Amino Acids (AA)

Applications 2-Bromo-6-methoxy-1,3-benzothiazole

Applications Methyl 2-chloro-3-methylbenzoate

Applications α-Methylstyrene-d5 Oxide is labelled α-Methylstyrene Oxide (M325390) which is structurally similar to rac Styrene Oxide (S687795), a major (toxic) metabolite of Styrene (S687790), catalyzed by epoxide hydrolase.
References Shen, S. et al.: Drug Metab. Disp., 38, 1934 (2010); Carlson, G.P. et al.: J. Toxicol. Env. Health, 73, 1689 (2010)

Applications Methyl 4-Methylpyrrole-2-carboxylate is a useful reagent for preparation of (E)-3-(2-(N-phenylcarbamoyl)vinyl)pyrrole-2-carboxylic acid derivatives, a novel class of glycine site antagonists.
References Balsamini, C., et al.: J. Med. Chem., 41, 808 (1998);

Applications N,N-Dimethyl-4-(4-methylphenyl)-4-oxo-2-butenamide is a starting material and useful building block in chemical synthesis.

Applications N-(3-Methoxypropyl) DL-Z-Phenylalaninamide

Applications 7-Methyl-8-nitroquinoline (cas# 7471-63-8) is a useful research chemical.

Applications L-Glutamic Acid Dimethyl Ester-13C5 Hydrochloride is an intermediate used in the synthesis of Folic Acid-13C5 (F680303), which is vitamin needed to synthesize DNA, conduct DNA repair and methylate DNA, it also acts as a cofactor in biological reactions involving folate.
References Xu, L., et al.: Mol. Pharm., 7, 1311 (2010), Everette, J., et al.: J. Agric. Food Chem., 58, 8139 (2010), Alshatwi, A., et al.: Food, Chem., Toxicol., 48, 1881 (2010), McKay, D., et al.: Nut. J., 9 (2010),

Applications 1,5-Diphenyl-3-methylpyrazole (cas# 3729-90-6) is a useful research chemical.

Applications Important building block for the synthesis of peptides containing DAP residues, e.g. bleomycins, edeines, tuberactinomycins.
References Thuring, J., et al.: Biochem., 41, 2002 (2002), Hausch, F., et al.: Chem. Biol., 10, 225 (2003), Palucki, B., et al.: Bioorg. Med. Chem. Lett.,15, 1993 (2005),

Applications 3-Methoxyphenylboronic Acid is a phenylboronic acid used to investigate boron function in plants.
References Baldwin, T., et al.: Plant Physiol., 103, 115 (1993), Andeme-Onzighi, C., et al.: Planta, 215, 949 (2002), Brown, P., et al.: Plant Biol. 4, 205 (2005),

Applications 1-Chloro-3-methyl-2-butene is a reactive allylic chloride that is used as an alkylating agent in synthetic chemistry. 1-Chloro-3-methyl-2-butene is also used as a reagent to synthesize Hyperforin, an antibiotic originating from St. John’s wort that has the ability to inhibit growth of tumour cells.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Hatch, L. & Gerhardt, L.: J. Am. Chem. Soc., 71, 1679 (1949); Lee, M., et al.: Org. Lett., 6, 1241 (2004); Reitsema, R. & Hunter, J.: J. Am. Chem. Soc., 71, 1680 (1949); Schempp, C., et al.: Oncogene, 21, 1242 (2002); Sparling, B., et al.: J. Am. Chem. Soc., 135, 644 (2013)

Applications Di-tert-butyldimethylsilyl Ethers 2-Linoleoyl-rac-glycerol is an intermediate in the synthesis of 2-Linoleoyl-rac-glycerol (L467960), which is a fatty acid monoglycerides in vegetable oils with medium unsaturation.
References Compton, D., et al.: J. Pharmacol. Exp. Ther., 277, 586 (1996), Devane, W., et al.: Science, 258, 1946 (1992),

Applications α-Methylanisalacetone is used in skin sensitization measuring method.
References Fujita, M., et al.: PCT Int. Appl., (2020);

Applications N-(4-aminophenyl)-N2,N2-dimethylglycinamide (cas# 25786-09-8) is a useful research chemical.

Applications 2-(Methoxy-d3)-3-(2-methylpropyl)pyrazine is an intermediate used in the preparation of 2-methoxy-3-alkylpyrazines and their deuterated isotopologues.
References Schmarr, H. G., et al.: J. Label. Compds and Radiopharm., 54, 438 (2011); Gerritsma, D. A., et al.: J. Label. Compds. Radiopharm., 46, 243 (2003)

Applications 2-Bromo-6-methoxybenzoic acid

Applications A photoaffinity reagent.
References Hatanaka, Y. et al: Bioorg. Med. Chem., 2, 1367 (1994); Hatanaka, Y. et al: J. Org. Chem., 59, 383 (1994); Hatanaka, Y. et al: Bioorg. Med. Chem. 2, 1367 (1994)

Applications 2-Ethoxycarbonyl-1-methylpyridinium Iodide is an intermediate in the synthesis of Homarine (H458500), which is a quaternary ammonium base occurring in tissues of marine animals.
References Stein, W., et al.: J. Biol. Chem., 211, 915 (1954), Bystedt, J., et al.: J. Sci. Food Agric., 10, 301 (1959),

Applications 3-Fluoro-2-methoxyphenylboronic acid

Applications (S,S)-(+)-Pseudoephedrine Glycinamide is a commonly used precursor for the synthesis of α-amino acids.
References Myers, A.G., et. al.: Tetrahedron Lett., 36, 4555 (1995)

Applications 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6,7-dimethoxy-3-quinolinecarbonitrile is a useful compound in modelling studies for identifying c-Src inhibitors.
References Sakkiah, S., et al., J. Enzyme Inhib. Med. Chem. 29, 69 (2014); Cao, R., et al., J Mol Model 16, 361 (2010)

Applications A useful synthetic intermediate

Applications α-(2,3-Dimethylphenyl)-α-methyl-1H-imidazole-5-methanol-d3 is the isotope labelled analog of α-(2,3-Dimethylphenyl)-α-methyl-1H-imidazole-5-methanol (D473780); a reagent in the synthesis of Medetomidine (M203250) which is an α2-adrenergic agonist. Also a sedative and analgesic.
References Scheinin, M., et al.: Br. J. Clin. Pharmacol., 24, 443 (1987); Stenberg, D., et al.: J. Vet. Pharmacol. Ther., 10, 319 (1987); Virtanen, R., et al.: Eur. J. Pharmacol., 150, 9 (1988); Cullen, L.K., et al.: Br. Vet. J., 152, 519 (1996); Chen, W., et al.: Faming Zhuanli Shenqing. CN 101921234 A 20101222. Dec 22, 2010