Steroids and Derivatives
Steroids are organic compounds with a structure of four fused rings, known as the steroid nucleus. This core can be linked to various functional groups that modify their properties and biological functions. Steroids play a key role in regulating metabolic and hormonal processes. They are used in medicine to treat inflammatory disorders, autoimmune diseases, and hormonal imbalances. Additionally, some steroid derivatives have potent anti-inflammatory properties, such as corticosteroids. In specific therapies, they are used to reduce inflammation and manage pain in various diseases.
At CymitQuimica, we offer a variety of steroids and their derivatives for pharmaceutical research and development.
Found 4973 products of "Steroids and Derivatives"
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Travoprost
CAS:<p>Stability Light Sensitive<br>Applications Travoprost is a selective FP prostaglandin receptor agonist used to treat glaucoma (1,2).<br>References (1) Hellberg, M.R., et al.: J. Ocul. Pharmacol. Ther., 17, 421 (2001) (2) Schuman, J.S., et al.: Am. J. Ophthalmol., 140, 242 (2005)<br></p>Formula:C26H35F3O6Color and Shape:Colourless To BeigeMolecular weight:500.556-Defluoro-6-oxo-fluticasone Propionate
<p>Stability Temperature Sensitive<br>Applications 6-Defluro-6-oxo-fluticasone Propionate is a derivative of Flumethasone (F455000), a glucocorticoid, anti-inflammatory.<br>References Matuszewski, B, et al.: Anal. Chem., 75, 3019 (2003), Fekete, S., et al.: J. Pharm. Biomed. Anal., 49, 64 (2009),<br></p>Formula:C25H30F2O6SColor and Shape:Off-WhiteMolecular weight:496.5615-Keto Travoprost
CAS:Controlled Product<p>Stability Light Sensitive<br>Applications An impurity of the selective FP prostaglandin receptor agonist Travoprost (T715600) used as an ocularly applied intraocular pressure reducing agent.<br></p>Formula:C26H33F3O6Color and Shape:NeatMolecular weight:498.53Didemethyl Mifepristone
CAS:Controlled Product<p>Applications A metabolite of Mifepristone.<br>References Heikinheimo, O., et al.: J. Steroid Biochem., 26, 279 (1987), Brogden, R., et al.: Drugs, 45, 384 (1993), Shi, Y., et al.: Contraception, 48, 133 (1993), Jang, G., et al.: Biochem. Pharmacol., 52, 753 (1996), Gainer, E., et al.: Steroids, 68, 1005 (2003),<br></p>Formula:C27H31NO2Color and Shape:NeatMolecular weight:401.543,3-Dimethoxyestra-5(10),9(11)-dien-17-one
CAS:<p>Applications 3,3-Dimethoxyestra-5(10),9(11)-dien-17-one, can be used for the synthesis of Trenbolone Acetate (T719080).<br>References Zhang, H., et al.: Fudan Xuebao, Yixueban, 29 (3), 211 (2002);<br></p>Formula:C20H28O3Color and Shape:NeatMolecular weight:316.43Spironolactone-d7 (Major)
CAS:Controlled Product<p>Applications It is a synthetic 17-lactone steroid which is a renal competitive aldosterone antagonist in a class of pharmaceuticals called potassium-sparing diuretics, used primarily to treat ascites in patients with liver disease, low-renin hypertension, hypokalemia, and Conn’s syndrome. A representative lot was 19% d3; 47% d6; 12% d7; 7% d8; 3% d9; 3% d10 and 8% d11.<br>References Sutter, J.L., et al.: Anal. Profiles Drug Subs., 4, 431 (1975),<br></p>Formula:C24H25D7O4SColor and Shape:NeatMolecular weight:423.62Isoflupredone Acetate
CAS:Controlled Product<p>Applications An anti-inflammatory drug used in veterinary medicine. It is a corticosteroid with both glucocorticoid and mineralocorticoid activity and has been shown to increase the frequency of severe hypokalemia in healthy cows.<br>References Coffer, N.Y. et al.: Am. J. Vet. Res., 67, 1244 (2006); Seifi, H.A. et al.: J. Diary Sci., 90, 4181 (2007);<br></p>Formula:C23H29FO6Color and Shape:Off-WhiteMolecular weight:420.47(5a)-Pregnane-3,20-dione
CAS:<p>Applications (5α)-Pregnane-3,20-dione exerts neuroprotective effects in chronic autoimmune encephalomyelitis (EAE). The neuroactivity of the steroid acts as a therapeutic agent for multiple sclerosis.<br>References Caruso, D. et al.: J. Neuroendocrinol., 24, 851 (2012);<br></p>Formula:C21H32O2Color and Shape:Off-WhiteMolecular weight:316.48(22R)-Budesonide
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Budesonide (B689490) epimer R. Budesonide 22R epimer is more active than 22S epimer. Used as an antiinflammatory agent.<br>References Ryrfeldt., A., et a.: J. Steroid Biochem., 10, 317 (1979), Roth, G., et al.: J. Pharm. Sci., 69, 766 (1980), Clissold, S.P., et al.: Drugs, 28, 485 (1984),<br></p>Formula:C25H34O6Color and Shape:NeatMolecular weight:430.53Halcinonide
CAS:Controlled Product<p>Applications Anti-inflammatory (topical).<br>References Kirshbaum, J., et al.: Anal. Profiles Drug Subs., 8, 251 (1979),<br></p>Formula:C24H32ClFO5Color and Shape:NeatMolecular weight:454.96(R)-Ostarine
CAS:Controlled Product<p>Applications The R-enantiomer of nonsteroidal selective androgen receptor modulator (SARM) Ostarine (O703500).<br></p>Formula:C19H14F3N3O3Color and Shape:Light Orange Colour SolidMolecular weight:389.33Cortisol-9,12,12-d3
CAS:Controlled Product<p>Applications Isotope labelled Cortisol (H714615) a topical corticosteroid, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland . Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism.<br>References Vigore, L., et al.: Cancer Biol Ther.. 15. :699 (2014); Puurunen, J. et al.: J. Clin. Endocrinol. Metab., 94, 1973 (2009);<br></p>Formula:C21D3H27O5Color and Shape:NeatMolecular weight:365.486β-Hydroxy Progesterone (Contains up to 20% 17α-Hydroxy Progesterone)
CAS:Formula:C21H30O3Purity:>80%Color and Shape:NeatMolecular weight:330.46Ethyl 3-Oxo-4-aza-5α-androst-1-ene-17β-carboxylate
CAS:Controlled Product<p>Impurity Dutateride EP Impurity C<br>Applications Ethyl 3-Oxo-4-aza-5α-androst-1-ene-17β-carboxylate (Dutateride EP Impurity C) is a compound synthesized in the production of azasteroids. Used in the inhibition of 5α-reductase and of androgen receptor binding, both major effecters in the male hormonal system.<br>References Ramusson, G. et al.: J. Med. Chem., 29, 2298 (1986);<br></p>Formula:C21H31NO3Color and Shape:White To Off-WhiteMolecular weight:345.486-Bromo-betamethasone 17,21-Dipropionate
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications 6-Bromo-Betamethasone 17,21-Dipropionate (Betamethasone Dipropionate EP Impurity H) is an impurity of Betamethasone (B327000), a glucocorticoid used as an anti-inflammatory agent.<br>References Ferrante, M.G., et al.: Anal. Profiles Drug Subs., 6, 43 (1977); Li, A., et al.: Chem. Biol. Interact., 142, 7 (2002); Cruz-Monteagudo, M., et al.: Eur. J. Med. Chem., 40, 1030 (2005)<br></p>Formula:C28H36BrFO7Color and Shape:NeatMolecular weight:583.48Dienogest
CAS:Controlled Product<p>Applications Derivative of 19-Nortestosterone. In combination with estrogen as oral contraceptive. Progestogen.<br>References Hubner, M., et al.: Arzneim.-Forsch., 30, 401 (1980), Spona, J., et al.: Contraception, 56, 185 (1997), Foster, R.H., et al.: Drugs, 56, 825 (1998),<br></p>Formula:C20H25NO2Color and Shape:NeatMolecular weight:311.42Estradiol 17-Propionate
CAS:Controlled Product<p>Applications A 17β-estradiol ester as prodrug of Estradiol (E888000).<br>References Kabasakalian, P., et al.: J. Pharm. Sci., 55, 642 (1966), Marsh, M., et al.: Br. Med. Bull., 48, 426 (1992),<br></p>Formula:C21H28O3Color and Shape:White To Off-WhiteMolecular weight:328.4521-Dehydro Budesonide
CAS:Controlled Product<p>Impurity Budesonide EP Impurity D<br>Stability Hygroscopic<br>Applications 21-Dehydro Budesonide (Budesonide EP Impurity D) is a Budesonide (B689490) impurity.<br>References Backes, S., et al.: Drug Metab. Rev., 34, 157 (2002), Vermeer, H., et al.: Clin. Endocrinol., 59, 49 (2003), Assi, K., et al.: J. Pharm. Biomed. Anal., 41, 325 (2006),<br></p>Formula:C25H32O6Color and Shape:NeatMolecular weight:428.52
