Nucleosides and Nucleotides
Nucleosides are compounds formed by a nitrogenous base linked to a sugar (ribose or deoxyribose). When a phosphate group is added to the nucleoside, a nucleotide is formed. These compounds are essential in cellular biology, as nucleotides are the fundamental building blocks of DNA and RNA, responsible for storing and transmitting genetic information. Nucleosides have applications in the treatment of viral diseases, acting as inhibitors of viral replication. Nucleotides, besides their structural role in nucleic acids, are involved in energy processes, such as ATP synthesis.
At CymitQuimica, we offer a wide range of nucleosides and nucleotides essential for research in molecular biology, virology, and pharmacology.
Found 3470 products of "Nucleosides and Nucleotides"
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Peldesine
CAS:Peldesine (BCX 34), an oral purine nucleoside phosphorylase blocker, halts T-cell growth; used in CTCL, psoriasis, HIV research. IC50: 800 nM.Formula:C12H11N5OPurity:99.27% - 99.9%Color and Shape:SolidMolecular weight:241.25Ref: TM-T12399
1mg108.00€5mg260.00€10mg416.00€25mg690.00€50mg964.00€100mg1,305.00€500mg2,592.00€1mL*10mM (DMSO)286.00€PSI 7976
CAS:PSI 7976 is an analog of the nucleophilic attack drug, ribavirin. PSI 7976 inhibits the hepatitis C virus (HCV) replicon by inhibiting the function of the NS5B polymerase. In clinical studies, PSI 7976 has been shown to be active against HCV genotype 1 and 3. It has also been shown to inhibit replication of HIV-1 in vitro and to act synergistically with lamivudine against HIV-1 in human cells. PSI 7976 may be useful as a potential antiviral agent for treatment of other viral infections such as hepatitis B virus (HBV), herpes simplex virus type 2 (HSV-2), or cytomegalovirus (CMV).Formula:C22H29FN3O9PPurity:Min. 95%Molecular weight:529.45 g/mol6-Pterinyl folic acid
CAS:6-Pterinyl folic acid is a chemical reagent that is used in the synthesis of pteridine derivatives. It is also used to prepare sulfates and esters of folic acid. 6-Pterinyl folic acid can be synthesized by reacting glutamic anhydride with trifluoroacetic acid and dimethylformamide. It reacts with sulfate ions to produce 6-pterinyl sulfate, which can then be hydrolyzed to release 6-pterinyl folic acid. The reagent can be used in the manufacture of fluoroquinolones, antibiotics that are used to treat a variety of bacterial infections including tuberculosis.Formula:C26H24N12O7Purity:Min. 95%Molecular weight:616.55 g/molDapagliflozin Impurity 26
CAS:Dapagliflozin Impurity 26 is an impurity that is found in the chemical analysis of Dapagliflozin. It is a metabolite, which is not present in the drug product and does not have any biological activity. Dapagliflozin Impurity 26 has been shown to be a high purity, analytical standard for HPLC and can be used as an API impurity for drug development. This compound can also be synthesized by natural or synthetic means.Purity:Min. 95%Methyl 2-deoxy-D-ribopyranoside
CAS:Methyl 2-deoxy-D-ribopyranoside (2DDR) is a natural compound that can be found as an impurity in some pharmaceuticals. The chemical structure of 2DDR is similar to 6-fluoro-3-indoxyl beta-D-galactopyranoside, which is used to treat tuberculosis. The metabolism of 2DDR has been studied, and it has been found that this metabolite is excreted in the urine unchanged or conjugated with glucuronic acid. This product can be used for drug development and research and development. It can also be used as an impurity standard for HPLC analysis or as a custom synthesis for niche applications.Formula:C6H12O4Purity:Min. 95%Color and Shape:PowderMolecular weight:148.16 g/molGalidesivir dihydrochloride
CAS:Galidesivir inhibits RdRP; has broad antiviral effects on various RNA viruses; effective against Ebola, Marburg in animals.Formula:C11H17Cl2N5O3Color and Shape:SolidMolecular weight:338.19Zidovudine diphosphate
CAS:Zidovudine diphosphate, an NRTI antiretroviral, treats HIV/AIDS by blocking reverse transcriptase, preventing viral DNA synthesis.Formula:C10H15N5O10P2Color and Shape:SolidMolecular weight:427.2Carbovir
CAS:Carbovir, an NRTI, induces mitochondrial toxicity in human liver cancer cells.Formula:C11H13N5O2Color and Shape:SolidMolecular weight:247.25NOX2-IN-1
CAS:NOX2-IN-1 (compound 10) serves as an inhibitor of the enzyme nicotinamide adenine dinucleotide phosphate oxidase isoform 2 (NOX2).Formula:C22H22N4O3Color and Shape:SolidMolecular weight:390.44NOX2-IN-2
CAS:NOX2-IN-2 (compound 33) is a potent inhibitor of NOX2, disrupting the p47phox-p22phox protein-protein interaction with a dissociation constant (K i) of 0.24 μM.Formula:C25H25N7O3Color and Shape:SolidMolecular weight:471.51Emtricitabine triphosphate tetrasodium salt
CAS:Emtricitabine triphosphate tetrasodium salt is the tetrasodium salt form of the phosphorylated anabolite (-)-Emtricitabine triphosphate, an active nucleosideFormula:C8H9FN3Na4O12P3SPurity:98%Color and Shape:SolidMolecular weight:575.11ES 936
CAS:ES 936 is a potent and selective NQO1 inhibitor, inhibiting more than 95% of NQO1 100 nM, with a cell line-dependent inhibition duration.Formula:C18H16N2O6Purity:98%Color and Shape:SolidMolecular weight:356.33AMPA receptor modulator-2
CAS:AMPA receptor modulator-2 is a modulator of AMPA receptor. The pIC50 value for TARPγ2 dependent AMPA receptor is 10.1.
Formula:C15H6F6N4OSPurity:99.8%Color and Shape:SolidMolecular weight:404.29Brivudine monophosphate
CAS:Brivudine monophosphate, a phosphate ester, inhibits DNA repair, induces apoptosis, and may downregulate STAT3 and chemoresistance genes.Formula:C11H14BrN2O8PColor and Shape:SolidMolecular weight:413.12GLX481304
CAS:GLX481304 is a selective Nox-2 and Nox-4 inhibitor, exhibiting IC50 values of 1.25 μM.Formula:C23H29N7OColor and Shape:SolidMolecular weight:419.52ML-090
CAS:ML-090 is NOX1-specific inhibitor(IC50 = 90 nM) which is >100 selectivity for NOX1 over NOX2, NOX3, NOX4 (all IC50s >10 μM).Formula:C14H10N4Purity:98.55%Color and Shape:SolidMolecular weight:234.26Ganciclovir triphosphate
CAS:Ganciclovir triphosphate: synthetic 2'-deoxy-guanosine analog, treats/prevents CMV, IC50 of 0.01 μM, effective across species.Formula:C9H16N5O13P3Color and Shape:SolidMolecular weight:495.17Sorivudine
CAS:Sorivudine (BV-araU) is an antiviral blocking DNA synthesis in viruses like varicella, HSV-1, and Epstein-Barr.Formula:C11H13BrN2O6Purity:99.74%Color and Shape:SolidMolecular weight:349.13Emtricitabine triphosphate
CAS:Emtricitabine triphosphate is an active metabolite of Emtricitabine, a drug for HIV/HBV that inhibits reverse transcriptase.Formula:C8H13FN3O12P3SColor and Shape:SolidMolecular weight:487.19Lobucavir
CAS:Lobucavir (BMS-180194; SQ 34514) is a nucleoside analogue and an antiviral agent with broad-spectrum activity against various viruses, including HBV, HIV/AIDS, and α, β, and γ herpesviruses (including CMV, herpes simplex virus, varicella-zoster virus, and Epstein-Barr virus).
Formula:C11H15N5O3Color and Shape:SolidMolecular weight:265.27
