Amino Acids (AA)

<p>Please enquire for more information about trans-3-Hydroxy-L-proline including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about PAR-3 (1-6) (human) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>LL-37 TFA is a reagent, complex compound and useful intermediate for the fine chemical and pharmaceutical industries. It is also an important building block for the synthesis of other chemicals. LL-37 TFA has CAS No. 71428-08-9, which is a speciality chemical that can be used in research as well as in many different reactions. The versatility of this compound makes it a very useful building block for the synthesis of other chemicals.</p>

<p>Ethyl 2-hydroxy-5-methoxybenzoate (EHMB) is a phenolic compound that belongs to the group of salicylic acid. It is a natural product present in crucifers such as cabbage, broccoli, and cauliflower. EHMB has been shown to induce apoptosis in human leukemia cells through the inhibition of DNA methylation. The results showed that EHMB induces apoptosis in human leukemia cells by targeting the epigenetic regulator protein MLL1, which inhibits DNA methyltransferase 1 activity and leads to decreased levels of 5mC. EHMB also induces apoptosis in lung cancer cells by inhibiting cell proliferation and inducing cell death through the inhibition of GTPase activity, which leads to decreased levels of cyclin D1 and increased levels of p27. EHMB also regulates stem cell function by modulating gene expression; it has been shown that this compound can promote stem cell-like properties in mouse embryonic fibrobl</p>

<p>N-Methyl mesoporphyrin IX is a molecule that inhibits the activity of enzymes such as carboxylesterases, proteases, and aminopeptidases. It binds to the active site of these enzymes and blocks the enzyme's activity. N-Methyl mesoporphyrin IX has been shown to inhibit cancer cells in humans and can be used as an adjunct treatment for cancer. This drug also has anti-inflammatory properties due to its ability to inhibit prostaglandins synthesis. N-Methyl mesoporphyrin IX has been shown to have an effect on plant physiology by inhibiting plant growth and photosynthesis. N-Methyl mesoporphyrin IX is also able to enhance hybridization reactions between dsDNA duplexes, which may be useful in research involving DNA sequencing or gene mapping.</p>

<p>Fmoc-Cys(Dpm)-OH is a chemical that belongs to the group of reaction components. It is a high quality reagent for research and development and can be used as a building block in the synthesis of other fine chemicals. Fmoc-Cys(Dpm)-OH is also an intermediate for the synthesis of complex compounds such as peptides, proteins, and antibiotics. This compound has a broad range of applications in biomedicine, organic chemistry, and pharmaceuticals.</p>

<p>Please enquire for more information about N3-Phe-OH·CHA including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4-Methoxy 17β-estradiol is a synthetic estrogen that is used as a pharmaceutical drug in the treatment of menopausal symptoms and to prevent osteoporosis. It can be taken orally or administered by injection. 4-Methoxy 17β-estradiol has been found to have interactive effects with other drugs, such as fatty acids and catechol-o-methyltransferase (COMT). It also has an effect on body mass index in vivo, which can lead to cancerous cell proliferation. The matrix effect of 4-methoxy 17β-estradiol on tissues depends on the hydrogen bonds it forms with amino acids in the protein matrix. The hydrogen bonds are different for each tissue type and this may contribute to the differences in carcinogenic potential between tissues. This drug is not active against MCF-7 human breast cancer cells, but does inhibit growth of MDA MB 231 human breast cancer cells.</p>

<p>2-Chloro-5-methyl-1,4-benzoquinone is a heterocyclic organic compound with the molecular formula CHClO. It is a crystalline solid that occurs in two forms, the alpha and beta forms. The alpha form consists of an asymmetric unit containing two fused rings, one with five carbon atoms and another with six. The beta form has a similar structure but the ring with six carbon atoms is replaced by a carbon atom substituted for sulfur. 2-Chloro-5-methyl-1,4-benzoquinone can be used as an emulsifying agent or to produce benzoquinone by oxidation of hydroquinone or by electrochemical reduction of methylene blue. This chemical also has been used as an electron acceptor in supramolecular chemistry studies.</p>

<p>1,10-Phenanthroline monohydrate is a metal chelate that binds to DNA by hydrogen bonds. It has been shown to have an intramolecular hydrogen and a linear calibration curve with a coefficient of determination (r2) of 0.998. The rate constant for the reaction of 1,10-phenanthroline monohydrate with DNA is 5.00 x 10 M-1 s-1 at 25°C in water and pH 7.4 buffer. The coordination geometry for 1,10-phenanthroline monohydrate is octahedral with the axial ligands occupying the equatorial positions and the equatorial ligands occupying the axial positions. This compound has been shown to be active against HL-60 cells, which causes cancerous transformations in vitro. Fluorescence spectrometry data shows that 1,10-phenanthroline monohydrate can bind to DNA in vitro but not in vivo.</p>

<p>2-fluoro-5-methoxybenzaldehyde is an asymmetric synthesis that has been shown to inhibit the growth of cancer cells by inhibiting a protein called MT2. 2-Fluoro-5-methoxybenzaldehyde is a nucleophilic compound and reacts with the electrophilic carbon in the enolate to form a sulfoxide, which can be hydrolyzed by acid. This reaction inhibits cancer cell growth as it prevents cellular metabolism and amino acid biosynthesis.</p>

<p>Please enquire for more information about Boc-S-acetamidomethyl-L-cysteine 4-nitrophenyl ester including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 4-(4-Chlorophenyl)-2-(3-methyl-5-oxo-1-phenyl(2-pyrazolin-4-yl))-4-oxobutanoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Fmoc-Asn(Trt)-OH is a pegylated molecule synthesized by attaching a polyethylene glycol (PEG) to the terminal amino acids. It has been shown that Fmoc-Asn(Trt)-OH inhibits peptide synthesis by inhibiting the formation of an enzyme-substrate complex. This inhibition prevents the transfer of an amino acid from one protein chain to another, preventing the formation of a new chain and subsequent polymerization. Fmoc-Asn(Trt)-OH also has an inhibitory effect on polypeptide synthesis. The molecular weight of this compound is about 535 Daltons.</p>

<p>Please enquire for more information about Fmoc-O-allyl-L-tyrosine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>O-Phospho-DL-serine is a nonprotein amino acid that is synthesized in plants and microorganisms. It is an intermediate in the metabolism of phosphoserine, which can be converted to phosphoserine by the enzyme phosphoserine phosphatase. O-Phospho-DL-serine has been shown to have anti-cancer properties, as it inhibits the growth of various human cancer cell lines by dephosphorylating and inhibiting protein kinases. O-Phospho-DL-serine also has a role in the activation of response elements and cytokines, especially in the presence of growth factors such as fibroblast growth factor β1 (FGFβ1).</p>

<p>1-Boc-1,8-diaminooctane is a polymerase that is used in the synthesis of DNA. It has been shown to be able to cleave supercoiled DNA and bind to acidic surfaces. This compound is fluorescent and can form covalent adducts with nucleic acids. 1-Boc-1,8-diaminooctane also has a piperidine group, which can act as a linker for other molecules such as anthracene. 1-Boc-1,8-diaminooctane is a neutral pH compound that reacts well with biomolecules.</p>

<p>4-Amino-2-methylbenzoic acid ethyl ester is a versatile building block that can be used in the synthesis of complex compounds. It has been shown to have a number of useful applications, such as in the synthesis of pharmaceuticals, research chemicals, and speciality chemicals. 4-Amino-2-methylbenzoic acid ethyl ester is also an important reagent for the production of high quality pharmaceuticals and intermediates. This chemical is also a useful scaffold for organic reactions.</p>

<p>Z-Gly-Met-OH is a buffer that can be used to create an acidic solution. It is often used in liquid chromatography and peptide synthesis. Z-Gly-Met-OH has been shown to have potential use as an enzyme inhibitor, specifically for proteases and peptidases. The hydrolyzed form of Z-Gly-Met-OH has been shown to bind zinc ions and could be used in the treatment of metal ion poisoning.</p>

<p>N-Cbz-L-valinyl-ganciclovir is a prodrug of ganciclovir. It is synthesized by reacting the amino acid L-valine with the nucleoside analogue ganciclovir in an organic solvent. The product can be purified by filtration and crystallizing using hydrochloric acid and then recrystallized from a mixture of chloroform and trimethylsulfonium chloride. N-Cbz-L-valinyl-ganciclovir is more stable than ganciclovir, which has been shown to be degraded by urea hydrolase. This product can also be recycled after it has been used.</p>

<p>L-Aspartic acid b-methyl ester hydrochloride is a high quality, versatile building block that can be used as a reaction component in the synthesis of complex compounds. L-Aspartic acid b-methyl ester hydrochloride is a useful scaffold for the preparation of novel fine chemicals and research chemicals with potential uses as pharmaceuticals, pesticides, and agricultural chemicals. It can also be used as an intermediate in the preparation of some natural products or industrial chemicals. L-Aspartic acid b-methyl ester hydrochloride has a CAS number of 16856-13-6.</p>

<p>Inhibitor of cathepsins</p>

<p>Useful chiral building block</p>

<p>2-Amino-N-methylbenzamide is a benzodiazepine receptor antagonist that has been shown to inhibit the proliferation of cancer cells in vitro. 2-Amino-N-methylbenzamide binds to the benzodiazepine receptor, which is found in cell nuclei and is involved in controlling the process of cell division. Benzodiazepines are a class of drugs that work by increasing the activity of GABA, which reduces neuronal excitability. 2-Amino-N-methylbenzamide prevents this activity by binding to the benzodiazepine receptor, preventing GABA from binding to its receptors and thereby inhibiting neuronal excitability. This drug has also been shown to inhibit cancer growth through an anthranilic acid derivative, methyl anthranilate. Methyl anthranilate inhibits DNA synthesis and induces apoptosis in cancer cells, leading to cell death.</p>

<p>3-Glycidoxypropyl methyldimethoxysilane (3-GPMDMS) is a compound that belongs to the group of organosilicon compounds. It is an organic solvent that has been used for the activation energy of ring-opening reactions. 3-GPMDMS is also suitable for immobilizing polysaccharides, proteins, and enzymes on surfaces or in polymer matrices. 3-GPMDMS has been used to produce polymers with high molecular weight and a wide range of molecular weights by polymerization. 3-GPMDMS can be synthesized by reacting glycidoxypropyltrimethoxysilane with methanol in the presence of hydrochloric acid. The chemical structure includes methoxy groups connected to silicon atoms via methylphenyl groups. 3-GPMDMS has been shown to exhibit excellent magnetic resonance properties and be a potential candidate for use as nanomaterials. It</p>

<p>Intermediate in the synthesis of vildagliptin</p>

<p>N-Acetyl-L-aspartyl-L-glutamic acid is an amino acid that is used as a substrate in the biochemical assay for glutamate. It is also used to measure brain functions. NAAG is a low potency agonist of the NMDA receptor, which may contribute to neuronal death. NAAG is used as a model system to study bowel disease and eosinophil cationic protein. It has been shown to be effective in vitro against cancer cells and fungi. The structural analysis of NAAG has revealed that it contains an acidic group on its side chain, which can be detected with a pH indicator such as phenol red or bromocresol purple.</p>

<p>L-threo-Phenylserine is a naturally occurring amino acid that is synthesized in the human body. It can be found in the brain and muscles, where it is used for protein synthesis. L-threo-phenylserine has been shown to be an effective oxygen nucleophile and can catalyze the hydrolysis of hydrogen fluoride. This compound has also been shown to have biological activity in vitro as well as structural properties that are useful for conformational analysis and structural biology research. L-threo-phenylserine may also have potential medical applications, such as its use as a treatment for mental disorders and epilepsy.</p>

<p>Please enquire for more information about 3-Methyl-5-isoxazoleacetic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Head activator (7-11) acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Copper glycine is a complex enzyme that contains molybdenum, nitrogen and fatty acid. It is a metal chelate that binds to copper ions and prevents the oxidation of fatty acids. The complex has been shown to inhibit the activity of many different enzymes, including those from group P2 (e.g., pyruvate formate lyase) and nutrient solutions. Copper glycine has also been implicated in antimicrobial peptide synthesis.</p>

<p>2-Ethoxy-4-methoxybenzaldehyde is a volatile compound that has been shown to have medicinal properties. It is used to analyze the presence of alcohols and aldehydes in various products. The sensitivity of this compound was optimized by using an analytical method that involved solid phase microextraction (SPME) followed by gas chromatography (GC). The carcinogenicity of this compound was determined by exposing it to rats in a 2 year study, which showed no evidence of carcinogenicity. This compound can also be used as a phenolic or microextraction reagent for the headspace analysis of volatile compounds.</p>

<p>Acetyl-L-tyrosine amide is an analog of L-tyrosine that is used as an active substance in the field of uv absorption. Acetyl-L-tyrosine amide reacts with sodium hydroxide to form a soluble salt, which has been shown to have binding constants that are comparable to those of human serum. This compound also has fluorescence properties and can be used for the determination of neutral pH. The reaction products formed between acetyl-L-tyrosine amide and sodium hydroxide are hydrolyzed by acids and yield a molecule with rotameric properties. These rotameric properties can be modeled using a protein model without affecting the stability or function of the protein.</p>

<p>Please enquire for more information about 3-((4-methylphenyl)amino)-2-phenylinden-1-one including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 1-Benzyl-4-(2-bromo-2-methylpropanoyl)piperazine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Fmoc-L-homophenylalanine is a homophenylalanine analogue that inhibits the intracellular Ca2+ levels by binding to the ester linkages in the phospholipid membrane. This inhibits viral replication and has been shown to inhibit the replication of coronaviruses, such as SARS-CoV, and respiratory syncytial virus (RSV). Fmoc-L-homophenylalanine also inhibits lung fibroblasts from producing cytokines and chemokines, which may be due to its ability to inhibit methyl ketones, an important precursor for proinflammatory compounds. It also inhibits P. aeruginosa growth by preventing bacterial cells from synthesizing proteins and DNA.</p>

<p>Fmoc-beta-Ala-4-amino-D-Phe(Boc)-OH is a fine chemical that can be used as a building block in research, as a reagent for chemical synthesis, or as a speciality chemical. It is also a versatile building block that can be used to create other compounds. Fmoc-beta-Ala-4-amino-D-Phe(Boc)-OH is an intermediate compound and scaffold. This compound has been shown to react with ethyl chloroformate to yield the corresponding beta amino ester.</p>

<p>Boc-Asp(OBzl)-Pro-Arg-AMC·HCl is a high quality, reagent, complex compound and useful intermediate. It is a fine chemical with the CAS Number 201849-39-0 that is used in research and development. Boc-Asp(OBzl)-Pro-Arg-AMC·HCl is also a versatile building block that can be used in reactions for the synthesis of other compounds.</p>

<p>Cypermethrin is an insecticide that belongs to the family of chemical pesticides. It is used in agriculture and in public health to control malaria-transmitting mosquitoes, head lice, and scabies mites. Cypermethrin disrupts the insect nervous system by inhibiting the function of synapses between nerves, resulting in paralysis and death. The compound also affects signal pathways that regulate locomotor activity and enzyme activities. Cypermethrin has been shown to have a high resistance to degradation by glycol ethers such as ethylene glycol monomethyl ether acetate (EGMEA). It has an optimum concentration of 0.01 ppm for mosquito control and 0.1 ppm for lice control. The analytical method involves liquid chromatography with sodium citrate as an ion-pairing agent and a linear calibration curve using a standard curve generated from known concentrations of cypermethrin.</p>

<p>Fmoc-O-tert-butyl-D-threonine is an ion pair that is synthesized using an asymmetric synthesis process. The molecule has been shown to have antiproliferative effects in animals and humans and can inhibit neutrophil function. This synthetic compound has a glycan (a carbohydrate) attached to the side chain, which may be important for its biological activity. Fmoc-O-tert-butyl-D-threonine was synthesized on a solid phase and functional groups were introduced as part of the synthesis process. This molecule also has an inhibitory effect on ulceration in animals.</p>

<p>Tos-Gly-Pro-Lys-pNA acetate is a peptide that has been shown to have inhibitory effects on serine proteases, such as fibrinogen. Tos-Gly-Pro-Lys-pNA acetate binds to the active site of serine proteases, which inhibits their activity and prevents them from cleaving fibrinogen. The rate of reaction is dependent on the concentration of enzyme inhibitors. For example, at low concentrations, the enzyme inhibitor will bind to only one or two sites on the serine protease, while at high concentrations it may bind to many sites. This molecule has been shown to be a potent inhibitor of human immunodeficiency virus (HIV) protease and is currently being studied for its use as a potential antiviral agent.</p>

<p>2-Methyl-1,3-cyclohexanedione is an organic compound that has been used in the synthesis of a variety of drugs. The functional theory for this type of reaction is based on the conformational properties and steric interactions of the reactants. This compound can react with alkyl halides to form ethers or esters by using a lipase or boronic ester as a catalyst. 2-Methyl-1,3-cyclohexanedione has also been used in asymmetric syntheses and radiation damage studies. It is stable under acidic conditions and its carbonyl group can be replaced with a supercritical carbon dioxide group to make it more chemically stable.</p>

<p>N-(2-Fluorophenyl)-N-[4-(4-methyl-1,3-thiazol-2-yl)-1-(2-thiophen-3-ylethyl)piperidin-4-yl]propanamide is a drug that is used for the treatment of cancer. This drug is hydrophobic and has a molecular weight of 455. It has been shown to be effective in treating cancer cells by binding to the cell membrane and inhibiting the proliferation of these cells. N-(2-Fluorophenyl)-N-[4-(4-methyl-1,3-thiazol-2-yl)-1-(2-thiophen-3-ylethyl)piperidin]-4-- yl]propanamide also inhibits tumor growth by reducing extracellular matrix production and inducing apoptosis in cancer cells. This drug has a fluorescent property and can be detected with an optical microscope at a</p>

<p>The Val-Cit-PAB linker is an activated peptide linker that is cleaved by cathepsin B. It enables the selective intracellular release of attached drugs in ADC applications.</p>

<p>Methyl 3-methyl-2-nitrobenzoate is a chiral, catalytic, and magnetic additive. It is used in the production of alkyl chlorides, cinnolines, and cyclic compounds. Methyl 3-methyl-2-nitrobenzoate can be used as a diagnostic for chloride ions or chlorine gas in water. It also has an important application in wastewater treatment by removing organics from wastewater effluent. Methyl 3-methyl-2-nitrobenzoate can be synthesized from allylic oxidation of methyl benzoate with sodium hypochlorite in the presence of copper sulfate catalyst. The reaction proceeds through an addition–elimination mechanism to produce the desired product and copper(II) chloride as a byproduct. The process occurs on a mesoporous material to increase surface area for the reaction to proceed more quickly and efficiently.</p>

<p>Please enquire for more information about 2-Hydroxy-5-iodo-3-methoxybenzaldehyde including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Alpha-methylhydrocinnamic acid (AMHA) is a synthetic enantiomer of 2-phenylbutyric acid, which has been shown to inhibit the growth of k562 cells. It is also a substrate for fatty acid synthase and may play an important role in fatty acid metabolism. AMHA has been shown to inhibit the production of reactive oxygen species by phagocytic cells exposed to ionizing radiation, which may be due to its ability to scavenge hydroxyl radicals. The effect of AMHA on hematopoietic cells, including neutrophils and bone marrow cells, has not yet been determined.</p>

<p>4-Borono-L-phenylalanine is a boron-containing compound that has been used to study the biological effects of radiation. 4-Borono-L-phenylalanine is an analytical tool for measuring neutron scattering and other physical properties. It has also been used as a biochemical probe in studies of DNA duplexes. 4-Borono-L-phenylalanine is toxic to cells, inhibiting protein synthesis, and it can induce apoptosis in tumor cells. In experimental models, 4-borono-L phenylalanine can be administered orally or intravenously and has shown acute toxicity in animals at doses of up to 1000 mg/kg body weight.</p>

<p>6-Fluoro-5-Methyl-2-[(5-Methyl-1H-Imidazol-4-Yl)Methyl]-2,3,4,5-Tetrahydro-1H-Pyrido[4,3-b]Indol-1-One is a drug that belongs to the class of fatty acid esters. It has been shown to be effective in clinical trials for the treatment of symptoms of dry eye syndrome. 6FMETI has a low safety profile and does not cause any adverse effects in humans. The drug can be administered by intravenous injection or oral administration and has a long elimination half life of 36 hours. 6FMETI is metabolized by hydrolysis to its active form, 5FMTI, which is then conjugated with glucuronic acid or methyl glutaryl coenzyme A to form an inactive metabolite. This drug also has good pharmacokinetic properties</p>

<p>N-Nitroso-N-methyl-4-aminobutyric acid (NMBA) is a solid with a low melting point which has been identified as a potentially carcinogenic component of both tobacco and tobacco smoke. NMBA is also one of a number of nitrosamine impurities which have been found to be present in angiotensin II receptor blocker (ARB) drugs used to treat high blood pressure.</p>