), Hagmann, W., et al.: Bioorg. Med. Chem. Lett., 10, 1975 (2000), Istvan, E., et al.: Science, 292, 1160 (2001)<br></p>Formula:C26H24FNO3Color and Shape:White To Off-WhiteMolecular weight:417.472-Methoxy Estrone
CAS:Controlled Product<p>Applications 2-Methoxyestrone is a endogenous estrogen metabolite. 2-Methoxyestrone detection can be used as a breast cancer biomarker and help assess the risk-factors for development of breast cancer.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Franke, A.A. et al.: Ana;. Bioanal. Chem., 401, 1319 (2011); Farlow, D.W. et al.: J. Chrom B Anal. Technol. Biomed Life Sci., 877, 1327 (2009);<br></p>Formula:C19H24O3Color and Shape:NeatMolecular weight:300.39Lasofoxifene
CAS:<p>Applications A next-generation selective estrogen receptor modulator for treating disorders associated with increased bone turnover and osteopenia.<br>References Baumann, R., et al.: Biochem. Pharmacol., 55, 841 (1998), Ammann, P., et al.: Osteoporos Int., 10, 369 (1999), Alexandersen, P., et al.: J. Clin. Endocrinol. Metab., 86, 755 (2001), Bourrin, S., et al.: Bone, 30, 195 (2002), Buzdar, A., et al.: J. Clin. Oncol., 21, 1007 (2003),<br></p>Formula:C28H31NO2Color and Shape:NeatMolecular weight:413.55Betamethasone 11,21-Diacetate
CAS:Controlled Product<p>Impurity Betamethasone Acetate EP Impurity C<br>Applications Betamethasone 11β,21-Diacetate is an impurity of Betamethasone 21-Acetate (B327025); a glucocorticoid steroid with anti-inflammatory and immunosuppressive properties which can be used in treatment of asthma and itching.<br>References Kerns, E., et al.: J. Pharm. Sci., 90, 1838 (2001); Seidler, J., et al.: J. Med. Chem., 46, 4477 (2003); Alsenz, J., et al.: J. Pharm. Sci., 96, 1748 (2007)<br></p>Formula:C26H33FO7Color and Shape:WhiteMolecular weight:476.536-Oxo D-(-)-Norgestrel
CAS:Controlled Product<p>Impurity Levonorgestrel EP Impurity J<br>Applications 6-Oxo D-(-)-Norgestrel (Levonorgestrel EP Impurity J) is an impurity of D-(-)-Norgestrel (N689510).<br></p>Formula:C21H26O3Color and Shape:NeatMolecular weight:326.43Testosterone Sulfate-d3 Triethylamine Salt
CAS:Controlled Product<p>Applications The labelled analogue of a metabolite of Testosterone (T155000). It is a urinary metabolite of Androstenedione (A637550) in patients with Addison's disease and also used as a marker in blood plasma for detection of prostate cancer.<br>References Lokhov, P.G. et al.: Metabolomics, 6, 156 (2010); Bonnaire, Y. et al.: J. Anal. Toxicol., 19, 175 (1995); Tamm, J. et al.: Steroids, 8, 659 (1966);<br></p>Formula:C25H40D3NO5SColor and Shape:Off-WhiteMolecular weight:472.7
