Peptides
Subcategories of "Peptides"
Found 29634 products of "Peptides"
Histone H3 (32-38) K36Me2
Histone H3 (32-38) K36Me2 is derived from Histone 3 (H3) which is one of the four core histones (H2A, H2B, H3 and H4) fundamental in compacting eukaryotic DNA into the nucleosome. The nucleosome arises when 147 base pairs of DNA wrap around a H3-H4 tetramer and two H2A-H2B dimers, forming the histone octamer core. Both H4 and H3 are highly conserved and perform roles in binding to segments of DNA which enter and leave the nucleosome and in chromatin formation. Similar to the other core histone, H3 has a globular domain and a flexible N-terminal domain, 'histone tail' which can undergo modifications such as acetylation, methylation, phosphorylation and ubiquitination. Due to histones containing a large number of lysine and arginine residues they have a positive net charge which interacts in an electrostatic manner with the negatively charged phosphate groups in DNA. The transcriptional activation or silencing of the chromatin is controlled by ATP-dependent chromatin remodelling factors and histone modifying enzymes which target histone proteins. Both processes function to alter to change the positioning of the nucleosome, allowing the DNA it to be either available to the transcription machinery or inaccessible.The Histone H3 (32-38) lysine 36 has been dimethylated.
Molecular weight:713.4 g/molbeta-Amyloid (1-11) Biotin
β-Amyloid 1-11 (Aβ1-11) is one of many short Aβ species found in vivo and is formed by the cleavage of amyloid β precursor protein by β- and α-secretase. Amyloid β-protein (Aβ) has been identified as the key subunit of the extracellular plaques found in the brains of patients with Alzheimer disease (AD) and Down syndrome (DS). Aβ has therefore been extensively studied as a potential target for treatment of AD.Aβ is formed from the cleavage of the large, transmembrane protein- APP (amyloid precursor protein). Cleavage of APP by β- and then &γ--secretases results in the formation of Aβ. Aβ can aggregate to produce amyloid-β oligomers, which are thought to be highly neurotoxic. Over time Aβ can further aggregate to produce the characteristic senile plaques present in AD and DS. Aβ can be degraded by enzymes such as neprilysin, insulin degrading enzyme or endothelin converting enzyme. At physiological levels Aβ may be involved in controlling synaptic activity and neuronal survival.Biotin is C-terminally linked to the peptide via ethylenediaminefor convenient detection and purification. Alternative β-Amyloid fragments and labels are also available, please refer to our peptide catalogue for availability.Molecular weight:1,592.7 g/mol[5-FAM]-C7
Selective peptide ligand for FRalpha, demonstrating specific binding to FRalpha expression cells and tumour targeting ability in vivo. It contains 5-carboxyfluorescein (5-FAM), a widely used green fluorescent tag.Molecular weight:1,732.7 g/molAc-Gly-D-Arg-Gly-Asp-Ser-Pro-Ala-Ser-Ser-Lys-(Gly)4-Ser-D-Arg-(Leu)6-D-Arg-NH2
This synthetic peptide is a hydrophobic RGD Fibronectin Peptide which enhances cell attachment and adhesion. This is due to it containing the Arg-Gly-Asp (RGD) sequence, is a highly conserved integrin recognition sequence within fibronectin. As a result it can promote the adhesion of cells to fibronectin, a protein found in the extracellular matrix and also promotes adhesin of cells to collagen and laminin. One-Letter Formula: Ac-GrGDSPASSKGGGGSrLLLLLLr-AmideFormula:C98H174N34O30Purity:Min. 95%Molecular weight:2,308.69 g/molH-Phe-Ile-Arg-Val-Val-Met-Tyr-Glu-Gly-Lys-Lys-OH
H-Phe-Ile-Arg-Val-Val-Met-Tyr-Glu-Gly-Lys-Lys is a biologically active peptide that has been shown to have angiogenic and cardiovascular properties. It has also been demonstrated to inhibit thrombospondin, which is a protein that promotes the formation of blood clots. This peptide is a member of the group of peptides and biochemicals, which are molecules that regulate the processes in living organisms.Formula:C64H104N16O15SPurity:Min. 95%Molecular weight:1,369.7 g/molH-SSIMR^-OH
Peptide H-SSIMR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.For-Met-Leu-AMC
CAS:For-Met-Leu-AMC is a chemical compound that belongs to the group of speciality chemicals. It is a high quality, versatile building block that can be used as a reagent in organic synthesis and a reaction component in the synthesis of pharmaceuticals and other fine chemicals. For-Met-Leu-AMC is also a useful intermediate for the synthesis of complex compounds with potential for use as research chemicals or scaffolds for drug discovery.Formula:C22H29N3O5SPurity:Min. 98 Area-%Color and Shape:PowderMolecular weight:447.55 g/molAmyloid Beta-Protein (Human, 37-43) Antiserum
This product is an antiserum targeting amino acids 37-43 of the amyloid beta-protein which is a key component of extracellular plaques found in the brains of patients with Alzheimer’s disease (AD). It may also be involved in the pathogenesis of other neurodegenerative diseases such as Huntington’s disease and Parkinson’s disease. Targeting this protein may be key to drug discovery and the treatment of AD and other diseases this protein is associated with. Furthermore amyloid beta peptides located in the cerebrospinal fluid are well known biomarkers used to diagnose AD. Although AD is not yet curable, an early diagnosis can be useful in that patients can be treated to delay or improve symptoms. This product may also be used to detect amyloid beta protein in cell cultures, tissues, or fluids by immunohistochemistry or ELISA. It is suitable for use in life sciences, cell biology, and pharmacology studies.Purity:Min. 95%Fluor-QALPETGEE-OH
Peptide Fluor-QALPETGEE-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.SIVmac239 - 12
Custom research peptide; min purity 95%. For different specs please use the Peptide Quote ToolMolecular weight:1,618.8 g/molCyclo(Arg-Gly-Asp-D-Tyr-Lys)
CAS:Cyclo(Arg-Gly-Asp-D-Tyr-Lys) is a new synthetic peptide with anticancer activity. It has been shown to inhibit the growth of bladder cancer cells in vitro and in vivo, with no evidence of toxicity to normal bladder cells. Cyclo(Arg-Gly-Asp-D-Tyr-Lys) is a light sensitive molecule that can be delivered by an injection or as a pill. The peptide has been shown to have synergistic anticancer effects when combined with epirubicin, a chemotherapeutic drug used for the treatment of solid tumours, such as glioma and other cancers. Cyclo(Arg-Gly-Asp-D-Tyr-Lys) is also taken up by cells and causes DNA damage at the cellular level, leading to apoptosis.Formula:C27H41N9O8Purity:Min. 95%Molecular weight:619.68 g/molH-VSELTEEPDSGR^-OH
Peptide H-VSELTEEPDSGR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-CKSKKFRRPDIQYPD-NH2 000-000-404
Peptide H-CKSKKFRRPDIQYPD-NH2 000-000-404 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-Thr-Phe-Leu-Leu-Arg-Asn-Pro-Asn-Asp-Lys-NH2
This peptide is a PAR1-specific agonist that has been shown to produce cardioprotective effects in experimental models of myocardial infarction. It is a potent inhibitor of platelet aggregation and coagulation, and was found to be an effective antithrombotic agent in animal models. The peptide is also a potent vasodilator with potential for the treatment of hypertension.Formula:C54H89N17O15Purity:Min. 95%Molecular weight:1,215.67 g/molH-IEIYPTSLTK^-OH
Peptide H-IEIYPTSLTK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-ENATVAHLVGALR^-OH
Peptide H-ENATVAHLVGALR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.H-NSASFSTFK-OH
Peptide H-NSASFSTFK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Formula:C44H63N11O14Molecular weight:988.05 g/molH-ILSPFLPLL^-OH
Peptide H-ILSPFLPLL^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-EISTNIRQAGVQYSRADEEQ-OH
Peptide H-EISTNIRQAGVQYSRADEEQ-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Formula:C94H150N30O36Molecular weight:2,294.39 g/molH-RWKFGGFK^WR-OH
Peptide H-RWKFGGFK^WR-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
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