Organic Phosphates and Phosphonates
Organic phosphates are compounds that contain a phosphate group (-PO₄) attached to a carbon atom within an organic structure, typically in combination with alcohols, acids, or amines. These compounds are used in API formulation to enhance the solubility, stability, and bioavailability of active ingredients. Organic phosphates also play a role in controlled drug release and in improving the absorption of certain medications.
Organic phosphonates contain a phosphonate group (-PO₃H₂) in which the phosphorus atom is bonded to a carbon atom and two oxygen groups. These compounds have important pharmacological properties, particularly in enzyme inhibition and biochemical process modulation. Organic phosphonates are used in the production of APIs that target bone metabolism, bacterial infections, or antiviral treatments due to their specific biological effects.
At CymitQuimica, we offer organic phosphates and phosphonates for research in medicinal chemistry, biochemistry, and the development of advanced formulations.
Found 1200 products of "Organic Phosphates and Phosphonates"
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(4S)-4-(Phenylthio)-L-proline Hydrochloride
CAS:<p>Applications (4S)-4-(Phenylthio)-L-proline is an impurity of Zofenopril (Z587000).<br>References Krapcho, J., et al.: J. Med. Chem., 31, 1148 (1988),<br></p>Formula:C11H14ClNO2SColor and Shape:NeatMolecular weight:259.75Butafosfan
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Butafosfan, a component of Catosal, is licensed for the treatment of metabolic disorders or as a tonic in swine. It reduces the stress-induced cortisol (C696302, d4 labelled) response after mixing of unfamiliar pigs. It can also increase milk production in Holstein cows in combination with cyanocobalamin.<br>References De Groot, J., et al.: J. Vet. Pharmacol. Ther., 26, 222 (2003); Pereira, R., et al.: Animal, 7, 1143 (2013)<br></p>Formula:C7H18NO2PColor and Shape:White To Off-WhiteMolecular weight:179.20Triethyl Phosphonoacetate
CAS:Controlled Product<p>Applications Reagent used for Horner-Emmons modification.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hediger, M., et al.: Bioorg. Med. Chem., 12, 4995 (2004), Kim, J., et al.: Nat., 452, 239 (2008),<br></p>Formula:C8H17O5PColor and Shape:ColourlessMolecular weight:224.19Zofenopril Calcium Salt
CAS:<p>Applications Angiotensin-converting enzyme ACE inhibitor. A prodrug that is de-esterified to the active inhibitor, the sulfhydryl group containing metabolite, Zofenoprilat.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gorren, A., et al.: Biochem. J., 331, 801 (1998), Subissi, A., et al.: Cardivascular Drug Reviews, 17, 2 (1999), Marchand, C., et al.: Mol. Pharmacol., 64, 600 (2003), Maurin, C., et al.: J. Med. Chem., 47, 5583 (2004),<br></p>Formula:C22H22NO4S2·CaColor and Shape:NeatMolecular weight:897.17Alendronic Acid-d6 Sodium Salt Hydrate
CAS:Controlled Product<p>Applications Alendronic Acid-d6 Sodium Salt is a labelled salt analogue of Alendronic Acid (A521250), a bisphosphonate used as a bone reabsoption inhibitor.<br>References Wang, X.M., et al.: Clin. J. Dent. Res., 3, 26 (2000); Woo, T., et al.: Best Pract. Res. Clin. Rheumatol., 15, 469 (2001); Benford, H.L., et al.: Bone, 28, 465 (2001)<br></p>Formula:C4H6D6NNaO7P2xH2OColor and Shape:NeatMolecular weight:277.11Amifostine Trihydrate
CAS:Controlled Product<p>Applications Amifostine Trihydrate is a widely used cytoprotective and radio-protective agent.<br>References Adibhatla K.S., et al. Novel method of manufacture of high purity Amifostine trihydrate. Indian Pat. Appl. IN 2005CH01592 A 20080125. Jan 25, 2008<br></p>Formula:C5H15N2O3PS·3H2OColor and Shape:NeatMolecular weight:268.27Ethyl Dihydrogen Phosphate
CAS:Controlled ProductFormula:C2H7O4PColor and Shape:White To BeigeMolecular weight:126.048Difluoromethylenediphosphonic Acid
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications A phosphonic acid derivative for development of biologically active compounds.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ma, Q.F., et al.: Biochemistry, 29, 1412 (1990), Soti, C., et al.: Eur. J. Biochem., 270, 2421 (2003), Barabas, O., et al.: J. Biol. Chem., 279, 42907 (2004),<br></p>Formula:CH4F2O6P2Color and Shape:NeatMolecular weight:211.98Sodium (2R,3R,4S)-2,3,4,6-tetrahydroxy-5-oxohexyl phosphate
CAS:Purity:95.0%Molecular weight:322.004171806Malathion β-Monoacid
CAS:<p>Stability Hygroscopic<br>Applications A major biodegradation product of Malathion (M111000).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kim, Y. et al.: Chemosphere, 60, 1349 (2005); Yoshii, K. et al.: J. Health Sci., 54, 535 (2008); Hayasaka, M. et al.: Jap. J. Forensic Toxicol., 12, 15 (1994);<br></p>Formula:C8H15O6PS2Color and Shape:NeatMolecular weight:302.30(2-Bromoethyl)phosphonic acid
CAS:Purity:95.0%Color and Shape:SolidMolecular weight:188.94500732421875Fenthion
CAS:Controlled Product<p>Stability Moisture Sensitive<br>Applications Fenthion is an organothiophosphate used as an insecticide. Fenthion is also a potent acaricide. Useful in cannabis testing kits as a component of pesticide mixes (P698230).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Pati, B.R. et al.: Plant Soil, 80, 215 (1984); Barros, A.T. et al.: Vet. Parasitol., 96, 243 (2001); Kyriakidis, N.V. et al.: Food Chem., 91, 241 (2005);<br></p>Formula:C10H15O3PS2Color and Shape:Colourless To Light YellowMolecular weight:278.33Carboxyphosphamide
CAS:Controlled Product<p>Applications A metabolite of Cyclophosphamide (CPA) (C988580).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Takamizawa, A., et al.: J. Med. Chem., 18, 376 (1975), Jones, R.J., et al.: J. Hematother., 1, 343 (1992), Biggs, D., et al.: Prog. Clin. Biol. Res., 389, 9 (1994),<br></p>Formula:C7H15Cl2N2O4PColor and Shape:NeatMolecular weight:293.08Phosphoric Acid Potassium
CAS:<p>Stability Hygroscopic<br>Applications Potassium salt of Phosphoric Acid (P359200), used in various chemical processes as a phosphorylating compound. Also used in the preparation of prosthetics and collagen nanocomposites due to the bone-like properties. pH buffer.<br>References Ezhova, Z. et al.: Russ. J. Inorg. Chem., 58, 1177 (2013); Wu, Y. et al.: Asian J. Chem., 25, 5881 (2013);<br></p>Formula:K·H2O4PColor and Shape:WhiteMolecular weight:136.09Cilazapril
CAS:Controlled Product<p>Applications An ACE inhibitor. Hydrolyzed in vivo to the active diacid metabolite (Cilazaprilat). Antihypertensive.<br>References Natoff, I.L., et al.: J. Cardiovasc. Pharmacol., 7, 569 (1985), Szucs, T., et al.: Drugs, 41, Suppl.1, 18 (1991), Pordy, R.C., et al.: Cardiology, 86, 41 (1995),<br></p>Formula:C22H31N3O5Color and Shape:WhiteMolecular weight:417.50
