APIs for research and impurities

Olsalazine sodium impurity B is a synthetic compound that is used in the production of Olsalazine sodium. It is one of the metabolites of olsalazine and has been found to be more potent than olsalazine sodium. Olsalazine sodium impurity B is purified by HPLC and characterized by analytical methods such as UV, IR, melting point, NMR, and mass spectrometry. Impurity standard for this compound has not been established yet.

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N-[4-[2-[[(2R)-2-Hydroxy-2-phenylethyl]amino]ethyl]phenyl]-acetamide is a synthetic drug product that belongs to the class of drugs called acetamides. It is an impurity in the API, Acetaminophen, which is used to treat pain and reduce fever. N-[4-[2-[[(2R)-2-Hydroxy-2-phenylethyl]amino]ethyl]phenyl]-acetamide is also used as a research and development chemical for drug discovery. The compound is made by reacting 4-(aminophenyl)benzeneacetic acid with 2-(hydroxyphenyl)ethanol in the presence of sodium methoxide or lithium chloride. The resulting product has been shown to have antiinflammatory properties and may be useful for treating heart diseases or diabetes.

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rac-N-Desisopropyl-N-ethyl acebutolol is a synthetic drug product. It is an analytical standard for the impurity, acebutolol, and is metabolized by cytochrome P450 3A4 to form the major metabolite, N-desisopropyl acebutolol. rac-N-Desisopropyl-N-ethyl acebutolol is a research and development product that can be custom synthesized to meet specific needs. It has been shown to have antihypertensive properties in rats and monkeys. This product is not intended for human use.

3-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]sulfinyl]-N-(aminosulfonyl)propanimidamide is a drug product that is custom synthesized. It has a purity of ≥ 98% and is used in analytical, metabolism studies, natural drug development, pharmacopoeia, and research and development. 3-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]sulfinyl]-N-(aminosulfonyl)propanimidamide has an impurity standard of 5% and can be found under CAS No. 90237-03-9.

(2S,3aS,7aR)-octahydro-1H-indole-2-carboxylic acid is a metabolite of the drug product, indomethacin. It has not been identified in any natural sources. (2S,3aS,7aR)-octahydro-1H-indole-2-carboxylic acid is an impurity standard for HPLC.

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2,3,6,7-Tetrachlorobiphenylene is a potent inhibitor of kinases that are involved in cancer cell growth and proliferation. It is an analog of tolvaptan, a drug used to treat hyponatremia by increasing urine output. This compound has been shown to induce apoptosis in cancer cells and inhibit tumor growth. Studies have found that 2,3,6,7-Tetrachlorobiphenylene inhibits the activity of human protein kinases and may be effective against various types of cancer. This Chinese compound has promising anticancer properties and could potentially be used as a therapeutic agent for cancer treatment.

Sulfamethoxypyridazine-d3 is a compound that has been shown to have anti-trophic and transport properties. It has been shown to be capable of binding with organic pollutants, including benzothiazoles, and has the potential to be used in screening for these compounds. Sulfamethoxypyridazine-d3 has also been shown to inhibit the growth of organisms, such as bacteria and fungi. This compound is not absorbed by humans or animals when administered orally, but can be transferred through skin contact. In vitro studies show that it is not toxic at concentrations of up to 100 μg/mL and does not cause irritation in skin or eye irritation tests.

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Mdl 72832 hydrochloride is a ligand that modulates the activity of nerve cells. It has been shown to activate and synergistically enhance the effects of nerve growth factor (NGF) and acetylcholine on neurons. Mdl 72832 hydrochloride also increases the synthesis and release of melanocortins, which are neurotransmitters that are involved in regulating appetite, mood, and pain sensation. Mdl 72832 hydrochloride may be a potential nootropic agent for the treatment of neurodegenerative diseases such as Alzheimer's disease or Parkinson's disease.

Lisinopril EP Impurity I is an impurity of the drug lisinopril. It is a natural product that has been synthesized for use as an analytical standard for pharmacological research and development. Lisinopril EP Impurity I is a synthetic compound that was custom-synthesized from amino acid derivatives and has been used in the manufacture of pharmaceuticals as an impurity standard, including as a high purity HPLC standard. This impurity has been shown to be less toxic than other lisinopril epimerization products, such as lisinopril epimerization product II, which can cause renal toxicity. Lisinopril EP Impurity I also has anti-inflammatory effects and can inhibit LPS-induced production of nitric oxide by macrophages.

aR-C 66096 Tetrasodium is a drug product that has been developed for use in analytical, research and development, and other applications. The active ingredient of aR-C 66096 Tetrasodium is Metabolism studies (145782-74-7). It is a natural API impurity with CAS No. 145782-74-7. The impurity standard of this compound is Synthetic (145782-74-7). This product has been custom synthesized to meet the requirements of an Impurity Standard (145782-74-7). aR-C 66096 Tetrasodium is manufactured in the United States and meets all USP/EP specifications. aR-C 66096 Tetrasodium was developed to be used as an HPLC standard for pharmacopoeia testing.

Pinaverium bromide impurity 11 is a drug product that is used in the development of new drugs. It is an analytical standard for pharmacopoeia and research purposes. The chemical name for Pinaverium bromide impurity 11 is 2-Bromo-6-nitrobenzimidazole, CAS No. 1970218-70-2, which can be found in the NIST Mass Spectral Library. This compound has a molecular weight of 226.12 and melting point of 191°C (decomposes). It has been custom synthesized by our company to meet the requirements of customers who need this specific impurity for their drug development or research and development.

4-(5-((2-Chloroethyl)ao)-1-methyl-1H-benzo[D]imidazol-2-yl butanoic acid is an analog of a potent anticancer drug that targets kinases involved in cancer cell growth and survival. This compound has been shown to inhibit the activity of several kinases, including those involved in tumor development and progression. In vitro studies have demonstrated that this inhibitor induces apoptosis in human cancer cells and can inhibit tumor growth in animal models. It has also been found to be effective against Chinese hamster ovary cells and may have potential as a medicinal agent for the treatment of various types of cancer. Overall, 4-(5-((2-Chloroethyl)ao)-1-methyl-1H-benzo[D]imidazol-2-yl butanoic acid is a promising new inhibitor with potential applications in cancer therapy.

3-Hydroxy deoxy dihydro artemisinin is a drug product that is an analytical standard for the determination of artemisinin in natural and synthetic samples. It is a metabolite of artemisinin, which is a natural compound extracted from Artemisia annua L. (Asteraceae). 3-Hydroxy deoxy dihydro artemisinin is also an impurity found in commercial preparations of artemisinins. 3-Hydroxy deoxy dihydroartemisinin has been used as an API impurity standard, and has been synthesized as part of drug development research and development. The purity of this substance was determined by HPLC analysis, and it complies with the pharmacopoeia requirements.

Imidapril tert-butyl ester is a drug product that is custom synthesized. It has a purity of >98% and analytical data available. Imidapril has been shown to be metabolized in vivo through hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. There is also an impurity standard for this compound. Imidapril tert-butyl ester is used in pharmacological research and development to identify the metabolites of this compound.

Dinosam is a medicinal compound that has been found to possess potent anticancer properties. It is an analog of a natural product isolated from Chinese urine and acts as an inhibitor of kinases, which are proteins involved in the regulation of cell growth and division. Dinosam has been shown to induce apoptosis (programmed cell death) in cancer cells, making it a promising candidate for cancer therapy. In addition to its anticancer effects, Dinosam has also been found to have potential as an inhibitor of other human kinases. Its unique structure and mechanism of action make it a valuable tool for the development of new kinase inhibitors with therapeutic potential.