Amino Acids (AA)

Applications (2R,4S)-rel-4-Methyl-1,2-piperidinedicarboxylic Acid 1-(1,1-Dimethylethyl) Ester has been used in the preparation of homoproline (H605000), a GABA-uptake inhibitor derived from proline
References Dann, A., et al.: Nature, 186, 1051 (1960); Passreiter, C., et al.: Planta Med., 58, 556 (1992); Roeder, E., et al.: Pharmazie, 48, 953 (1993); Wernery, U., et al.: Fitoterapia, 68, 278 (1997)

Applications Intermediate for the synthesis of glucuronide conjugates of trans-Resveratrol
References Learmonth, D.A., et al.: Bioconjug. Chem., 14, 262 (2003),

Applications Used for the preparation of imidazo[1,2-a]pyridines, imidazo[1,2-a]pyrazines, imidazo[1,2-c]pyrimidines, and imidazo[1,2-d]triazines as JNK and ERK kinase inhibitors.
References Lawrence, D., et al.: J. Med. Chem., 44, 594 (2001), Urquiola, C., et al.: Bioorg. Med. Chem., 17, 1623 (2009),

Applications 3-Methoxy-3-methylbutyl Acetate (cas# 103429-90-9) is a useful research chemical.

Applications 5-Hydroxy-1-(3-methoxy-4-((tetrahydro-2H-pyran-2-yl)oxy)phenyl)decan-3-one is an intermediate used in the synthesis of [6]-Shogaol (S357800), which is an aromatic constituent of ginger and the chain-dehydroxylated analog of [6]-Gingerol. [6]-Shogaol has activity very similar to [6]-Gingerol and produced an inhibition of spontaneous motor activity, antipyretic and analgesic effects, and prolonged hexobarbital-induced sleeping time. [6]-Shogaol also has potent antitussive activity and affected the cortical EEG.
References Suekawa, M. et al.: J. Pharm-Dyn., 7, 836 (1984); Yoshikawa, M. et al.: Chem. Pharmac. Bull., 40, 2239 (1992);

Applications (4-Hydroxy-3-methoxyphenyl)acetic-2,2-d2 Acid (CAS# 53587-33-0) is a useful isotopically labeled research compound.

Applications 2-(1-Cyano-1-methylethyl)azocarboxamide, cna be used in the synthesis of azobenzene side chain polymers derived from the bifunctional fumaric acid and itaconic acid.
References Kim, s. et al.: Polymer, Vol 55. P: 871-877 (2014);

Applications Methyl 3-Hydroxy-4-methylpentanoate is an intermediate in synthesizing 3-Hydroxy-4-methylpentanoic Acid (H947700), which is isolated from Turkish tobacco leaves. It can be used to prepare 1,3-Polyol arrays via stereoselective rearrangement.
References Fukuzumi, T., et al.: Agri. Biol. Chem., 29, 967 (1965); Zhang, Y., et al.: Tetrahedron, 59, 8979 (2003)

Impurity Ranitidine EP Impurity K
Applications N-Methyl-1-(methylthio)-2-nitroethenamine (Ranitidine EP Impurity K) is an intermediate in the preparation of Ranitidine and Nizatidine.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Beaulieu, N., et al.: J. Pharm. Sci., 77, 889 (1988), Buchholz, M., et al.: J. Med. Chem., 52, 7069 (2009),

Applications 1-Boc-hexahydro-1,4-diazepine is a diazepine derivative used in the preparation of pharmaceutical compounds such as histamine H3-receptor antagonists and dipeptidyl peptidase IV (DPP-IV) inhibitors.
References Curtis, M.P. et al.: Arch. Pharm., 337, 219 (2004); Ahn, J. et al.: Bioorg. Med. Chem. Lett., 18, 6525 (2008);

Applications N-Boc-6-hydroxyhexylamine (cas# 75937-12-1) is a compound useful in organic synthesis.

Applications (2-METHYLAMINO-5-NITRO-PHENYL)-PHENYL-METHANONE (cas# 4958-56-9) is a useful research chemical.

Applications (±)-1-Bromo-2-ethyl-3-methyl-d3-butane-3,4,4,4-d4 (CAS# 1219805-84-1) is a useful isotopically labeled research compound.

Applications 6-methyl-2-oxo-4-[(5,6,7,8-tetrahydronaphthalen-2-yl)amino]-1,2-dihydropyridine-3-carboxylic acid (cas# 1239521-17-5) is a useful research chemical.

Applications N-Methoxy-N-methylbenzamide is used to prepare orally bioavailable tetrasubstituted imidazoles as inhibitors of p38 mitogen-activated protein kinase. It is used to synthesize benzofuran and benzothiophene biphenyls as inhibitors of protein tyrosine phosphatase 1B with antihyperglycemic properties.
References Liverton, N., et al.: J. Med. Chem., 42, 2180 (1999); Malamas, M., et al.: J. Med. Chem., 43, 1293 (2000)

Stability Hygroscopic
Applications Isotope labelled 1,6-Anhydro-β-D-glucopyranose (A648100), an compound that have been proven to be a valuable synthon for the preparation of various biologically important and structurally diverse products (e.g. rifamycin S, indanomycin, thromboxane B2, (+)-biotin, tetrodotoxin, quinone, and macrolide antibiotics) as well as for modified sugars.
References Fraser-Reid, B., et al. J. Am. Chem. Soc. 106, 731 (1984); Edwards, M.P., et al. J. Org. Chem. 49, 3503 (1984); Kelly, A.G., and Roberts, J.S. J. Chem. Soc., Chem. Commun. 228, (1980); Ogawa, T., et al. Carbohydr. Res. 57, C31 (1977); Isobe, M., et al. Tetrahedron Lett. 28, 6485 (1987);

Applications 5-Bromo-2-iodo-3-methoxypyridine

Applications 5-Bromo-1-[2-Fluoro-6-(trifluoromethyl)benzyl]-6-methylpyrimidine-2,4(1H,3H)-dione is an intermediate in the synthesis of Elagolix, a gonadotropin-releasing hormone antagonist (GnRH) used in the treatment of endometriosis.
References Tukun, F. et al.: Molecules, 22, 12 (2017);

Applications 2-Methoxybenzoic Acid is used in the preparation of benzohydroxamic acids as potent and selective anti-hepatitis C virus (HCV) agents.
References Kozlov, M.V., et al.: Bioorg. Med. Chem. Lett., 23, 5936 (2013)

Applications 2-Chloro-4-fluoro-3-methylbenzonitrile is a reagent used in the synthesis of a novel and potent nonsteroidal androgen receptor modulator (SARM) with partial agonist activity relative to the natural androgen testosterone.
References Schlienger, N., et al.: J. Med. Chem., 52, 7186-7191 (2009)

Applications 5-Methyl-2(1H)-pyridinone-d6 is a reagent used in the preparation of substituted N-aryl pyridinones as fibrotic inhibitors.

Applications N-METHYL-L-PHENYLALANINE (cas# 2566-30-5) is a useful research chemical.

Applications 4-Hydroxy-6-methoxyquinoline-2-carboxylic Acid (cas# 91092-95-4) is a useful research chemical.

Applications L-threo-Phenylserine is a valuable chiral synthon.

Applications 4-Chloro-7-methoxy-2-methylquinoline (cas# 75896-68-3) is a useful reagent for preparing multi-substituted 4-anilinoquin(az)olines that have antiviral activity.
References Saul, S., et al.: Bioorg. Med. Chem. Lett., 30, 127284 (2020)

Applications S)-β-Phenylalanine is a key building block used as an intermediate in the synthesis of pharmaceuticals.
References Hisashi, K., et al.: Biosci, Biotechnol,Biochem, 70, 99 (2006);