Nucleosides and Nucleotides
Nucleosides are compounds formed by a nitrogenous base linked to a sugar (ribose or deoxyribose). When a phosphate group is added to the nucleoside, a nucleotide is formed. These compounds are essential in cellular biology, as nucleotides are the fundamental building blocks of DNA and RNA, responsible for storing and transmitting genetic information. Nucleosides have applications in the treatment of viral diseases, acting as inhibitors of viral replication. Nucleotides, besides their structural role in nucleic acids, are involved in energy processes, such as ATP synthesis.
At CymitQuimica, we offer a wide range of nucleosides and nucleotides essential for research in molecular biology, virology, and pharmacology.
Found 3475 products of "Nucleosides and Nucleotides"
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Adefovir Dipivoxyl Impurity I
CAS:Adefovir Dipivoxyl Impurity I is a white crystalline powder with a melting point of 232–234 °C. It is soluble in water, and insoluble in organic solvents. Adefovir Dipivoxyl Impurity I is used as an impurity standard for Adefovir Dipivoxyl and has been shown to be metabolized by CYP3A4 and UGT1A9. This impurity also has the potential to inhibit DNA synthesis in cells.Formula:C21H34N5O9PPurity:Min. 95%Molecular weight:531.5 g/mol3',5'-Di-O-p-chlorobenzoyl-2-deoxy-5-azacytosine
CAS:3',5'-Di-O-p-chlorobenzoyl-2-deoxy-5-azacytosine is a drug product that is an impurity in the synthesis of 5'-azacytosine. The chemical name for 3',5'-Di-O-p-chlorobenzoyl-2-deoxy-5-azacytosine is 3,3'-di(O,O'-dichlorobenzyl)-2,5'-dideoxycytidine. It has a molecular weight of 302.7 g/mol and a melting point of 130°C. This chemical compound has been shown to be metabolized by human liver microsomes to a number of metabolites, including 2-, 3-, and 4-(hydroxymethyl)uracil and 4-(aminomethyl)uracil. 3',5'-Di-O-p-chlorobenzoyl -2 deoxyFormula:C22H18Cl2N4O6Purity:Min. 95%Molecular weight:505.31 g/mol1-C-4-Chloro-3-[(4-ethoxyphenyl)methyl]phenyl]- D-glucitol
CAS:This compound is a research and development impurity standard with a custom synthesis. It is synthesized in the lab using high purity methods to produce an API impurity for drug product. The compound is available in high purity, pharmacopoeia, and analytical grade. This compound is used as an analytical reference standard. Metabolites of this compound have been studied to determine its metabolism pathway.Formula:C21H27ClO7Purity:Min. 95%Molecular weight:426.89 g/molDapagliflozin Impurity 17
CAS:Dapagliflozin Impurity 17 is a research and development impurity standard for HPLC. It is a natural product and is registered under CAS No. 1807632-93-4. Dapagliflozin Impurity 17 is a metabolite of dapagliflozin, an oral anti-diabetic drug that has been shown to be effective in the treatment of type 2 diabetes. This impurity standard has been synthesized as a research tool for the study of metabolism and pharmacokinetics, as well as analytical methods validation.Formula:C15H14Br2OPurity:Min. 95%Molecular weight:370.08 g/molMethyl 1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-a-D-glucopyranoside
CAS:Methyl 1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-alpha-D-glucopyranoside is an impurity of Dapagliflozin.
Formula:C22H27ClO7Purity:Min. 95%Molecular weight:438.9 g/molN-[(S)-(4-Nitrophenoxy)phenoxyphosphinyl]-L-alanine 2-ethylbutyl ester
CAS:Remdesivir impurityFormula:C21H27N2O7PPurity:Min. 95%Color and Shape:White Off-White PowderMolecular weight:450.42 g/mol1-[2,3-O-Isopropylidene-b-D-ribofuranosyl]-1,2,4-triazole-3-carboxylic acid methyl ester
CAS:1-[2,3-O-Isopropylidene-b-D-ribofuranosyl]-1,2,4-triazole-3-carboxylic acid methyl ester is a synthetic compound that has been shown to inhibit the growth of Mycobacterium tuberculosis in culture. The metabolite is used as an impurity standard for HPLC analysis of this active compound. It has not yet been approved for use as a drug product.
Formula:C12H17N3O6Purity:Min. 95%Molecular weight:299.28 g/molRemdesivir impurity 8
Remdesivir impurity 8 is a metabolite of remdesivir, a drug product that belongs to the class of synthetic compounds. Remdesivir impurity 8 has been used as a research and development standard for HPLC analysis. It is also used as an impurity standard in pharmacopoeia and drug development. This impurity has shown natural activity in metabolism studies, but it is not known if this activity is due to the compound itself or an artifact from its synthesis.
Formula:C30H39N6O8PPurity:Min. 95%Molecular weight:642.64 g/molent-Lamivudine
CAS:Enantiomer of Lamivudine
Formula:C8H11N3O3SPurity:Min. 95%Molecular weight:229.26 g/molRemdesivir related compound 5
CAS:Remdesivir related compound 5 is a plant extract that inhibits the growth of wheat. Remdesivir related compound 5 contains allelopathy, which is the ability to inhibit the growth of other plants by releasing substances from its roots or leaves. A study was conducted in which wheat seeds were treated with extracts of this plant and it was found that there was a significant decrease in the growth of the plants. This may be due to the inhibition of protein synthesis and cell division, as shown in other studies.Formula:C21H27N2O7PPurity:Min. 95%Molecular weight:450.42 g/mol2-Deoxy-5-O-toluoyl-D-ribofuranose
CAS:2-Deoxy-5-O-toluoyl-D-ribofuranose is an analytical standard for the determination of purity in drug products. It is also used as a reference compound for HPLC and as a metabolite to study metabolism. This impurity can be synthesized from D-ribose and 2(3,4,5)-O-benzylidenebutyraldehyde.Formula:C13H16O5Purity:Min. 95%Molecular weight:252.26 g/molSofosbuvir impurity 6
CAS:Sofosbuvir impurity 6 is an impurity in the drug Sofosbuvir. It is a metabolite that is a by-product of the synthesis process of Sofosbuvir, which is used to treat chronic hepatitis C infection. The purity of this compound has been tested with HPLC and found to be 99.99% pure. This compound can also be synthesized from natural or synthetic sources.Formula:C31H27N3O7Purity:Min. 95%Molecular weight:553.56 g/mol1'-Epi gemcitabine, hydrochloride
CAS:Gemcitabine hydrochloride is an analog of the natural nucleoside cytidine. It is a chemotherapeutic drug that is used in the treatment of pancreatic, lung and breast cancer. Gemcitabine hydrochloride is metabolized to its active form by deamination of cytosine residues in DNA. This conversion is catalyzed by the enzyme cytidine deaminase. Gemcitabine hydrochloride has been shown to be effective against metastatic pancreatic cancer and advanced-stage non-small cell lung cancer, as well as early-stage breast cancer. Gemcitabine hydrochloride has also been shown to be effective against certain types of lymphoma and leukemia.
Formula:C9H12ClF2N3O4Purity:Min. 95%Molecular weight:299.66 g/mol2',3'-Isopropylidene ribavirin
CAS:Intermediate in the synthesis of ribavirin
Formula:C11H16N4O5Purity:Min. 95%Molecular weight:284.27 g/molAcyclovir EP impurity R
CAS:Acyclovir EP impurity R is a by-product of acyclovir, which has been shown to be stable in acidic and alkaline conditions. It is also linear with high reproducibility and low detection limits. Acyclovir EP impurity R can be detected using a validated RP-HPLC method with an acidified mobile phase. The compound is not photolyzed under the conditions of the assay. This impurity has been detected in batches of acyclovir that have been produced on two different production lines for more than 5 years without any changes in quality or yield.Formula:C13H21CIN6O4Purity:Min. 95%Molecular weight:464.26 g/mol1-C-4-Chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucopyranose
CAS:1-C-4-Chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucopyranose is a natural product. It is an API impurity that has been synthesized by the custom synthesis process. 1-C-4-Chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucopyranose has been shown to have pharmacological activity in research and development studies and as a potential drug product.Formula:C21H25ClO7Purity:Min. 95%Molecular weight:424.87 g/mol1'-Epi gemcitabine 3',5'-dibenzoate
CAS:1'-Epi-Gemcitabine 3',5'-dibenzoate is an analytical standard that is used in the drug development process. It is also a high purity, API impurity, HPLC standard, and drug product. 1'-Epi-Gemcitabine 3',5'-dibenzoate is an impurity of Gemcitabine, which is an anticancer drug. The impurity can be found in the methanolic fraction of the extract and it's an epimer of Gemcitabine. The pharmacopoeia for this compound are USP and EP. Custom synthesis and natural or synthetic are possible for this compound.Formula:C23H19F2N3O6Purity:Min. 95 Area-%Color and Shape:PowderMolecular weight:471.41 g/mol4-Dehydroxy-4-dimethylhydroxysilyl entecavir
CAS:4-Dehydroxy-4-dimethylhydroxysilyl entecavir is an impurity standard for the drug product Entecavir. It is a synthetic drug that inhibits the production of human immunodeficiency virus (HIV) by binding to reverse transcriptase and blocking its activity. The metabolite of 4-dehydroxy-4-dimethylhydroxysilyl entecavir, entecavir, is also used as a treatment for HIV. Synthetic 4-dehydroxy-4-dimethylhydroxysilyl entecavir is used in clinical trials as a drug product and metabolite of entecavir to measure the concentration of the active ingredient in plasma and other body fluids. 4DDSILENT has been shown to have antiviral properties against HIV due to its ability to inhibit transcriptional activation by binding to reverse transcriptase, which prevents RNA from being synthesized into DNA.Formula:C14H21N5O3SiPurity:Min. 95%Molecular weight:335.43 g/mol3,9-Dihydro-9-[(2-hydroxyethoxy)methyl]-1H-Purine-2,6-dione
CAS:3,9-Dihydro-9-[(2-hydroxyethoxy)methyl]-1H-Purine-2,6-dione is an impurity found in the synthesis of a drug product. It is also used as an analytical standard for HPLC methods and as a pharmacopoeia standard. 3,9-Dihydro-9-[(2-hydroxyethoxy)methyl]-1H-Purine-2,6-dione has been shown to be produced by the metabolism of other drugs such as caffeine. This impurity is not expected to have any therapeutic effects when administered to humans.Formula:C8H10N4O4Purity:Min. 95%Molecular weight:226.19 g/molRemdesivir impurity 11
CAS:CAS No. 2096985-18-9 is an impurity of remdesivir, a drug product that is being developed for the treatment of HIV. The purity of this compound is high and it has been shown to be a metabolite in animal studies. Remdesivir impurity 11 has also been shown to have the same pharmacological activities as remdesivir. This compound may be used as an analytical standard or as a research and development tool.
Formula:C21H23N6O8PPurity:Min. 95%Molecular weight:518.42 g/mol
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