APIs for research and impurities
Active Pharmaceutical Ingredients (APIs) are the substances in drugs responsible for their therapeutic effects. In this section, you will find a wide variety of APIs intended for research use. These compounds are essential for the development, testing, and validation of new pharmaceutical formulations. CymitQuimica offers high-quality APIs to support research in drug discovery and development.
Subcategories of "APIs for research and impurities"
- Aminoacids and derivatives(12,348 products)
- Anthraquinones and derivatives(405 products)
- Benzimidazole and Imidazole Derivatives(10,463 products)
- Benzodiazepine Derivatives(335 products)
- Carbohydrates and glycoconjugates(5,048 products)
- Esters and Derivatives(42,305 products)
- Fatty Acids and Lypidic Derivatives(32,454 products)
- Flavonoids and Polyphenols(17,098 products)
- Free Radicals and Oxidant/Reducing Agents(214 products)
- Ketones and derivatives(2,402 products)
- Natural and semi-synthetic antibiotics(6,398 products)
- Nitriles and Cyano Derivatives(3,070 products)
- Nitrosamines and Derivatives(55 products)
- Nucleosides and Nucleotides(3,486 products)
- Organic Phosphates and Phosphonates(1,202 products)
- Organic Sulphonates and Sulphates(10,447 products)
- Organometallics(4,424 products)
- Others(6,322 products)
- Peptides and Proteins(3,151 products)
- Polymers and Derivatives(100 products)
- Purines and Pyrimidine Derivatives(8,957 products)
- Quinazoline and Quinoline Derivatives(66,131 products)
- Quinones and Derivatives(24,376 products)
- Salts and Derivatives of Active Pharmaceutical Ingredients (API)(80,360 products)
- Steroids and Derivatives(4,975 products)
- Sulfonamides and Derivatives(2,606 products)
- Terpenoids and Derivatives(3,858 products)
- Thiazolidinediones and Thiopyrans(2,755 products)
- β-Adrenergic Compounds(231 products)
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Found 57677 products of "APIs for research and impurities"
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D-Ribose-L-cysteine
CAS:D-Ribose-L-cysteine is a combination of D-ribose and L-cysteine. It is used for the treatment of bowel disease, radiation injury, pentobarbital sodium induced ileus, atherosclerotic lesion, oral hypoglycaemic, neuronal death, psychotic disorder in AIDS patients and active antiretroviral therapy. D-Ribose-L-cysteine has been shown to decrease ATP levels and increase histological damage in v79 cells. D-Ribose-L-cysteine has also been shown to have a protective effect on hamster V79 cells against inflammatory bowel disease by decreasing the release of inflammatory cytokines.
Formula:C8H15NO6SPurity:Min. 95%Molecular weight:253.28 g/molAvanafil 5’-desmethylpyrimidyl 5’-acid
CAS:Avanafil 5'-desmethylpyrimidyl 5'-acid is a kinase inhibitor that has been shown to have anti-cancer properties. It inhibits kinases, which are enzymes involved in cell signaling pathways, and has been shown to inhibit the growth of cancer cells in vitro. Avanafil 5'-desmethylpyrimidyl 5'-acid may be used in combination with other drugs, such as rifampicin or methotrexate, for the treatment of cancer. Additionally, it has been found to induce apoptosis (programmed cell death) in human tumor cells. Chinese medicine has also used avanafil 5'-desmethylpyrimidyl 5'-acid analogs such as astaxanthin for its health benefits. This drug is excreted primarily through urine and shows promise as a potential inhibitor for various diseases.Formula:C18H21ClN4O4Purity:Min. 95%Molecular weight:392.8 g/mol1,2,3,4-Tetrahydro-4,6,7-isoquinolinetriol hydrochloride
CAS:1,2,3,4-Tetrahydro-4,6,7-isoquinolinetriol hydrochloride is a drug product. It is a synthetic compound that is metabolized to form metabolites. The natural product was isolated from an extract of the roots of Valeriana officinalis L. and has been used as a sedative and hypnotic in traditional medicine. 1,2,3,4-Tetrahydro-4,6,7-isoquinolinetriol hydrochloride has also been shown to have anti-inflammatory activities in human chondrocytes. This drug product is used in research and development for the treatment of neurodegenerative diseases such as Parkinson's disease.Formula:C9H12ClNO3Purity:Min. 95%Molecular weight:217.65 g/mol2-Methyl-3,4-dimethoxy pyridine hydrochloride
CAS:2-Methyl-3,4-dimethoxy pyridine hydrochloride is an analytical standard that is used as a reference compound in the pharmaceutical industry to identify impurities in drug products. It also has a niche use as an API impurity and HPLC standard. 2-Methyl-3,4-dimethoxy pyridine hydrochloride is used as an intermediate for the synthesis of other drugs, including benzodiazepines and beta blockers. It is also used in research and development for its high purity. This chemical is natural or synthetic in origin but can be custom synthesized to meet specific requirements. 2-Methyl-3,4-dimethoxy pyridine hydrochloride also has CAS number 1210824-88-6.Formula:C8H11NO2HClPurity:Min. 95%Molecular weight:189.64 g/molCetirizine amide dihydrochloride
CAS:Cetirizine amide dihydrochloride is a drug product that has been custom synthesized for research and development. It is a high purity, analytical grade material that is natural and synthetic in origin. Cetirizine amide dihydrochloride's CAS number is 200707-85-3. The impurity standard for this material is HPLC grade. This drug product can be found on the United States Pharmacopoeia (USP) and the European Pharmacopoeia (EP). Cetirizine amide dihydrochloride has been used in metabolism studies and as a pharmacopoeia reference standard.Formula:C21H28Cl3N3O2Purity:Min. 95%Molecular weight:460.82 g/molEthylene terephthalate cyclic pentamer-d20
CAS:The ethylene terephthalate cyclic pentamer is a polyester that is used in the manufacture of polyester fibers and polyester films. It is extracted from the raw material, which is a mixture of dimethyl terephthalate, ethylene glycol, and 1,4-butanediol. The extruder heats the raw material to 240°C in order to convert it into its liquid form. The crystallization process takes place at room temperature and produces a white solid product called oligomer. Extraction removes impurities from the oligomer by washing it with water. Linear polyester is obtained by heating the purified oligomer at 260°C for 40 minutes, while extruded polyester undergoes a heat treatment of 230°C for 20 minutes. Extrusion produces pellets that are then processed into filaments or sheets.Formula:C50H20D20O20Purity:Min. 95%Molecular weight:980.96 g/molN-Desmethyl sorafenib
CAS:N-desmethyl sorafenib is an analytical standard for the HPLC assay of sorafenib. It is a metabolite of sorafenib, which is a drug used in the treatment of cancer. It has been shown to inhibit protein synthesis and cell growth in vitro and in vivo. N-desmethyl sorafenib has been shown to inhibit the activity of methionine adenosyltransferase, leading to inhibition of DNA synthesis. The chemical properties are similar to those of other drugs that have been approved by the US Food and Drug Administration.Formula:C20H14ClF3N4O3Purity:Min. 95%Molecular weight:450.80 g/molPethoxamid
CAS:Pethoxamid is a kinase inhibitor that has been used in traditional Chinese medicine for its medicinal properties. It targets mutant kinases that are involved in the growth and proliferation of cancer cells, making it a potential anti-cancer drug. Pethoxamid has been shown to inhibit the growth of human tumor cells in vitro, inducing apoptosis and reducing cell viability. It also has potential as an inhibitor of various proteins involved in cancer progression, making it a promising candidate for future cancer therapies. Pethoxamid may have significant implications for the treatment of cancer and could be an important tool in fighting this devastating disease.Formula:C16H22ClNO2Purity:Min. 95%Molecular weight:295.8 g/molQuetiapine ep impurity J
CAS:Controlled ProductQuetiapine ep impurity J is a drug product that is custom synthesized to meet the needs of our clients. It can be used for analytical or metabolite identification purposes, as well as research and development. Quetiapine ep impurity J is a metabolite of quetiapine, which is a drug product that falls under the CAS No. 2250242-46-5. We offer high purity and analytical standards for this product and can provide a Metabolism studies report on request. Quetiapine ep impurity J is not listed in the pharmacopoeia and can only be obtained through synthesis. This product also has niche applications in synthetic chemistry research, as well as HPLC standards available on request.Formula:C25H34ClN3O4SPurity:Min. 95%Molecular weight:508.1 g/molCycrimine hydrochloride
CAS:Cycrimine hydrochloride is a molecule that is used as an anticholinergic drug. It has been shown to be effective in humans, with a half life of 3 hours and a duration of action of 8 hours. Cycrimin hydrochloride is also used as a diagnostic agent for irritant contact dermatitis and may be useful in the diagnosis of other allergic reactions. The molecule is also used as a diagnostic aid for cardiac arrhythmias.
Formula:C19H30ClNOPurity:Min. 95%Molecular weight:323.9 g/molDihydro lafutidine
CAS:Dihydro lafutidine is a drug product that is used in the treatment of acid-related disorders. It is an analytical standard and impurity control compound for HPLC. Dihydro lafutidine has been shown to inhibit the production of gastric acid by blocking the histamine H2 receptor, which is involved in regulating stomach pH. It also inhibits the growth of Helicobacter pylori, which may be due to its ability to bind to bacterial 16S ribosomal RNA and inhibit protein synthesis.Formula:C22H31N3O4SPurity:Min. 95%Molecular weight:433.60 g/molPolyethylene glycol monoisotridecyl ether
CAS:Polyethylene glycol monoisotridecyl ether (PEG-DTAE) is a polymer that can be used as an antimicrobial agent. It is active against Gram-positive bacteria but not against Gram-negative bacteria. PEG-DTAE has anti-angiogenic effects, which may be due to its ability to inhibit the growth of new blood vessels and thereby prevent the spread of infection. In vitro assays have shown that PEG-DTAE can induce cell lysis and hemolysis in test samples. PEG-DTAE has been shown to have hemolytic activity in vivo in rats, with histology sections showing inflammation and necrosis in the spleen and liver. This polymer also causes symptoms such as fever, chills, rigors, and hypotension in patients with chronic renal failure who are undergoing dialysis.
Formula:C30H62O10Purity:Min. 95%Molecular weight:582.8 g/mol6,7-Dimethoxy-2-[4-[(tetrahydro-2-furanyl)carbonyl]-1-piperazinyl]-4(3H)-quinazolinone
CAS:6,7-Dimethoxy-2-[4-[(tetrahydro-2-furanyl)carbonyl]-1-piperazinyl]-4(3H)-quinazolinone is a drug product. It is an analytical standard for the impurity of CAS No. 1177261-73-2. This compound has been synthesized by custom synthesis and its purity is high. The compound has been used in research and development of drugs, pharmacopoeia, HPLC standards, and other related fields.Formula:C19H24N4O5Purity:Min. 95%Molecular weight:388.42 g/mol5-(4-Fluorobenzyl)-2,4-thiazolidinedione
CAS:Pioglitazone is a thiazolidinedione drug that is used to treat type 2 diabetes. It is an anti-diabetic drug that works by increasing the sensitivity of cells to insulin, thereby lowering blood sugar levels. Pioglitazone has been found to have impurities in bulk batches that are detectable by HPLC. This impurity is a pyridine derivative and can be removed by recrystallization or chromatography.Formula:C10H8FNO2SPurity:Min. 95%Molecular weight:225.24 g/mol[4-L-Glutamic Acid]-desmopressin
4-L-Glutamic Acid]-desmopressin is an analytical standard that is used to calibrate HPLC systems. This product is a high purity, synthetic, and drug development API impurity that can be used as a drug product or impurity standard. It is also available as an HPLC standard, niche, and custom synthesis. 4-L-Glutamic Acid]-desmopressin has been shown to have pharmacopoeia and CAS No.Purity:Min. 95%5-Oxo atorvastatin
CAS:5-Oxo atorvastatin is an impurity standard for atorvastatin. It is a synthetic metabolite that has been observed in the urine of patients receiving atorvastatin. 5-Oxo atorvastatin can be used as a reference compound to calibrate HPLC measurements and as an analytical standard in pharmacopoeia testing.Formula:C33H33FN2O5Purity:Min. 95%Molecular weight:556.6 g/molTetrahydro erlotinib
CAS:Tetrahydro erlotinib is a drug product that is used in the treatment of non-small cell lung cancer. Tetrahydro erlotinib is an inhibitor of tyrosine kinases and can act on epidermal growth factor receptors, vascular endothelial growth factor receptors, and platelet-derived growth factor receptors. It has been shown to inhibit the proliferation of tumor cells in vitro and in vivo. Tetrahydro erlotinib is metabolized by CYP3A4 to form two major metabolites, which have similar pharmacological properties as the parent compound. These metabolites are eliminated from the body primarily through urinary excretion. Tetrahydro erlotinib may be toxic to the liver and kidneys due to its ability to induce hepatotoxicity and nephrotoxicity.Formula:C22H27N3O4Purity:Min. 95%Molecular weight:397.5 g/molIsoxadifen
CAS:Isoxadifen is a medicinal compound that has been shown to have potent anticancer properties. It works by inhibiting kinases, which are enzymes that play a key role in cell cycle regulation and apoptosis. Isoxadifen has been found to be effective against various types of cancer, including human bladder cancer and prostate cancer. In Chinese urine samples, it was found to be an inhibitor of protein kinases associated with tumor growth. This compound also induces apoptosis in cancer cells, leading to their death. Isoxadifen is a promising candidate for the development of new anticancer drugs due to its potent inhibitory effects on tumor growth and its ability to induce cell death in cancer cells.Formula:C16H13NO3Purity:Min. 95%Molecular weight:267.28 g/molAbacavir 5’-4-chloro-6-methylpyrimidine-2,5-diamine
CAS:Abacavir is an antiviral drug that is used to treat HIV/AIDS. It is a prodrug that is converted to the active form, 6-amino-9-(1,3-dihydroxypropyl)purine riboside, in the liver. Abacavir is metabolized by cytochrome P450 enzymes and sulfotransferases. The metabolism of abacavir involves two major pathways: (1) formation of a reactive intermediate that can cause DNA damage and (2) oxidative metabolism to form metabolites that are excreted in urine. This drug product has been developed by custom synthesis and has been shown to be pure with high quality standards.Formula:C18H21ClN10OPurity:Min. 95%Molecular weight:428.9 g/molBis-[[2-[1-methylamino-2-nitroethenamine]ethyl]thio]methane
CAS:Bis-[[2-[1-methylamino-2-nitroethenamine]ethyl]thio]methane is a drug product that has been synthesized for research and development. This product is an analytical standard and is used in metabolism studies, natural products, drug development, and the preparation of impurity standards. The CAS number for this product is 1331637-48-9. This product is a synthetic compound that has not been approved by the FDA or any other regulatory agency. It can be shipped to US destinations only.Formula:C11H22N6O4S2Purity:Min. 95%Molecular weight:366.46 g/mol
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