Amino Acids (AA)

<p>Applications 1-Methoxy-4-(1E)-1-propen-1-ylbenzene is a component of essential oils extracted from natural sources. It is also a possible inhibitor of protein kinase CK2α and CK2α’.<br>References Liang, Zhi-yuan, et al.: Shizhen Guoyi Guoyao, 25(7), 1602-1604 (2014);Benelli, Giovanni, et al.: Indus. Crops and Prod., 124, 236-243 (2018);Baier, Andrea, et al.: Phytochem., 136, 39-45 (2017)<br></p>

<p>Applications 3-Formyl-5-methylbenzoic Acid<br></p>

<p>Stability Very Volatile<br>Applications 3-Methylfuran is a volatile organic compound (VOCs) used as a potential non-intrusive tool for screening of lung cancer.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References McWilliams, et al.: Curr. Oncol. Rep., 4, 487 (2002), Buszewski, B., et al.: Biomed. Chromatogr., 21, 553 (2007), Ligor, T., et al.: J. Breath. Res., 1, 1 (2007),<br></p>

<p>Applications VINYLTRIS(2-METHOXYETHOXY)SILANE (cas# 1067-53-4) is a useful research chemical.<br></p>

<p>Applications 4-Chloro-benzoic Acid 1-(4-Methoxyphenyl)hydrazide Hydrochloride is a derivative of (4-Methoxyphenyl)hydrazine Hydrochloride (M265880). It is a useful synthetic intermediate for the preparation of Indomethacin (I641000); a potent, time-dependent, nonselective inhibitor of the cyclooxygenase enzymes COX-1 and COX-2.<br>References Blobaum, Anna L., et al.: ACS Med. Chem. Lett., 4(5), 486-490 (2013); Prusakiewicz, Jeffery J., et al.: Biochemistry, 43(49), 15439-15445 (2004)<br></p>

<p>Stability Hygroscopic, Moisture Sensitive<br>Applications Hexahydro-4-methylphthalic Anhydride, can be used in the mixture of other isomers nanofiber supported 3D interconnected BN nanosheets for epoxy nanocomposites with ultrahigh thermal management capability<br>References Chen, J., et al.: Adv. Funct. Material., 27, 5 (2017)<br></p>

<p>Applications N-Methyl-2,4-dinitroaniline-d3 (cas# 91808-45-6) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Stability Light sensitive, Temperature Sensitive<br>Applications 3-Methyl-1,5-pentanediol Diacrylate is a useful chemical reagent.<br></p>

<p>Stability Extremely Hygroscopic<br>Applications Labelled L-Arginine (A769500). An essential amino acid for human development. Precursor for nitric oxide. Ammonia detoxicant (hepatic failure); diagnostic aid (pituitary function).<br>References Miura, T., et al.: Anal. Biochem., 139, 432 (1984), Jones, et al.: Adv. Enzyme Regul., 9, 19 (1970), Borders, C.L., et al.: Protein. Sci., 3, 541 (1994),<br></p>

<p>Applications N-Boc-4-hydroxypiperidine is a 4-hydroxypyridine with a boc protecting group used in the preparation of neurologically active agents and other pharmaceutical compounds.<br>References Kwon, Y.E. et al.: Bioorg. Med. Chem., 15, 6596 (2007); Knutsen, L.J.S. et al.: J. Med. Chem., 42, 3463 (1999);<br></p>

<p>M03001 - H-Gly-OH</p>

<p>Impurity Levothyroxine beta-Hydroxy Impurity / Levothyroxine beta-Hydroxy T4 Impurity<br>Applications It has been prepared for testing as possible antithyroid. It showed some thyromimetic activity.<br>References Wawzone, S., et al.: J. Med. Chem., 6, 442 (1963),<br></p>

<p>Applications 9-(N-Methylaminomethyl)anthracene is a reactant that has been used in the synthesis of anthracene-oxyquinoline dyad as a fluorescent indicator for Hg(II).<br>References Praveen, L., et. al.: Tetrahedron Lett., 53, 3951 (2012)<br></p>

<p>Applications Isopropyl 2-bromo-2-methylpropanoate (cas# 51368-55-9) is a useful research chemical.<br></p>

<p>Impurity Imatinib EP Impurity G<br>Applications 1-Methylpiperazine (Imatinib EP Impurity G) is used in the preparation of 2-(4-Methyl-1-piperazinylmethyl)acrylophenone(MPMAP), an antimicrotubular drug. It is a COVID19-related research product.<br>References Mallevais, M.L. et al.: Biochimie, 66, 477 (1984);<br></p>

<p>Applications 5-Oxo-DL-proline-d5 is a labelled cyclized derivative of L-Glutamic Acid (G596960). The pyroglutamate core has potential application for synthesis of novel anti-bacterials.<br>References Mischo A. et al.: ChemBioChem., 13, 1421 (2012); Angelov P. et al.: Org. Biomol. Chem.: 10, 3472 (2012);<br></p>

<p>Stability Hygroscopic<br>Applications 7-CHLORO-L-TRYPTOPHAN (cas# 73945-46-7) is a useful research chemical.<br></p>

<p>Applications 4-Methyl-2-pentanol is used in the synthesis of 4-quinolone derivatives as high-affinity ligands for the brain GABAA receptors. Also used in the preparation of antimycotic imadazoles, as antifungals.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lager, E. et al.: J. Med. Chem., 49, 2526 (2006); Heeres, J. et al.: J. Med. Chem., 22, 1003 (1979);<br></p>

<p>Applications 3,5-Dihydroxy-4-methoxybenzoic Acid is a useful building block in organic synthesis.<br>References Ghosh, Koushik, et al.: Angewandte Chemie, I.E., 55(27), 7821-7825 (2016);Vergne, Fabrice, et al.: Bioorg. &amp; Medi. Chem. Let., 14(18), 4607-4613 (2004)<br></p>

<p>Applications 2-Methylindoline is an intermediate in the production of various indole derivatives<br>References Severino, B., et al.: Bioorg. Med. Chem., 16, 6009 (2008); Zlotos, D., et al.: J. Med. Chem., 52, 826 (2009);<br></p>

<p>Applications Perfluoro(4-methyl-3,6-dioxaoct-7-ene)sulfonyl Fluoride is used as a reagent in the synthesis of novel perfluorinated vinyl ether containing sulfonimide functionality which can be copolymered with tetrafluoroethylene to yield a novel perfluorinated copolymer.<br>References Zhu, S., et al.: Chinese J. Chem., 21, 921 (2003);<br></p>

<p>Applications 4-Methyl-d3-catechol (CAS# 83719-41-9) is a useful isotopically labeled research compound.<br></p>

<p>Stability Hygroscopic<br>Applications A metabolite of 1-methyl-2-thioimidazole (methimazole). It inhibits bone resorption.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Paterson, J.R., et al.: Biochem. Biophys. Res. Comm., 116, 449 (1983), Taurog, A., et al.: Endocrinology, 124, 30 (1989).<br></p>

<p>Impurity Temozolomide USP Related Compound B<br>Applications N'-Methyl-N,N-diphenylurea is used in the stabilization of thermal propellants. Temozolomide USP Related Compound B.<br>References Bohn, M. et al.: Prop. Exp. Pyro.,et al.: 19, 266 (1994); Muthurajan, H. et al.: J. Hazard. Mat., 133, 30 (2006);<br></p>

<p>Applications 2-METHOXY-4-METHYLANILINE (cas# 39538-68-6) is a useful research chemical.<br></p>

<p>Stability Very Hygroscopic<br>Applications A component of elastin. It can be measured in all body fluids as biomarkers for in vivo degradation of matrix tissue elastin in man and animals.<br>References Sato, F., et al.: Clin. Biochem., 39, 746 (2006), Koenders, M., et al.: J. Pathol., 218, 446 (2009), Ma, S. et al.: J. Chrom. Anal. Tech. Biomed. Life Sci., 879, 1893 (2011),<br></p>

<p>Applications Naphthalenecarboxylic acid derivatives known for their antidote activity against urea and other herbicides.<br></p>

<p>Applications Boc-(S)-3-Amino-4-(2,4,5-trifluorophenyl)butyric Acid is a reactant used in the preparation of peptidase IV inhibitors.<br>References Park, W. et al.: Bioorg. Med. Chem. Lett., 21, 1366 (2011);<br></p>

<p>Stability Unstable in methanol solution<br>Applications 4-Chloro-2-methylphenol Sulfate Sodium Salt is a halogenated derivative of o-toluenesulfonate, present in landfill leachates. o-Toluenesulfonate is an analog of the strong organic acid p-Toluenesulfonate.<br>References Riediker, S. et al.: Environ. Sci. Tech., 34, 2156 (2000);<br></p>

<p>Impurity Ciclopirox EP Impurity B/ USP Ciclopirox Related Compound B<br>Applications 6-Cyclohexyl-4-methyl-2H-pyran-2-one (Ciclopirox EP Impurity B) is a a dialkylated pyranone derivative.<br></p>

<p>Applications 5-methoxypentanoic acid (cas# 70160-05-3) is a useful research chemical.<br></p>

<p>Applications MNC is on the metabolic pathway for 2,4-Dinitotoluene degradation.<br>References Spangoord, R.J., et al.: App. and Environ. Microbiology, 57, 11, 3200 (1991)<br></p>

<p>Applications A metabolite common to all triazole fungicides: free triazole, 1,2,4-triazole (T), and its 2 conjugates: triazolylalanine (TA) and triazolylacetic acid (TAA).<br>References Hrudey, S., et al.: Water Sci. Technol., 20, 55 (1988), Froese, K., et al.: Water Res., 33, 1355 (1999), Hengel, M., et al.: J. Agric. Food Chem., 50, 3412 (2002),<br></p>

<p>Applications 5-Methoxyresorcinol (cas# 2174-64-3) is a useful research chemical.<br></p>

<p>Applications 3-Methyl-2-hexanamine HCl Salt is more stable and easier to purify compared to the free base.<br></p>

<p>Applications 3-Methylnonane-2,4-dione is a compound that possesses a butter-like and beany off flavour that is a result of flavour reversion of soya-bean oil. 3-Methylnonane-2,4-dione is also present in Japanese green tea and pressure-cooked hen meat.<br>References Farkaš, P., et al.: Food Chem., 60, 617 (1997); Guth, H. &amp; Grosch, W.: Flav. Chem., No vol. given, 377 (1999); Kumazawa, K. &amp; Masuda, H.: J. Agr. Food Chem., 47, 5169 (1999)<br></p>

<p>Applications D-Lysine, HCl<br></p>

<p>Applications An intermediate in the preparation of Ethosuximide.<br></p>

<p>Applications phenyl(pyridin-4-yl)methyl 4-methyl-2-(pyrimidin-2-yl)-1,3-thiazole-5-carboxylate (cas# 1281055-79-5) is a useful research chemical.<br></p>

<p>Applications Intermediate in the production of anti-cancer quinoline derivatives and antibacterial agents<br>References Zhao, H., et al.: Bioorg. Med. Chem. Lett., 12, 3105 (2002),<br></p>

<p>Applications 6-Methoxy-N2-methylpyridine-2,3-diamine dihydrochloride (cas# 83732-72-3) is a useful research chemical.<br></p>

<p>Applications 2-amino-3-methylbutanamide Hydrochloride is a useful research chemical for the degradation studies of antibiotic MDL 62,879 (GE2270A), and a reagent for peptide synthesis.<br>References Tavecchia, P., et al.: Tetrahedron, 51, 4867 (1995); Gazis, E., et al.: Peptides, Proc. Eur. Symp., 6th, Athens, 1963, 107 (1966)<br></p>

<p>Applications 4-methyl-2-(piperidin-4-yl)pyridine (cas# 1260886-47-2) is a useful research chemical.<br></p>

<p>Applications 2-Amino-6-methylpyrimidin-4(3H)-one (cas# 3977-29-5) is a useful research chemical.<br></p>

<p>Applications [2-(1-methyl-1H-pyrazol-3-yl)-1H-benzimidazol-1-yl]acetic acid (cas# 1171565-50-6) is a useful research chemical.<br></p>

<p>Applications 7,10-Dichloro-2-methoxybenzo[b][1,5]naphthyridine is used in the preparation of pyronaridine.<br>References Li, J., et al.: PCT Int. Appl., 2013:1701510 (2013)<br></p>

<p>Applications 2,2-Dimethoxy-N-methylethanamine is an impurity formed in the synthetic process of Methimazole (M260300), a thiourea antithyroid agent that prevents iodine organification,<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sitar, D.S., et al.: J. Pharmacol. Exp. Ther., 184, 432 (1973), Aboul-Enein, H.Y., et al.: Anal. Profiles Drug Subs., 8, 351 (1979), Cooper, D.S., et al.: N. Engl. J. Med., 311, 1353 (1984), Atterwill, C.K., et al.: Food Chem. Toxicol., 29, 355 (1991),<br></p>

<p>Stability Light Sensitive<br>Applications α-Methacrylic acid is used in chemistry as a stabilizing agent, forming a thin capping layer on the surface of nanoparticles. α-Methacrylic acid is also used as a surfactant, so that control is maintained during nanocrystal growth. α-Methacrylic acid is also used as a chelating agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Peng, W., et al.: J. Cryst. Growth, 279, 454 (2005); Qu, S., et al.: Appl. Phys. Lett., 80, 3605 (2002); Zhao, G., et al.: Phys. C: Supercond., 468, 2317 (2008)<br></p>

<p>Applications 1-[1-(2-methoxyethyl)piperidin-3-yl]methanamine (cas# 936940-49-7) is a useful research chemical.<br></p>

<p>Stability Hygroscopic<br>Applications 4-Chloro-2-methylaniline Hydrochloride (cas# 3165-93-3) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Impurity Lisinopril EP Impurity B/ Anastrozole EP Impurity F<br>Applications 4-Methylbenzenesulfonic Acid Monohydrate (Lisinopril EP Impurity B) is used in the synthesis of resveratrol. Also used in the synthesis of oxane derivatives as antimalarial agents.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Davis, M. et al.: Org. Prep. Proc. Int., 45, 304 (2013); Wang, X. et al.: J. Med. Chem., 56, 2547 (2013);<br></p>

<p>Applications: (3,5-Di-tert-butyl-4-methoxyphenyl)boronic acid (cas# 233584-42-4) is a useful research chemical.<br></p>

<p>Applications N-Acetyl-L-tyrosine is an analogue of L-tyrosine which stimulate the transport of L-Tyr, mainly by the ASC system.<br>References Jara, J. et al.: Melanoma Res., 1, 15 (1991),<br></p>

<p>Applications 2-Bromo-4'-methylpropiophenone (cas# 1451-82-7) is a compound useful in organic synthesis.<br></p>

<p>Applications A well-known, highly active stimulant of cell divisions in plant tissue cultures.<br>References D.S. Letham: Phytochemistry, 12, 2445 (1973)<br></p>

<p>Applications N-Methylcaprolactam is a reagent that is used in the synthesis of 3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone-13C5, which is a chlorinated furanone that accounts for more of the mutagenic activity of drinking water than any other disinfection byproduct.<br></p>

<p>Applications 3-Hydroxy-4-methylaniline<br></p>

<p>Applications Methyl(4-methylnaphthalen-1-ylmethyl)amine is a reagent in the preparation of heterocyclic compounds as enoyl-acyl carrier protein reductase FabI inhibitors and antibacterial agents.<br>References Stuetz, A., et al.: J. Med. Chem., 29, 112 (1986); Berman, J., et al.: PCT Int. Appl., 2004:515512 (2004)<br></p>

<p>Applications 4-methyl-2-(4-(trifluoromethyl)phenyl)thiazole-5-carboxylic acid (cas# 144059-86-9) is a useful research chemical.<br></p>

<p>Applications 4,5-Dihydro-5-methyl-3,4-diphenyl-5-isoxazolol is an intermediate for the preparation of Valdecoxib.<br></p>

<p>M02962 - H-Thr-OH</p>