Nucleosides and Nucleotides
Nucleosides are compounds formed by a nitrogenous base linked to a sugar (ribose or deoxyribose). When a phosphate group is added to the nucleoside, a nucleotide is formed. These compounds are essential in cellular biology, as nucleotides are the fundamental building blocks of DNA and RNA, responsible for storing and transmitting genetic information. Nucleosides have applications in the treatment of viral diseases, acting as inhibitors of viral replication. Nucleotides, besides their structural role in nucleic acids, are involved in energy processes, such as ATP synthesis.
At CymitQuimica, we offer a wide range of nucleosides and nucleotides essential for research in molecular biology, virology, and pharmacology.
Found 3470 products of "Nucleosides and Nucleotides"
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Acyclovir EP impurity R
CAS:Acyclovir EP impurity R is a by-product of acyclovir, which has been shown to be stable in acidic and alkaline conditions. It is also linear with high reproducibility and low detection limits. Acyclovir EP impurity R can be detected using a validated RP-HPLC method with an acidified mobile phase. The compound is not photolyzed under the conditions of the assay. This impurity has been detected in batches of acyclovir that have been produced on two different production lines for more than 5 years without any changes in quality or yield.Formula:C13H21CIN6O4Purity:Min. 95%Molecular weight:464.26 g/molRemsesivir related compound 11
CAS:Remsesivir related compound 11 is a research and development chemical that is used as an analytical, drug development, or impurity standard. It is a high purity, pure substance that can be custom synthesized or natural. Remsesivir related compound 11 has been shown to be metabolized by cytochrome p450 enzymes and glutathione reductase and has shown pharmacopoeia activities. Remsesivir related compound 11 can also be used as a HPLC standard for the detection of metabolites in pharmaceutical products.Formula:C15H23Cln04pPurity:Min. 95%Molecular weight:347.78 g/molRemdesivir impurity 4
CAS:Remdesivir is an antiviral drug that inhibits the viral enzyme, RNA-dependent RNA polymerase. Remdesivir is administered in combination with other antiviral drugs to treat HIV-1 infection. The analytical impurity 4 is a metabolite of remdesivir and has been identified as a potential impurity in the drug product. CAS No. 2096985-18-9 is the molecular weight of this impurity. This impurity can be found in the pharmacopoeia, custom synthesis, natural, or synthetic form.Formula:C21H27N2O7PPurity:Min. 95%Molecular weight:450.42 g/mol1-(2-Deoxy-beta-D-xylofuranosyl)-5-methyluracil
CAS:1-(2-Deoxy-beta-D-xylofuranosyl)-5-methyluracil (1DXP) is a nucleoside that inhibits the enzyme UDP glucose pyrophosphorylase. This enzyme is involved in the synthesis of uridine nucleotides, which are required for RNA and DNA synthesis. 1DXP has been shown to be effective against hepatitis B virus and lymphocytic leukemia cells in vitro. The mechanism of action of 1DXP is not well understood, but it may be related to the inhibition of protein synthesis or cellular metabolism. It may also inhibit the enzyme amino transferase, which is important for the synthesis of aromatic amino acids such as phenylalanine and tyrosine.Formula:C10H14N2O5Purity:Min. 95%Molecular weight:242.23 g/mola-Ribavirin (impurity B)
CAS:Controlled ProductRibavirin is an antiviral drug that inhibits the synthesis of RNA and DNA. It is used to treat human immunodeficiency virus (HIV) infection, hepatitis B, and influenza A. Ribavirin is a nucleoside analog that acts as an antimetabolite by inhibiting acid synthesis in the host cell and therefore blocking viral replication. Ribavirin has been shown to inhibit dna viruses like herpes simplex virus type 1 and 2, as well as RNA viruses like influenza A and respiratory syncytial virus. Ribavirin also binds to the ribonucleotide reductase enzyme, which is necessary for the production of deoxyribonucleotides from ribonucleotides during DNA synthesis, thereby interfering with DNA replication.Formula:C8H12N4O5Purity:Min. 95%Molecular weight:244.2 g/mol4-Amino-1-[3,5-di-O-(4-chlorobenzoyl)-2-deoxy-α-D-ribofuranosyl]-1,3,5-triazin-2(1H)-one
CAS:4-Amino-1-[3,5-di-O-(4-chlorobenzoyl)-2-deoxy-α-D-ribofuranosyl]-1,3,5-triazin-2(1H)-one (4AAT) is an analytical chemical that is used for research and development purposes. 4AAT is a metabolite of the antibiotic ampicillin and has been identified as an impurity in the drug product. It can be synthesized from 2-(4'-chlorophenyl)benzaldehyde, 3,5'-di-O-(4'-chlorobenzoyl)-2',3'-dideoxyribose and sodium azide in a two step process with 98% purity. 4AATs are also found to be present in natural products such as honey or sugar cane juice.
Formula:C22H18Cl2N4O6Purity:Min. 95%Color and Shape:White Off-White PowderMolecular weight:505.31 g/molRemdesivir related compound 5
CAS:Remdesivir related compound 5 is a plant extract that inhibits the growth of wheat. Remdesivir related compound 5 contains allelopathy, which is the ability to inhibit the growth of other plants by releasing substances from its roots or leaves. A study was conducted in which wheat seeds were treated with extracts of this plant and it was found that there was a significant decrease in the growth of the plants. This may be due to the inhibition of protein synthesis and cell division, as shown in other studies.Formula:C21H27N2O7PPurity:Min. 95%Molecular weight:450.42 g/mol2-Deoxy-5-O-toluoyl-D-ribofuranose
CAS:2-Deoxy-5-O-toluoyl-D-ribofuranose is an analytical standard for the determination of purity in drug products. It is also used as a reference compound for HPLC and as a metabolite to study metabolism. This impurity can be synthesized from D-ribose and 2(3,4,5)-O-benzylidenebutyraldehyde.Formula:C13H16O5Purity:Min. 95%Molecular weight:252.26 g/molRemdesivir impurity 8
Remdesivir impurity 8 is a metabolite of remdesivir, a drug product that belongs to the class of synthetic compounds. Remdesivir impurity 8 has been used as a research and development standard for HPLC analysis. It is also used as an impurity standard in pharmacopoeia and drug development. This impurity has shown natural activity in metabolism studies, but it is not known if this activity is due to the compound itself or an artifact from its synthesis.
Formula:C30H39N6O8PPurity:Min. 95%Molecular weight:642.64 g/molMethyl 1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-a-D-glucopyranoside
CAS:Methyl 1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-alpha-D-glucopyranoside is an impurity of Dapagliflozin.
Formula:C22H27ClO7Purity:Min. 95%Molecular weight:438.9 g/mol1-[2,3-O-Isopropylidene-b-D-ribofuranosyl]-1,2,4-triazole-3-carboxylic acid methyl ester
CAS:1-[2,3-O-Isopropylidene-b-D-ribofuranosyl]-1,2,4-triazole-3-carboxylic acid methyl ester is a synthetic compound that has been shown to inhibit the growth of Mycobacterium tuberculosis in culture. The metabolite is used as an impurity standard for HPLC analysis of this active compound. It has not yet been approved for use as a drug product.
Formula:C12H17N3O6Purity:Min. 95%Molecular weight:299.28 g/molAciclovir EP impurity J
CAS:Aciclovir EP impurity J is a drug product that is used as an analytical standard in HPLC. Aciclovir EP impurity J is the natural metabolite of aciclovir, which is an antiviral drug. It is not active against herpesviruses but has been shown to inhibit the growth of human cells infected with cytomegalovirus. Aciclovir EP impurity J has been studied for its effects on drug metabolism and pharmacokinetics. Aciclovir EP impurity J has been shown to be excreted primarily in urine, with some excretion in the feces.Formula:C14H16N10O4Purity:Min. 95%Molecular weight:388.34 g/molSofosbuvir impurity 3
CAS:Sofosbuvir impurity 3 is a research and development, impurity standard, custom synthesis, drug product, synthetic, high purity, pharmacopoeia, drug development and analytical. Sofosbuvir impurity 3 is a metabolite of sofosbuvir which has been studied in metabolism studies using HPLC. This compound has also been shown to inhibit the growth of some bacteria.Formula:C22H29FN3O9PPurity:Min. 95%Molecular weight:529.45 g/mol1'-Epi gemcitabine 3',5'-dibenzoate
CAS:1'-Epi-Gemcitabine 3',5'-dibenzoate is an analytical standard that is used in the drug development process. It is also a high purity, API impurity, HPLC standard, and drug product. 1'-Epi-Gemcitabine 3',5'-dibenzoate is an impurity of Gemcitabine, which is an anticancer drug. The impurity can be found in the methanolic fraction of the extract and it's an epimer of Gemcitabine. The pharmacopoeia for this compound are USP and EP. Custom synthesis and natural or synthetic are possible for this compound.Formula:C23H19F2N3O6Purity:Min. 95 Area-%Color and Shape:PowderMolecular weight:471.41 g/molAcyclovir EP Impurity Q
Acyclovir EP Impurity Q is a drug product that is used as the impurity standard for Acyclovir EP. It is a natural metabolite of acyclovir and may be found in the urine of patients taking this drug. Acyclovir EP Impurity Q has shown to have antiviral activity against herpes simplex virus type 1 and type 2. The structure of this compound has been determined by nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry.Purity:Min. 95%Valaciclovir Related Compound E
CAS:Valaciclovir Related Compound E is a white crystalline powder that has an appearance similar to acyclovir, with a melting point of 164-167°C. It is soluble in water and methanol. The compound is used as a medicament and also acts as an intermediate for the synthesis of other pharmaceutical products. Valaciclovir Related Compound E can be synthesized from valaciclovir by reacting it with ethyl chloroformate, followed by recrystallization from pyridine and chloroform. This process produces the desired product in high purity under good yield. Valaciclovir Related Compound E is a white crystalline powder that has an appearance similar to acyclovir, with a melting point of 164-167°C. It is soluble in water and methanol. The compound is used as a medicament and also acts as an intermediate for the synthesis of other pharmaceutical products. ValacFormula:C21H26N6O6Purity:Min. 95%Molecular weight:458.47 g/molAdefovir Dipivoxyl Impurity I
CAS:Adefovir Dipivoxyl Impurity I is a white crystalline powder with a melting point of 232–234 °C. It is soluble in water, and insoluble in organic solvents. Adefovir Dipivoxyl Impurity I is used as an impurity standard for Adefovir Dipivoxyl and has been shown to be metabolized by CYP3A4 and UGT1A9. This impurity also has the potential to inhibit DNA synthesis in cells.Formula:C21H34N5O9PPurity:Min. 95%Molecular weight:531.5 g/molEmpagliflozin tetraacetate
CAS:Empagliflozin tetraacetate is a drug product that has been manufactured by chemical synthesis. It is a white to off-white crystalline powder with a molecular weight of 597.7 and a purity of 98.2%. Empagliflozin tetraacetate has been formulated as the hydrochloride salt, which is soluble in water and alcohols. The USP/BP/EP specifications for this drug are 5% impurity standard, analytical, API impurity, Synthetic, Metabolism studies, niche, High purity>. This drug product can be used in research and development as well as for manufacturing pharmaceutical products. It is not intended for use in humans or animals.Formula:C27H29ClO10Purity:Min. 95%Molecular weight:548.97 g/molCreatine monohydrate
CAS:Creatine monohydrate powers ATP for short, high-intensity activities in muscles and brain.Formula:C4H11N3O3Purity:99.87%Color and Shape:White SolidMolecular weight:149.15LY450108
CAS:LY450108 is a potentiator of the AMPA receptor that can be used in Parkinson's disease studies.Formula:C19H22F2N2O3SPurity:98.87% - 99.91%Color and Shape:SolidMolecular weight:396.45(S)-AMPA
CAS:(S)-AMPA is an active isomer of AMPA and a selective agonist of AMPA.Formula:C7H10N2O4Color and Shape:SolidMolecular weight:186.17Diapocynin
CAS:Diapocynin (Dehydrodiacetovanillone), a dimer of Apocynin, acts as an orally administered inhibitor of NADPH oxidase.Formula:C18H18O6Color and Shape:SolidMolecular weight:330.33(R)-Oxiracetam
CAS:(R)-Oxiracetam is the (R)-enantiomer of the nootropic drug oxiracetam. Oxiracetam is a nootropic drug of the racetam family and stimulant.Formula:C6H10N2O3Color and Shape:SolidMolecular weight:158.16Gemcitabine monophosphate
CAS:R306465, a potent HDAC1/8 inhibitor, has broad antitumor effects (IC50: 30-300 nM) on solid and blood cancers.Formula:C9H12F2N3O7PColor and Shape:SolidMolecular weight:343.18Sarcolysine hydrochloride
CAS:Sarcolysine hydrochloride, also known as Melphalan HCl, is a nitrogen mustard and alkylating agent that has been studied for use in multiple myeloma therapy.Formula:C13H19Cl3N2O2Color and Shape:SolidMolecular weight:341.66S07-2010
CAS:S07-2010 is a pan-Aldo-Keto Reductase 1C3 (AKR1C3) inhibitor with potential anti-cancer activity, inducing apoptosis in A549/DDP cells.Formula:C19H21N3O3SPurity:98.13%Color and Shape:SolidMolecular weight:371.45CNV-2197944
CAS:CNV-2197944 is a novel, small molecule, state-dependent calcium channel blocker, designed to selectively inhibit highly active Cav2.2 channels.Formula:C19H20F3N3O3SColor and Shape:SolidMolecular weight:427.44Galidesivir triphosphate
CAS:Galidesivir triphosphate halts viral RNA replication by inhibiting RDRP and NS5B, and combats Ebola in mice; derived from prodrug Galidesivir.Formula:C11H18N5O12P3Purity:98%Color and Shape:SolidMolecular weight:505.21Apadenoson
CAS:Apadenoson: potent A2 agonist, A3 inhibitor (IC 45 nM), anti-inflammatory, for neurological research.Formula:C23H30N6O6Purity:98%Color and Shape:SolidMolecular weight:486.521-Oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium
CAS:Oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium (18:1 Lyso-PS) modulates macrophage G2A for neutrophil inflammation resolution.Formula:C24H45NNaO9PColor and Shape:SolidMolecular weight:545.586Adefovir diphosphate
CAS:Adefovir monophosphate: antiviral ANP active against HBV, herpes; ntRTI for hepatitis B, not HIV-1 effective.Formula:C8H13N5O7P2Color and Shape:SolidMolecular weight:353.172'-Deoxy-2',2'-difluorouridine
CAS:Gemcitabine metaboliteFormula:C9H10F2N2O5Purity:Min. 95%Color and Shape:White PowderMolecular weight:264.19 g/molEmtricitabine impurity 17
CAS:Please enquire for more information about Emtricitabine impurity 17 including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C8H10FN3O4SPurity:Min. 95%Molecular weight:263.24 g/molAPX-115
CAS:APX-115 (Ewha-18278) (Ewha-18278) is a potent, orally active pan NADPH oxidase (Nox) inhibitor (Kis: 1.08 μM, 0.57 μM, and 0.63 μM for Nox1, Nox2, and Nox4).Formula:C17H18ClN3OPurity:98.62%Color and Shape:SolidMolecular weight:315.8Ref: TM-T10354
1mg34.00€5mg75.00€10mg110.00€25mg222.00€50mg334.00€100mg475.00€500mg964.00€1mL*10mM (DMSO)92.00€Phox-I2
CAS:Phox-I2 is an NOX2-specific inhibitor. Phox-I2 reverts ROS-accumulation and leads to refusion of mitochondrial networks.
Formula:C18H15N3O4Purity:99.73%Color and Shape:SolidMolecular weight:337.33HTS07545
CAS:HTS07545, an SQOR inhibitor (IC50: 30nM), slows H2S breakdown, researched for heart failure.
Formula:C22H18N2O3Purity:99.71%Color and Shape:SolidMolecular weight:358.39S19-1035
S19-1035: potent AKR1C3 inhibitor with 3.04 nM IC50, useful for tumor research.
Formula:C19H17ClN2O3Purity:99.98%Color and Shape:SoildMolecular weight:356.80N6-(2-Phenylethyl)adenosine
CAS:N6-(2-Phenylethyl)adenosine (N6-Phenethyladenosine) is an adenosine derivative and an agonist of adenosine receptors with Ki values of 11.8 nM and 30.1 nM forFormula:C18H21N5O4Purity:99.83%Color and Shape:SolidMolecular weight:371.39Meropenem EP impurity A
CAS:Meropenem EP impurity A is a heterocyclic nitro compound that is used to treat various infectious diseases. Meropenem EP impurity A is an inhibitor of the toll-like receptor, which is a protein that recognizes and binds to bacterial lipopolysaccharide and mediates inflammation. This drug may be effective in treating colorectal carcinoma, autoimmune diseases, chronic bronchitis, cancer, and other inflammatory diseases. Meropenem EP impurity A also has anti-cancer properties due to its structural similarity with the chemotherapeutic agent 5-fluorouracil. Meropenem EP impurity A inhibits the synthesis of proteins by binding to the aminoacyl-tRNA synthetase enzyme and blocking the production of proteins vital for cell division.Formula:C17H27N3OS6Purity:95%NmrColor and Shape:PowderMolecular weight:401.5 g/molMolnupiravir
CAS:Molnupiravir (EIDD-2801) is an isopropyl ester prodrug of the ribonucleoside analog EIDD-1931 with oral bioavailability.Cost-effective and quality-assured.Formula:C13H19N3O7Purity:99.81% - 99.98%Color and Shape:SolidMolecular weight:329.31Ref: TM-T60951
1g973.00€5mg38.00€10mg57.00€25mg74.00€50mg113.00€100mg177.00€200mg334.00€500mg710.00€1mL*10mM (DMSO)63.00€Peldesine
CAS:Peldesine (BCX 34), an oral purine nucleoside phosphorylase blocker, halts T-cell growth; used in CTCL, psoriasis, HIV research. IC50: 800 nM.Formula:C12H11N5OPurity:99.27% - 99.9%Color and Shape:SolidMolecular weight:241.25Ref: TM-T12399
1mg108.00€5mg260.00€10mg416.00€25mg690.00€50mg964.00€100mg1,305.00€500mg2,592.00€1mL*10mM (DMSO)286.00€PSI 7976
CAS:PSI 7976 is an analog of the nucleophilic attack drug, ribavirin. PSI 7976 inhibits the hepatitis C virus (HCV) replicon by inhibiting the function of the NS5B polymerase. In clinical studies, PSI 7976 has been shown to be active against HCV genotype 1 and 3. It has also been shown to inhibit replication of HIV-1 in vitro and to act synergistically with lamivudine against HIV-1 in human cells. PSI 7976 may be useful as a potential antiviral agent for treatment of other viral infections such as hepatitis B virus (HBV), herpes simplex virus type 2 (HSV-2), or cytomegalovirus (CMV).Formula:C22H29FN3O9PPurity:Min. 95%Molecular weight:529.45 g/mol6-Pterinyl folic acid
CAS:6-Pterinyl folic acid is a chemical reagent that is used in the synthesis of pteridine derivatives. It is also used to prepare sulfates and esters of folic acid. 6-Pterinyl folic acid can be synthesized by reacting glutamic anhydride with trifluoroacetic acid and dimethylformamide. It reacts with sulfate ions to produce 6-pterinyl sulfate, which can then be hydrolyzed to release 6-pterinyl folic acid. The reagent can be used in the manufacture of fluoroquinolones, antibiotics that are used to treat a variety of bacterial infections including tuberculosis.Formula:C26H24N12O7Purity:Min. 95%Molecular weight:616.55 g/molDapagliflozin Impurity 26
CAS:Dapagliflozin Impurity 26 is an impurity that is found in the chemical analysis of Dapagliflozin. It is a metabolite, which is not present in the drug product and does not have any biological activity. Dapagliflozin Impurity 26 has been shown to be a high purity, analytical standard for HPLC and can be used as an API impurity for drug development. This compound can also be synthesized by natural or synthetic means.Purity:Min. 95%Methyl 2-deoxy-D-ribopyranoside
CAS:Methyl 2-deoxy-D-ribopyranoside (2DDR) is a natural compound that can be found as an impurity in some pharmaceuticals. The chemical structure of 2DDR is similar to 6-fluoro-3-indoxyl beta-D-galactopyranoside, which is used to treat tuberculosis. The metabolism of 2DDR has been studied, and it has been found that this metabolite is excreted in the urine unchanged or conjugated with glucuronic acid. This product can be used for drug development and research and development. It can also be used as an impurity standard for HPLC analysis or as a custom synthesis for niche applications.Formula:C6H12O4Purity:Min. 95%Color and Shape:PowderMolecular weight:148.16 g/molGalidesivir dihydrochloride
CAS:Galidesivir inhibits RdRP; has broad antiviral effects on various RNA viruses; effective against Ebola, Marburg in animals.Formula:C11H17Cl2N5O3Color and Shape:SolidMolecular weight:338.19Zidovudine diphosphate
CAS:Zidovudine diphosphate, an NRTI antiretroviral, treats HIV/AIDS by blocking reverse transcriptase, preventing viral DNA synthesis.Formula:C10H15N5O10P2Color and Shape:SolidMolecular weight:427.2Carbovir
CAS:Carbovir, an NRTI, induces mitochondrial toxicity in human liver cancer cells.Formula:C11H13N5O2Color and Shape:SolidMolecular weight:247.25NOX2-IN-1
CAS:NOX2-IN-1 (compound 10) serves as an inhibitor of the enzyme nicotinamide adenine dinucleotide phosphate oxidase isoform 2 (NOX2).Formula:C22H22N4O3Color and Shape:SolidMolecular weight:390.44NOX2-IN-2
CAS:NOX2-IN-2 (compound 33) is a potent inhibitor of NOX2, disrupting the p47phox-p22phox protein-protein interaction with a dissociation constant (K i) of 0.24 μM.Formula:C25H25N7O3Color and Shape:SolidMolecular weight:471.51
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