Amino Acids (AA)

<p>Applications (2S)-2-Hydroxy-2-methyl-3-oxobutanoic Acid Phenylmethyl Ester is an intermediate in the synthesis of (S)-α-Acetolactic Acid (A163805), one of the enantiomers of acetolactate, which is the substrate of Acetolactate decarboxylase, which catalyzes the conversion of both enantiomers of acetolactate to the (R)-enantiomer of acetoin.<br>References Smith, A. M., et al.: J. Org. Chem., 75, 3085 (2010);<br></p>

<p>Applications 4-(2-Aminoethoxy)-3-methoxyphenol-d3 (cas# 1189958-49-3) is a compound useful in organic synthesis.<br></p>

<p>Applications Reactant in the preparation of thiochroman compounds.<br>References Jensen, A.W. et al.; J. Heterocyclic Chem., 37, 1527 (2000)<br></p>

<p>Applications 1-Methoxy-4-(1-propyn-1-yl)benzene is an intermediate in the synthesis of Cis-Anethole (A653355), an organic compound that is widely used as a flavoring substance. It is a derivative of phenylpropene, a type of aromatic compound that occurs widely in nature, in essential oils.<br>References Benelli, G., et al.: Industrial Crops and Products, Vol. 124, P: 236-243 (2018);<br></p>

<p>Applications 6-Hydroxy-8-methoxy-octanoic Acid Methyl Ester-d5 is a compound useful in organic synthesis.<br></p>

<p>Applications N,N-Diisopropyl-3-(2-methoxy-5-methyl-phenyl)-3-phenylpropylamide-d14 (cas# 1795013-34-1) is a compound useful in organic synthesis.<br></p>

<p>Applications N-Methyl-o-phenylenediamine-d3, Dihydrochloride (cas# 1246820-22-3) is a compound useful in organic synthesis.<br></p>

<p>Applications 2-Methyl-N-methyltetrahydro-2-furanmethanamine is the amino component in the synthetic preparation of Mefruside (M205150), a diuretic used for the treatment of edema and hypertension.<br>References Johansen, A., et al.: Euro. J. Epidemiol., 27, 63 (2012); Hasegawa, Y., et al.: Blood. Press. Supple., 1, 10 (2010);<br></p>

<p>Applications Intermediate in the preparation of (+/-)-Iso Myosmine (I821350).<br></p>

<p>Applications Intermediate for the synthesis of labelled Lercanidipine HCl<br></p>

<p>Applications (E)-(3,4-Dihydro-7-methoxy-1(2H)-naphthalenylidene)acetonitrile is an intermediate used in the synthesis of (E)-N-[2-(3,4-Dihydro-7-methoxy-1(2H)-naphthalenylidene)ethyl]acetamide(Agomelatine Impurity) (D450485), which is an impurity of Agomelatine (A430000) which is a melatoninergic agonist and selective antagonist of 5-HT2C receptors and used in the treatment of major depressive disorder. Agomelatine Impurity 2<br>References Yous, S., et al.: J. Med. Chem., 35, 1484 (1992), Zhdanova, I., et al.: J. Clin. Endocrinol. Metab., 86, 4727 (2001), Cajochen, C., et al.: J. Pineal Res., 35, 149 (2003),<br></p>

<p>Applications 4-Bromo-5-methylbenzene-1,3-diol is used in the synthesis of phenanthrenes which displays antioxidant and anti-inflammatory activities.<br>References Kanekar, Y., et al.: Eur. J. Med. Chem., 67, 454-463 (2013)<br></p>

<p>Applications A 9-substituted derivative of the polycyclic aromatic hydrocarbon (PAH) Anthracene (A678400).<br></p>

<p>Applications 3-(2-Methyl-1,3-dioxolan-2-yl)-6-methylpyridine is used in the synthesis and biological activity of metabolites of the antidiabetic, antihyperglycemic agent Pioglitazone (P471000).<br>References Defronzo, R., et al.: Diabetes, 1988, 37, 667 (1988), Hulin, B., et al.: J. Med. Chem., 35, 1853 (1992), Iwanishi, M., et al.: Metabolism, 42, 1017 (1993),<br></p>

<p>Applications N-(1-Naphthyl-d7-methyl)methylamine (cas# 1189686-07-4) is a compound useful in organic synthesis.<br></p>

<p>Applications Dimethyl L-Aspartate Hydrochloride was used in the synthesis of enzyme and pH dual responsive L-amino acid based biodegradable polymer nanocarrier that can be used for multidrug delivery to cancer cells.<br>References Saxena, S., et al.: J. Polym. Sci. Pol. Chem., 54, 3279 (2016);<br></p>

<p>Applications 3-Methoxy-2-methylbenzoic acid<br></p>

<p>Applications 4-Amino-1-[2-deoxy-3,5-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]-β-D-erythro-pentofuranosyl]-1,3,5-triazin-2(1H)-one is an intermeidate in the synthesis of metabolites of Azadeoxycytidine (A796950), as neoplasm inhibitor.<br>References Cihak, A., et al.: Eur. J. Cancer, 14, 117 (1978),<br></p>

<p>Applications 1-(Cyano-(4-methoxyphenyl)ethyl)cyclohexanol-d11 is an intermediate in the synthesis of N,O-Didesmethylvenlafaxine, a metabolite of Venlafaxine.<br>References Klamerus, K. J., et al.: J. Clin. PHarmacol., 32, 716 (1992), Gelenberg, A.J., et al.: J. Am. Med. Assoc., 283, 3082 (2000)<br></p>