Amino Acids (AA)

<p>Applications Intermediate for the synthesis of glucuronide conjugates of trans-Resveratrol<br>References Learmonth, D.A., et al.: Bioconjug. Chem., 14, 262 (2003),<br></p>

<p>Applications 4-Dimethylamino-4'-methylazobenzene (cas# 3010-57-9) is a useful research chemical.<br></p>

<p>Applications 1-Amino-4-methylpyridinium Iodide is a useful synthetic intermediate. It is used to prepare new rhodanine analogs as potential antitumor agents.<br>References Li, Y., et al.: Chinese Chemical Letters, 23, 415 (2012)<br></p>

<p>Applications Aranthol Maleate is an intermediate in the synthesis of Isometheptene (I821325), a sympathomimetic amine that shows some antihypertensive activity.<br>References Vidrio, H. et al.: J. Pharmacol. Exp. Therap., 187, 308 (1973); Taylor, W.G. et al.: Drug Metab. Disp., 5, 564 (1977);<br></p>

<p>Applications N,N-Bis-desethyl, N-Methyl Entacapone-d3 is the isotope analog of N,N-Bis-desethyl, N-Methyl Entacapone which is an impurity of Entacapone (E558500). The (E)-Isomer of Entacapone which is a polymorphic form A. Peripherally acting inhibitor of catechol-O-methyl transferase (COMT), an enzyme involved in the metabolism of catecholamine neurotransmitters and related drugs. Antiparkinsonian.<br>References Karlsson, M., et al.: J. Pharm. Biomed. Anal., 10, 593 (1992), Nissinen, E., et al.: Arch. Pharmacol., 346, 262 (1992), Wikberg, T., et al.: Eur. J. Drug Metab. Pharmacokinet., 18, 359 (1993),<br></p>

<p>Applications N-Methyl-d3-acetamide-2,2,2-d3 (CAS# 3669-73-6) is a useful isotopically labeled research compound.<br></p>

<p>Applications 4-[(2-Hydroxybenzoyl)amino]-1-methyl-3-propyl-1H-pyrazole-5-carboxamide is an intermediate used in the synthesis of Desethyl Gendenafil (D290470), which could be a possible metabolite of Gendenafil (G349960) based on the metabolic pathway of Sildenafil (S435000, Citrate salt), an analogue of Gendenafil.<br></p>

<p>Applications 2-Iodo-2-methylpropane-d9 (CAS# 61207-61-2) is a useful isotopically labeled research compound.<br></p>

<p>Applications Isotope labelled N-Fmoc-glycine is an N-Fmoc-protected form of Glycine (G615990). Glycine is a nonessential amino acid that acts as an inhibitory neyrotransmitter in the vertebrate central nervous system. Glycine also posesses cytoprotective against oxidant damage in the kidney.<br>References Eulenberg, V., et al.: Trend. Biochem. Sci., 30, 325 (2005); Gundersen, R., et al.: Acta Anaesth. Scand., 49, 1108 (2005); Lockart, R. &amp; Eagle, H.: Science, 129, 252 (1959); Sogabe, K., et al.: Kidn. Int., 50, 845 (1996)<br></p>

<p>Applications 2-Bromo-5-methylthiazole<br></p>

<p>Applications 5-Amino-3-methylisoxazole is a widely used reactant. 5-Amino-3-methylisoxazole has been used as a reactant for the preparation of heterocycle fused pyridinecarboxylic acids.<br>References Volochnyuk, D.M., et. al.: J. Comb. Chem., 12, 510 (2010)<br></p>

<p>Applications N-(2-Hydroxyethyl)-4-methylbenzenesulfonamide (cas# 14316-14-4) is a compound useful in organic synthesis.<br>References Reinhardt, G., et al.: J. Appl. Biochem., 2, 495 (1980),<br></p>

<p>Applications Desmethyl Metsulfuron-methyl is a degradation product of Metsulfuron-methyl (MTSM), a residual sulfonylurea herbicide that kills broadleaf weeds and some annual grasses.<br>References Ollis, D., et al.: Environ. Sci. Technol., 19, 480 (1985); Malouki, M., et al.: J. Toxicol. Environ. Chem., 55, 235 (1996); Vulliet, E., et al.: J. Agri. Food Chem., 50, 1081 (2002);<br></p>