Amino Acids (AA)

Applications N-Acetyl-D-serine is the modified amino acid D-Serine (S270975). D-Serine is a neurotransmitter that is concentrated in the mammalian brain, and is one of the very few amino acids that occur in the D- and L-configurations in significant amounts. D-Serine is an potent agonist of the N-methyl-D-aspartate (NMDA) receptor in the brain, which is associated with schizophrenia. Use of D-Serine has been considered as an additional therapy for refractory schizophrenic patients.
References Heresco-Levy, U., et al.: Biol. Psych., 57, 577 (2005); Mothet, J., et al.: Proc. Nat. Acad. Sci., 97, 4926 (2000); Snyder, S. & Kim, P.: Neurochem. Res., 25, 553 (2000); Tsai, G., et al.: Biol. Psych., 44, 1081 (1998)

Applications 6-Dodecanoate-1,4-anhydro-D-glucitol-d23 is the isotopic form of 6-Dodecanoate-1,4-anhydro-D-glucitol (D494710). 6-Dodecanoate-1,4-anhydro-D-glucitol is used in the synthetic preparation of nonionic surfactant.
References Giacometti, J. et al.: J. Agr. Food Chem., 44, 3950 (1996)

Applications N-Carbobenzoxy-β-alanine has been utilized for various synthesis applications including palladium-catalyzed asymmetric allylation of β-diketones, branched linker that can increase the potency of doxorubicin immunoconjugates, and diacridines that intercalate nucleic acids and inhibit DNA synthesis.
References Sawamura, M., et al.: J. Am. Chem. Soc. 114, 2586 (1997); King, H. D., et al.: Bioconjugate Chem. 10, 279 (1999); Denny, W. A., et al.: J. Med. Chem 28, 1568 (1985)

Applications 6-Chloro1,4-dihydro-1-methyl-4-phenyl-4-quinazolinol-13CD3 is the isotope labelled analog of 6-Chloro1,4-dihydro-1-methyl-4-phenyl-4-quinazolinol. 6-Chloro1,4-dihydro-1-methyl-4-phenyl-4-quinazolinol is used in hydroxyglycine reactions in determining a new synthetic route for phenylquinazoline derivatives.
References Hoefnagel, A.J., et al.: Tetrahedron, 49, 6899 (1993)

Applications 1-Boc-3-aminoazetidine (cas# 193269-78-2) is a compound useful in organic synthesis.
References Jenkins, T., et al.: J. Med. Chem., 50, 566 (2007),

Applications 4-Fmoc-3(S)-morpholinecarboxylic Acid is used to prepare heterocyclic core analogs of a direct thrombin inhibitor.
References Blizard, T., et al.: Bioorg. Med. Chem.Lett., 24, 1111 (2014)

Applications 4-[(4-Methoxyphenyl)methyl]-4-methyl-2-phenyl-5(4H)-oxazolone (cas# 172168-03-5) is a compound useful in organic synthesis.

Applications 1-Methylpiperazine is used in the preparation of 2-(4-Methyl-1-piperazinylmethyl)acrylophenone(MPMAP), an antimicrotubular drug.
References Mallevais, M.L. et al.: Biochimie, 66, 477 (1984);

Applications Fmoc-l-2-pyridylalanine

Applications N-(2-Methoxyethyl)-2,6-xylidine is an intermediate used in the synthesis of Dimethachlor Ethane Sulfonic Acid Sodium Salt (D460283), which is a pesticide metabolite pollutant found in groundwater, surface water, and wastewater.
References Huntscha, S., et al.: J. Chromatogr. A, 1268, 74 (2012); Reemtsma, T., et al.: J. Chromatogr. A, 1271, 95 (2013);

Stability Air Sensitive, Moisture Sensitive
Applications 2-ethoxy-4-formylphenyl 2-methylpropanoate (cas# 188417-26-7) is a useful research chemical.

Applications 4-[(Aminocarbonyl)amino]-D-phenylalanine can be used a reactant in continuous flow solid-phase peptide synthesis.
References Fulop, Ferenc, et al.: PCT Int. Appl., WO 2015128687 A1 20150903 (2015)

Applications 4-Azido-L-phenylalanine-13C9,15N is a labelled analogue of 4-Azido-L-phenylalanine (A922600).

Applications Intermediate in the production of DMEQ-TAD

Applications An intermediate in the production of Rosuvastatin (R700500) derivatives.
References Liu, Y. et al.: Guang. Huag., 39, 54 (2011);

Applications 1-Iodo-3,4-methylenedioxybenzene is an iodinated benzodioxole used in the preparation of various biologically active compounds such as the antiviral and antitumor agents.
References Ikeda, M. et al.: Chem. Pharmac. Bull., 47, 983 (1999);

Applications 4-Chloro-2-methoxypyridine is a reagent in the preparation of cyclopalladated ferrocenylimines as efficient catalysts for the preparation of arylboronate esters.
References Wang, L., et al.: Adv. Synth. Catal., 352, 2002 (2010);

Applications 4-Hydroxy-1-methylpiperidine

Applications 2-Methylpropyl alcohol-D9 is the labelled analogue of 2-Methylpropyl alcohol (I780075). Isobutyl Alcohol is a reagent used in organic reactions. It is used in the synthesis of new fluorinating reagents. It is also used in the lipase-catalyzed production of biodiesel as an energy source.
References Middleton, W. et al.: J. Org. Chem., 04, 574 (1975); Nelson, L. et al.: J. Amer. Oil. Chem. Soc.,

Applications Isotope labelled 3-Methoxy-5-methylaniline (M263310) is a aniline derivative used in the preparation of sulphonamides and aryl amines as antitubercular agents.
References Rajvaidya, S., et al.: J. Institut. Chem., 74, 79 (2002); Haworth, R..D., et al.: J. Chem. Soc. Transact., 123, 2982 (1932);

Applications α,α-Dimethyl-3-phenyl-1,2,4-oxadiazole-5-methanamine Hydrochloride is an intermediate used in the synthesis of Naldemedine (N232550), which is a peripherally selective mu opioid receptor antagonist used in the treatment in pain.
References Brenner, D. et al.: Am. J. Gastroenterol Suppl., 2, 38 (2014);

Applications 4-Hydroxy-3-methoxy-5-nitrobenzoic acid

Applications ethyl(3-methylhexan-2-yl)amine hydrochloride (cas# 1305712-15-5) is a useful research chemical.

Applications 4-Amino-5-cyano-2-methylpyrimidine (cas# 698-29-3) is a compound useful in organic synthesis.

Applications Methyl 4-methoxypicolinate is a useful intermediate for the synthesis of substituted terpyridine ligands for use in protein purification.
References Lin, C., et al.: Tetrahedron, 70, 8520 (2014)

Applications L-threo-Phenylserine is a valuable chiral synthon.

Applications L-4-Hydroxyphenyl-2,6-d2-alanine (CAS# 57746-15-3) is a useful isotopically labeled research compound.

Applications Thieno[2,3-d]pyrimidine derivative.

Applications 5-(1-Methyl-1H-pyrazol-4-yl)-2-pyrimidinemethanamine is a compound useful in organic synthesis.

Applications 2-[2-(2-Aminophenoxy)ethoxy]-4-methyl-benzenamine (cas# 96331-95-2) is a compound useful in organic synthesis.

Applications (4R,4aR,7R,7aR,12bS,14S)-14-Acetyl-9-(benzyloxy)-7-methoxy-1,2,7,7a-tetrahydro-7,4a-ethano-4,12-methanobenzofuro[3,2-e]isoquinoline-3(4H)-carbonitrile, is a metabolite of Buprenorphine (B689570), an Analgesic that demonstrates narcotic agonist-antagonist properties.
References Martin, W.R., et al.: J. Pharmacol. Exp. Ther., 197, 517 (1976), Rance, M.J., Biochem. Pharmacol., 25, 735 (1976), Heel, R.C., et al.: Drugs, 17, 81 (1979),

Stability Light sensitive, Temperature Sensitive
Applications 3-Methyl-1,5-pentanediol Diacrylate is a useful chemical reagent.

Applications 1,4-Benzodioxan-6-methylamine hydrochloride is a reagent that iss used in the preparation of 4-(4-hydroxy-3,5-dimethoxyphenyl)-6,7-dimethoxy-dihydroisoquinolin-3-one.
References Su, B., et al.: Adv. Synth. Catal., 356, 977 (2014);