APIs for research and impurities

FR183998 is an anticancer drug that is derived from Chinese urine. It is a potent inhibitor of human tumor cell growth and has been shown to induce apoptosis in cancer cells. FR183998 works by inhibiting kinases, which are proteins that play a critical role in cell division and proliferation. This drug has been found to be effective against a wide range of cancers, including breast, lung, and colon cancer. Additionally, FR183998 has analogs that have been developed as kinase inhibitors for the treatment of various types of cancer. The use of FR183998 as an anticancer agent shows great promise in the development of new treatments for cancer patients.

Please enquire for more information about 4'-Bromo-2-(diethylamino)-2',6'-acetoxylidide including the price, delivery time and more detailed product information at the technical inquiry form on this page

Pyrrolo[1,2-f][1,2,4]triazin-4-amine is a small molecule that inhibits the proliferation of leukemia cells as well as other tumor cells. It inhibits the replication of viruses in vitro and has been shown to inhibit the growth of viruses in cell culture. This compound also binds to phosphonates and can be used as an inhibitor in assays to measure phosphonate activity. Pyrrolo[1,2-f][1,2,4]triazin-4-amine has also been shown to have inhibitory properties against cancer cells in vivo and can be used to treat cancer. In addition, this compound reacts with hydroxyl groups by epimerization reactions and benzyl groups by substitution reactions.

Methotrexate dimethylamide is a research and development impurity standard with high purity. It is a synthetic drug product that can be custom synthesized to meet the needs of the customer. Methotrexate dimethylamide has been used as an analytical standard for HPLC analysis and as a natural metabolite in metabolism studies. This compound is also known as 71074-44-7, CAS No. 71074-44-7, or Metabolite.

Alloc bromoridane is a drug product that contains the active ingredient bromoridane. Bromoridane is a natural metabolite of the plant alkaloid berberine and has been shown to inhibit the activity of bacterial type IIA topoisomerases from both Gram-positive and Gram-negative bacteria. The chemical name for Alloc bromoridane is 2-[2-(4-bromobenzoyl)phenyl]dihydropyrimidine, and it has CAS number 117348-70-6. Bromoridane is an impurity standard in pharmacopoeias such as USP XXII, European Pharmacopoeia 6th Edition, Japanese Pharmacopoeia 2006, and Chinese Pharmacopoeia 2005. Alloc bromoridane is used in research and development for pharmaceuticals or as an analytical reference material.

(Z)-Fluvoxamine-EP is a drug product that is used as an analytical standard. It is a synthetic metabolite of fluvoxamine, which is a drug used for the treatment of depression. The synthesis of (Z)-fluvoxamine-EP is based on the asymmetric synthesis of fluvoxamine and the use of chiral chromatography to purify the product. This synthetic process allows for the production of high-purity (Z)-fluvoxamine-EP with a purity greater than 99%.

Please enquire for more information about 3’-o-Desmethyl aliskiren hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Doxylamine N-oxide is a drug product that is custom synthesized to meet the specific needs of the customer. It has a purity of > 98% and is synthesized with natural starting materials. Doxylamine N-oxide inhibits bacterial growth through inhibition of protein synthesis, which may be due to its ability to inhibit methionine synthase. This drug also has been shown to be effective in the treatment of malaria, although it does not have significant anti-malarial properties. Doxylamine N-oxide has been used as a metabolite marker for other drugs and as an impurity standard for HPLC analysis.

Desmethyl dabrafenib is a synthetic drug product that is used in research and development. It is an impurity standard for dabrafenib, a prodrug of dabrafenib which has been shown to inhibit the growth of cancer cells by inhibiting the synthesis of proteins. Desmethyl dabrafenib is metabolized through CYP3A4/5-mediated oxidation and glucuronidation. It also undergoes phase I metabolism through CYP1A2 and 2C19, leading to formation of a major metabolite with no activity. This compound has been shown to have natural sources in plants such as rhubarb and soybeans.

(6R)-Folinic acid is an impurity standard and a metabolite of folic acid. It is synthesized by the body in the liver, where it is converted to 5,10-methylenetetrahydrofolate (5,10-MTHF). This metabolite is used to convert homocysteine into methionine, which can then be converted into S-adenosylmethionine (SAMe), a compound that has been shown to have antidepressant properties. The methylation of folate also helps to regulate DNA synthesis and repair. (6R)-Folinic acid has been used in research as a drug development tool for studying folate metabolism and its effects on the central nervous system. High purity standards are available for use in HPLC analysis of this compound.

Impurity A is an impurity of the drug product, dexamethasone. The impurity is a natural metabolite of dexamethasone that is found in the urine of patients taking this medication. Impurity A is chemically identified using HPLC and its purity verified using GC-MS and LC-MS. This impurity can be used as a reference standard for analytical purposes and as an impurity standard for pharmacopoeia testing.

O-Acetyl silodosin is a synthetic, natural metabolite of silodosin. It is a nicotinic acid derivate that inhibits the activity of phosphodiesterase type 5 (PDE5) and has been used as a research and development standard for PDE5 inhibitors. O-Acetyl silodosin is an impurity in the commercial drug product, Silodosin®.

Please enquire for more information about Hydrocortisone 17-valerate 21-acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Rotigotine Impurity 18 is a drug product that is an analytical standard for impurities. It is a synthetic impurity that is not found in natural sources. Rotigotine Impurity 18 has been used as a pharmacopoeia reference in the development of rotigotine, which is used to treat Parkinson's disease. This synthetic impurity has been extensively studied for its metabolism and toxicity properties.

Dispersants are substances that are used to break up and disperse particles in a liquid. The dispersant 11-[3-(dimethylamino)propyl]-6,11-dihydrodibenz[b,e]oxepin-11-ol is an active substance that is used in the production of granules, tablets or other solidified forms of medicaments. It is a substance that has a physiologically active effect on humans and animals. This product can be applied as droplets or particles.

Dioctyl carbonate is a pharmaceutical preparation used to treat skin conditions. It is a fatty acid ester of carbonic and carbonyl groups in which the two esters are in the same molecule. Dioctyl carbonate is a reaction product obtained by reacting an inorganic acid, such as hydrochloric acid or sulfuric acid, with an alcohol containing two hydroxyl groups and one double bond. This reaction may be facilitated by heating. The film-forming polymer may be polyvinylpyrrolidone, polyvinyl alcohol, or polyacrylic acid. Dioctyl carbonate has been shown to stimulate colony-stimulating factor production and inhibit the proliferation of human epidermal keratinocytes.

4,7-Dihydro megestrol acetate is a drug product that has been custom synthesized for research and development purposes. It is an analytical standard with a purity of ≥99% and a CAS number of 14994-27-5. Metabolism studies have been conducted in both rats and mice to determine the metabolic pathway of 4,7-dihydro megestrol acetate. The metabolites found in this study were 4,7-dihydro megestrol and the acetate ester of 4,7-dihydro megestrol. Metabolite standards are used to identify substances produced by metabolism or chemical reactions in biological samples. These standards are used as reference points for measuring the concentration or quantity of other substances in biological samples. Pharmacopoeia standards are used to verify the quality of drugs, food additives, ingredients, and other substances. They also serve as reference points for identifying impurities in substances that may be harmful

5-O-Desethyl amlodipine is a metabolite of amlodipine. It has been used as an analytical reference standard for the determination of amlodipine and its metabolites in human plasma and urine. 5-O-Desethyl amlodipine has been reported to be excreted in human breast milk at a concentration that is about 20% of that found in maternal plasma. The drug product is manufactured by HPLC and is classified as a high purity pharmaceutical drug, which means it is free from extraneous substances such as other drugs, proteins, or bacteria.

Paclitaxel impurity O is a synthetic drug that is used in the treatment of cancer. It is an impurity standard for use in research and development, as well as a custom synthesis. Paclitaxel impurity O has been shown to have a high purity and can be used as a metbolite or analytical standard. It has been shown to possess anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis.