APIs for research and impurities

Eltrombopag methyl ester is a drug product that is used in the treatment of thrombocytopenia. It is an HPLC standard and an analytical impurity. Eltrombopag methyl ester's CAS number is 1246929-01-0 and it has a molecular weight of 311.03 g/mol. The purity of Eltrombopag methyl ester is 99%.

<p>3-Des(2-methylpropyl)-3-N-butyl tetrabenazine is a synthetic drug product that has been studied in metabolism studies. It is an API impurity with the CAS No. 19328-35-9 and is a custom synthesis. 3DMBT has an analytical standard that can be used to measure its purity and quality. This drug product can be used for research and development, niche, or as a HPLC standard. The purity level of this drug is high and it complies with pharmacopoeia standards.</p>

This compound is an analytical reference standard that is used in drug development, research and analysis. It is a high purity chemical that has been synthesized from natural and synthetic sources. This chemical was originally developed as an API impurity for the drug product, but has since been adopted as a pharmacopoeia standard for HPLC and LC-MS/MS. The CAS number for this compound is 1798043-12-5.

Please enquire for more information about Dihydro artemisinin tetrahydrofuran acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Prothoate is a medicinal analog that acts as an inhibitor of kinases. It has been shown to have anticancer properties and can induce apoptosis in cancer cells. Prothoate has been found to be effective against various types of tumors, including those of the lung and breast. This inhibitor has been isolated from Chinese urine and can target specific proteins involved in tumor growth and progression. Prothoate may offer a promising new approach for the treatment of cancer.

<p>(E,Z)-Epalrestat methyl ester is a drug product that is custom-synthesized for research and development purposes. It is a natural metabolite of (E,Z)-epalrestat acid. The chemical name for this compound is 3-[(2-chlorophenyl)methyl]-N-(1H-indol-3-ylmethylene)malonamide. The molecular weight of this compound is 284.87 g/mol and it has an empirical formula of C24H27ClN2O2. It has been found to inhibit the activity of phosphodiesterase (PDE), which plays a role in the breakdown of cyclic nucleotides such as cAMP and cGMP. This product has high purity and analytical data that can be used for metabolism studies or clinical trials.</p>

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Pf9 tetrasodium is a high purity, HPLC standard. It is used as an analytical standard in metabolism studies and as a synthetic impurity standard. Pf9 tetrasodium is also used in drug development research and development to create new drugs and to optimize the production of existing drugs. This product is sold in quantities of 100 grams or more. Pf9 tetrasodium has CAS number 851265-78-6.

Atorvastatin lactam lactone is a synthetic drug product that has been used in the research and development of atorvastatin. It is an impurity standard for atorvastatin and has been shown to be the major metabolite of atorvastatin. Atorvastatin lactam lactone is a white powder with a melting point of 122-124°C, soluble in ethanol and acetone, but insoluble in water. This substance is not found naturally in any plants or animals, but it can be synthesized by reacting 3-hydroxyatorvastatin (3HA) with lithium hydroxide.

<p>1,3-Bis(9H-carbazol-4-yloxy)-2-propanol is a metabolite of carvedilol. It is not active as a drug, but may have pharmacological effects. 1,3-Bis(9H-carbazol-4-yloxy)-2-propanol is used as an impurity standard for HPLC analysis of carvedilol in the pharmaceutical industry.</p>

(2R,2R,Trans)-saxagliptin is a drug product that is synthesized using natural ingredients. It is a custom synthesis and has high purity. The CAS number for this compound is 1564266-03-0. (2R,2R,Trans)-saxagliptin is an analytical standard that can be used in metabolism studies and drug development. This compound has been shown to be metabolized in humans through the cytochrome P450 system or glucuronidation pathways. Metabolites of this compound have been identified as 2-(3-hydroxyphenyl)benzothiazole and 2-(3-hydroxyphenyl)benzoxazole. Impurities have been found in the HPLC standard for this compound at concentrations of 0.0025%.

<p>Gomphrenin I is an analog of a human protein that has been found to have potent anticancer properties. It works by inhibiting kinases, which are enzymes involved in cell signaling pathways that can contribute to the growth and survival of cancer cells. Gomphrenin I has been shown to induce apoptosis, or programmed cell death, in cancer cells and has demonstrated efficacy against various tumor types. This medicinal compound is a promising inhibitor for kinases and may hold potential as a therapeutic agent for cancer treatment. Gomphrenin I has been isolated from Chinese herbal medicine and can be detected in urine samples after ingestion.</p>

2-(((Hydroxy-4-methyloctyl)oxy)carbonyl)cyclohexanecarboxylic acid is a metabolite of the plasticiser diethyl phthalate. It is found in urine samples and can be quantified by liquid chromatography with electrospray ionization mass spectrometry. 2-(((Hydroxy-4-methyloctyl)oxy)carbonyl)cyclohexanecarboxylic acid has been shown to cause cancer in animals and newborns, as well as to inhibit male reproductive development in humans. This compound can be detected in the population at a dilution of 1:100,000.

Trioxifene is an analog of tamoxifen, a selective estrogen receptor modulator (SERM) that has been used in breast cancer treatment. Trioxifene has demonstrated potent anticancer activity by inducing apoptosis in various cancer cells, including Chinese hamster ovary and human tumor cells. It acts as an inhibitor of protein kinases, which play a crucial role in cell proliferation and survival. Trioxifene has also shown potential medicinal benefits as a urinary excretion inhibitor of certain proteins and enzymes involved in cancer progression. With its potent anticancer properties, Trioxifene has become a promising candidate for the development of novel cancer therapies.

<p>Imipramine N-oxide hydrate is a drug product that is used in the synthesis of other drugs. It has been shown to be metabolized by cytochrome P450 enzymes and glucuronidases, as well as oxidative metabolites. Imipramine N-oxide hydrate is a metabolite of imipramine.</p>

<p>(aR)-a-Methyl-N-[3-[4-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethanamine is a synthetic drug product that is used in research and development. It has been shown to have an analytical purity of 99.8%.</p>

2-(((4-Methyl-7-oxyooctyl)oxy)carbonyl)cyclohexanecarboxylic acid (2MEOCA) is a metabolite of progesterone which has been detected in human urine. 2MEOCA can be found in the environment as a result of industrial production or from the use of materials containing progesterone in consumer products, such as plastics and personal care products. It has been postulated that 2MEOCA may be an analytical biomarker for exposure to progesterone and its metabolites. 2MEOCA is stable in urine samples stored at room temperature for at least 24 hours and can be measured by a high performance liquid chromatography - mass spectrometry (HPLC-MS/MS) method. The median concentration of 2MEOCA was found to be 0.3 ng/mL in on-line pooled human urine samples, with concentrations ranging from 0.1 ng/mL

1-[4-[4-(2,3-Dichlorophenyl)piperazin-1-yl]butyl]-7-hydroxy-1,2,3,4-tetrahydro-carbostyril (1HHC) is a synthetic drug that is used as a research tool in the study of metabolism. It has been shown to be metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. 1HHC also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.

<p>Please enquire for more information about 4-Desmethyl 5-methyl vortioxetine hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

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