Amino Acids (AA)

Applications 2-(Chloromethyl)-6-methoxy-4-methylpyridine-D3 is a deuterium labelled analogue of 2-(Chloromethyl)-6-methoxy-4-methylpyridine (C587835), which is a trisubstituted Pyridine based building block. Pyridine (P991280) is a heterocyclic ring base present in many biologically active compounds like the vitamins niacin and pyridoxal. Pyridine is used in dehalogenation reactions and can be used as a base in condensation reactions.
References Egyed, J. et al.: Bull. Soc. Chim. Fra., 11, 3014 (1973); Li, Y. et al.: Wuli HUa. Xueb., 14, 1048 (1998);

Applications 4-Bromo-2-(1-methylethyl)phenol is used in the synthesis of biphenyl proteomimetics as estrogen receptor-α coactivator binding inhibitors. As well, used in the production of thyroid hormone receptor specific analogs.
References Williams, A. et al.: Org. Lett., 11, 5370 (2009); Ocasio, C. et al.: Bioorg. Med. Chem. Lett., 16, 762 (2008);

Applications H-D-Phe-Homopro-Arg-pNA.2 Acetate is a useful organic reagent.

Applications rac-α-N-Boc-Amino-4-pyridineaceic Acid is a reagent used in the preparation of lactam-containing diaminoalkanes, β/α-amino acids and derivatives of Xa inhibitors.

Applications 3-Acetyl-1-Boc-pyrrolidine is a boc protected reagent that is used for selective inhibitors of H. influenzae TrmD that mimic tRNA interaction by inducing TrmD lid domain ordering.
References Hill, P.J., et al.: J. Med. Chem., 56, 7278 (2013);

Applications 2-(4-Boc-piperazino)pyrimidine-5-boronic acid pinacol ester

Applications 7-Ethoxy-4-methylcoumarin (cas# 87-05-8) is a useful research chemical.

Applications 3-Cyclopropyl-4-methyl-1h-pyrazole-5-carboxylic Acid can be used to prepared to be used as trace amine associated receptors (TAAR1).
References Cecere, G., et.al.: PCT Int. Appl., 112, (2016);

Applications 3-Fluoro-2-methoxy-benzenesulfonyl-d3 Chloride is the isotope labelled analog of 3-Fluoro-2-methoxy-benzenesulfonyl Chloride (F593265), which is a derivative of 2-Fluoroanisole (F587670); a useful synthetic intermediate with antifungal activity.
References Pinto, M. F. S., et al.: J. Mol. Struc.: Theochem., 539, 303-310 (2001)

Applications 1,2:5,6-Di-O-isopropylidene-α-D-glucofuranose 3-p-Toluenesulfonate is used in the synthesis of a highly constrained adenosine derivative of 5’-Deoxy-5’-methylthioadenosine (MTA) which is 4’,4’-spirothietane-2’,N3-cycloadenosine.
References De Carvalho, G. S. G., et al.: Tetrahedron Lett., 50, 463-466 (2009)

Applications Intermediate for the synthesis of glucuronide conjugates of trans-Resveratrol
References Learmonth, D.A., et al.: Bioconjug. Chem., 14, 262 (2003),

Applications A useful deuterated synthetic intermediate.

Applications 1-[4-[3-(4-Acetyl-2-methoxyphenoxy)propoxy]-3-ethoxyphenyl]ethanone is an impurity of Iloperidone (I267200); an atypical antipsychotic drug used in the treatment of schizophrenia.
References Ichikawa, J., et al.: Brain Res., 956, 349 (2002); Potkin, S. G., et al.: J. Clin. Psychopharm., 28, S4 (2008)

Applications 5-Bromo-2-(N-methylamino)pyridine is useful for the synthetic preparation of halo aminopyridines.
References Sun, C., et al.: ACS Omega, 4, 10534 (2019)