Peptides
Subcategories of "Peptides"
Found 29603 products of "Peptides"
Neurotensin
Neurotensin (NT) is involved in food absorption in the gut as well as acting as a neurotransmitter in the central nervous system (CNS). In the intestine, NT increases fatty acid translocation, in part by increasing intestinal blood flow. In the CNS, NT regulates pathways associated with ghrelin and leptin which mediate satiety and food ingestion. NT is also involved in the regulation of Luteinizing hormone (LH) and Prolactin release and also plays a role in hypotension- analgesia- gut contraction- vascular permeability- maintaining energy homeostasis- fat storage and metabolic disorders. Higher plasma pro-NT levels are associated with obesity and insulin resistance. NT is therefore a potential target for treating obesity-related diseases.NT is secreted from neuroendocrine cells in the small intestine upon fat intake and exerts its physiological actions by binding three NT receptor (NTR) types- NTR1, NTR2, and NTR3.NTR1 is highly expressed in various tumour cells including- small cell carcinoma/small cell lung cancer (SCLC)- meningiomas- astrocytomas- glioblastoma- pancreatic and colonic carcinoma, and breast and prostate cancers. NTR1 is therefore a possible target for novel cancer therapy.
Molecular weight:1,801 g/molH-VVAAVGDAVK^-OH
Peptide H-VVAAVGDAVK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-CLAVYQAGAR^-OH
Peptide H-CLAVYQAGAR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-FLNQTDETL^-OH
Peptide H-FLNQTDETL^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Fluor-ENPVVHFFKNIVTPR-OH
Peptide Fluor-ENPVVHFFKNIVTPR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-AVEEVSLR^-OH
Peptide H-AVEEVSLR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Histone H2A (1-20)
The histone H2A residues 1-20 are derived from histone 2A (H2A) which is one of the four core his-tones (H2A, H2B, H3 and H4) fundamental in compacting eukaryotic DNA into a structure known as the nucleosome. The nucleosome arises when 147 base pairs of DNA wrap around a H3-H4 tetramer and two H2A-H2B dimers, forming the histone octamer core.At the site of DNA entry on the outer nucleosome, the C-terminus of H2A is present and is able to interact with linker histones or other factors. This allows for variation and changes in nucleosome stability to occur. Furthermore Histone H2A has histone variants such as H2A.Z and H2A.X (which are present in all organisms) and these variants alter the organisation of the DNA.Due to histones containing a large number of lysine and arginine residues they have a positive net charge which interacts in an electrostatic manner with the negatively charged phosphate groups in DNA. The transcriptional activation or silencing of the chromatin is controlled by ATP-dependent chromatin remodelling factors and histone modifying enzymes which target histone proteins. Both processes function to alter to change the positioning of the nucleosome, allowing the DNA it to be either available to the transcription machinery or inaccessible.Molecular weight:2,086.2 g/molSARS-CoV-2 Antigen Peptide NCAP (TWLTYTGAIKLDDKDPNF)
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote ToolFormula:C97H144N22O30Molecular weight:2,098.43 g/molH-TKQTAR^^-OH
Peptide H-TKQTAR^^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
[5-FAM]-beta-Amyloid (1-15) Human
Fluorescein labelled amyloid β 1-15 (Aβ1-15 ). Aβ1-15 is one of many short Aβ species found in vivo and is formed by the cleavage of Aβ precursor protein by β- and alpha-secretase.Amyloid β-protein (Aβ) has been identified as the key subunit of the extracellular plaques found in the brains of patients with Alzheimer's disease (AD) and Down's syndrome (DS). Aβ has therefore been extensively studied as a potential target for treatment of AD.Aβ is formed from the cleavage of the large, transmembrane protein- APP (amyloid precursor protein). Cleavage of APP by β- and then γ-secretases results in the formation of Aβ. Aβ can aggregate to produce amyloid-β oligomers, which are thought to be highly neurotoxic. Over time Aβ can further aggregate to produce the characteristic senile plaques present in AD and DS. Aβ can be degraded by enzymes such as neprilysin, insulin degrading enzyme or endothelin converting enzyme. At physiological levels Aβ may be involved in controlling synaptic activity and neuronal survival.Fluorescein (FAM) is a hugely popular fluorescent tag due to its excellent fluorescence quantum yield and relatively high absorptivity as well as being highly water soluble.Molecular weight:2,183.8 g/molBDC2.5 mimotope 1040-51
BDC2.5 mimotope 1040-51 is a mimotope of BDC2.5 T cells which can recognise glutamic acid decarboxylase epitopes.Color and Shape:PowderMolecular weight:1,297.7 g/molH-IALILEPICCQERAA-OH
Peptide H-IALILEPICCQERAA-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Formula:C71H123N19O21S2Molecular weight:1,642.98 g/molSNRP70
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote ToolCMVpp65 - 136 (RHRQDALPGPCIAST)
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote ToolMolecular weight:1,621.9 g/molH-NTTGAL^TTR-OH
Peptide H-NTTGAL^TTR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-K^LVVVGAVG-OH
Peptide H-K^LVVVGAVG-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-IFYNQQSHYDGTTGK^-OH
Peptide H-IFYNQQSHYDGTTGK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-VLNDILSR^L-OH
Peptide H-VLNDILSR^L-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Jelleine I
Jelleines are a family of very small (8-9 amino acid residues long) host defence peptides (HDPs) isolated from the royal jelly of honey bees (Apis mellifera). Jelleines do not present any similarity with other HDPs from other honeybees and are produced by the workers and secreted into Royal Jelly and provide abroad-spectrum protection of the bee hive against microbial infections. The Jelleines are not considered cytolytic or directly involved with inflammatory effects.Jelleine-I may be produced by tryptic digestion of MRJP-1 (produced in the hypopharyngeal glands of the worker honeybee and secreted into the royal jelly), followed by an exoproteinase action on N-terminal of the tryptic fragment. Jelleine-I is only 953.24-Da and exhibits excellent anti-microbial activity against both gram positive and gram negative bacteria and fungi. Jelleine-I increases the production of cellular ROS and binds with genomic DNA, which may contribute to its anti-fungal activity.PLEASE NOTE that in several published articles the sequence of Jelleine-I has been printed as PFKLSLHL -NH2, due to a mistake in the original reference: Fontana et al., (2004). The correct sequence, is PFKISIHL-NH2.
Molecular weight:952.6 g/mol
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