Amino Acids (AA)

Impurity Azathioprine EP Impurity C
Applications 5-Chloro-1-methyl-4-nitroimidazole (cas# 4897-25-0) is a compound useful in organic synthesis.

Applications (3R)-Tetrahydrofuran-3-yl 4-Methylbenzenesulfonate is derived from (R)-(-)-3-Hydroxytetrahydrofuran (H957760), which is a versatile chemical reactant used in the synthesis of pharmaceutical agents.
References Hrapchak, M., et al.: J. Labelled. Comp. Radiopharm., 57, 687 (2014);

Applications N-(4-Cyanophenyl)-glycine (cas# 42288-26-6) is a compound useful in organic synthesis.

Applications Labelled L-Ornithine. A non-essential amino acid for human development but is required intermediate in arginine biosynthesis. L-Ornithine is found in virtually all vertebrate tissues as well as incorporated into proteins, such as tyrocidine. Isolation from chicken excreta.
References Fattori, D. et al.: J. Med. Chem., 50, 550 (2007); Gomez-Alonso, S. et al.: J. Agric. Food Chem., 55, 608 (2007); Subramaniam, R. et al.: Bioorg. Med. Chem. Lett., 18, 3333 (2008);

Applications 2-Chloro-3-methylaniline (cas# 29027-17-6) is a useful research chemical.

Stability Hygroscopic
Applications A labelled metabolite of Methyl isocyanate.
References Slatter, J. G., et al.: Chem. Res. Toxicol., 4, 157 (1991),

Stability Hygroscopic
Applications Galactosylceramides play an important roles in promoting the regulation of nerve cells, regulating protein kinase C activities and modulating the function of the hormone receptor. It has shown to have significant immunostimulatory and anti-umor activity in mice with liver metastasis of the Colon26 adenocarcinoma.
References Morita, M., et al.: J. Med. Chem., 38, 2176 (1995), Sakai, T., et al.: J. Med. Chem., 42, 1836 (1999),

Stability Hygroscopic, Temperature Sensitive
Applications A carnitine ester of unsaturated fatty acid. Used in the studies of fibroblasts in long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency and fatty acid oxidation disorders.
References Gross R.W., et al.: J. Biol. Chem., 258, 5221 (1983),

Applications 3-Methyl-2-hexanamine HCl Salt is more stable and easier to purify compared to the free base.

Applications L-Valine is an essential amino acid and one of 20 proteinogenic amino acids. L-Valine cannot be manufactured by the body and must be acquired through diet or supplementation. L-valine is found in grains, dairy products, mushrooms, meats, peanuts and soy proteins. L-Valine has been used in studies to attenuate arrhythmias and induce hypotensive effects.
References Choi, C.W. et al.: Anim. Feed Sci. Technol., 102, 15 (2002); Kolarski, D. et al.: Krmiva, 30, 155 (1988); Oba, M. et al.: J. Dairy Sci., 93, 2044 (2010); Mitrega, K. et al.: Pharmacol. Res., 64, 218 (2011);

Applications 2'-Deoxy-N3-methyluridine (cas# 24514-32-7) is a useful research chemical.

Applications D-Glutamic acid 1-tert-butyl ester is a protected form of D-Glutamic acid (G596965). D-Glutamic acid is an unnatural isomer of L-Glutamic acid (G596960), and is found in bacterial cell wall peptidoglycan of gram-positive and gram-negative bacteria. D-Glutamic acid also occurs as poly-gamma-Glutamic acid, which is a weak immunogen but is capable of acting as a hapten (a small molecule that induces the production of antibodies, as well as binding to them).
References Dougherty, T., et al.: J. Bacteriol., 175, 111 (1993); Goodman, J. & Nitecki, D.: Immunology, 13, 577 (1967); Robinson, T.: Life Sci., 19, 1097 (1976)

Applications 2-Methyldibenzothiophene, is an alkyldibenzothiophene present in crude oil. Research concerning the biodegradation of Dibenzothiophene by different types of bacteria is a currently being carried out, as these bacteria have the ability to breakdown other harmful PAH’s as well. This may be used in removing spilled oil from marine and terrestrial environments.
References Boberg, F., et al.: Erdoel & Kohle, Erdgas, Petrochemie, 47, 187 (1994); Tanaka, Y., et al.: Applied Microbiology and Biotech., 59 (2), 325 (2002); Prince, R., Spill Sci. Tech. Bulletin, 8 (2), 145 (2003);

Applications Useful in the study of tyrosine-phosphorylation, which has been linked with the malignant transformation of cells by some RNA tumour viruses.
References Sefton, B.M., et al.: Cell, 20, 807 (1980), Erikson, R., et al.: Perspect. Virol., 11, 93 (1981), Lee, E-S, et al.: J. Org. Chem., 59, 2086 (1994)

Applications A Boc-protected bifunctional linking reagent.
References Jimenez-Castells, C., et al.: Bioorg. Med. Chem. Lett., 17, 5155 (2007), Carmona, S., et al.: Mol. Pharm., 6, 706 (2009), Nagahori, N., et al.: Biochem., 48, 583 (2009),

Applications 4-Methoxy-3-nitrobenzonitrile

Applications 2-Methylpropylamine is used in the synthesis of arylsulfonamide inhibitors that act upon afflictions of osteoarthritis. In addition, it is used in the synthesis of novel reservatrol amide derivatives that act as anti-tumor agents.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Yao, Ri-Sheng. et al.: Eur. J. Med. Chem. Lett., 62, 222 (2013); Nuti, E. et al.: Eur. j. Med. Chem., 62, 379 (2013)

Applications S-Methyl-L-cysteine is a substrate in the catalytic antioxidant system mediated by methionine sulfoxide reductase A (MSRA). It has been studied as a theurapeutic for neurodegenerative diseases including Parkinson′s.
References Wassef, R., et al.: J. Neurosci., 21, 12808 (2007)

Applications 6-Methylheptanoic acid is used as a reagent to synthesize analogues of Eponemycin, an antibiotic that also exhibits anti-angiogenic activity by inhibiting proteasome function. 6-Methylheptanoic acid naturally occurs as a component of the scent chemical of the brushtail possum.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References McLean, S., et al.: J. Chem. Ecol., 38, 1318 (2012); Oikawa, T., et al.: Biochem. Biophys. Res. Comm., 181, 1070 (1991); Sin, N., et al.: Bioorg. Med. Chem., 6, 1209 (1998)

Applications N-(4-Bromo-2-methylphenyl)-2-chloroacetamide (cas# 96686-51-0) is a useful research chemical.

Applications N-Epsilon-acetyl-l-lysine is used in the metabolomics study on the combined effect of cocaine and ethanol via liquid chromatography-mass spectrometry metabolomics approach.
References Sanchez-Lopez, E., et al.: J. Pharm. Biomed. Anal., 140, 313 (2017)

Applications Thiodiglycolic Acid-d4 acts as a reagent for the synthesis of metabolites of S-carboxymethyl-L-cysteine and S-methyl-L-Cysteine and of some isotoically labelled (2H, 13C) analogs.
References Meese, C. O., et al.: Archiv der Pharmazie, 323, 957 (1990)

Applications 2-Chloro-L-phenylalanine

Impurity Imatinib EP Impurity G
Applications 1-Methylpiperazine (Imatinib EP Impurity G) is used in the preparation of 2-(4-Methyl-1-piperazinylmethyl)acrylophenone(MPMAP), an antimicrotubular drug. It is a COVID19-related research product.
References Mallevais, M.L. et al.: Biochimie, 66, 477 (1984);

Applications A labelled metabolite of Toluene.
References Gargas, M., et al.: Toxicol. Appl. Pharmacol., 98, 87 (1989), Commandeur, J., et al.: Pharmacol. Rev., 47(2), 271 (1995), Campo, P., et al.: Neurotoxicol. Teratol., 21, 427 (1999), Lohse, C., et al.: J. Agr. Food Chem., 48, 5913 (2000),

Stability Very Hygroscopic
Applications 1-O-Dimethoxytrityl-2-(N-Fmoc)-4-Aminobutyl)-1,3-propanediol is a useful reagent for the synthesis of acridine and​/or lipid containing oligodeoxyribonucleotides.
References Marasco, C. J., et al.: Tetra. Lett., 35, 3029 (1994)

Applications 4-Amino-2-methyl-5-pyrimidinemethanesulfonic acid is used in the biosynthesis of Thiamine (T344185) in yeast.
References White, R., et al.: Journal of the American Chemical Society, 104, 4934 (1982).

Applications Used in the synthesis of selective β-adrenergic blocker Metoprolol.
References Su, W., et al.: J. Chem. Res., 6, 414 (2004),

Applications Guaiacol-beta-D-glucopyranoside, is a Guaiacol Conjugate, that has shown to present in fermentation of grapes that had been exposed to bushfire smoke and can potentially yield unpalatable, smoke-affected wine.
References Hayasaka, Y.m et al.: J. Arg. Food Chem., Vol. 58, Issue 4, P: 2076; 2081 (2010);

Applications L-Glutamic Acid-d5 is an non-essential amino acid. Its salt form (glutamate) is an important neurotransmitter that plays a key role in long-term potentiation and is important for learning and memory. It is also a key molecule in cellular metabolism.
References McEntee, W., et al.: Psychopharmacology, 111, 391 (1993), Manev, H., et al.: Mol. Pharmacol., 36, 106 (1989)

Stability Hygroscopic
Applications This compound is used in the production of antiviral peptides and beta-lactam anti-biotics.
References Ogasa, T. et al.: Chem. Pharm. Bull., 37, 315 (1989); Dettner, F. et al.: Angew. Chem. Int. Ed., 48, 1856 (2009);

Applications 2-Oxo-3-methylbutanoic acid (cas# 759-05-7) is a useful research chemical.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package