Amino Acids (AA)

<p>Applications (4-Methylphenyl)-2-pyridinylmethanone is a useful reactant in organic synthesis.<br>References Hu, Zhiyuan, et al.: Org. &amp; Biomol. Chem., 16(31), 5653-5660 (2018);Liao, Yang, et al.: J. of Organometallic Chem., 881, 1-12 (2019)<br></p>

<p>Applications Methyl 5-(Ethylsulfonyl)-2-methoxybenzoate (cas# 62140-67-4) is a useful research chemical.<br></p>

<p>Applications 5-Methoxy-N-methyl-N-(1-methylethyl)-α-oxo-1H-indole-3-acetamide is an intermediate used in the synthesis of 5-Methoxy-N-methyl-N-isopropyl Tryptamine (M271680), which is a psychedelic tryptamine related to N-methyl-N-isopropyltryptamine. 5-Methoxy MiPT potently inhibits the re-uptake of the monoamines serotonin and norepinephrine but does not affect dopamine re-uptake. 5-Methoxy MiPT has no effect on the release of monoamines from rat brain synaptosomes. This product is intended for forensic and research applications.<br>References Katagi, M., et al.: Jpn. J. Forensic Toxicol., 20, 303 (2002), Meatherall, R., et al.: J. Anal. Toxicol., 27, 313 (2003), Wilson, J., et al.: Forensic Sci. Int., 148, 31 (2005), Kamata, T., et al.: Drug Metab. Dispos., 34, 281 (2006),<br></p>

<p>Applications 4-Chloro-4-methyl-1-pentene affects the surface modification of Kevlar stitch threads on mechanical interfacial properties of carbon fiber and bismaleimide stitched composites.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ai, T., et al.: Fuhe Cailiao Xuebao, 24, 34-39 (2007)<br></p>

<p>Applications (2-hydroxy-4-methoxyphenyl)(4-methylphenyl)methanone (cas# 1641-17-4) is a useful research chemical.<br></p>

<p>Applications N-t-Boc-2-bromoethylamine (Technical grade, ~90%) (cas# 39684-80-5) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-Methyl-5-nitrobenzenesulfonamide is a chemical reagent in the synthesis of good inhibitors of cancer-related carbonic anhydrase. Also used in the synthesis of novel deacetylase inhibitors used in anti-tumor therapy.<br>References Moeker, J. et al.: J. Med. Chem., 57, 3522 (2014); Han, L. et al.: Bioorg. Med. Chem., 22, 1529 (2014);<br></p>

<p>Applications 4-Amino-2-methyl-5-pyrimidinemethanesulfonic acid is used in the biosynthesis of Thiamine (T344185) in yeast.<br>References White, R., et al.: Journal of the American Chemical Society, 104, 4934 (1982).<br></p>

<p>Applications 2-Methoxypropene is used in the synthesis of Macrolactin A, a 24-member macrolide typically employed as an antibiotic. Also used in the synthesis of phenylalanine derivatives used as α4β1 and α4β7 receptor antagonists in the treatment of allergic asthma.<br>References Marino, K. et al.: J. Am. Chem. Soc., 12, 1664, (2002); Tilley, J. et al.: Bioorg. Med. Chem. Lett., 23, 1036 (2013);<br></p>

<p>Applications 2-Methoxyethyl 3-oxobutanoate (cas# 22502-03-0) is a useful research chemical.<br></p>

<p>Stability Hygroscopic, Light Sensitive<br></p>

<p>Applications 1-(3-ACETYL-2-HYDROXY-5-METHYL-PHENYL)-ETHANONE (cas# 55108-28-6) is a useful research chemical.<br></p>

<p>Applications 2-(3,4-Diethoxyphenyl)ethanamine is a useful intermediate in the preparation of Drotaverine hydrochloride, an antispasmodic drug arising from papaverine class of biologically active compounds.<br>References Turks, M., et al.: Rigas Tehniskas Universitates Zinatniskie Raksti, Serija 1: Materialzinatne un Lietiska Kimija, 23, 107 (2011)<br></p>

<p>Applications VINYLTRIS(2-METHOXYETHOXY)SILANE (cas# 1067-53-4) is a useful research chemical.<br></p>

<p>Applications Zinc Glycinate is used in the preparation of hydroxy acid complexes used in skin antiaging, acne and skin whitening formulations.<br></p>

<p>Applications 6-Methylquinoline, is a building block used for the synthesis of various pharmaceutical compounds, and biologically active compounds. It can be used for the preparation of pyranobenzopyrone compounds, having anti-norovirus activity.<br>References Pokhrel, L., et al.: bioorg. Med. Chem. Lett., 22, 3480 (2012);<br></p>

<p>Applications 2-Amino-5-methylpyridine (cas# 1603-41-4) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Francotte, P., et al.: Bioorg. Med. Chem., 16, 9948 (2008), Sundaraganesan, N., et al.: J. Mol. Struc., 891, 284 (2008), Caleta, I., et al.: J. Med. Chem., 52, 1744 (2009),<br></p>

<p>Applications 3-Methylindole metabolite.<br>References Skordos, K., et al.: Chem. Res. Toxicol., 11, 741 (1998), Lanza, D., et al.: Drug Metab. Disposition, 29, 950 (2001), Hoenicke, K., et al.: J. Agric. Food Chem., 50, 4303 (2002),<br></p>

<p>Applications δ-Valerolactam-d4 is a labeled analog of δ-Valerolactam (V091440), which is a useful synthetic intermediate. It is an intermediate used to synthesize Cenicriviroc (C256550), an experimental drug candidate for the treatment of HIV infection. It is also a starting material for a new route to hexahydrojulolidines, using intramolecular 1,4-cycloaddition.<br>References Potts, K., et al. J. Org. Chem., 58, 5040 (1993); Klibanov, O., et al.: Curr. Opinion Invest. Drugs, 11, 940 (2010);<br></p>

<p>Applications 1-Methyluracil (cas# 615-77-0) is a compound useful in organic synthesis.<br></p>

<p>Applications 4-Hydroxy-4-methyl-2-pentanone-d12 (CAS# 114253-85-9) is a useful isotopically labeled research compound.<br></p>

<p>Applications 3-Methyl-2-hexanamine HCl Salt is more stable and easier to purify compared to the free base.<br></p>

<p>Applications Intermediate in the production of anti-cancer quinoline derivatives and antibacterial agents<br>References Zhao, H., et al.: Bioorg. Med. Chem. Lett., 12, 3105 (2002),<br></p>

<p>Applications A derivative of imidazole used in the synthesis of heteroxanthine.<br>References Sarasin, J., et al.: Helv. Chim. Acta, 7, 713 (1924),<br></p>

<p>Applications 4-methyl-2-(piperidin-4-yl)pyridine (cas# 1260886-47-2) is a useful research chemical.<br></p>

<p>Applications [2-(1-methyl-1H-pyrazol-3-yl)-1H-benzimidazol-1-yl]acetic acid (cas# 1171565-50-6) is a useful research chemical.<br></p>

<p>Applications 2,2-Dimethoxy-N-methylethanamine is an impurity formed in the synthetic process of Methimazole (M260300), a thiourea antithyroid agent that prevents iodine organification,<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sitar, D.S., et al.: J. Pharmacol. Exp. Ther., 184, 432 (1973), Aboul-Enein, H.Y., et al.: Anal. Profiles Drug Subs., 8, 351 (1979), Cooper, D.S., et al.: N. Engl. J. Med., 311, 1353 (1984), Atterwill, C.K., et al.: Food Chem. Toxicol., 29, 355 (1991),<br></p>

<p>Applications 1-[1-(2-methoxyethyl)piperidin-3-yl]methanamine (cas# 936940-49-7) is a useful research chemical.<br></p>

<p>Stability Moisture Sensitive<br>Applications N-Methyl-1H-imidazole-1-carboxamide is a useful Methyl Isocyanate (MIC) substitute.<br></p>

<p>Stability Hygroscopic<br>Applications 4-Chloro-2-methylaniline Hydrochloride (cas# 3165-93-3) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Phytosiderophores are produced in higher plants as iron chelating amino acids that promote uptake of iron from soil.<br>References Klair, S., et al.: J. Plant Nutr., 19, 1295 (1996),<br></p>

<p>Applications 2-Methoxybenzoic Acid is used in the preparation of benzohydroxamic acids as potent and selective anti-hepatitis C virus (HCV) agents.<br>References Kozlov, M.V., et al.: Bioorg. Med. Chem. Lett., 23, 5936 (2013)<br></p>

<p>Applications N-Acetyl-L-tyrosine is an analogue of L-tyrosine which stimulate the transport of L-Tyr, mainly by the ASC system.<br>References Jara, J. et al.: Melanoma Res., 1, 15 (1991),<br></p>

<p>Applications L-Allo-isoleucine-d10 is a derivative compound of L-allo-isoleucine (A548200), which has been suggested to induce epithelial β-defensin expression. In addition, L-allo-isoleucine is utilized in the biosynthesis pathway for coronamic acid.<br>References Fehlbaum, P., et al.: Proc. Natl. Acad. Sci. USA 97, 12723 (2000); Parry, R. J., et al.: J. Am. Chem. Soc. 113, 1849 (1991)<br></p>

<p>Applications 3-[4-(2-methoxyphenyl)piperazin-1-yl]propan-1-amine (cas# 20529-23-1) is a useful research chemical.<br></p>

<p>Impurity Betahistine EP Impurity C (Free Base)<br>Applications N-Methyl-N,N-bis(2-pyridylethyl)amine is used as a reagent in the preparation of copper pyridylmethylethylenediamine dicyanamido polymeric complexes.<br>References Mautner, F.A. et al.: Inorg. Chim. Acta, 362, 4073 (2009);<br></p>

<p>Applications 5-Amino-2-methylbenzotrifluoride is used to prepare azoles as inhibitors of VEGF receptors 1 and 2 with high intestinal permeability. It can also be used to prepare curcumin analogs conjugated with antiandrogens.<br>References Kiselyov, A., et al.: Bioorg. Med. Chem. Lett., 17, 1369 (2007); Shi, Q., et al.: Bioorg. Med. Chem., 20, 4020 (2012)<br></p>

<p>Applications Cyclic propano guanine adduct DNA acetaldehyde histone.<br>References Nath, R., et al.: Cancer Res., 58, 581 (1998), Wang, M., et al.: Chem. Res., 13, 1065 (2000), Terashima, I., et al.: Biochemistry, 40, 4106 (2001), Yokoyama, A., et al.: Carcinogenesis, 23, 1851 (2002),<br></p>

<p>Applications N-Methylcaprolactam is a reagent that is used in the synthesis of 3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone-13C5, which is a chlorinated furanone that accounts for more of the mutagenic activity of drinking water than any other disinfection byproduct.<br></p>

<p>Applications 5-Methoxy-2-methylaniline (cas# 50868-72-9) is a useful research chemical.<br></p>

<p>Stability Hygroscopic<br>Applications Genetic incorporation of a metal-ion chelating amino acid into proteins as a biophysical probe.<br>References McRee, D., et al.: J. Struct. Biol., 125, 156 (1999), Wang, L., et al.: Science, 292, 498 (2001), Ioerger, T., et al.: Methods Enzymol., 374, 244 (2003),<br></p>

<p>Applications N-Methyl-3,3-diphenylpropylamine is an intermediate for the synthesis of SNRI-NMDA antagonist and neuroprotectants.<br>References Olney, J. et al.: Sci., 244, 1360 (1989); Williams, W., et al.: Mol. Pharmacol. 44, 851 (1993);<br></p>

<p>Applications N,O-Dibenzoyl-DL-tyrosyl-N',N'-dipropylamide is a metabolite of the antispasmodic agent Tiropramide (T446900). Tiropramide impurity B.<br>References Janssen, et al.: J. Pharm. Pharmacol., 9, 381 (1956), Bertaccini, et al.: Br. J. Pharmac., 34, 310 (1968),<br></p>

<p>Stability Hygroscopic<br>Applications A labelled metabolite of Methyl isocyanate.<br>References Slatter, J. G., et al.: Chem. Res. Toxicol., 4, 157 (1991),<br></p>

<p>Stability Hygroscopic<br>Applications Decanoyl-L-carnitine-d3 Chloride is the isotope labelled analog of Decanoyl-L-carnitine Chloride (D212580); a metabolite of L-Carnitine (C184110) which is an essential cofactor of fatty acid metabolism. Also required for the transport of fatty acids through the inner mitochondrial membrane.<br>References Mitchell, M.E., et al.: Am. J. Clin. Nutr., 31, 293 (1978); Lango, R., et al.: Cardiovasc. Res., 51, 21 (2001); Vaz, F.M., et al.: Biochem. J., et al.: 361, 417 (2002); Karlic, H., et al.: Nutrition, 20, 709 (2004)<br></p>

<p>Applications 2-Methyl-4-oxo-4-phenylbutyric Acid is a chemical reagent used in the synthesis of various pharmaceutically active compounds. Used in the synthesis of Minozac, a suppressor of brain proinflammatory cytokine up-regulation.<br>References Hu, W. et al.: Bioog. Med. Chem. Lett., 17, 414 (2007); Qabaja, G. ET AL.: J. ORG. CHEM., 80, 133 (2015);<br></p>

<p>Applications 2-Methyldibenzothiophene, is an alkyldibenzothiophene present in crude oil. Research concerning the biodegradation of Dibenzothiophene by different types of bacteria is a currently being carried out, as these bacteria have the ability to breakdown other harmful PAH’s as well. This may be used in removing spilled oil from marine and terrestrial environments.<br>References Boberg, F., et al.: Erdoel &amp; Kohle, Erdgas, Petrochemie, 47, 187 (1994); Tanaka, Y., et al.: Applied Microbiology and Biotech., 59 (2), 325 (2002); Prince, R., Spill Sci. Tech. Bulletin, 8 (2), 145 (2003);<br></p>