APIs for research and impurities

<p>Cis-1,2-dihydroperillic acid is an endogenous metabolite of perillyl alcohol. It is formed in the liver from perillyl alcohol and is excreted in the urine. Cis-1,2-dihydroperillic acid has been shown to inhibit cell growth and induce cancer in animals and humans. Its mechanism of action may be due to its ability to inhibit the production of a growth factor called growth factor β (GFβ). This hormone stimulates the proliferation of mammary carcinomas and may also be involved in carcinogenesis. Cis-1,2-dihydroperillic acid is present in plasma at low concentrations, which have been measured using a human bioassay.</p>

Cantharene is a medicinal compound that has been shown to have potent anticancer properties. It is an analog of cantharidin, a natural compound found in Chinese blister beetles. Cantharene works by inhibiting the activity of certain protein kinases, which are enzymes that play a critical role in cell cycle regulation and tumor growth. This inhibition has been shown to induce apoptosis, or programmed cell death, in cancer cells. Cantharene has been tested on human cancer cell lines and has demonstrated significant tumor-inhibitory effects. It is a promising candidate for the development of new cancer therapies and inhibitors.

<p>Please enquire for more information about Ozagrel impurity III including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Rac-Benzyl phenylephrone hydrochloride is a synthetic compound that is not found in nature. It can be used as an analytical standard or a pharmacopoeia impurity standard. Rac-Benzyl phenylephrone hydrochloride has been shown to inhibit the activity of CYP3A4, an enzyme which metabolizes many drugs. As a result, it may be useful for drug development and research and could have applications in niche markets such as natural products.</p>

<p>Please enquire for more information about Carbidopa 4-phosphate trihydrate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Fluphenazine decanoate EP impurity E is an impurity found in Fluphenazine decanoate, a drug product. Fluphenazine decanoate EP impurity E is a natural metabolite of Fluphenazine decanoate that has been synthesized for use as an analytical reference standard and as an Impurity Standard for HPLC. The CAS number for Fluphenazine decanoate EP impurity E is</p>

Dinosam is a medicinal compound that has been found to possess potent anticancer properties. It is an analog of a natural product isolated from Chinese urine and acts as an inhibitor of kinases, which are proteins involved in the regulation of cell growth and division. Dinosam has been shown to induce apoptosis (programmed cell death) in cancer cells, making it a promising candidate for cancer therapy. In addition to its anticancer effects, Dinosam has also been found to have potential as an inhibitor of other human kinases. Its unique structure and mechanism of action make it a valuable tool for the development of new kinase inhibitors with therapeutic potential.

(R)-3-Quinuclidinyl di(2-thienyl)glycolate is a Chinese-made inhibitor that targets kinases in tumor cells. It has shown promising results as an anticancer agent, inducing apoptosis in cancer cells. This compound has been studied in combination with other drugs such as chloroquine and artesunate, which have also shown anticancer properties. (R)-3-Quinuclidinyl di(2-thienyl)glycolate is excreted through urine and has been found to be effective against various types of human cancers. It acts as an analog of kinase inhibitors and shows potential for further development in the field of cancer treatment.

<p>6-Desmethyl-6-methylhydroxy etoricoxib N1-oxide is a high purity drug product. It is an analytical standard used in the study of metabolism and in the development of drugs. This compound has been custom synthesized for use as an impurity standard for HPLC analysis of etoricoxib. 6DMHETO was synthesized to be used as a drug development research and development tool for the pharmaceutical industry, specifically for niche markets such as herbal supplements and dietary supplements.</p>

<p>Methyl 1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-alpha-D-glucopyranoside is an impurity of Dapagliflozin.</p>

Betanidine or betanidine is a glycosidic dye or pigment responsible to provide their color to the plant. It belongs to the family of betalain and is used as coloring agent in the food industry. Betadinine is also involved in the in the metabolism of betalains via tyrosinase regulation. It has high antioxidant properties and in certains studies in mice it has been proved to be involved in the regulation of blood glucose levels.

<p>Aceclofenac ethyl ester is a prodrug of diclofenac. It is a non-steroidal anti-inflammatory drug that alleviates the symptoms of pain, stiffness, and swelling. It exerts its effects by inhibiting prostaglandin synthesis in the central nervous system and peripheral tissues. Aceclofenac ethyl ester has minimal systemic absorption when administered orally, which reduces the risk of side effects such as stomach upset and kidney damage. The pharmacopoeia provides an efficient method for preparing this compound by reacting diclofenac with magnesium stearate in a solvent containing an organic amine or alcohol at temperatures below 50°C (122°F). Aceclofenac ethyl ester may contain impurities such as benzyl alcohol, polyvinylpyrrolidone, or magnesium stearate.</p>

Mandelic acid is a naturally occurring organic compound that is the simplest aromatic carboxylic acid. It is used as an intermediate in chemical synthesis, and as a reagent in analytical chemistry. Mandelic acid can be produced synthetically by the oxidation of benzaldehyde or benzoic acid. Mandelic acid has been shown to inhibit the metabolism of many drugs, including diazepam, phenobarbital and propranolol. It also shows anti-inflammatory effects due to its ability to inhibit prostaglandin synthesis.

<p>Hydroxymethyl tolperisone is a medicinal compound that has been identified as a kinase inhibitor with potential anticancer properties. It has shown promising results in inhibiting the growth of leukemia cells and tumor cell lines in human studies. Hydroxymethyl tolperisone works by interfering with protein synthesis, disrupting the cell cycle, and inducing apoptosis in cancer cells. This compound has also been found to be effective against various types of cancer, including breast, lung, and colon cancer. Hydroxymethyl tolperisone is an analog of tolperisone, a muscle relaxant that is excreted primarily through urine. The use of this compound as an anticancer agent is still under investigation, but it holds great promise for the future of cancer treatment.</p>

Please enquire for more information about (S)-Ibu-phox including the price, delivery time and more detailed product information at the technical inquiry form on this page

<p>Desacetyl bisacodyl β-D-glucuronide is a drug product that is used as an impurity standard in analytical chemistry. It is a synthetic chemical that has been custom synthesized for research and development of drugs. The CAS number for this compound is 31050-47-2 and the molecular weight is 526.25 g/mol. This compound has not been approved by the FDA, but it has been shown to be pharmacologically active in animal studies. Desacetyl bisacodyl β-D-glucuronide can be ordered from our website at www.customsynthesislab.com</p>

Quetiapine ep impurity J is a drug product that is custom synthesized to meet the needs of our clients. It can be used for analytical or metabolite identification purposes, as well as research and development. Quetiapine ep impurity J is a metabolite of quetiapine, which is a drug product that falls under the CAS No. 2250242-46-5. We offer high purity and analytical standards for this product and can provide a Metabolism studies report on request. Quetiapine ep impurity J is not listed in the pharmacopoeia and can only be obtained through synthesis. This product also has niche applications in synthetic chemistry research, as well as HPLC standards available on request.

Fensulfothion oxon sulfide is a drug product that can be used as an analytical reference material. It has been shown to be metabolized in animal studies. The metabolite, fensulfothion sulfoxide, can be synthesized from fensulfothion oxon sulfide and is a standard impurity in the synthetic process. Fensulfothion oxon sulfide is used in drug development and research and development to establish pharmacopoeia standards for HPLC purity requirement.

10-Oxo mirtazapine is a metabolite of the antidepressant drug mirtazapine. It is an impurity in the HPLC standard for mirtazapine and has been shown to be pharmacologically active in animal models. 10-Oxo mirtazapine has also been found to be an impurity in other drugs, such as fluoxetine hydrochloride, but it is not known if it has any activity.

<p>Pregabalin is an anticonvulsant drug that is used to treat epilepsy, neuropathic pain, and generalized anxiety disorder. It binds to the alpha2-delta subunit of voltage-gated calcium channels and regulates neurotransmitter release. Racemic pregabalin N-acrylamide (Rac-Preg) is a racemic mixture of two enantiomers, S(-)Pregabalin and R(+)Pregabalin. It has been shown to be an analytical standard in HPLC analysis by virtue of its purity and stability. Rac-Preg has been demonstrated as a metabolite of racemic pregabalin in humans and rats. Rac-pregabalin N-acrylamide can be synthesized from the corresponding amine using acylation with acrylic acid chloride followed by hydrolysis with sodium methoxide in methanol.</p>