Peptides

A synthetic peptide for use as a blocking control in assays to test for specificity of METTL5 antibody, catalog no. 70R-3352

A synthetic peptide for use as a blocking control in assays to test for specificity of GLIPR1L1 antibody, catalog no. 70R-4567

A synthetic peptide for use as a blocking control in assays to test for specificity of PAPOLB antibody, catalog no. 70R-4959

A synthetic peptide for use as a blocking control in assays to test for specificity of ASL antibody, catalog no. 70R-1176

A synthetic peptide for use as a blocking control in assays to test for specificity of NKIRAS1 antibody, catalog no. 70R-5878

A synthetic peptide for use as a blocking control in assays to test for specificity of SSTR1 antibody, catalog no. 70R-9812

Myelin oligodendrocyte glycoprotein (MOG) is a member of the immunoglobulin (Ig) protein superfamily and is expressed exclusively in the central nervous system (CNS) on the surface of myelin sheaths and oligodendrocyte processes. MOG is expressed at the onset of myelination, and therefore is a potential marker for oligodendrocyte maturation.MOG contains an extracellular domain, a transmembrane domain, a cytoplasmic loop, a membrane-associated region and a cytoplasmic tail. MOG may function as a cell surface receptor or cell adhesion molecule. -Fifteen different alternatively spliced isoforms have been detected in humans. These are present either on the cell surface, the endoplasmic reticulum in the endocytic system, or in secreted form.The secreted form of MOG may trigger autoimmunity if released into the cerebrospinal fluid and periphery. MOG is thought to be a key target for autoantibodies and cell-mediated immune responses in inflammatory demyelinating diseases such as multiple sclerosis (MS) and is therefore widely studied in this field.Fragment (35-51) of the human MOG can be rapidly degraded by the serine protease CatG. Conversion of arginine 46 to citrulline in this peptide reduces the sensitivity of the citrullinated MOG 35-51 peptide to degradation. This peptide has an uncharged C-terminal amide.

A synthetic peptide for use as a blocking control in assays to test for specificity of HSPB8 antibody, catalog no. 70R-2327

Angiotensin A is a research tool that is used to study the activation of angiotensin receptors. It can be used to identify ligands and receptors and to investigate the pharmacology of peptides. Angiotensin A is soluble (1-2 mg/ml) in water, dimethyl sulfoxide (DMSO), and phosphate buffered saline. It has a CAS number of 51833-76-2.

A synthetic peptide for use as a blocking control in assays to test for specificity of TXNIP antibody, catalog no. 70R-2031

A synthetic peptide for use as a blocking control in assays to test for specificity of MAGED2 antibody, catalog no. 70R-9922

A synthetic peptide for use as a blocking control in assays to test for specificity of NBL1 antibody, catalog no. 70R-5414

Bis-dPEG®2-Acid is a PEG polymer categorised as homobifunctional PEG (X-PEG X). Used as a linker, bis-dPEG®2-Acid is used to attached PEG to proteins, peptides, oligonucleotides, nanoparticles and small molecules via pegylation, a bioconjugation technique.

A synthetic peptide for use as a blocking control in assays to test for specificity of SERPINI2 antibody, catalog no. 70R-9424

A synthetic peptide for use as a blocking control in assays to test for specificity of Prdm12 antibody, catalog no. 70R-9558

A synthetic peptide for use as a blocking control in assays to test for specificity of ACSL4 antibody, catalog no. 70R-7155

A synthetic peptide for use as a blocking control in assays to test for specificity of C21orf45 antibody, catalog no. 70R-3295

A synthetic peptide for use as a blocking control in assays to test for specificity of HNRNPU antibody, catalog no. 70R-4648

Cysteine peptide (Ac RFAAKAA COOH) is used in combination with Lysinepeptide (Ac RFAACAA COOH) in the Direct Peptide Reactivity Assay (DPRA) test.
Direct Peptide Reactivity Assay is used in cosmetic applications for the characterization of the skin sensitizing potential of a substance, framed by OECD Guideline no 442.
The molecular initiating event (MIE) in skin sensitization is a binding between epidermal proteins and the sensitizing chemical substance. MIE is part of the adverse outcome pathway (AOP) of skin sensitization.
It is thanks to the properties of Lysine peptide and Cysteine peptide that the chemical binding will be able to take place, so these synthetic heptapeptides will mimic the reaction of a skin exposed to a substance.
Binding between nucleophilic proteins and electrophile substance will be measured by High Performance Liquid Chromatography (HPLC). Therefore, the decrease in Lysine peptide and Cysteine peptide levels will be a sign of sensitizing event. Depending on the rate of depletion, the sensitizing character of a molecule will be determined (see table at the bottom of the page).
In chemico DPRA test also has wider applications such as hazard classification in cosmetics, but also for pharmaceuticals and biocides. It is a good alternative to animal experimentation.

A synthetic peptide for use as a blocking control in assays to test for specificity of VTN antibody, catalog no. 70R-9584

A synthetic peptide for use as a blocking control in assays to test for specificity of NOL4 antibody, catalog no. 70R-4720

A synthetic peptide for use as a blocking control in assays to test for specificity of ASB8 antibody, catalog no. 70R-5837

A synthetic peptide for use as a blocking control in assays to test for specificity of USP48 antibody, catalog no. 70R-6673

A synthetic peptide for use as a blocking control in assays to test for specificity of NLGN4X antibody, catalog no. 70R-6162

A synthetic peptide for use as a blocking control in assays to test for specificity of RAD23B antibody, catalog no. 70R-3309

A synthetic peptide for use as a blocking control in assays to test for specificity of PHGDH antibody, catalog no. 70R-5256

A synthetic peptide for use as a blocking control in assays to test for specificity of CYP4F3 antibody, catalog no. 70R-7504

A synthetic peptide for use as a blocking control in assays to test for specificity of ZNF389 antibody, catalog no. 70R-9065

A synthetic peptide for use as a blocking control in assays to test for specificity of TST antibody, catalog no. 70R-2439

A synthetic peptide for use as a blocking control in assays to test for specificity of EMP2 antibody, catalog no. 70R-1915

A synthetic peptide for use as a blocking control in assays to test for specificity of RHOD antibody, catalog no. 70R-5765

A synthetic peptide for use as a blocking control in assays to test for specificity of MARCKS antibody, catalog no. 70R-10037

A synthetic peptide for use as a blocking control in assays to test for specificity of GSTK1 antibody, catalog no. 70R-4024

A synthetic peptide for use as a blocking control in assays to test for specificity of ZNF205 antibody, catalog no. 20R-1197

A synthetic peptide for use as a blocking control in assays to test for specificity of A4GALT antibody, catalog no. 70R-7416

A synthetic peptide for use as a blocking control in assays to test for specificity of CLIC3 antibody, catalog no. 70R-8068

A synthetic peptide for use as a blocking control in assays to test for specificity of TAP1 antibody, catalog no. 70R-5960

A synthetic peptide for use as a blocking control in assays to test for specificity of NT5C1B antibody, catalog no. 70R-4405

A synthetic peptide for use as a blocking control in assays to test for specificity of TMTC4 antibody, catalog no. 70R-6839

A synthetic peptide for use as a blocking control in assays to test for specificity of CRISPLD2 antibody, catalog no. 70R-7445

Z-Arg-Arg-AMC is an activator of the receptor tyrosine kinase (RTK) system. It binds to the extracellular domain of RTKs, such as epidermal growth factor receptors (EGFR) and fibroblast growth factor receptors (FGFR), and activates these receptors. This compound has been shown to activate EGFR and FGFR at low concentrations and inhibit their activation at high concentrations. Z-Arg-Arg-AMC has also been shown to be a potent inhibitor of protein interactions with a Kd of approximately 1 μM, which makes it a useful research tool for studying protein interactions.

A synthetic peptide for use as a blocking control in assays to test for specificity of PAF1 antibody, catalog no. 70R-10322

A synthetic peptide for use as a blocking control in assays to test for specificity of CCDC11 antibody, catalog no. 70R-4249

A synthetic peptide for use as a blocking control in assays to test for specificity of SLC5A7 antibody, catalog no. 70R-7211

A synthetic peptide for use as a blocking control in assays to test for specificity of CNN3 antibody, catalog no. 70R-9960

A synthetic peptide for use as a blocking control in assays to test for specificity of ZSWIM3 antibody, catalog no. 70R-3646

A synthetic peptide for use as a blocking control in assays to test for specificity of RPS29 antibody, catalog no. 70R-1428

A synthetic peptide for use as a blocking control in assays to test for specificity of ATP6V0E2 antibody, catalog no. 70R-2843

A synthetic peptide for use as a blocking control in assays to test for specificity of SOX7 antibody, catalog no. 70R-8385

A synthetic peptide for use as a blocking control in assays to test for specificity of GCK antibody, catalog no. 70R-10324

A synthetic peptide for use as a blocking control in assays to test for specificity of CPEB2 antibody, catalog no. 70R-4851

Influenza virus-specific hemagglutinin
Flu-HA-B (306-318) is a short part of Influenza hemagglutinin (HA). Influenza hemagglutinin is glycoprotein found on the surface of influenza viruses. HA allows Influenza virus to bind factor on the surface of the cell membrane. HA is also responsible for the membrane fusion with the viral envelope.
Flu-HA-B (306-318) DRB1*01:01
Flu-HA-B (306-318) is a classical antigenic peptide which is used as positive control to bind DRB1*01:01 for peptide/MHC-binding assay. It has been demonstrated the ability of HLA-DRB1*01:01 to present Flu-HA-B (306-318).

A synthetic peptide for use as a blocking control in assays to test for specificity of HERC5 antibody, catalog no. 70R-5524

A synthetic peptide for use as a blocking control in assays to test for specificity of SLC39A9 antibody, catalog no. 70R-6753

A synthetic peptide for use as a blocking control in assays to test for specificity of LRRC2 antibody, catalog no. 70R-3937

A synthetic peptide for use as a blocking control in assays to test for specificity of C19orf46 antibody, catalog no. 70R-6674

A synthetic peptide for use as a blocking control in assays to test for specificity of PTP4A3 antibody, catalog no. 70R-2657

A synthetic peptide for use as a blocking control in assays to test for specificity of CST8 antibody, catalog no. 70R-3907

A synthetic peptide for use as a blocking control in assays to test for specificity of HNMT antibody, catalog no. 70R-9830

A synthetic peptide for use as a blocking control in assays to test for specificity of EPB41 antibody, catalog no. 70R-3846

A synthetic peptide for use as a blocking control in assays to test for specificity of KCNA7 antibody, catalog no. 70R-5117

A synthetic peptide for use as a blocking control in assays to test for specificity of Aste1 antibody, catalog no. 70R-8231

A synthetic peptide for use as a blocking control in assays to test for specificity of SLC25A32 antibody, catalog no. 70R-6474

Blocker of Nav1.1 / 1.2 / 1.3 / 1.4 / 1.6 / 1.7

A synthetic peptide for use as a blocking control in assays to test for specificity of CCNB1 antibody, catalog no. 70R-7825

A synthetic peptide for use as a blocking control in assays to test for specificity of RCE1 antibody, catalog no. 70R-1807

A synthetic peptide for use as a blocking control in assays to test for specificity of ALAD antibody, catalog no. 70R-3445

A synthetic peptide for use as a blocking control in assays to test for specificity of SF3A1 antibody, catalog no. 70R-4828

Selective antagonist of the alpha(1A)-adrenoceptor

A synthetic peptide for use as a blocking control in assays to test for specificity of TMED10 antibody, catalog no. 70R-7250

A synthetic peptide for use as a blocking control in assays to test for specificity of ACVR1C antibody, catalog no. 70R-7481

A synthetic peptide for use as a blocking control in assays to test for specificity of UMPS antibody, catalog no. 70R-2670

A synthetic peptide for use as a blocking control in assays to test for specificity of INTS12 antibody, catalog no. 70R-9072

A synthetic peptide for use as a blocking control in assays to test for specificity of SFT2D3 antibody, catalog no. 70R-10139

A synthetic peptide for use as a blocking control in assays to test for specificity of RHOT1 antibody, catalog no. 70R-5953

A synthetic peptide for use as a blocking control in assays to test for specificity of UST antibody, catalog no. 70R-6963

A synthetic peptide for use as a blocking control in assays to test for specificity of AHCY antibody, catalog no. 70R-2721

Obestatin is a peptide that was originally isolated from rat and mouse brain. It is a potent inhibitor of Kv1.3 and Kv1.5 potassium channels, with an IC50 of about 1 nM for both channels, but has no effect on other ion channels. Obestatin also inhibits the binding of antibodies to epitopes on the surface of cells, which may be due to its ability to inhibit cell-cell adhesion. The antibody-binding activity of obestatin is also inhibited by peptides corresponding to residues in the N-terminal region of obestatin, but not by peptides corresponding to residues in the C-terminal region. Obestatin has been shown to activate receptor tyrosine kinase (RTK) pathways and induce signaling cascades that lead to the proliferation and differentiation of tumor cells.

A synthetic peptide for use as a blocking control in assays to test for specificity of ZNF92 antibody, catalog no. 20R-1238

FK-506 is an immunosuppressant that is produced by fermentation. It is used to prevent the rejection of transplanted organs and to treat a number of autoimmune diseases, including rheumatoid arthritis and multiple sclerosis. FK-506 binds to the IL-2 receptor on T-cells and inhibits their proliferation, thereby preventing activation of other immune cells. FK-506 has been shown to be effective in treating a number of diseases, including myocardial infarcts, coronary heart disease, and oral hypoglycaemic. The optimum concentration for this drug is not known, but it appears that higher concentrations are more beneficial in treating some conditions.

A synthetic peptide for use as a blocking control in assays to test for specificity of YPEL5 antibody, catalog no. 70R-9444

A synthetic peptide for use as a blocking control in assays to test for specificity of FTH1 antibody, catalog no. 70R-3512

A synthetic peptide for use as a blocking control in assays to test for specificity of BAG5 antibody, catalog no. 70R-10408

A synthetic peptide for use as a blocking control in assays to test for specificity of SAP30BP antibody, catalog no. 70R-8025

A synthetic peptide for use as a blocking control in assays to test for specificity of CASP8AP2 antibody, catalog no. 70R-8932

MOG(35-55) human corresponds to amino acids 35 to 55 of the human myelin oligodendrocyte glycoprotein (MOG). It can be used in multiple sclerosis research to induce experimental autoimmune encephalomyelitis (EAE) in mouse and rat models.

A synthetic peptide for use as a blocking control in assays to test for specificity of C1QA antibody, catalog no. 70R-9974

A synthetic peptide for use as a blocking control in assays to test for specificity of ZNF549 antibody, catalog no. 70R-8444

NY-ESO-1 (157-165) peptide – SLLMWITQC

A synthetic peptide for use as a blocking control in assays to test for specificity of DLAT antibody, catalog no. 70R-2503

A synthetic peptide for use as a blocking control in assays to test for specificity of Apof antibody, catalog no. 70R-8522

A synthetic peptide for use as a blocking control in assays to test for specificity of C6orf134 antibody, catalog no. 70R-1282

A synthetic peptide for use as a blocking control in assays to test for specificity of CAMK1G antibody, catalog no. 70R-4089

A synthetic peptide for use as a blocking control in assays to test for specificity of ARSA antibody, catalog no. 70R-5285

A synthetic peptide for use as a blocking control in assays to test for specificity of RNF165 antibody, catalog no. 70R-1152