APIs for research and impurities
Subcategories of "APIs for research and impurities"
- Aminoacids and derivatives(12,335 products)
- Anthraquinones and derivatives(405 products)
- Benzimidazole and Imidazole Derivatives(10,451 products)
- Benzodiazepine Derivatives(334 products)
- Carbohydrates and glycoconjugates(5,048 products)
- Esters and Derivatives(42,251 products)
- Fatty Acids and Lypidic Derivatives(32,417 products)
- Flavonoids and Polyphenols(17,084 products)
- Free Radicals and Oxidant/Reducing Agents(213 products)
- Ketones and derivatives(2,402 products)
- Natural and semi-synthetic antibiotics(6,387 products)
- Nitriles and Cyano Derivatives(3,068 products)
- Nitrosamines and Derivatives(55 products)
- Nucleosides and Nucleotides(3,484 products)
- Organic Phosphates and Phosphonates(1,201 products)
- Organic Sulphonates and Sulphates(10,435 products)
- Organometallics(4,421 products)
- Others(6,307 products)
- Peptides and Proteins(3,148 products)
- Polymers and Derivatives(100 products)
- Purines and Pyrimidine Derivatives(8,948 products)
- Quinazoline and Quinoline Derivatives(66,044 products)
- Quinones and Derivatives(24,363 products)
- Salts and Derivatives of Active Pharmaceutical Ingredients (API)(80,490 products)
- Steroids and Derivatives(4,958 products)
- Sulfonamides and Derivatives(2,600 products)
- Terpenoids and Derivatives(3,849 products)
- Thiazolidinediones and Thiopyrans(2,754 products)
- β-Adrenergic Compounds(231 products)
Found 57768 products of "APIs for research and impurities"
Mch-1 antagonist 1
CAS:Mch-1 antagonist 1 is a drug product that is custom synthesized and is available in high purity. This compound is analytical, and it has been shown to be metabolized in vivo. Metabolism studies have been performed using this compound for the purposes of drug development. CAS No. 1039825-68-7 is the unique identification number for this compound, and it appears on the U.S. Drug Enforcement Administration's list of controlled substances as a natural product. It can be found in the pharmacopoeia as both a synthetic and natural product, with its synthetic form being an impurity standard for HPLC analysis. Mch-1 antagonist 1 has also been studied for its potential use in niche areas such as research and development of drugs or as an analytical standard for HPLC analysis.
Formula:C25H26N4O2Purity:Min. 95%Molecular weight:414.5 g/molRef: 3D-PRB82568
Discontinued productLeuprolide acetate ep impurity F
CAS:Leuprolide acetate ep impurity F is a drug product that is an impurity standard for the leuprolide acetate API. It is used in analytical and clinical studies to identify the presence of leuprolide acetate impurities, as well as to determine the metabolism of leuprolide acetate. Leuprolide acetate ep impurity F has been shown to be a natural metabolite of leuprolide acetate and have a niche application in pharmacopoeia.
Formula:C61H85F3N16O14Purity:Min. 95%Molecular weight:1,323.4 g/molTianeptine ethyl ester
CAS:Tianeptine is a drug product that belongs to the group of antidepressants. It is metabolized by cytochrome P450 enzymes in the liver and excreted in urine. Tianeptine ethyl ester is used as an analytical reference standard for the tianeptine content of HPLC samples. The CAS number for tianeptine ethyl ester is 66981-77-9.
Formula:C23H29ClN2O4SPurity:Min. 95%Molecular weight:465.00 g/molRef: 3D-RCA98177
Discontinued product2-Methoxy-5-sulfamoylbenzoic acid
CAS:2-Methoxy-5-sulfamoylbenzoic acid (2MSBA) is a reactive compound that reacts with the proton of vancomycin to form a dianion. This reaction is reversible and can be catalyzed by chloride ions. 2MSBA has been shown to be active against Staphylococcus, including MRSA strains, but not against Enterococci or Clostridium difficile. 2MSBA can be used in combination with cefepime or benzoate as an antibacterial agent. It also has antifungal properties, which may be due to its ability to inhibit the synthesis of ergosterol, an important component of fungal cell membranes.
2-Methoxy-5-sulfamoylbenzoic acid is related to fluconazole in that it contains a benzoate moiety and an amide group. These structural features confer antibacterial and antifFormula:C8H9NO5SPurity:Min. 95%Molecular weight:231.23 g/molRef: 3D-IM145487
Discontinued productN-[2-[(8R)-1,6,7,8-Tetrahydro-6-oxo-2H-indeno[5,4-b]furan-8-yl]ethyl]propanamide
CAS:N-[2-[(8R)-1,6,7,8-Tetrahydro-6-oxo-2H-indeno[5,4-b]furan-8-yl]ethyl]propanamide is a synthetic compound that has not been identified in nature. It is used for analytical purposes and as an impurity standard in the synthesis of other compounds. N-[2-[(8R)-1,6,7,8-Tetrahydro-6-oxo-2H-indeno[5,4-b]furan-8-yl]ethyl]propanamide is the parent drug product of CAS No. 896736–22–4. The impurities found in this product are N-[2-(3′-(3″S″)-3′′S″′) (3″R″) -1H -indenyl](methyl)amine hydrochloride and N-[
Formula:C16H19NO3Purity:Min. 95%Molecular weight:273.33 g/molRef: 3D-WKB73622
Discontinued product4-Desmethyl 5-methyl vortioxetine hydrochloride
CAS:Please enquire for more information about 4-Desmethyl 5-methyl vortioxetine hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C18H23ClN2SPurity:Min. 95%Molecular weight:334.9 g/molRef: 3D-MKD72214
Discontinued product(-)-Bornyl ferulate
CAS:Controlled Product(-)-Bornyl ferulate is a natural compound, specifically a type of ferulic acid ester, which is a secondary metabolite found in certain plants. Its source is primarily the essential oils and resins of various coniferous species, where it contributes to the plant's defense mechanisms. The mode of action of (-)-Bornyl ferulate involves its ability to scavenge free radicals, thus exhibiting antioxidant activity. It also modulates inflammatory pathways, suggesting possible anti-inflammatory effects.
Formula:C20H26O4Purity:Min. 95%Molecular weight:330.42 g/molRef: 3D-FCA51107
Discontinued productN-Trityl candesartan ethyl ester
CAS:N-Trityl candesartan ethyl ester is a drug product that has been custom synthesized for research and development purposes. It is an impurity standard for the synthesis of metoprolol. The compound was synthesized as a synthetic intermediate to be used in an analytical study, and is not found in nature. N-Trityl candesartan ethyl ester is chemically similar to Metoprolol and can be used as an impurity standard for HPLC analysis of Metoprolol or other drugs containing Metoprolol.
Formula:C45H38N6O3Purity:Min. 95%Molecular weight:710.80 g/molRef: 3D-XWC98581
Discontinued productTc 1698 dihydrochloride
CAS:Tc 1698 dihydrochloride is a tumor-promoting agent that inhibits the growth of tumor tissues. It has been shown to inhibit the proliferation of human retinal pigment epithelial cells in vitro, which may be due to its ability to induce flavanones. Tc 1698 dihydrochloride can also act as an inducer for the production and release of cytokines, such as IL-6, IL-8 and monocyte chemoattractant protein 1. This agent has been shown to promote angiogenesis and stimulate collagen synthesis in skin fibroblasts.
Formula:C13H20Cl2N2Purity:Min. 95%Molecular weight:275.21 g/molRef: 3D-MGB58706
Discontinued product1-[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]thio]-1H-benzi midazole
CAS:1-[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]thio]-1H-benzi midazole is a high purity analytical standard that is used to calibrate HPLC. It is found as an impurity in the drug product and as a metabolite. 1-[(3-Methyl-4-(2,2,2 -trifluoroethoxy) - 2 - pyridinyl) methyl] - 2 - [[[3 - methyl (4 ( 2 , 2 , 2 - trifluoroethoxy) - 2 pyridinyl) methyl] thio] - 1 H benzimidazole is the IUPAC name for this compound. This chemical has been synthesized
Formula:C25H22F6N4O2SPurity:Min. 95%Molecular weight:556.52 g/molRef: 3D-IM25690
Discontinued productTrazodone Hydrochloride BP Impurity A
CAS:Trazodone Hydrochloride BP Impurity A is an unproven impurity of Trazodone. It inhibits the uptake of serotonin by 5-HT receptors, which may be important in the treatment of depression. This compound also inhibits platelet aggregation and has been found to inhibit the activity of tricyclic compounds, such as piperazine and propionic acid.Formula:C19H22CIN5O2Purity:Min. 95%Molecular weight:491.33 g/molRef: 3D-IT171024
Discontinued product1-[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-b enzimidazole
CAS:1-[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-b enzimidazole is an impurity of a drug product. It is a metabolite that has been shown to be present in human plasma and urine. This compound is synthetically produced and is not found in nature. It has been shown to have niche applications in both analytical chemistry and pharmacopoeia.
Formula:C25H22F6N4O3SPurity:Min. 95%Molecular weight:572.52 g/molRef: 3D-IM25689
Discontinued productLoperamide N-oxide
CAS:Loperamide N-oxide is an analog of loperamide, which is commonly used as an anti-diarrheal medication. It has been shown to have potential anti-cancer properties by inducing apoptosis in cancer cells. Loperamide N-oxide has also been detected in urine samples from Chinese individuals, indicating its potential use as a biomarker for cancer diagnosis. This compound has been found to inhibit trypsin-like kinases, which are enzymes involved in cell division and proliferation. In addition, loperamide N-oxide has been shown to inhibit the growth of tumor cells and may have potential as a therapeutic agent for cancer treatment. However, it should be noted that rifampicin and other inhibitors can reduce the effectiveness of loperamide N-oxide against cancer cells. Further research is needed to fully understand the potential benefits and limitations of this compound.
Formula:C29H33ClN2O3Purity:Min. 95%Molecular weight:493 g/molRef: 3D-SIA47103
Discontinued productPhenothiazine S,S-dioxide
CAS:Phenothiazine S,S-dioxide is a fluorescent anion that can be used as a buffer. It has an absorption maximum at 514 nm in the visible region and a fluorescence emission maximum at 592 nm. Phenothiazine S,S-doxide blocks the emission of light from phosphor by absorbing the light and reemitting it at a longer wavelength. The luminescence intensity increases with increasing concentration of phenothiazine S,S-dioxide. This compound has been used to develop devices that detect anions in drinking water such as chloride ion. Phenothiazines are also known to have anti-inflammatory effects due to their ability to inhibit prostaglandin synthesis.
Formula:C12H9NO2SPurity:Min. 95%Molecular weight:231.27 g/molRef: 3D-BAA20966
Discontinued product4,6-Dimethoxy-β-methyl-3-phenoxy ambrisentan
CAS:Controlled Product4,6-Dimethoxy-β-methyl-3-phenoxy ambrisentan is a synthetic drug with a high purity and pharmacopoeia. It belongs to the group of drugs called prostanoids, which are lipid molecules that act as hormones. 4,6-Dimethoxy-β-methyl-3-phenoxy ambrisentan is used in research and development for the treatment of pulmonary arterial hypertension. It is an impurity standard for HPLC analysis. This compound can be custom synthesized for drug product research and development. Metabolism studies have been conducted on this compound. The metabolites have been identified as 4,6-dimethoxy-(E)-2-[(E)-2-(4'-methylbenzylidene)ethenyl]-3-[(Z)-1-(4'-methylbenzylidene)ethenyl]ambrinol (M1), 4,6-dimethoxy-(E)-Formula:C22H22N2O6Purity:Min. 95%Molecular weight:410.4 g/molRef: 3D-JGA30803
Discontinued product(1R)-Perindopril t-butylamine
CAS:Enantiomer of Perindopril t-Butylamine
Formula:C23H43N3O5Purity:Min. 95%Molecular weight:441.6 g/molRef: 3D-FP64047
Discontinued productDesacetyl bisacodyl β-D-glucuronide
CAS:Desacetyl bisacodyl β-D-glucuronide is a drug product that is used as an impurity standard in analytical chemistry. It is a synthetic chemical that has been custom synthesized for research and development of drugs. The CAS number for this compound is 31050-47-2 and the molecular weight is 526.25 g/mol. This compound has not been approved by the FDA, but it has been shown to be pharmacologically active in animal studies. Desacetyl bisacodyl β-D-glucuronide can be ordered from our website at www.customsynthesislab.com
Formula:C24H23NO8Purity:Min. 95%Molecular weight:453.4 g/molRef: 3D-GBA05047
Discontinued productTolterodine S-enantiomer
CAS:Tolterodine S-enantiomer is a drug product that belongs to the class of prodrugs. It is metabolized in vivo to the active form, tolterodine. Tolterodine S-enantiomer has been shown to have a natural origin and can be found in plants and animals. Metabolism studies of this compound have been conducted in human liver microsomes, with the major metabolite being tolterodine. Tolterodine S-enantiomer also has pharmacopoeia standards, including an analytical standard and an impurity standard, as well as an HPLC standard for research and development purposes.
Formula:C22H31NO·C4H6O6Purity:Min. 95%Molecular weight:475.57 g/molRef: 3D-YJB55103
Discontinued productTorasemide EP Impurity C
CAS:Torasemide EP Impurity C is a drug product that is used as an analytical standard in the metabolism studies of torasemide. Torasemide EP Impurity C belongs to the group of metabolites, and it has been shown to have pharmacopoeia standards. Torasemide EP Impurity C can be found in natural products, but also synthesized in laboratories.
Formula:C15H18N4O3SPurity:Min. 95%Molecular weight:334.39 g/molAjoene
CAS:Ajoene is a natural compound that has been shown to have antimicrobial properties, as well as an ability to inhibit the growth of tumor cells. Ajoene is also a potent inhibitor of dextran sulfate proteoglycan synthesis in vitro and has been shown to produce a hypoglycemic effect in vivo. Ajoene has been shown to be active against Gram-positive bacteria and fungi and may have potential applications for the treatment of infectious diseases. Further research is needed to determine whether ajoene may be used as an antioxidant or neuroprotective agent.
Formula:C9H14OS3Purity:Min. 95%Molecular weight:234.4 g/molRef: 3D-SDA28499
Discontinued productAlpha-amino-4-octylbenzenebutanoic acid
CAS:Alpha-amino-4-octylbenzenebutanoic acid is an impurity standard for pharmacopoeia and drug development. It is a synthetic compound that has been shown to be a metabolite of the muscle relaxant succinylcholine. Alpha-amino-4-octylbenzenebutanoic acid is a high purity, custom synthesis material and can be used as a reference or calibration standard in analytical techniques such as HPLC.
Formula:C18H29NO2Purity:Min. 95%Molecular weight:291.40 g/molRef: 3D-WYA82019
Discontinued productN-(4-Amino-6,7-dimethoxyquinazol-2-yl)-N-methylpropylenediamine hydrochloride
CAS:N-(4-Amino-6,7-dimethoxyquinazol-2-yl)-N-methylpropylenediamine hydrochloride is an impurity that can be found in some commercially available drugs. It is a metabolite of the drug N-(4-amino-6,7-dimethoxyquinazol-2-yl)propylenediamine and is used as a reference standard for HPLC analysis. This compound has been shown to have antiplatelet activities.
Formula:C14H22ClN5O2Purity:Min. 95%Molecular weight:327.81 g/molRef: 3D-FA17652
Discontinued productXanthoxin
CAS:Xanthoxin is a medicinal compound with potent anticancer properties. It has been shown to induce apoptosis, or programmed cell death, in cancer cells. Xanthoxin has been tested in various cancer cell lines, including Chinese and human cells, and has demonstrated strong inhibitory effects on the tumor cycle. This compound works by inhibiting kinases and other proteins involved in cancer cell growth and proliferation. Xanthoxin is also known to be an inhibitor of certain urinary proteins that are associated with cancer progression. Overall, Xanthoxin shows great potential as a natural product for the development of novel anticancer therapies.
Formula:C15H22O3Purity:Min. 95%Molecular weight:250.33 g/molRef: 3D-IAA06607
Discontinued productRisperidone carboxylate impurity
CAS:Risperidone carboxylate impurity is an analytical reference standard of risperidone that is used in the research and development, drug development, and production of drugs. It can be used as an impurity standard for the manufacture of pharmaceuticals. Risperidone carboxylate impurity has a molecular weight of 514.83 g/mol and a melting point of 200-202°C. Its CAS number is 1346603-86-8. Metabolites are also known to form from risperidone carboxylate impurity during metabolism.
Formula:C24H27FN4O4Purity:Min. 95%Molecular weight:454.50 g/molRef: 3D-WDC60386
Discontinued productBendamustine isopropyl ester
CAS:Bendamustine isopropyl ester is a synthetic, high purity drug product. It is an impurity standard for the manufacture of Bendamustine hydrochloride, a drug product that is used in cancer chemotherapy. Bendamustine isopropyl ester has been shown to inhibit the metabolism of bendamustine hydrochloride and may be useful as a pharmacokinetic marker in clinical trials. Bendamustine isopropyl ester metabolizes into bendamustine hydroxypyridinium salt, which has been shown to have anti-inflammatory properties.
Formula:C19H27Cl2N3O2Purity:Min. 95%Molecular weight:400.30 g/molRef: 3D-NCC02025
Discontinued product17-o-(Acetyl-d3)-6-methylprednisolone
CAS:Controlled Product17-o-(Acetyl-d3)-6-methylprednisolone is a drug product that belongs to the group of corticosteroids. It is used for the treatment of inflammatory conditions and autoimmune diseases. This API is used as an impurity standard in analytical methods such as HPLC, and it can be synthesized from natural sources or synthetically. 17-o-(Acetyl-d3)-6-methylprednisolone can also be used in R&D for the development of drugs targeting niche markets, such as those with high purity requirements.
Formula:C24H29D3O6Purity:Min. 95%Molecular weight:419.53 g/molRef: 3D-LDA40194
Discontinued productSalbutamol Impurity D
CAS:Salbutamol Impurity D is a chiral, metal chelator impurity of the drug substance Salbutamol. It is a prodrug that is hydrolyzed to its active form, salbutamol sulfate, in vivo. Salbutamol Impurity D binds to chloride ions and has been shown to be an interferent for many analytical methods. The reversed-phase chromatography retention time for Salbutamol Impurity D is about 10 minutes shorter than for Salbutamol sulfate.
Formula:C13H19NO3Purity:Min. 95%Molecular weight:237.29 g/molMesulergine hydrochloride
CAS:Mesulergine hydrochloride is a drug that inhibits the dopamine and serotonin receptors. It has been shown to have an effect on rats' serum prolactin levels, food composition, and protein transport in the striatum. Mesulergine hydrochloride can also decrease 5-HT7 receptor binding and increase dopamine release from nerve terminals in the rat brain. This drug has synergistic effects with other drugs when used in combination, such as gamma-aminobutyric acid (GABA) or benzodiazepines.
Symptoms of mesulergine hydrochloride include psychotic disorders, anxiety, depression, hallucinations, sleep problems, and suicidal thoughts. These symptoms may be due to mesulergine's effect on 5-HT2C receptors.Formula:C18H27ClN4O2SPurity:Min. 95%Molecular weight:399 g/molRef: 3D-XCA78612
Discontinued productBinospirone hydrochloride
CAS:Binospirone hydrochloride is a drug product that is used in the treatment of depression. It belongs to the class of antidepressants and has been shown to be effective against major depressive disorder (MDD). Binospirone hydrochloride is metabolized by cytochrome P450 enzymes into two metabolites: 3-hydroxybinospirone and 2,3-dihydroxybinospirone. The natural form of binospirone hydrochloride is synthesized from tyrosine and phenylalanine. It is also found as an impurity in other pharmaceuticals, such as clomipramine, amitriptyline, and fluoxetine. It has been shown that this compound binds to the serotonin transporter (SERT) at high affinity. This binding inhibits the reuptake of serotonin from synapses, leading to increased extracellular concentrations of serotonin.
Formula:C20H27ClN2O4Purity:Min. 95%Molecular weight:394.9 g/molRef: 3D-CEA90860
Discontinued productGyromitrin
CAS:Gyromitrin is a potent inhibitor of tumor growth and apoptosis in human cancer cells. It is an analog of tylosin, a macrolide antibiotic used in veterinary medicine. Gyromitrin has been shown to inhibit the activity of kinases involved in cell proliferation and survival, leading to decreased cell growth and increased apoptosis. In Chinese hamster ovary cells, gyromitrin has been demonstrated to be a potent inhibitor of protein synthesis. This compound has also been found in urine samples from humans who have ingested mushrooms containing gyromitrin. Menthol has been found to be an effective inhibitor of gyromitrin-induced DNA damage and may have potential as a chemopreventive agent against cancer.
Formula:C4H8N2OPurity:Min. 95%Molecular weight:100.12 g/molRef: 3D-RAA56802
Discontinued productDuloxetine phenyl carbamate
CAS:Duloxetine is a drug product that belongs to the class of drugs known as selective serotonin and norepinephrine reuptake inhibitors. Duloxetine is a metabolite of duloxetine phenyl carbamate, which is an impurity standard for HPLC analysis. Duloxetine has been shown to inhibit the metabolism of serotonin and norepinephrine in the brain, leading to increased amounts of these neurotransmitters. This medication has been studied in niche populations such as those with depression and diabetic neuropathy. Duloxetine also has high purity standards, meeting the requirements of pharmacopoeia.
Formula:C25H23NO3SPurity:Min. 95%Molecular weight:417.50 g/molRef: 3D-XMB68609
Discontinued productSr 33805 oxalate
CAS:Sr 33805 oxalate is a potent inhibitor of cell proliferation that is used in the treatment of cancer. It has been shown to inhibit tumor growth and invasion in vivo by binding to the beta-subunit of voltage-gated potassium channels, which leads to decreased cellular proliferation and autophagy. Sr 33805 oxalate also inhibits cancer cells by inhibiting mitosis and inducing apoptosis. This agent has cytotoxic effects on brain cells, with an IC50 value of 0.1 μM in vitro against rat cerebellar neurons. In addition, it has been shown to be highly selective for cancer cells over normal brain tissue in vivo, with a potency that is 10 times greater than gatifloxacin.
Formula:C34H42N2O9SPurity:Min. 95%Molecular weight:654.8 g/molRef: 3D-WEA34633
Discontinued product11-Oxo-betamethasone-17-carboxylic acid
CAS:Controlled ProductPlease enquire for more information about 11-Oxo-betamethasone-17-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C21H25FO5Purity:Min. 95%Molecular weight:376.4 g/molRef: 3D-EDA57810
Discontinued productDi(2-(4-(dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl))-2-propoxyethyl propionate
CAS:Di(2-(4-(dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl))-2-propoxyethyl propionate is a synthetic compound that is used in research and development for the analytical standard of dibenzothiazepine 11 (DBT). It has been shown to be an impurity in pharmaceutical products and as a metabolite. Di(2-(4-(dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl))-2-propoxyethyl propionate is also used as a pharmacopoeia reference material in the manufacture of analytical standards of DBZ. CAS No. 1798840-31-9
Formula:C40H42N6O3S2Purity:Min. 95%Molecular weight:718.90 g/molRef: 3D-YWC84031
Discontinued product1-Hydroxy carvedilol
CAS:1-Hydroxycarvedilol is a drug product that is used as a standard in HPLC. It is a natural metabolite of carvedilol and has been found to be involved in the metabolism of carvedilol. The purity of 1-hydroxycarvedilol is >98%. This product is also an impurity standard for analytical purposes and an API impurity. It can also be used in metabolism studies and has CAS No. 146574-41-6.
Formula:C24H26N2O5Purity:Min. 95%Molecular weight:422.50 g/molRef: 3D-WFA57441
Discontinued productcis-Tadalafil
CAS:Cis-Tadalafil is a potent inhibitor of phosphodiesterase 5, which is used to treat erectile dysfunction (ED) and primary pulmonary hypertension (PPH). It works by increasing blood flow to the penis, allowing men with ED to achieve and maintain an erection. Cis-Tadalafil is also used to treat symptoms of prostatic hyperplasia (enlarged prostate) in men. This drug has been shown to be effective in treating PPH by reducing pulmonary arterial pressure and improving exercise capacity. Cis-Tadalafil belongs to the carboline class of drugs and is a phosphodiesterase 5 inhibitor that selectively inhibits cGMP-specific phosphodiesterase type 5 (PDE5). This drug has been shown to be highly effective in treating both ED and PPH with minimal side effects.
Formula:C22H19N3O4Purity:Min. 95%Color and Shape:White/Off-White SolidMolecular weight:389.4 g/molAcarbose Impurity E
CAS:Acarbose Impurity E is an impurity found in acarbose. It is a natural, API impurity and is a synthetic impurity standard. Acarbose Impurity E has been used in drug development research and development, as well as in the HPLC analysis of acarbose to generate a pharmacopoeia-grade purity standard.
Purity:Min. 95%N-Desacetyl thiocolchicoside
CAS:N-Desacetyl thiocolchicoside is a white crystalline powder that is soluble in water, methanol and acetone. It has a molecular weight of 320.2 and an empirical formula of C6H14O5. N-Desacetyl thiocolchicoside is used as an analytical standard for HPLC analysis, as a Research and Development (R&D) material for drug development, and as an impurity standard for the manufacture of pharmaceutical products. This compound has been shown to be a metabolite of thiocolchicoside and structurally similar to the drug product chitinase.
Formula:C25H31NO9SPurity:Min. 95%Molecular weight:521.58 g/molRef: 3D-CHA99181
Discontinued productOxacyclohexane open ring tacrolimus
CAS:Please enquire for more information about Oxacyclohexane open ring tacrolimus including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C44H71NO13Purity:Min. 95%Molecular weight:822.04 g/molEmpagliflozin S-furanose
CAS:Empagliflozin S-furanose is a Custom synthesis drug product. It is an analytical standard with CAS No. 1620758-32-8, and it is used in research and development of new drugs. Empagliflozin S-furanose has been found to be a metabolite of empagliflozin, a drug that is used to treat type 2 diabetes mellitus. It is also used as an impurity standard for HPLC analysis of empagliflozin because it does not have any biological activity.
Formula:C23H27ClO7Purity:Min. 95%Color and Shape:PowderMolecular weight:450.91 g/molRef: 3D-IE181148
Discontinued productCiprofloxacin ep impurity C
CAS:Ciprofloxacin ep impurity C is a synthetic compound. It is used as a research and development standard in the synthesis of ciprofloxacin. The purity of this compound is high, and it has been tested for metabolism studies. This impurity can be detected by HPLC using an analytical method with a natural reference substance. This impurity has not been evaluated for pharmacopoeia or CAS number.
Formula:C15H16FN3O3Purity:Min. 95%Molecular weight:305.30 g/molRef: 3D-DEA22212
Discontinued productN-Hydroxymethyl Sumatriptan
CAS:N-Hydroxymethyl Sumatriptan is an analytical standard and a research and development impurity. It is also used as an API impurity in drug product manufacturing. N-Hydroxymethyl Sumatriptan can be synthesized by reacting the parent drug with hydroxyl radicals, which is a process that yields no side products. N-Hydroxymethyl Sumatriptan can be found in the following pharmacopoeia: United States Pharmacopoeia (USP) 11>, European Pharmacopoeia (EP), Japanese Pharmacopoeia (JP)13>, British Pharmacopoeia (BP), and Chinese Pharmacopiae (CPC).
Formula:C15H23N3O3SPurity:Min. 95%Molecular weight:325.43 g/mol3-Dimethylaminopropyl-2-benzylaminobenzoate hydrochloride
CAS:3-Dimethylaminopropyl-2-benzylaminobenzoate hydrochloride is a versatile compound with various characteristics and applications. It has been found to have diverse effects on different biological processes. This compound has shown potential as an antimuscarinic agent, which means it can block the action of acetylcholine at muscarinic receptors in the body.
Formula:C19H25ClN2O2Purity:Min. 95%Molecular weight:348.9 g/molRef: 3D-WMD18565
Discontinued product(3S,4R)-Tofacitinib
CAS:(3S,4R)-Tofacitinib is a rhombic and paramagnetic compound with a Curie point of approximately 10.6°C. It is soluble in nonpolar solvents such as benzene and toluene. (3S,4R)-Tofacitinib has been shown to have magnetic properties that are dependent on the temperature and the frequency of the applied magnetic field. The paramagnetic resonance spectra were observed at 18°C and 32°C, while the paramagnetic resonance spectrum was observed at -2°C. The octahedral interactions are likely due to the presence of six different types of iron ions in the crystal structure.
Formula:C16H20N6OPurity:Min. 95%Molecular weight:312.37 g/molLinagliptin impurity G
CAS:Linagliptin impurity G is an impurity in the drug product Linagliptin. It is a natural substance and its CAS number is 668270-11-9. Impurity G can be synthesized from L-phenylalanine and cyclohexane carboxaldehyde in a two step process. The first step involves the reaction of L-phenylalanine with cyclohexane carboxaldehyde to yield methylcyclohexanecarboxylate, which then undergoes hydrolysis to give phenylcyclohexanol. In the second step, phenylcyclohexanol reacts with hydrochloric acid to produce phenylcyclohexanone, which is then oxidized with hydrogen peroxide to yield impurity G. Impurity G can also be found in the pharmacopoeia as a high purity HPLC standard for linagliptin.
Formula:C25H28N8O2Purity:Min. 95%Color and Shape:PowderMolecular weight:472.54 g/molDesfluoro ezetimibe
CAS:Desfluoro ezetimibe is a synthetic cholesterol-lowering drug that inhibits intestinal cholesterol absorption. It is chemically synthesized, and the process includes the introduction of fluorine at the 3-position of the C-ring. Desfluoro ezetimibe is not metabolized in humans, but it may be subject to oxidative degradation. The product is also subject to oxidation by light and air, which may result in formation of impurities. The drug substance has been validated as well as its isomers and efficiencies in mass spectrometry detection.
Formula:C24H22FNO3Purity:Min. 95%Color and Shape:White To Off-White SolidMolecular weight:391.43 g/mol2-(2-Amino-5-bromobenzoyl)pyridine
CAS:2-(2-Amino-5-bromobenzoyl)pyridine (2ABBP) is a chemical compound with the molecular formula C10H7BrN3. It is a glucuronide conjugate of 2-amino-5-bromobenzoic acid and has been used as an immunological reagent in the form of a monoclonal antibody. 2ABBP binds to dryopteris, which is a plant species that contains polyphenols called pteridines. 2ABBP has been shown to have anti-inflammatory properties in rat liver microsomes and cell culture experiments. The mechanism of action may involve inhibition of cyclooxygenase enzymes, which are involved in prostaglandin synthesis. 2ABBP also binds to human serum albumin and chaperones, proteins that bind other proteins or small molecules. The biological activity of 2ABBP may be due to its ability to form coval
Formula:C12H9BrN2OPurity:Min. 95%Molecular weight:277.12 g/molPiperacilloic acid
CAS:Piperacilloic acid is a synthetic compound that exhibits antibacterial activity. It has been shown to be effective against human pathogens, including urothelial carcinoma and human serum. Piperacilloic acid binds to the amino acids lysine and arginine in bacterial proteins and inhibits protein synthesis by inhibiting the function of enzymes that require these amino acids for their activity. The potency of piperacillin is low, but it is activated by hydrolysis in the acidic environment of the stomach or intestinal tract. Piperacilloic acid also has potential as a contraceptive agent because it may inhibit transcriptional regulation of genes that are involved in sperm production.
Formula:C23H29N5O8SPurity:(Elemental Analysis) Min. 90 Area-%Color and Shape:PowderMolecular weight:535.57 g/molSimvastatin acid
CAS:Simvastatin acid is the active form of simvastatin, a drug used to lower blood cholesterol levels. Simvastatin acid inhibits HMG-CoA reductase, the enzyme that converts HMG-CoA to mevalonate. This conversion is a rate-limiting step in the synthesis of cholesterol and other lipids. Simvastatin acid binds to polymerase chain and drug transporter proteins, which leads to cell lysis. The concentration–time curve for simvastatin acid is linear and the half-life is approximately 12 hours. When simvastatin acid is administered with drugs that are potent inducers of CYP3A4 or UGT1A1 enzymes, there may be an increased risk for drug interactions. Simvastatin acid has shown no significant human pharmacokinetic interactions with food or grapefruit juice at doses up to 200 mg/day. There are limited data on the pharmacokinetics of simvastatin
Formula:C25H40O6Purity:Min. 95%Color and Shape:White PowderMolecular weight:436.58 g/molRef: 3D-IS63828
Discontinued product(S)-Rabeprazole sodium
CAS:(S)-Rabeprazole sodium is an anticancer drug that acts as a kinase inhibitor. It is an analog of Rabeprazole and has been shown to inhibit the growth of cancer cells in vitro and in vivo. (S)-Rabeprazole sodium inhibits the activity of kinases, which are enzymes that play a key role in cell signaling pathways. This inhibition leads to apoptosis, or programmed cell death, in cancer cells. (S)-Rabeprazole sodium has been tested against various types of cancer, including Chinese hamster ovary cells and tumor xenografts in mice. It has also been shown to inhibit elastin degradation, which is important for preventing metastasis of cancer cells. (S)-Rabeprazole sodium may be a promising candidate for the development of new anticancer drugs that target specific kinases and proteins involved in cancer cell growth and survival.
Formula:C18H21N3O3S•NaPurity:Min. 95%Molecular weight:382.43 g/molRef: 3D-IR183125
Discontinued productN-Nitroso dorzolamide
N-Nitroso dorzolamide is a chemical compound used as an intermediate in the synthesis of dorzolamide, a carbonic anhydrase inhibitor used in the treatment of glaucoma and ocular hypertension.
Formula:C10H15N3O5S3Purity:Min. 95%Color and Shape:PowderMolecular weight:353.44 g/molSacubitril Impurity 2
CAS:Sacubitril Impurity 2 is a drug product that is an analytical impurity in Sacubitril. This impurity can be found in Sacubitril as a result of natural processes or as an API impurity during the synthesis process. Sacubitril Impurity 2 has been shown to have activity in Metabolism studies, Natural, and Custom synthesis. It has been shown to be a Synthetic impurity standard and HPLC standard. Sacubitril Impurity 2 is used for research and development purposes for the drug development industry, specifically for the niche market. It is also used as an analytical standard for pharmacopoeia methods.
Formula:C24H27NO4Purity:Min. 95%Molecular weight:393.48 g/molDicyclopropylamine hydrochloride
CAS:Dicyclopropylamine hydrochloride is a tyrosine kinase inhibitor that blocks the activity of jak2. It is an innovative molecule with the potential to be used in cancer treatment. Dicyclopropylamine hydrochloride has been shown to inhibit activation of tyrosine kinases, which are involved in cell signaling and proliferation. Dicyclopropylamine hydrochloride also has anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis. This drug is not expected to have any toxicity or side effects because it can be easily metabolized by the liver.br>br> Dicyclopropylamine hydrochloride is a white solid with a melting point of 175°C. It has no detectable odor, and it is soluble in water and ethanol. The impurities found in this compound include myristic acid and amines, which can cause inflammatory diseases.br>br> D
Formula:C6H11N•HClPurity:Min. 95%Color and Shape:PowderMolecular weight:133.62 g/molRef: 3D-FD141573
Discontinued productTofacitinib dihydro impurity
CAS:Tofacitinib dihydro impurity is a research and development impurity standard for the synthesis of Tofacitinib. It is a custom synthesis with high purity, pharmacopoeia grade, and synthetic. This product is also used in drug development for metabolism studies and analytical applications.
Formula:C16H22N6OPurity:Min. 95%Molecular weight:314.39 g/molIvermectin impurity I
CAS:Ivermectin impurity I is an analytical standard that is used for pharmacopoeia and custom synthesis. It is a natural metabolite of the drug Ivermectin, which has been shown to have anti-inflammatory properties in mice. Ivermectin impurity I binds to nicotinic acetylcholine receptors, leading to muscle paralysis and death. This compound is found in high purity for research and development purposes.
Formula:C48H74O14Purity:Min. 95%Color and Shape:PowderMolecular weight:875.09 g/molRef: 3D-II167729
Discontinued productN-Benzyl albuterol
CAS:N-Benzyl albuterol is a drug product that is custom synthesized to be of high purity with an analytical standard. It is used in research and development, pharmaceutical development, and as a pharmacopoeia or analytical standard. N-Benzyl albuterol has been found to be a metabolite of the drug product Albuterol Sulfate. It is also used in metabolism studies and natural product research. The CAS number for this compound is 24085-03-8.
Formula:C20H27NO3Purity:Min. 95%Molecular weight:329.4 g/molRocuronium Bromide EP Impurity F Bromide
CAS:Rocuronium Bromide EP Impurity F Bromide is an impurity found in Rocuronium Bromide EP. It is a natural component of the drug product, which is a synthetic drug. The metabolite of this impurity is also found in the natural product, although at much lower concentrations. This impurity has been shown to be present as an analytical impurity in the API and custom synthesis process. This impurity standard has been synthesized synthetically for use in drug development and research and development, as well as for use in HPLC standards.Formula:C34H55N2O4·BrPurity:Min. 95%Molecular weight:635.72 g/molRoflumilast Impurity A
CAS:Roflumilast impurity A is a metabolite of roflumilast. It is a drug product that is used as an analytical standard for the determination of roflumilast in HPLC analysis. Roflumilast impurity A is not natural and is synthetic. It has been shown to be a substrate for CYP1A2, CYP2C8, CYP2C9, and CYP3A4 enzymes. Studies have shown that it may be involved in the metabolism of roflumilast through hydroxylation and deamination.
Formula:C16H14Cl2N2O3Purity:Min. 95%Molecular weight:353.2 g/molPramipexole EP Impurity C
CAS:Pramipexole EP Impurity C is a synthetic impurity that is used as an impurity standard in the manufacture of Pramipexole EP. It is also used as a research and development tool for drug product, custom synthesis, CAS No. 1973461-14-1, and analytical studies. This compound has been shown to be a metabolite of Pramipexole EP and may have pharmacological properties. Pramipexole EP Impurity C has been found to inhibit the growth of certain bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA) isolates.
Formula:C20H32N6S2Purity:Min. 95%Terbinafine dihydrochloride
CAS:Terbinafine is a drug used in the treatment of onychomycosis, tinea versicolor and dandruff. It belongs to the group of medicines known as antifungals and inhibits the growth of fungi by inhibiting their ability to make proteins. Terbinafine dihydrochloride is a form of terbinafine that is more soluble in water than terbinafine hydrochloride and can be used as a lubricant. Terbinafine hydrochloride is an industrial product that is used as a disintegrant in tablets and capsules.
Formula:C36H40N2Purity:Min. 95%Molecular weight:500.7 g/molRef: 3D-JMB36523
Discontinued product(4-Chlorophenyl)diphenylmethanol
CAS:Please enquire for more information about (4-Chlorophenyl)diphenylmethanol including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C19H15ClOPurity:Min. 95%Molecular weight:294.8 g/molRef: 3D-GAA92289
Discontinued productD-6-Cyano-6-norlysergic acid methyl ester
CAS:Please enquire for more information about D-6-Cyano-6-norlysergic acid methyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page
Formula:C17H15N3O2Purity:Min. 95%Molecular weight:293.32 g/molRef: 3D-FBA33404
Discontinued productChlorthalidone impurity E
CAS:Chlorthalidone impurity E is an analytical standard for the HPLC analysis of chlorthalidone in pharmaceutical drug products and is a metabolite of chlorthalidone. Chlorthalidone impurity E is an API impurity that can be found in the synthesis of chlorthalidone, and it has been detected as a minor component in certain drug products. It is important to have an accurate specification for this compound, since it can affect the pharmacological properties of the drug product. The purity level of this compound must be at least 98% or greater to ensure that there are no contaminants present. This compound is also a metabolite of chlorthalidone and is used as a pharmacopoeia reference substance for testing equipment calibration.END>
Formula:C14H11ClN2O3SPurity:Min. 95%Molecular weight:322.77 g/molRef: 3D-IC76330
Discontinued productTriethylene glycol flufenamate
CAS:Etofenamate impurity
Formula:C20H22F3NO5Purity:Min. 95%Color and Shape:Clear LiquidMolecular weight:413.39 g/molRef: 3D-IT58094
Discontinued productGS 441524 triphosphate
CAS:Triphosphorylated form of an antiviral nucleoside analog with activity against zoonotic feline infectious peritonitis virus (FIPV) and severe acute respiratory syndrome (SARS) virus from Coronaviridae family. The compound is the biologically active form of the GS 441524 prodrug and being triphosphorylated, it competes with natural nucleoside triphosphates in cells and interferes with viral RNA synthesis. Made to order.
Formula:C12H12N5O13P3·4NaPurity:(31P-Nmr) Min. 95 Area-%Color and Shape:White PowderMolecular weight:531.20 g/molRef: 3D-FG167050
Discontinued productAtorvastatin calcium trihydrate EP Impurity G
CAS:Atorvastatin is a drug that belongs to the class of statins. It is used for the treatment of high cholesterol levels and other related diseases, such as cardiovascular disease. Atorvastatin calcium trihydrate EP Impurity G is an impurity that may be present in atorvastatin calcium trihydrate. This compound has not been found to have any pharmacological activity.
Formula:C34H37FN2O5Purity:Min. 95%Color and Shape:PowderMolecular weight:572.67 g/mol
