Organic Phosphates and Phosphonates
Organic phosphates are compounds that contain a phosphate group (-PO₄) attached to a carbon atom within an organic structure, typically in combination with alcohols, acids, or amines. These compounds are used in API formulation to enhance the solubility, stability, and bioavailability of active ingredients. Organic phosphates also play a role in controlled drug release and in improving the absorption of certain medications.
Organic phosphonates contain a phosphonate group (-PO₃H₂) in which the phosphorus atom is bonded to a carbon atom and two oxygen groups. These compounds have important pharmacological properties, particularly in enzyme inhibition and biochemical process modulation. Organic phosphonates are used in the production of APIs that target bone metabolism, bacterial infections, or antiviral treatments due to their specific biological effects.
At CymitQuimica, we offer organic phosphates and phosphonates for research in medicinal chemistry, biochemistry, and the development of advanced formulations.
Found 1190 products of "Organic Phosphates and Phosphonates"
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Amifostine Thiol Dihydrochloride >90%
CAS:<p>Stability Hygroscopic<br>Applications Amifostine Thiol is a metabolite of Amifostine (A576810) which provides normal cells with selective protection against the toxic effects of cancer chemotherapy and radiation treatment.<br>References Satge, J., et al.: Eur. J. Med. Chem., 24, 48 (1989); Geary, R.S., et al.: Biopharm. Drug Dispos., 12, 261 (1991); Brown, D.Q., et al. Pharmacol. Ther., 39, 159 (1988); Capizzi, R.L., et al.: Cancer, 72, 3495 (1993); Treskes, M., et al.: Cancer Chemother. Pharmacol., 33, 93 (1993)<br></p>Formula:C5H14N2S·2ClHPurity:>90%Color and Shape:NeatMolecular weight:207.16Carboxyphosphamide-d4
CAS:Controlled Product<p>Applications A labelled metabolite of Cyclophosphamide (CPA) (C988580).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Takamizawa, A., et al.: J. Med. Chem., 18, 376 (1975), Jones, R.J., et al.: J. Hematother., 1, 343 (1992), Biggs, D., et al.: Prog. Clin. Biol. Res., 389, 9 (1994),<br></p>Formula:C7H11D4Cl2N2O4PColor and Shape:NeatMolecular weight:297.11(R,S)-4-Hydroxy Cyclophosphamide Preparation Kit
CAS:<p>Stability Unstable in Solution<br>Applications A metabolite of Cyclophosphamide.This Kit consists of a vial of the precursor, 4-hydroperoxycyclophosphamide (H714675), and a vial of sodium thiosulfate (S673640). Simply add water to the reducing agent until it is completely dissolved and add this solution to the precursor. This solution has a half-life of approximately 200 minutes at room temperature. Detailed instructions are enclosed.<br>References Peter, G., et al.: Cancer. Chemother. Pharmacol., 3, 181 (1979), Fenselau, C., et al.: Drug Metab. Dispos., 10, 636 (1982), Gamcsik, M., et al.: J. Med. Chem., 33, 1009 (1990), Habib, A., et al.: Biochem. Pharmacol., 50, 429 (1995),<br></p>Formula:C7H15Cl2N2O3PColor and Shape:Off White CrystallineMolecular weight:277.09Malathion α-Monoacid
CAS:Controlled Product<p>Stability Moisture Sensitive<br>Applications A major biodegradation product of Malathion (M111000).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kim, Y. et al.: Chemosphere, 60, 1349 (2005); Yoshii, K. et al.: J. Health Sci., 54, 535 (2008); Hayasaka, M. et al.: Jap. J. Forensic Toxicol., 12, 15 (1994);<br></p>Formula:C8H15O6PS2Color and Shape:NeatMolecular weight:302.3Zoledronic Acid Disodium Salt Tetrahydrate
CAS:Controlled Product<p>Applications A biphosphonate bone resorption inhibitor.<br>References Green, J.R., et al.: J. Bone Min. Res., 9, 745 (1994), Risser, F., et al.: J. Pharm. Biomed. Anal., 15, 1877 (1997), Body, J.J., Cancer, 80, 1699 (1997),<br></p>Formula:C5H8N2O7P2·2Na·4H2OColor and Shape:NeatMolecular weight:388.11Imidazol-1-yl-acetic Acid
CAS:Controlled Product<p>Applications An impurity arising in the synthesis of zoledronic acid (Z623500).<br></p>Formula:C5H6N2O2Color and Shape:BeigeMolecular weight:126.115-Decyano 5-Carboxymilrinone
CAS:Controlled Product<p>Impurity Milrinone Impurity 12<br>Applications 5-Decyano 5-Carboxymilrinone (Milrinone Impurity 12) is an impurity of Milrinone (M344680), a selective phosphodiesterase inhibitor with vasodilating and positive inotropic activity.<br>References Alousi, A.A., et al.: J. Cardiovasc Pharmacol., 5, 792 (1983); Maskin, C.S., et al.: Circulation, 67, 1065 (1983); Sinoway, L.S., et al.: J. Am. Coll. Cardiol., 2, 327 (1983); Baim, D.S., et al.: N. Engl. J. Med., 309, 748 (1983)<br></p>Formula:C12H10N2O3Color and Shape:Off-WhiteMolecular weight:230.22Deferasirox Methyl Ester
CAS:Controlled Product<p>Applications Deferasirox Methyl Ester is a derivative of Deferasirox (D228650); an orally active tridentate iron chelator.<br>References Hershko, C., et al.: Blood, 97, 1115 (2001); Galanello, R., et al.: J. Clin. Pharmacol., 43, 565 (2003); Nick, H., et al.: Curr. Med. Chem., 10, 1065 (2003)<br></p>Formula:C22H17N3O4Color and Shape:White To BeigeMolecular weight:387.39Parathion
CAS:Controlled Product<p>Stability Hygroscopic, Moisture Sensitive<br>Applications Parathion is an organophosphate insecticide used on cotton, rice and fruit trees.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Seifert, J., et al.: Environ. Toxicol. Pharmacol., 35, 200 (2013); Ciffroy, P., et al.: Environ. Toxicol. Chem., 32, 602 (2013);<br></p>Formula:C10H14NO5PSColor and Shape:YellowMolecular weight:291.26N-Dechloroethyl Cyclophosphamide
CAS:<p>Stability Reacts with DMSO<br>Applications A metabolite of Cyclophosphamide (C988580).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bohnenstengel, F., et al.: Eur. J. Clin. Pharmacol., 51, 297 (1996), Busse, D., et al.: J. Clin. Oncol., 15, 188 (1997), Roy, P., et al.: Drug Metab. Dispos., 27, 655 (1999),<br></p>Formula:C5H12ClN2O2PColor and Shape:NeatMolecular weight:198.59(R,S)-4-Hydroxy Cyclophosphamide-d4 Preparation Kit
CAS:Controlled ProductFormula:C7H11D4Cl2N2O3PColor and Shape:White To Off-WhiteMolecular weight:281.11(S)-(-)-3-Acetylthio-2-methylpropionic Acid
CAS:Controlled Product<p>Applications S-Acetylthio-2-methylpropionic Acid (S-AMPA) is a key chiral intermediate for Captopril (C175750) and other hypertension drugs.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Cushman, D., et al.: Biochem., 16, 5484 (1977), Ondetti, M., et al.: J. Med. Chem., 24, 355 (1981), Tseng, T., et al.: Cancer Lett., 62, 233 (1992),<br></p>Formula:C6H10O3SColor and Shape:ColourlessMolecular weight:162.214-Ethoxy-2-isopropyl-6-methylpyrimidine
CAS:Controlled Product<p>Applications 4-Ethoxy-2-isopropyl-6-methylpyrimidine, is the product of Diazinon (D416880) decomposition, an organophosphorus pesticide.<br>References Mekhakyan, L. A., et al.: Nov. Khim. Sredstva Zashch. , 62 (1979); Sovocool, G. W., et al.: J. Anal. Toxic., 5, 73 (1981);<br></p>Formula:C10H16N2OColor and Shape:NeatMolecular weight:180.25Bis(2-chloroethyl)-1,1,2,2-d4-amine Hydrochloride
CAS:Controlled Product<p>Applications Isotope labelled Bis(2-chloroethyl)amine is a cytotoxic metabolite of Cyclophosphamide; a deuterated analog of Nor-nitrogen mustard.<br>References Colvin, M., et al.: Cancer Res., 36, 1121 (1976), Ludeman, S., et al.: Drug Metab Dispos., 20, 337 (1992), Ludeman, S.M., et al.: J. Pharmaceut. Sci., 84, 393 (1995), Yu, L., et al.: Drug Metab. Dispos., 24, 1254 (1996),<br></p>Formula:C42H4H5Cl2N·ClHColor and Shape:NeatMolecular weight:182.51Epicaptopril
CAS:<p>Stability Air Sensitive<br>Applications Epicaptopril is an impurity of Captopril (C175750) which is an orally active angiotensin-converting enzyme (ACE) inhibitor used in the treatment of hypertension and congestive heart failure.<br>References Rubin, B., et al.: Eur. J Pharmacol., 51, 377 (1978);<br></p>Formula:C9H15NO3SColor and Shape:White To Off-WhiteMolecular weight:217.28Glufosinate-d3 Hydrochloride
CAS:Controlled Product<p>Stability Very Hygroscopic<br>Applications Labelled Glufosinate (G596952). Used as a herbicide.<br>References Abbas, H., et al.: J. Agric. Food Chem., 50, 5246<br></p>Formula:C52H3H9NO4P·ClHColor and Shape:White To Light BeigeMolecular weight:220.61Captopril
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Orally active angiotensin-converting enzyme (ACE) inhibitor. Neuroprotective & Neuroresearch Product.<br>References Rubin, B., et al.: Eur. J Pharmacol., 51, 377 (1978),<br></p>Formula:C9H15NO3SColor and Shape:NeatMolecular weight:217.29Miltefosine
CAS:Controlled Product<p>Applications A phospholipid drug with antineoplastic and antiprotozoal/antifungal properties, also acts as an Akt inhibitor, and under investigation as a potential therapy against HIV infection.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chugh, P., et al al.: Retrovirology, 5, 11 (2008), Dorio, T., et al.: Antimicrob. Agents Chemother., 52, 2855 (2008),<br></p>Formula:C21H46NO4PColor and Shape:NeatMolecular weight:407.57Zoledronic Acid-15N2,13C2
CAS:Controlled ProductFormula:C313C2H1015N2O7P2Color and Shape:NeatMolecular weight:276.06Ethylenediamine-N,N,N’,N’-tetraacetic Acid-13C4
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Labelled Ethylenediaminetetraacetic Acid (E917745). EDTA is a powerful chelating agent; EDTA forms stable complexes with most metal ions. EDTA is used in treatment of lead and heavy metal poisoning of farm animals.<br>References Heindorff, K., et al.: Mutat. Res., 115, 149 (1983), Grier, M.T., et al.: Ann. Pharmacother., 27, 1504 (1993), Krokidis, A.A., et al.: Anal. Chim. Acta, 535, 57 (2005),<br></p>Formula:C4C6H16N2O8Color and Shape:NeatMolecular weight:296.21336-Epi pravastatin sodium
CAS:<p>6-Epi pravastatin sodium salt is a synthetic compound with the same molecular formula and chemical structure as the natural product. It has been used in pharmacological studies, drug development, and research. 6-Epi pravastatin sodium salt is a metabolite of pravastatin.</p>Formula:C23H36O7•NaPurity:Min. 92.0 Area-%Molecular weight:447.51 g/molPravastatin lactone
CAS:<p>Pravastatin lactone is a prodrug of pravastatin that is hydrolyzed in vivo to its active form. It is used for the treatment of bowel disease and has been shown to have concentration-time curves that are linear and dose-dependent. Pravastatin lactone has an acidic pH, which may be due to the presence of carboxyl groups on the molecule. This drug also inhibits the activity of 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, which is an enzyme that catalyzes the conversion of HMG CoA to mevalonate in order to produce cholesterol. Pravastatin lactone also suppresses the production of fatty acids by inhibiting their synthesis at the level of acetyl-coenzyme A (acetyl-CoA). The drug has not shown any evidence of toxicity when administered to rats at doses up to 10 mg/kg body weight per day</p>Formula:C23H34O6Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:406.51 g/molNitrilotris(methylenephosphonic acid) (ca. 50% in water, ca. 2.2mol/L)
CAS:Formula:C3H12NO9P3Purity:95.0%Color and Shape:Liquid, Clear colourless to slightly pale yellow liquidMolecular weight:299.048Sodium (2R,3S,4S)-5-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)-2,3,4-trihydroxypentyl hydrogenphosphate dihydrate
CAS:Purity:97%Molecular weight:514.3599854Octadecylphosphonic acid
CAS:Formula:C18H39O3PPurity:98%Color and Shape:SolidMolecular weight:334.481Adenosine-5′-monophosphate monohydrate
CAS:Formula:C10H16N5O8PPurity:98%Color and Shape:SolidMolecular weight:365.239Phosphoenolpyruvate, monopotassium salt
CAS:<p>M02738 - Phosphoenolpyruvate, monopotassium salt</p>Formula:C3H4KO6PPurity:96%Color and Shape:Solid, PowderMolecular weight:206.131Adenosine 5′-monophosphate
CAS:Formula:C10H14N5O7PPurity:97%Color and Shape:Solid, Crystalline PowderMolecular weight:347.224(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(difluoro(phosphono)methyl)phenyl)propanoic acid
CAS:Purity:98%Molecular weight:517.42199714-Nitrophenyl phosphate disodium salt hexahydrate
CAS:Formula:C6H16NNa2O12PPurity:97%Color and Shape:Solid, Off-white to yellow crystalline powderMolecular weight:371.1423-Aminopropylphosphonic acid
CAS:Formula:C3H10NO3PPurity:95%Color and Shape:Solid, White to light yellow solidMolecular weight:139.091N-(CARBOXYMETHYL)-N-(PHOSPHONOMETHYL)-GLYCINE
CAS:Purity:97%Color and Shape:SolidMolecular weight:227.1089935((2-(6-Amino-9H-purin-9-yl)ethoxy)methyl)phosphonic acid
CAS:Formula:C8H12N5O4PPurity:95%Color and Shape:SolidMolecular weight:273.189
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