Sulfonamides and Derivatives
Sulphonamides are compounds that contain a sulphonamide functional group (-SO₂NH₂), where a sulphur atom is bonded to an amino group. They were among the first synthetic antibiotics used in medicine, inhibiting folic acid synthesis in bacteria, which gives them antimicrobial properties. They are mainly used to treat bacterial infections, although their use has declined due to antimicrobial resistance. In addition to their use as antibiotics, sulphonamides also have applications in the treatment of diseases such as malaria and inflammatory bowel diseases.
At CymitQuimica, we offer high-purity sulphonamides and their derivatives for research in microbiology and pharmaceutical development.
Found 2584 products of "Sulfonamides and Derivatives"
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Ibuprofen Ethyl Ester
CAS:Controlled Product<p>Applications Ibuprofen Ethyl Ester is a derivative of Ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID) that is known to inhibit PGH synthase-1 and PGH synthase-2 with comparable potency.<br>References Gnanarajan, G., et al.: Int. J. Pharma. Sci. Rsch., 1, 27 (2010); Busson, M., et al.: J. Int. Med Res., 14, 53 (1986); Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993); Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998);<br></p>Formula:C15H22O2Color and Shape:Colourless To Light YellowMolecular weight:234.33Indomethacin 1-Menthol ester
CAS:Controlled Product<p>Applications Indomethacin terpenoids' esters were synthesized and assessed both in vitro and in vivo as indomethacin dermal prodrugs.<br>References Bonina,, Francesco. , et al.: European Journal of Pharmaceutical Sciences, 14, 123 (2001),<br></p>Formula:C29H34ClNO4Color and Shape:NeatMolecular weight:496.038N-Des(5-methylpyrazinecarbonyl)-N-ethylcarboxyl Glipizide
CAS:Controlled Product<p>Impurity Glipizide EP Impurity C<br>Applications N-Des(5-methylpyrazinecarbonyl)-N-ethylcarboxyl Glipizide (Glipizide EP Impurity C) is an impurity of Glipizide (G410225).<br></p>Formula:C18H27N3O5SColor and Shape:NeatMolecular weight:397.496-Methylpyrazinecarboxylic Acid
CAS:Controlled Product<p>Applications 6-Methylpyrazinecarboxylic Acid can be used to synthesize compounds that are active against M.tuberculosis H37Rv. Similarly, it can be used to synthesize compounds that are useful for the inhibition, prevention or therapy of tumor cell invasion, metastasis, inflammation, hepatitis, or liver dysfunction.<br>References Vontor, T., et al.: Cesk. Farm., 34, 441 (1985); Oka, K., et al.: Jpn. Kokai Tokkyo Koho, JP 2007210926 A 20070823 (2007)<br></p>Formula:C6H6N2O2Color and Shape:NeatMolecular weight:138.12(4-Trideuteromethoxy) Trimethoprim N1-Oxide, ~90%
CAS:Controlled ProductFormula:C14H15D3N4O4Purity:~90%Color and Shape:NeatMolecular weight:309.34Indomethacin Ethyl Ester
CAS:Controlled ProductFormula:C21H20ClNO4Color and Shape:Off-WhiteMolecular weight:385.84Ibuprofen-13C6
CAS:<p>Applications Labelled Ibuprofen, a selective cyclooxygenase inhibitor (IC50=14.9uM). Inhibits PGH synthase-1 and PGH synthase-2 with comparable potency.<br>References Busson, M., et al.: J. Int. Med Res., 14, 53 (1986), Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993), Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998),<br></p>Formula:C713C6H18O2Color and Shape:NeatMolecular weight:212.24trans-Carboxy Glimepiride-d5
CAS:Controlled Product<p>Applications An active labelled metabolite of Glimepiride (G410150).<br>References Groop, L., et al.: Diabetes Care, 15, 737 (1992), Muller, G., et al.: Diabetes, 42, 1852 (1993), Kramer, W., et al.: Biochem. Biophys. Acta, 119, 278 (1994),<br></p>Formula:C24H27D5N4O7SColor and Shape:NeatMolecular weight:525.63Gliclazide Impurity D
CAS:<p>Applications Gliclazide Impurity D is a manufacturing impurity of the drug Gliclazide (G409875) which is a sulfonylurea hypoglycemic agent and is used as an antidiabetic.<br>References Duhault, J., et al.: Arzneimittel-Forsch., 22, 1686 (1972), Holmes, B., et al.: Drugs, 27, 301 (1984),<br></p>Formula:C15H20N2O3SColor and Shape:NeatMolecular weight:308.3959Ethyl 4-[2-(5-Chloro-2-methoxybenzamido)ethyl]benzene Sulfonamide Carbamate
CAS:Controlled ProductFormula:C19H21ClN2O6SColor and Shape:NeatMolecular weight:440.90N-Acetyl Dapsone-d8 (Major)
CAS:Controlled Product<p>Applications A labelled metabolite of Dapsone (D193250).A representative lot is 73% d8, 23% d7 and 3% d6 with no d0.<br>References Shin, I., et al.: J. App. Pharmacol., 10, 193 (2002), Bhaiya, P., et al.: Toxicol. App. Pharmacol., 215, 158 (2006), Paixao, P., et al.: Eur. J. Pharm. Sci., 36, 544 (2009),<br></p>Formula:C14H6D8N2O3SColor and Shape:NeatMolecular weight:298.392-Chloro-5-(1-ethoxy-3-oxoisoindolin-1-yl)benzenesulfonamide
CAS:Controlled Product<p>Applications Ethyl Chlorthalidone is an impurity of Chlorthalidone (C427500). Chlorthalidone is used as a diuretic; an antihypertensive.<br>References Beisenherz, et al.: Arch. Int. Pharmacodyn. Ther., 161, 76 (1966), Zsoter, et al.: J. Pharmacol. Exp. Ther., 180, 723 (1972), Singer, J.M., et al.: Anal. Profiles Drug Subs., 14, 1 (1985),<br></p>Formula:C16H15ClN2O4SColor and Shape:Off WhiteMolecular weight:366.82rac trans-Hydroxy Glimepiride-d5
CAS:Controlled Product<p>Applications An active metabolite of Glimepiride.<br>References Muller, G., et al.: Diabetes, 42, 1852 (1993), Kramer, W., et al.: Biochem. Biophys. Acta, 119, 278 (1994),<br></p>Formula:C24H29D5N4O6SColor and Shape:NeatMolecular weight:511.651,2-Benzisoxazol-3-ylacetic Acid
CAS:Controlled Product<p>Applications 1,2-Benzisoxazol-3-ylacetic Acid is a synthetic auxin and an intermediate in the synthesis of Zonisamide (Z700000).<br>References Branca, C., et al.: Plant Cell Tiss. Org., 21, 17 (1990); Branca, C., et al.: Plant Cell Rep., 12, 121 (1993)<br></p>Formula:C9H7NO3Color and Shape:NeatMolecular weight:177.16Indomethacin Acyl-β-D-glucuronide (>90%)
CAS:Controlled Product<p>Applications Indomethacin Acyl-β-D-glucuronide is a metabolite of Indomethacin (I641000). Acyl glucuronides have been implicated in the toxicity of many xenobiotics and marketed drugs.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Abid, A., et al.: Biochem. Pharmacol., 50, 557 (1995), Gamage, N., et al.: Toxicol. Sci., 90, 5 (2006), Cerveny, L., et al.: Drug Metab. Dispos., 35, 1032 (2007), Hayeshi, R., et al.: Eur. J. Pharm. Sci., 35, 383 (2008),<br></p>Formula:C25H24ClNO10Color and Shape:NeatMolecular weight:533.912'-Phenoxymethanesulfonanilide
CAS:Controlled ProductFormula:C13H13NO3SColor and Shape:White To Off-WhiteMolecular weight:263.31
![Ethyl 4-[2-(5-Chloro-2-methoxybenzamido)ethyl]benzene Sulfonamide Carbamate](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTR%2Fthumb-webp%2FE901960.webp&w=3840&q=75)
