Salts and Derivatives of Active Pharmaceutical Ingredients (API)
The salts of Active Pharmaceutical Ingredients (APIs) are compounds formed by the reaction of an acid with a base, resulting in an ionic equilibrium. These salts often improve the solubility and stability of APIs, facilitating their absorption in the body. API derivatives are chemical variants of an active ingredient that may have enhanced or modified properties to optimise therapeutic efficacy. API salts are used in the formulation of oral, injectable, and topical medications. Additionally, API derivatives can improve the pharmacokinetics of drugs, such as enabling controlled release of active substances.
At CymitQuimica, we provide API salts and derivatives with the necessary purity and quality for research and pharmaceutical formulation development.
Found 79464 products of "Salts and Derivatives of Active Pharmaceutical Ingredients (API)"
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N1-N2-Di-N-Nitroso methyl (2S,5S)-5-methylpiperazine-2-carboxylate
Formula:C7H12N4O4Molecular weight:216.22,2'-(Thiobis(2-hydroxy-5,1-phenylene))bis(4H-benzo[e][1,3]oxazin-4-one)
CAS:<p>Please enquire for more information about 2,2'-(Thiobis(2-hydroxy-5,1-phenylene))bis(4H-benzo[e][1,3]oxazin-4-one) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Formula:C28H16N2O6SPurity:Min. 95%Molecular weight:508.5 g/mol13-O-Desmethyl tacrolimus
CAS:<p>Tacrolimus is a macrolide immunosuppressant that is used to prevent organ rejection in transplant patients. It binds to the cytosolic protein, FKBP-12, which prevents calcineurin from dephosphorylating and activating nuclear factor of activated T cells (NFAT). Tacrolimus inhibits the production of IL-2 and other cytokines by T cells, suppressing proliferation. Tacrolimus has been shown to be bioequivalent when administered orally or intravenously. Bioavailability may be increased when taken with food.</p>Formula:C43H67NO12Purity:90%MinColor and Shape:PowderMolecular weight:789.99 g/molMetaphit methylsulfate
CAS:<p>Metaphit methylsulfate is a specific PCP antagonist and an acylating agent for the [3H] phencyclidine binding site in rat brain homogenate. It inhibits PCP-induced motor activity through a presynaptic mechanism.</p>Formula:C19H28N2O3S2Color and Shape:SolidMolecular weight:396.567PDE2 inhibitor 6
CAS:<p>PDE2 inhibitor6 (Compound 1) is an orally active phosphodiesterase (PDE) inhibitor, effectively inhibiting PDE2A, PDE3B, and PDE10A2 with IC50 values of 0.95 nM, 6.17 μM (pIC50=5.21), and 87.1 nM (pIC50=7.06), respectively. It modulates AMPA receptor activity, enhances synaptic plasticity, and improves learning and memory in rat models. Furthermore, PDE2 inhibitor6 possesses blood-brain barrier permeability.</p>Formula:C20H22F2N6OColor and Shape:SolidMolecular weight:400.425(RS)-AMPA hydrochloride
CAS:<p>(RS)-AMPA ((±)-AMPA) hydrochloride is a glutamate analog and serves as an efficient selective agonist for the excitatory neurotransmitter L-glutamic acid (L-glutamic acid). It does not interfere with the binding sites of alginate or NMDA receptors.</p>Formula:C7H11ClN2O4Color and Shape:SolidMolecular weight:222.63LY503430
CAS:<p>LY503430: Oral AMPA enhancer with nootropic, neuroprotective properties, mitigates 6-OHDA/MPTP brain damage.</p>Formula:C20H25FN2O3SPurity:98%Color and Shape:SolidMolecular weight:392.49LY 235959
CAS:<p>LY 235959 is a NMDA receptor antagonist.</p>Formula:C11H20NO5PPurity:98%Color and Shape:SolidMolecular weight:277.25Antidepressant agent 9
CAS:<p>Antidepressant agent 9 (Compound 24) is an orally active inhibitor of NMDAR and SERT, with IC50 values of 3.50 μM and 1044 nM, respectively. It exhibits good metabolic stability and plasma exposure, and demonstrates antidepressant-like effects in the forced swim test in mice.</p>Formula:C17H24N2Color and Shape:SolidMolecular weight:256.386Lu AF90103
CAS:<p>Lu AF90103 (Compound 42e) is the methyl ester prodrug of compound 42d, capable of crossing the blood-brain barrier. Compound 42d acts as a partial agonist of the GluN1/GluN2B complex, with an efficacy of 24% and an EC50 value of 78 nM. Lu AF90103 plays a significant role in neuropsychiatric disorder research.</p>Formula:C13H15N3O3SColor and Shape:SolidMolecular weight:293.342EU 1622-240
CAS:<p>EU 1622-240 is an allosteric modulator with a preference for GluN2B, GluN2C, and GluN2D, exhibiting EC50 values of 0.57, 0.82, and 1.1 μM, respectively. It possesses favorable physicochemical properties, along with in vitro stability and permeability.</p>Formula:C20H14BrF2N3O2SColor and Shape:SolidMolecular weight:478.31(RS)-AMPA
CAS:<p>(RS)-AMPA ((±)-AMPA) is a glutamate analog. (RS)-AMPA is an agonist of effective and selective excitatory neurotransmitter L-glutamic acid.</p>Formula:C7H10N2O4Purity:98%Color and Shape:SolidMolecular weight:186.17PF-06462894
CAS:PF-06462894: morpholinopyrimidone, mGlu5 antagonist (Ki=6nM), no immune activation in mouse model.Formula:C18H23N3O3Purity:98%Color and Shape:SolidMolecular weight:329.39(RS)-AMPA hydrobromide
CAS:AMPAR agonistFormula:C7H11BrN2O4Purity:98%Color and Shape:SolidMolecular weight:267.08Caramboxin
CAS:<p>Caramboxin, a neurotoxin, can induce acute kidney injury.</p>Formula:C11H13NO6Color and Shape:SolidMolecular weight:255.22NYX-2925
CAS:<p>NYX-2925, an oral NMDAR modulator, enhances Src in mPFC. No CAMKII impact or addictive/sedative effects. Useful for CNS disorder studies.</p>Formula:C14H23N3O4Color and Shape:SolidMolecular weight:297.35LY 215490
CAS:<p>LY 215490 is a selective AMPA receptor antagonist with neuroprotective properties in rat ischemia.</p>Formula:C13H21N5O2Purity:98%Color and Shape:SolidMolecular weight:279.34NMDA receptor antagonist-3
<p>NMDA antagonist-3: recovery rate 40% at 100 μM, low toxicity in SH-SY5Y, human stem cells.</p>Formula:C13H19N3O6Color and Shape:SolidMolecular weight:313.31(RS)-AMPA monohydrate
CAS:<p>(RS)-AMPA monohydrate, potent glutamate analogue, selectively activates L-glutamic acid without affecting kainic acid or NMDA receptors.</p>Formula:C7H12N2O5Color and Shape:SolidMolecular weight:204.182BMS-986163
CAS:<p>BMS-986163, a prodrug, quickly becomes BMS-986169, a GluN2B inhibitor (Ki=4 nM, IC50=24 nM).</p>Formula:C23H28FN2O5PPurity:98%Color and Shape:SolidMolecular weight:462.453-Methoxy PCE hydrochloride
CAS:<p>3-Methoxy PCE (3-MEO PCE) hydrochloride is an arylcyclohexylamine compound that functions as an NMDA receptor antagonist with a pKi value of 7.22.</p>Formula:C15H24ClNOColor and Shape:SolidMolecular weight:269.81Antidepressant agent 8
CAS:<p>Antidepressant agent 8 (Compound 1f) acts as a selective antagonist for the NMDA receptor GluN1/2A (NMDA receptorGluN1/2A), with an IC50 of 2.94 μmol/L. In a hydrocortisone-induced zebrafish depression model, it demonstrates antidepressant-like effects and shows good blood-brain barrier penetration.</p>Formula:C18H23FN4OS2Color and Shape:SolidMolecular weight:394.53EMD-95885
CAS:<p>EMD-95885 is a selective antagonist of NMDA receptors containing NR2B subunits, with an IC50 of 3.9 nM. It does not interact with other sites on the NMDA receptor.</p>Formula:C22H23FN2O3Color and Shape:SolidMolecular weight:382.428(3S,6R)-NML
CAS:<p>(3S,6R)-NML is an NMDA receptor antagonist with pIC50 values of 4.8 [GluN1-GluN2A], 4.6 [GluN1-GluN2B], 5.0 [GluN1-GluN2C], and 5.0 [GluN1-GluN2D]. It is applicable in the study of depression.</p>Formula:C20H27NOColor and Shape:SolidMolecular weight:297.435Tamitinol
CAS:<p>Tamitinol is a neurotropic drug. It has been found to help symptoms of obsessive rumination in conjunction with maprotiline.</p>Formula:C12H20N2OSPurity:98%Color and Shape:SolidMolecular weight:240.37LY3130481
CAS:<p>LY3130481: TARP γ-8 dependent AMPA receptor blocker; selectively targets AMPA/TARP γ-8 with 65 nM IC50.</p>Formula:C19H18N4O3SColor and Shape:SolidMolecular weight:382.44YY-23
CAS:<p>YY-23 is a selective NMDAR (containing GluN2C or GluN2D) inhibitor. By inhibiting NMDARs with GluN2D on GABAergic interneurons in the prefrontal cortex, YY-23 suppresses GABAergic neurotransmission and enhances excitatory transmission. YY-23 exhibits antidepressant activity and is useful for neurological disease research.</p>Formula:C33H54O8Color and Shape:SolidMolecular weight:578.777Caged MK801
CAS:<p>Caged MK801 (cMK801) is a selective, noncompetitive, and irreversible blocker of the NMDA receptor open channel. The NVOC cage is compatible in neuropharmacology and does not alter the intrinsic activity of the molecule.</p>Formula:C26H24N2O6Color and Shape:SolidMolecular weight:460.48Perfluoroheptanesulfonic acid
CAS:<p>Perfluoroheptanesulfonic acid (1-Perfluoroheptanesulfonic acid; Perfluoroheptanesulphonic acid) is a perfluoroalkyl substance (PFAS). This compound has been detected in landfill leachate and has been shown to induce deformities in zebrafish larvae (EC50=168.1 μM). Exposure to PFHpS in fetuses can lead to reduced birth weight.</p>Formula:C7HF15O3SColor and Shape:SolidMolecular weight:450.12Blixeprodil
CAS:<p>Blixeprodil (GM-1020) is an orally active NMDA receptor antagonist with an affinity of Ki = 3.25 µM in rat cortical tissue. It inhibits NR1/2A-NMDAR-mediated currents in HEK293 cells with an IC50 of 1.192 µM. Blixeprodil demonstrates antidepressant effects in rat models and exhibits blood-brain barrier permeability.</p>Formula:C13H16FNOColor and Shape:SolidMolecular weight:221.271NMDA agonist 1
CAS:<p>NMDA agonist 1 (compound 42d) is a potent NMDA agonist with a Ki value of 96 nM. It acts as a partial agonist of the GluN1/GluN2B complex, exhibiting an EC50 value of 78 nM.</p>Formula:C12H13N3O3SColor and Shape:SolidMolecular weight:279.315Onfasprodil
CAS:<p>Onfasprodil, NR2B inhibitor & GABA regulator, potential for Alzheimer's research. (Patent CN111481543A)</p>Formula:C20H23FN2O3Color and Shape:SolidMolecular weight:358.41Macitentan (n-butyl analogue)
CAS:<p>Macitentan n-butyl analogue, an oral ETA/ETB receptor blocker, may treat IPF and PAH.</p>Formula:C20H21Br2N5O4SPurity:98%Color and Shape:SolidMolecular weight:587.29DL-AP5 lithium
CAS:<p>DL-AP5 (2-APV) lithium is a competitive antagonist of the NMDA (N-Methyl-D-aspartate) receptor. It exhibits notable analgesic activity and specifically blocks channels in the rabbit retina.</p>Formula:C5H11LiNO5PColor and Shape:SolidMolecular weight:203.06SDZ 220-040
CAS:<p>SDZ 220-040 是一种选择性哺乳动物 NMDA 受体拮抗剂，可诱导根系生长的部分无重力模式 。</p>Formula:C16H16Cl2NO6PPurity:98.13%Color and Shape:SolidMolecular weight:420.18BDZ-g
CAS:BDZ-g: potent, selective AMPA receptor antagonist; useful for researching neurological disorders.Formula:C21H21N5O2SPurity:99.97%Color and Shape:SolidMolecular weight:407.49tert-Butyl Hydrogen Tetradecanedioate
CAS:Formula:C18H34O4Purity:>95.0%(GC)(T)Color and Shape:White to Light yellow powder to crystalMolecular weight:314.474,4'-Diethynylbiphenyl
CAS:Formula:C16H10Purity:>98.0%(GC)Color and Shape:White to Light yellow to Light orange powder to crystalMolecular weight:202.26D-2-Phenylglycine
CAS:Formula:C8H9NO2Purity:>99.0%(T)Color and Shape:White to Almost white powder to crystalMolecular weight:151.17Veratramine
CAS:Formula:C27H39NO2Purity:>98.0%(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:409.614-Maleimidobutyric Acid
CAS:Formula:C8H9NO4Purity:>98.0%(GC)Color and Shape:White to Almost white powder to crystalMolecular weight:183.16(1E,4E)-1,5-Bis[3,5-bis(methoxymethoxy)phenyl]-1,4-pentadiene-3-one
CAS:Formula:C25H30O9Purity:>97.0%(HPLC)Color and Shape:White to Yellow to Green powder to crystalMolecular weight:474.51Isobutyryl Chloride
CAS:Formula:C4H7ClOPurity:>98.0%(GC)(T)Color and Shape:Colorless to Light yellow clear liquidMolecular weight:106.55Ref: ST-EA-CP-D73001
Discontinued productIscotrizinol Related Compound G (2-Ethylhexyl 4-{4-[(4-{[4-(tert-butylcarbamoyl)phenyl]amino}-6-[(4-{[(2-ethylhexyl)oxy]carbonyl}phenyl)amino]-1,3,5-triazin-2-yl)amino]benzamido}benzoate) (DISCONTINUED)
Compounds (excluding melamine) containing an unfused triazine ring (whether or not hydrogenated) in the structureFormula:C51H64N8O6Color and Shape:PowderMolecular weight:884.49488Zalcitabine Related Compound A (2',3'-Didehydro-2',3'-dideoxycytidine) (DISCONTINUED)
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormula:C9H11N3O3Color and Shape:PowderMolecular weight:209.23Ioversol Related Compound A (5-Amino-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide) (DISCONTINUED)
CAS:Aromatic cyclic amides (including cyclic carbamates) and their derivatives; salts thereofFormula:C14H18I3N3O6Color and Shape:Off-White Tan Crystalline PowderMolecular weight:704.83298Proguanil Related Compound C (1,5-bis(4-chlorophenyl)biguanide hydrochloride)
CAS:Aromatic imines and their derivatives, salts thereofFormula:C14H13Cl2N5·HClColor and Shape:White Crystalline PowderMolecular weight:321.0548Gadoversetamide Related Compound A (DISCONTINUED)
Compounds, inorganic or organic, of rare-earth metals, of yttrium or of scandium, or of mixtures of these metals, excluding cerium compounds, nesoiFormula:C17H27N4O10GdColor and Shape:White PowderMolecular weight:604.67Drometrizole Trisiloxane Related Compound E (2-(2H-Benzotriazol-2-yl)-6-{3-[bis(trimethylsiloxy)methylsilyl]isobutyl}-O1-[bis(trimethylsiloxy)methylsilyl]-p-cresol) (DISCONTINUED)
CAS:Aromatic or modified aromatic drugs with nitrogen heterFormula:C31H59N3O5Si6Color and Shape:Pale Yellow LiquidMolecular weight:722.33Pamabrom Related Compound A (8-Chlorotheophylline) (DISCONTINUED)
CAS:Theophylline and aminophylline (excluding fenetylline) and their derivatives, salts thereof, not elsewhere specified or includedFormula:C7H7ClN4O2Color and Shape:PowderMolecular weight:214.02575
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