Nitrosamines and Derivatives
Nitrosamines are chemical compounds that contain a nitroso group (-NO) attached to a nitrogen atom, usually within a heterocyclic structure. These substances commonly form as by-products of chemical reactions, such as the nitrosation of amines in the presence of nitrites. Nitrosamines are known for their high toxicity and carcinogenic properties, especially in living organisms. Due to these effects, their presence in food products, cosmetics, and tobacco is strictly regulated. Nitrosamine derivatives, such as nitrosamides, also exhibit carcinogenic properties and may form in industrial processes, although some derivatives are being investigated for pharmaceutical applications due to their potential in certain biological reactions.
At CymitQuimica, we offer nitrosamines and their derivatives for research in toxicology, analytical chemistry, and pharmacology.
Found 55 products of "Nitrosamines and Derivatives"
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Molsidomine Impurity C ((2E)-(Morpholin-4-ylimino)-Acetonitrile)
CAS:Formula:C6H9N3OMolecular weight:139.16Morpholine
CAS:Controlled Product<p>Applications Morpholine, is used as selective inhibitors of cytochrome p450 2a13 in treatment of cancer. Morpholine is a building block in the preparation of the antibiotic Linezolid (L466500), the anticancer agent Gefitinib (G304000) and the analgetic Dextromoramide (M630190).<br> E0<br>References Hall, H. K., et al.: J. Am. Chem. Soc., 79 (20), 5441 (1957); Paladini, D., et al.: Biochem., 48, 5760 (2009); Bard, B., et al.: J. Med. Chem., 52, 3416 (2009);<br></p>Formula:C4H9NOColor and Shape:NeatMolecular weight:87.12Ethyl 2-diazoacetate (contains 4-13% Dichloromethane)
CAS:Purity:95.0%Color and Shape:LiquidMolecular weight:114.10399627685547Molsidomine
CAS:Controlled Product<p>Applications Molsidomine is an antianginal agent. Molsidomine is an effective therapeutic agents in the treatment of angina pectoris. Molsidomine is a sydnonimine derivative that acts as a heterocyclic direct nitric oxide donor.<br>References Tanayama, S. et al.: Xenobiotica, 4, 175 (1974); Yamada, M. et al.: Chem. Pharmac. Bull., 35, 3390 (1987); Messin, R. et al.: Adv. Ther., 23, 107 (2006);<br></p>Formula:C9H14N4O4Color and Shape:White To Off-WhiteMolecular weight:242.234-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (1.0 mg/mL in Acetonitrile)
CAS:Formula:C10H13N3O2Color and Shape:ColourlessMolecular weight:207.234-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone
CAS:Controlled ProductFormula:C10H13N3O2Color and Shape:Off-WhiteMolecular weight:207.234-(Methyl-d3-nitrosamino)-1-(3-pyridyl)-1-butanol
CAS:Controlled Product<p>Applications A deuterated metabolite of NNK (Cat. #M325750), a tobacco-specific nitrosamine.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hecht, S.S., et al.: Cancer Res., 40, 4144 (1980); Kutzer, C., et al.: J. Chromatog. Sci., 35, 1 (1997)<br></p>Formula:C102H3H12N3O2Color and Shape:NeatMolecular weight:212.26
