
Peptides and Proteins
Peptides are short chains of amino acids linked by peptide bonds, whereas proteins are longer and more complex amino acid chains that can adopt functional three-dimensional structures. Both types of compounds are essential for various biological functions, such as catalysing reactions (enzymes), immune defence (antibodies), and cellular signalling. Proteins have a hierarchical structure, including the amino acid sequence, secondary, tertiary, and quaternary structures. Peptides are used in pharmaceutical and cosmetic therapies due to their specific biological properties, such as in the treatment of metabolic diseases or enhancing cellular regeneration. Proteins, on the other hand, have applications in biotechnology, nutrition, and regenerative medicine.
At CymitQuimica, we offer high-purity peptides and proteins for research in biotechnology and therapeutic applications.
Found 3129 products of "Peptides and Proteins"
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Cyclosporin H
CAS:<p>Applications Cyclosporin is an immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection.A group of nonpolar cyclic oligopeptides with immunosupppressant activity.<br>References van Wartburg, A., et al.: Prog. Med. Chem., 25, 1 (1988), Jorgensen, K.A., et al.: Scand. J. Imunol., 57, 93 (2003), Vollenbroeker, et al.: Transplant. Proc., 37, 1741 (2005),<br></p>Formula:C62H111N11O12Color and Shape:NeatMolecular weight:1202.61Boceprevir (>90%)
CAS:Controlled ProductFormula:C27H45N5O5Purity:>90%Color and Shape:NeatMolecular weight:519.68Carfilzomib (2R,4S)-Diol
CAS:Controlled Product<p>Applications Carfilzomib (2R,4S)-Diol is a derivative of Carflizomib (C183460), a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.<br>References Fostier, K., et al.: Oncotargets. Therap., 5, 237 (2012); Geurink, P.P., et al.: J. Med. Chem., 56, 1262 (2013); McCormack, P.L., et al.: Drugs., 72, 2023 (2012);<br></p>Formula:C40H59N5O8Color and Shape:NeatMolecular weight:737.93L-Valine-13C5,15N
CAS:Controlled Product<p>Applications Labelled analogue of L-Vailne. L-Valine is an essential amino acid and one of 20 proteinogenic amino acids. L-Valine cannot be manufactured by the body and must be acquired through diet or supplementation. L-valine is found in grains, dairy products, mushrooms, meats, peanuts and soy proteins. L-Valine has been used in studies to attenuate arrhythmias and induce hypotensive effects.<br>References Choi, C.W. et al.: Anim. Feed Sci. Technol., 102, 15 (2002); Kolarski, D. et al.: Krmiva, 30, 155 (1988); Oba, M. et al.: J. Dairy Sci., 93, 2044 (2010); Mitrega, K. et al.: Pharmacol. Res., 64, 218 (2011);<br></p>Formula:C5H1115NO2Color and Shape:NeatMolecular weight:123.1N-Nitroso-D-proline
CAS:Controlled Product<p>Applications A nitrosoamino acid with oncogenic activity. The LD50 of a single ip dose given to Swiss-Webster mice is 203 +/- 22 mg / kg.<br>References Nagasawa, H.T., et al.: J. Med. Chem., 16 (5), 583-585 (1973)<br></p>Formula:C5H8N2O3Color and Shape:NeatMolecular weight:144.13(S)-Lisinopril Dimer
CAS:Controlled Product<p>Applications (S)-Lisinopril (L468985) impurity. Lisinopril Impurity G (Dimer Impurity)<br></p>Formula:C42H60N6O9Color and Shape:WhiteMolecular weight:792.96Bortezomib Trimer
CAS:Controlled Product<p>Applications Bortezomib Trimer is derived from Bortezomib (B675700), which is the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway.<br>References Nawrocki, S.T., et al: Cancer Research, 65, 11510 (2005); Drahl C.: Chem. and Eng. News, 87, 41 (2009)<br></p>Formula:C57H69B3N12O9Color and Shape:NeatMolecular weight:1098.666Methyltetrazine-Amine
CAS:<p>Methyltetrazine-Amine is a methyl-substituted tetrazine amine used in the synthesis of PROTAC molecules.</p>Formula:C10H11N5Purity:97.59%Color and Shape:Pink SolidMolecular weight:201.23Sacubitril-d4
CAS:Controlled Product<p>Applications Isotope labelled Sacubitril is an antihypertensive drug used in combination with Valsartan (V095750). The combination drug, valsartan/sacubitril, known during trials as LCZ696 and marketed under the brand name, Entresto, is a treatment for heart failure.<br>References McMurray, J., et al.: N. Eng. J. Med., 371 (2014);<br></p>Formula:C242H4H25NO5Color and Shape:Light YellowMolecular weight:415.521,2-Bismethylphenidate (Mixture of Diastereomers)
Controlled Product<p>Applications 1,2-Bismethylphenidate is an impurity of methylphenidate (M325880), an CNS stimulant.<br>References Greenblatt, E.N., et al.: J. Pharmacol. Exp. Ther., 131, 115 (1961), Padmanabhan, G.R., Anal. Profiles Drug Subs., 10, 473 (1981), Srinivas, N.R., et al.: Pharm. Res., 10, 14 (1993),<br></p>Formula:C23H27NO4Color and Shape:NeatMolecular weight:381.46(2S,4R)-Sacubitril
CAS:Controlled Product<p>Stability Temperature Sensitive<br>Applications (2S,4R)-Sacubitril is the enantiomer and an impurity of Sacubitril (S080895) which is an antihypertensive drug used in combination with valsartan.<br>References McMurray, J., et al.: N. Eng. J. Med., 371 (2014);<br></p>Formula:C24H29NO5Color and Shape:Colourless To Off-WhiteMolecular weight:411.49Cyclosporin AM 1 (>80%)
CAS:Controlled Product<p>Applications A cyclosporine metabolite specifically inhibits growth of renal cells in culture.<br>References Schultz, J.C.; et al.: Biochem. Pharma., 42, 1403 (1991), Johnson, B., et al.: Drug Metab. Dispos., 34, 556 (2006), Westley, I.S., Drug Metab. Dispos., 36, 46 (2008).<br></p>Formula:C62H111N11O13Purity:>80%Color and Shape:NeatMolecular weight:1218.613,3’,5-Triiodo-L-thyronine
CAS:Controlled ProductFormula:C15H12I3NO4Color and Shape:White To Off-WhiteMolecular weight:650.973,5,3',5'-Tetraiodo Thyroacetamide
CAS:Controlled Product<p>Impurity Levothyroxine Acetamide Impurity<br>Applications 3,5,3',5'-Tetraiodo Thyroacetamide is a thyroid hormone analogue, a Thyroxine (T425600) impurity.<br>References Andre, M., et al.: J. Chromatogr., 741, 146 (1996),<br></p>Formula:C14H9I4NO3Color and Shape:Light Orange Colour To Light BrownMolecular weight:746.84N2-(S)-1-Carboxy-3-phenylpropyl-L-lysine
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Lisinopryl impurity.<br>References Goa, K.L., et al.: Drugs, 52, 564 (1996), Cao, X.J., et al.: J. Pharm. Biomed. Anal., 39, 39 (2005),<br></p>Formula:C16H24N2O4Color and Shape:White To Light BeigeMolecular weight:308.37L-Methionine [R,S]-Sulfoximine
CAS:Controlled Product<p>Applications Methionine sulfoximine inhibits both glutamine synthetase and g-glutamylcysteine synthetase. Working concentrations for inhibition of g-glutamylcysteine synthetase are 0.2-2.0 mM (52% inhibition occured at 100 mM).Methionine sulfoximine is also a toxic byproduct of nitrogen trichloride, a compound that was used to bleach unprocessed wheat flour prior to 1968. The compound has been investigated as a potential neurotoxin linked to diseases such as amyotrophic lateral sclerosis (ALS) and Parkinson’s disease.<br>References Griffith, O.W., and Meister, A.: J. Biol. Chem. 254, 7558 (1979), Willard-Mack, C.L., et al: Neuroscience, 71, 2, 589 (1996)<br></p>Formula:C5H12N2O3SColor and Shape:NeatMolecular weight:180.23Methionine
CAS:<p>Methionine (D-Methionine) (MRX-1024; D-Methionine) is an effective chemoprotective agent which can also inhibit the neuronal activity through GABAA receptor</p>Formula:C5H11NO2SPurity:99.13% - 99.62%Color and Shape:SolidMolecular weight:149.21N-Pyrazinylcarbonyl-L-phenylalanine
CAS:Controlled Product<p>Applications Used for the synthesis of Bortezomib (B675700) from L-phenylalanine via dipeptidyl boronic acid ester intermediates.<br>References Zhu, Y., et al.: J. Med. Chem., 52, 4192 (2009),<br></p>Formula:C14H13N3O3Color and Shape:WhiteMolecular weight:271.27[Des-Thr-ol8]-[D-Cys7]-Octreotide TFA
CAS:Controlled ProductFormula:C45H57N9O9S2•x(C2HF3O2)Color and Shape:NeatMolecular weight:932.1211402Methyl Benzenesulfonate
CAS:Controlled Product<p>Applications A sulfonate ester as potential genotoxic impurity in drug substances. It may exert genotoxic effects in bacterial and mammalian cell systems.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Eder, E., et al.: Xenobiotica, 12, 831 (1982), Li, W., et al.: J. Chromatogr., 1046, 297 (2004), Glowienke, S., et al.: Mutat. Res., 581, 23 (2005), Colon, I., et al.: J. Pharm. Biomed. Anal., 39, 477 (2005),<br></p>Formula:C7H8O3SColor and Shape:ColourlessMolecular weight:172.2

