Peptides

<p>pYEEI, a tetrapeptide containing phosphotyrosine, binds to the SrcSH2 domain with a dissociation constant (Kd) of 100 nM and an inhibitory concentration (IC50) of 6.5 μM. This compound plays a crucial role in cancer research.</p>

<p>G4 peptide (SIIGFEKL) is a modified OVA peptide (257-264) that binds to mouse MHC class I H-2Kb.</p>

<p>Lysipressin Acetate is an analog of vasopressin, a powerful vasopressin used to regulate blood pressure. Endogenous vasopressin in most mammalian species.</p>

<p>Suc-Leu-Leu-Val-Tyr-AMC is a fluorescent substrate for the 20S proteasome, other chymotrypsin-like proteases.</p>

<p>pGlu-Pro-Arg-MNA is a chromogenic substrate.</p>

<p>Endogenous neuropeptide S receptor agonist, EC50 = 9.4 nM; boosts wakefulness and activity, lowers anxiety in mice.</p>

<p>Body Protection Compound 157 (BPC 157) is a pentadecapeptide derived from BPC, identified in gastric juice, exhibiting diverse biological activities. At 2 µg/ml, BPC 157 enhances primary rat tendon fibroblast cell migration and F-actin formation. Furthermore, doses of 0.01 and 10 µg/kg, intraperitoneally (i.p.), mitigate paw swelling, bone erosion, and mononuclear cell infiltration in the joints of rats with rheumatoid arthritis induced by complete Freund's adjuvant (CFA). It also diminishes gastric ulcer size in rats caused by indomethacin, aspirin, or diclofenac at these doses. Additionally, BPC 157 reduces catalepsy duration and tremor severity in a mouse model of Parkinson's disease triggered by MPTP.</p>

<p>The HiBiT tag, a complementary peptide (VSGWRLFKKIS), exhibits high affinity for LgBiT. It is fused with the Gβ subunit of the receptor. The interaction between LgBiT and HiBiT facilitates the stabilization of ETR and G proteins. Additionally, HiBiT can be attached to target proteins (GFP) to quantify their transport to the cytosol.</p>

<p>Arginase (L-Arginine amidinase) is a key hydrolytic enzyme in the urea cycle, which hydrolyzes L-arginine into urea and L-ornithine.</p>

<p>C112 Peptide is a novel peptide.</p>

<p>JTP10-△-R9 TFA is a selective inhibitor of JNK2 peptide (IC50: 89 nM), exhibiting 10-fold selectivity for JNK2 over JNK1 and JNK3.</p>

<p>Locustapyrokinin II is a member of the FXPRL-amide peptide family isolated from Locusta migratoria.</p>

<p>p2Ca, peptide from alpha-ketoglutarate dehydrogenase, pairs with MHC-I protein Ld, recognized by CTL clone 2C.</p>

<p>Val-Lys(Boc)-PAB, an ADC linker, facilitates the synthesis of camptothecin peptide conjugates as antitumor agents and serves as a non-linear self-immolative linker to lessen the hydrophobicity of antibody-drug conjugates in cancer therapy.</p>

<p>Gersizangitide acetate is an inhibitor of angiogenesis.</p>

<p>APTSTAT3-9R acetate is a selective peptide binding STAT3 with antiproliferative and antitumor activity.</p>

<p>NPY: a 36-amino acid neuropeptide, affects vasoconstriction, memory, appetite, and circadian rhythm via G-protein receptors in nervous systems.</p>

<p>GRGDSPK acetate shows inhibitory activity against integrin-fibronectin binding and can be used in research on integrins in bone formation and resorption.</p>

<p>Catestatin acetate is a non-competitive antagonist of nAChR and inhibits catecholamine release.</p>

<p>Tanurmotide is a bioactive chemical.</p>