Organic Phosphates and Phosphonates

Applications A metabolite of the anti-tumor drug Ifosfamide (I265000). An impurity of Cyclophosphamide (C988580).
References Gilard, V. et al.: J. Med. Chem., 42, 2542 (1999); Seligman, A.M. et al.: Cancer Chemother. Rep., 59, 233 (1975);

Applications D-Captopril and Captopril analogues are New Delhi metallo-β-lactamase-1 (NDM-1) inhibitors which are used clinically as antidotes for metal poisoning and bacterial infection.
References Ningning; X., et al.: Bioorg. Med. Chem. Lett., 24, 386 (2014); Guo, Y., et al.: Protein Cell, 2, 384 (2011)

Applications 3-(Methylnitrosamino)propionitrile (MNPN) was detected for the 1st time in the saliva of betel quid chewers and is a potent carcinogen.
References Bartsch, H., et al.: Mutat. Res., 250, 103 (1991), Su, T., et al.: Drug Metab. Dispos., 24, 884 (1996), Guengerich, F., et al.: Chem. Res. Toxicol., 14, 611 (2001),

Stability Moisture Sensitive
Applications A cholinesterase inhibitor; a nonsystemic organophosphate insecticide. This compound is a contaminant of emerging concern (CECs). Used as a standard for Pesticide detection.Diazinon is useful in cannabis testing kits as a component of pesticide mixes (P698230).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Gaines, T.B., et al.: Toxicol. Appl. Pharmacol., 14, 515 (1969);