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APIs for research and impurities

APIs for research and impurities

Active Pharmaceutical Ingredients (APIs) are the substances in drugs responsible for their therapeutic effects. In this section, you will find a wide variety of APIs intended for research use. These compounds are essential for the development, testing, and validation of new pharmaceutical formulations. CymitQuimica offers high-quality APIs to support research in drug discovery and development.

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Found 66870 products of "APIs for research and impurities"

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  • Epirubicin impurity G

    CAS:
    Epirubicin impurity G is a synthetic research and development impurity standard that is used in the manufacture of drug products, as well as in the development of new drugs. Epirubicin impurity G is a metabolite of epirubicin and has been shown to be an active inhibitor of DNA synthesis. Epirubicin impurity G may also have potential as an analytical standard for HPLC analysis.
    Formula:C54H58N2O22
    Purity:Min. 95%
    Molecular weight:1,087 g/mol

    Ref: 3D-FE180897

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  • Desethyl amiodarone hydrochloride

    CAS:
    Amiodarone hydrochloride is an antiarrhythmic drug that belongs to the class of chromatographic agents. It is a prodrug, which is metabolized to amiodarone in vivo. Amiodarone has been shown to be effective in preventing ventricular fibrillation and malignant arrhythmias. Amiodarone prevents the onset of cardiac arrhythmia by prolonging the action potential duration and refractory period, which stabilizes the cell membrane potential during depolarization. The drug also inhibits the release of calcium ions from the sarcoplasmic reticulum, thereby reducing excitability and preventing re-entry into a fibrillating state. Amiodarone is used for the treatment of atrial fibrillation, ventricular tachycardia, and chronic heart failure.
    Formula:C23H25I2NO3•HCl
    Purity:Min. 95%
    Color and Shape:Powder
    Molecular weight:653.72 g/mol

    Ref: 3D-ID21171

    2mg
    211.00€
    5mg
    383.00€
    10mg
    543.00€
    25mg
    834.00€
    50mg
    1,207.00€
  • D-Gln19-Tirzepatide


    Tirzepatide impurities.

    Formula:C225H348N48O68
    Molecular weight:4,813.5 g/mol

    Ref: 3D-IG23656

    1mg
    518.00€
    10mg
    2,574.00€
    100mg
    7,721.00€
  • 2,2-Bis(N-(a,a,a-trifluoro-m-tolyl)antranililoxi)diethylether

    CAS:
    2,2-Bis(N-(a,a,a-trifluoro-m-tolyl)antranililoxi)diethylether is a natural compound that is an impurity in the drug 2,2-Bis(N-(a,a,a-trifluoro-m-tolyl)antranilic acid). It has been used as an analytical reference material and as a standard for HPLC. The synthesis of this compound has not been reported. It has been shown to be metabolized by hydrolysis to form 2-(4'-aminophenyl)-3H-[1]benzopyran and benzeneacetic acid. 2,2-Bis(N-(a,a,a-trifluoro-m-tolyl)antranililoxi)diethylether is also known as bis(4'-aminophenyl)-3H-[1
    Formula:C32H26F6N2O5
    Purity:Min. 95%
    Color and Shape:Slightly Yellow Yellow Clear Liquid
    Molecular weight:632.55 g/mol

    Ref: 3D-IB58091

    50mg
    281.00€
    100mg
    422.00€
    250mg
    1,259.00€
    500mg
    1,675.00€
    1g
    2,452.00€
  • N,N'''-(Dithia-2,1-ethanediyl)bis-(N'-cyano-N''-methyl)guanidine

    CAS:

    N,N'''-(Dithia-2,1-ethanediyl)bis-(N'-cyano-N''-methyl)guanidine is a metabolite of guanidine. It is a synthetic compound that is used as an analytical reference standard and impurity in pharmaceutical products. It is also used to create an impurity standard for HPLC analysis. This compound has been found in natural sources such as plants and animal tissues, but it can also be synthesized in the lab. The CAS number for this substance is 74886-59-2.

    Formula:C10H18N8S2
    Purity:Min. 95%
    Color and Shape:White Powder
    Molecular weight:314.43 g/mol

    Ref: 3D-ID58189

    50mg
    225.00€
    100mg
    371.00€
    200mg
    564.00€
    500mg
    2,052.00€
  • Atorvastatin impurity F

    CAS:

    Atorvastatin impurity F is an impurity that can be found in atorvastatin. It is a white to off-white crystalline solid with a melting point of 142°C. It has a molecular weight of 273.5 and chemical formula of C14H13N3O2. This impurity can be found in atorvastatin as an API impurity, which may have an effect on the efficacy or toxicity of the drug product. Impurities are present in all pharmaceutical products and should be identified, characterized, and quantified for quality control purposes. Impurities are often unavoidable byproducts of the manufacturing process and can lead to potential safety concerns if they are not detected early on during drug development. The presence of impurities may also affect the pharmacological effects or therapeutic efficacy of the drug product.

    Formula:C40H47FN3O8Na
    Purity:Min. 95%
    Color and Shape:Powder
    Molecular weight:739.8 g/mol

    Ref: 3D-FA165540

    1mg
    322.00€
    2mg
    494.00€
    5mg
    887.00€
    10mg
    1,381.00€
    25mg
    2,761.00€
  • N-Desmethyl galanthamine

    Controlled Product
    CAS:

    N-Desmethyl galanthamine is a plant alkaloid that is found in the Huperzia serrata plant. It has been shown to have cholinergic activity and calcium binding properties. N-Desmethyl galanthamine inhibits acetylcholinesterase, an enzyme responsible for the breakdown of acetylcholine, which is a neurotransmitter. This inhibition leads to increased levels of acetylcholine, which results in increased neuron stimulation and improved memory function. N-Desmethyl galanthamine also binds to β2 nicotinic receptor sites and blocks the binding of nicotine, leading to decreased nicotine dependence.

    Formula:C16H19NO3
    Purity:Min. 95%
    Molecular weight:273.33 g/mol

    Ref: 3D-ID21271

    1mg
    157.00€
    2mg
    215.00€
  • (1R,3S,5S)-8-Methyl-8-azabicyclo[3.2.1]oct-6-en-3-yl-2'-hydroxy-2',2'-di(thiophen-2''-yl)acetate

    CAS:
    Tanshinone IIA is an enantioselective hydroxamic acid that inhibits matrix metalloproteinase. It is a structural analogue of the hydroxamic acid Tanshinone I and has been shown to inhibit aggrecanase, which is an enzyme that hydrolyzes the glycosaminoglycan aggrecan. It also has anti-cancer effects due to its inhibition of cell proliferation in cancer cells. Tanshinone IIA can be used as a chiral synthon for polymerase chain reactions (PCR) because it contains a stereogenic centre in its structure.
    Formula:C18H19NO3S2
    Purity:Min. 95%
    Color and Shape:Powder
    Molecular weight:361.48 g/mol

    Ref: 3D-IM42883

    25mg
    257.00€
    50mg
    384.00€
    100mg
    601.00€
    250mg
    1,067.00€
    500mg
    1,526.00€
  • Dehydroxy bisoprolol

    CAS:

    Dehydroxy bisoprolol is an impurity of the drug Bisoprolol that is used to make the drug product Metoprolol. It is a metabolite of Bisoprolol, which is produced by the liver after metabolism and excretion. Dehydroxy bisoprolol has been detected in plasma, urine, feces, and breast milk. The pharmacological effects of Dehydroxy bisoprolol have not been studied.

    Formula:C18H29NO3
    Purity:Min. 95%
    Color and Shape:Powder
    Molecular weight:307.43 g/mol

    Ref: 3D-FD20967

    1mg
    332.00€
  • Des-His(1)-Semaglutide


    Des-His(1)-semaglutide is a semaglutide-related impurity. This des-amino acid form has the histidine (His) amino acid from position 1 removed from the peptide chain. Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist used for managing type 2 diabetes and obesity.
    Formula:C181H284N42O58
    Molecular weight:3,976.5 g/mol

    Ref: 3D-IH11729

    1mg
    471.00€
    10mg
    2,340.00€
    100mg
    7,020.00€
  • D-Asp(9)-Tirzepatide


    Tirzepatide impurity.
    Formula:C225H348N48O68
    Color and Shape:Powder
    Molecular weight:4,813.5 g/mol

    Ref: 3D-IA11852

    1mg
    518.00€
    10mg
    2,574.00€
    100mg
    7,721.00€
  • D-Ser(8)-Semaglutide


    D-Ser(8)-Semaglutide is a semaglutide impurity. The amino acid at position 8 has been replaced by the D-form of the amino acid D-serine (D-Ser). Semaglutide impurities are structurally related compounds that arise during synthesis, purification, or storage of semaglutide, a long-acting GLP-1 receptor agonist for managing type 2 diabetes and obesity.
    Formula:C187H291N45O59
    Molecular weight:4,113.64 g/mol

    Ref: 3D-IS27847

    1mg
    471.00€
    10mg
    2,340.00€
    100mg
    7,020.00€
  • Aztreonam impurity D

    CAS:
    Aztreonam impurity D is a metabolite of aztreonam. Aztreonam impurity D is an impurity standard for the pharmacopoeia and API industry, as well as for drug development and research. It has been shown that this compound inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Aztreonam impurity D also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.
    Formula:C13H17N5O5S
    Purity:Min. 95 Area-%
    Color and Shape:Powder
    Molecular weight:355.37 g/mol

    Ref: 3D-IA167738

    1mg
    188.00€
    2mg
    274.00€
    5mg
    491.00€
    10mg
    673.00€
    25mg
    1,142.00€
  • 3-O-Methyl L-DOPA monohydrate

    Controlled Product
    CAS:
    3-O-Methyl L-DOPA monohydrate is a chromatographic method that is used to diagnose Parkinson's disease. The method separates the catechol-o-methyltransferase (COMT) from plasma samples, which converts dopamine to 3-O-methyl dopamine. The 3-O-methyl dopamine reacts with an electrochemical detector and overlapped peaks can be seen on the chromatogram. This analytical method can be used to detect low levels of dopamine in the blood and diagnose Parkinson's disease.
    Formula:C10H13NO4·H2O
    Purity:Min. 95%
    Color and Shape:White Powder
    Molecular weight:229.23 g/mol

    Ref: 3D-FM25519

    30mg
    444.00€
    50mg
    639.00€
    100mg
    1,075.00€
    250mg
    2,453.00€
    500mg
    3,042.00€
  • Terbinafine dimer impurity dihydrochloride

    CAS:

    Terbinafine is an antifungal agent that belongs to the family of medicines. It is used to treat fungal infections of the skin, nails and scalp. Terbinafine can also be used to treat other types of fungal infections, such as tinea corporis (ringworm), tinea cruris (jock itch), tinea pedis (athlete's foot) and tinea capitis (scalp ringworm). Terbinafine dimer impurity dihydrochloride is a by-product of terbinafine hydrochloride that has been shown to have industrial applications as a dispersant or lubricant in industries such as papermaking.

    Formula:C36H40N2·2HCl
    Purity:Min. 95%
    Color and Shape:White Off-White Powder
    Molecular weight:573.64 g/mol

    Ref: 3D-ID28037

    2mg
    327.00€
    5mg
    459.00€
    10mg
    678.00€
    25mg
    1,357.00€
    50mg
    2,345.00€
  • (RS)-Isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(4-nitrophenyl)pyridine-3,5-dicarboxylate

    CAS:
    (RS)-Isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(4-nitrophenyl)pyridine-3,5-dicarboxylate is a white to off-white crystalline powder that is soluble in methanol and slightly soluble in water. It can be used as an impurity standard for the API drug product, research and development and metabolism studies. The CAS number for this compound is 2200280-99-3. This compound has a purity of 99% or greater with an analytical purity of 99.9%. This compound has been shown to have a melting point of about 237°C and a density of 1.06 g/cm3. This compound is insoluble in ether and acetone.
    Formula:C21H26N2O7
    Purity:Min. 95%
    Color and Shape:Light (Or Pale) Yellow To Yellow Solid
    Molecular weight:418.44 g/mol

    Ref: 3D-II57939

    250mg
    134.00€
    500mg
    159.00€
    1g
    470.00€
  • N-[(1R)-1-(1-Naphthalenyl)ethyl]carbamic acid 3-[3-(trifluoromethyl)phenyl]propyl] ester

    CAS:

    N-[(1R)-1-(1-Naphthalenyl)ethyl]carbamic acid 3-[3-(trifluoromethyl)phenyl]propyl] ester is a drug product. It is a synthetic substance that is used in the development of new drugs and for research and development. This impurity standard is used as an analytical reference in the testing of other compounds. N-[(1R)-1-(1-Naphthalenyl)ethyl]carbamic acid 3-[3-(trifluoromethyl)phenyl]propyl] ester has been shown to be a metabolite of CAS No. 915979-44-1, which is also known as N-[(2S)-2-[[5-[3-(Trifluoromethoxy)phenoxy]-2-pyridinyl]methyl]-2,5-dioxopyrrolidin-1-yl]-3,

    Formula:C23H22F3NO2
    Purity:Min. 95%
    Color and Shape:Colorless to yellow liquid.
    Molecular weight:401.42 g/mol

    Ref: 3D-IN58184

    100mg
    140.00€
    250mg
    168.00€
    500mg
    205.00€
    1g
    531.00€
  • S-Methyl-N-cyano-N'-[2-[(5-methyl-1H-imidazol-4-yl)methylthio]ethyl]isothiourea

    CAS:

    Methylisothiourea is a label that can be used to identify cells in vivo. It is a fluorescent molecule that is activated by the presence of cytokines, such as IL-1β and TNF-α. Methylisothiourea has been used to evaluate corneal epithelial cells for their response to injury. The effect of Methylisothiourea on the tissue was assessed by histology and evaluated by the presence of cytokine concordance with the fluorescence intensity. Reconstitution experiments were conducted in vitro using human tissues. It was found that Methylisothiourea was not toxic at concentrations up to 500 μM and that it did not interfere with DNA synthesis or cell division at concentrations up to 10 mM.

    Formula:C10H15N5S2
    Purity:Min. 95%
    Color and Shape:White Powder
    Molecular weight:269.39 g/mol

    Ref: 3D-IM58264

    250g
    348.00€
    500g
    477.00€
    1kg
    710.00€
  • Decitabine impurity 11

    CAS:
    Decitabine is a drug product that is used as an anti-cancer drug. It is a synthetic, natural, and research and development (R&D) metabolite with the CAS No. 909402-26-2. Decitabine has shown anticancer activity in vitro and in vivo against leukemia cells. This compound is an impurity of the API decitabine that is manufactured by a chemical synthesis process. The analytical impurities are 11 compounds that have been identified from the HPLC standard of this API. The metabolites of these compounds are also included in this standard. High purity decitabine should be obtained for pharmacopoeia studies and niche applications such as HPLC standards, pharmaceuticals, or research purposes.
    Formula:C9H13N3O5
    Purity:Min. 95%
    Molecular weight:243.22 g/mol

    Ref: 3D-ID74837

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  • Olsalazine sodium impurity D

    CAS:

    Olsalazine sodium impurity D is a natural substance that is present as an impurity in the drug Olsalazine sodium. It is used as an analytical standard for Olsalazine sodium and its metabolites, which are involved in drug development. The purity of this substance can be customized by our research and development team. This product has CAS number 93964-55-7 and is available at a reasonable price.

    Formula:C14H9ClN2O5
    Purity:Min. 95%
    Color and Shape:Powder
    Molecular weight:320.68 g/mol

    Ref: 3D-IO63797

    50mg
    135.00€
    100mg
    197.00€
    250mg
    336.00€
    500mg
    472.00€