Amino Acids (AA)

Applications Boc-D-serine is D-serine (S270975) with amine protected from eletrophiles by tert-butyloxycarbonyl group in organic synthesis. Boc-D-serine can be used to synthesize acetamido-methoxypropionamides such as Desacetyl Desmethyl Lacosamide (D288325) which is a potent anticonvulsant.
References Letiran, A., et al.: J. Med. Chem., 45, 4762 (2002); Wadavrao, S., et al.: Synthesis, 45, 3383 (2013)

Applications L-Aspartic Acid salcium salt is used in three high-dose oral calcium salts model (CaCO3, CaCl2, Ca-aspartate-hydrochloride) which has effects on acid-base metabolism, plasma electrolytes and urine parameters in rats.
References Classen, H.G., et al.: Experim. Clin. Pharmacol., 17, 437 (1995),

Applications 4-(N-Boc-amino)cyclohexanone is an intermediate in the synthesis of tert-Butyl 1,7-diazaspiro[3.5]nonane-1-carboxylate (B692795). tert-Butyl 1,7-diazaspiro[3.5]nonane-1-carboxylate is a reagent in the preparation of -[4-fluoro-3-(piperazin-1-ylcarbonyl)benzyl]-4,5-dimethylpyridazin-3(2H)-ones as a potent poly(ADP-ribose) polymerase-1 inhibitors active in BRCA deficient cells.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Ferrigno, F., et al.: Bioorg. Med. Chem. Lett., 20, 1100 (2010);

Applications Toxicity is similar to salicylic acid. Used in manufacturing of dyes.

Applications N-[(1,1-Dimethylethoxy)carbonyl]glycine Methyl Ester is a amino acid glycine (G615990) derivative, used widely in various synthetic preparations of pharmaceutical goods and antioxidants. N-[(1,1-Dimethylethoxy)carbonyl]glycine Methyl Ester can be used in the preparation of Pregabalin (P704800), a GABA analogue used as an anticonvulsant.
References Ko, E.H., et al.: J. Am. Chem. Soc., 133, 462 (2011); Heller, S.T., et al.: Org. Lett., 12, 4572 (2010); Taylor, C.P., at al.: Epilepsy Res., 14, 11 (1993), Field, M.J., et al.: Pain, 80, 391 (1999)

Applications 4-(3-Methoxypropoxy)-2,3-dimethylpyridin-1-ium-1-olate is used in preparation of Picolylsulfides and related drugs by using Esterification and Thioetherification as the key steps.
References Wang, D., et al.: Faming Zhuanli Shenqing, (2019);

Applications 1,2-Bis(4-methoxyphenyl)ethanone is an intermediate used to synthesize aryl substituted imidazole with estrogen receptor binding abilities and furans as antagonists with selectivity for the estrogen receptor alpha.
References Wiglenda, T., et al.: J. Med. Chem., 50, 1475 (2007); Mortensen, D., et al.: Bioorg. Med. Chem. Lett., 11, 2521 (2001)

Applications 1-(4-methyl-3-cyclohexen-1-yl)ethanone is an essential oil found in Cedrus atlantica wood and orange peels.
References Uehara, Ayaka, et al.: Phytochemistry, 144, 208-215 (2017); Liu, Bo, et al.: Yancao Keji, (9), 52-56 (2014)

Applications 1-TERT-BUTYL 3-METHYL 3-HYDROXYPYRROLIDINE-1,3-DICARBOXYLATE (cas# 942190-61-6) is a useful research chemical.

Applications N-[(S)-(2,3,4,5,6-Pentafluorophenoxy)phenoxyphosphinyl]-L-alanine 1-Methylethyl Ester is a reactant in the synthesis of phosphoramidate imidazo[2,1-f][1,2,4]triazine-4-amine adenosine prodrugs that can increase anti-HCV activity.
References Tyndall, E.M., et. al.: Bio. Med. Chem. Lett., 25, 869 (2015)

Applications An aspartic acid derivative used in stereoselective synthesis; a potent, selective proteasome inhibitor.
References Elofsson, M., et al.: Chem. Biol., 6, 811 (1999),Myung, J., et al.: Mol. Cell., 7, 411 (2001), Fukatsu, K., et al.: J. Med. Chem., 45, 4212 (2002),

Applications A glutarimide that shows anticonvulsant activity.
References Witiak, D.T., et al.: J. Med. Chem., 15, 1117 (1972),

Applications Fmoc-Cop is used in the synthesis of disubstituted pyrimidines as Lck inhibitors.
References Hunt, J., et al.: Bioorg. Med. Chem. Lett., 19, 5440 (2009)