Peptides
Subcategories of "Peptides"
Found 29729 products of "Peptides"
Biotin gliadin-derived peptide
Biotin gliadin-derived peptides derived from Gliadin peptides, the component of wheat involved in the gastrointestinal symptoms of wheat allergy and Celiac Disease (CD). During wheat allergies histamines and leukotrienes are secreted due to gliadin peptide sequences cross-linking two IgE molecules on mast cells and basophils.The glutamine and proline rich peptides of which Gliadin is composed of are resistant to proteolysis during digestion, leaving them active in the gastrointestinal tract. Subsequently these are deamidated by tissue transglutaminase and can bind to HLA-DQ2 or DQ8. As a result in patients with the autoimmune disease CD, there is a Th-mediated inflammatory immune response against these gliadin peptides.Gliadin can exert additional effects on the intestinal microbiota and ileal barrier function. It has been found that gut microbiota members such as Bifidobacterium and lactobacillus have the ability to digest and inactivate gliadin peptides hence reducing their inflammatory effects in the gastrointestinal system.Here Biotin (B7) has been added. Biotin is a cofactor for several mammalian biotin-dependent carboxylases which are involved in processes such as gluconeogenesis, amino acid metabolism and fatty acid synthesis.Color and Shape:PowderMolecular weight:1,564.7 g/molH-SAFPTTINF^-OH
Peptide H-SAFPTTINF^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
ERAAP substrate Ep
Ep is a peptide-based fluorescent probe that can detect the intracellular amino-peptidase- ER aminopeptidase associated with antigen processing (ERAAP). ERAAP cleaves peptides presented by major histocompatibility complex (MHC) class I molecules to determine which are displayed on cell surfaces for T cell recognition. Down-regulation of ERAAP alters these cell surface peptides resulting in the cell being recognised as foreign. Therefore ERAAP is a potential target for increasing the immune response towards tumours. Down-regulation of ERAAP is also implicated in auto-immunity.Ep contains the fluorescent dye BODIPY and the fluorescent quencher dinitrophenyl (DNP), conjugated to the KK-SIINFECL peptide which is based on a known ERAAP-substrate. Ep initially has low fluorescence due to the proximity of the DNP quencher, however after ERAAP cleaves the N-terminal amino acid of Ep and releases the DNP quencher, a dramatic 20 fold increase in fluorescence is seen.Ep can detect ERAAP in cells in a highly sensitive and specific manner. Ep can detect ERAAP activity in live cells and in high-throughput-screens (HTS), and can compete with endogenous cellular substrates for ERAAP.Molecular weight:1,773.7 g/molH-ASNTAEVFFDGVR^-OH
Peptide H-ASNTAEVFFDGVR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.Biotin-beta-Amyloid (1-15) human
β-Amyloid 1-15 (Aβ1-15) is one of many short Aβ species found in vivo and is formed by the cleavage of amyloid β precursor protein by β- and alpha-secretase.Amyloid β-protein (Aβ) has been identified as the key subunit of the extracellular plaques found in the brains of patients with Alzheimer's disease (AD) and Down's syndrome (DS). Aβ has therefore been extensively studied as a potential target for treatment of AD.Aβ is formed from the cleavage of the large, transmembrane protein- APP (amyloid precursor protein). Cleavage of APP by β- and then γ-secretases results in the formation of Aβ. Aβ can aggregate to produce amyloid-β oligomers, which are thought to be highly neurotoxic. Over time Aβ can further aggregate to produce the characteristic senile plaques present in AD and DS. Aβ can be degraded by enzymes such as neprilysin, insulin degrading enzyme or endothelin converting enzyme. At physiological levels Aβ may be involved in controlling synaptic activity and neuronal survival.This peptide contains a covalently attached N-Terminal biotin tag for convenient detection and purification.Molecular weight:2,052.8 g/molrec IL-3 (human)
CAS:Please enquire for more information about rec IL-3 (human) including the price, delivery time and more detailed product information at the technical inquiry form on this pagePurity:Min. 95%Spexin 2 (53-70) Human, Mouse, Rat
Spexin is a neuropeptide encoded by SPX genes, and homologs have been found amongst many vertebrates. The SPX genes encode a preprohormone that leads to the mature hormone spexin, which is highly conserved amongst higher vertebrates. Another form, SPX2, has been identified and named spexin 2. Both sequences of spexin and spexin 2 are highly conserved, suggesting they each play vital roles.Like spexin, spexin 2 is widely expressed in various tissues. This is an amidated spexin-2 (53-70) peptide showing similar biological function to its non- amidated version. Spexin-2, when administered to rats, decreases heart rate and increases urine flow rate. Intraventricular NPQ(53-70) delivery also causes antinociceptive activity in mice's warm water tail withdrawal assay.Molecular weight:2,158.1 g/molH-YEALLLGGLPQEGLAR^-OH
Peptide H-YEALLLGGLPQEGLAR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-EDSQCVIGLYQPPLQVY-NH2
Peptide H-EDSQCVIGLYQPPLQVY-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
IL 4 Human
IL 4 is a cytokine that is responsible for the proliferation and activation of B cells, T cells, macrophages and other immune cells. IL 4 binds to the high affinity receptor IL-4Rα. It also activates the membrane bound IL-4Rβ. The IL-4Rα is a heterodimer consisting of an alpha chain, which is shared by all members of the type II cytokine receptor family, and the common beta chain shared by all type I cytokines receptors. IL-4 has been shown to be effective in inhibiting tumor growth in vivo and in vitro.
Purity:>98% By Sds-Page And Rp-Hplc.H-SAEGLDASASLR^-OH
Peptide H-SAEGLDASASLR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.SOD1 (147-153) human
The SOD1 homodimer forms a β-barrel and contains an intramolecular disulphide bond and a binuclear Cu/Zn site in each subunit. This Cu/Zn site holds a copper and zinc ion and is responsible for catalysing the disproportionation of ROS, namely superoxide to hydrogen peroxide and dioxygen. In binding to copper and zinc ions, SOD1 is one of three superoxide dismutases responsible for destroying free superoxide radicals.The clinical relevance of SOD1 is related to its function in regulating ROS in the mitochondria of cells. Most notably, SOD1 is a crucial enzyme involved in ROS release during oxidative stress by ischemia-reperfusion injury, specifically in the myocardium as part of ischemic heart disease. During ischemia reperfusion, ROS release substantially contribute to the cell damage and death via a direct effect on the cell as well as via apoptotic signals. SOD1 is known to have a capacity to limit the detrimental effects of ROS. As such, SOD1 is important for its cardioprotective effects.Molecular weight:656.4 g/molH-QKSDDDYEDYASNKTC-NH2
Peptide H-QKSDDDYEDYASNKTC-NH2 is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-LLVYTILPDGEVVGDSAK^-OH
Peptide H-LLVYTILPDGEVVGDSAK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
H-WLQGSQELPR^-OH
Peptide H-WLQGSQELPR^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Glutaryl-Phe-Ala-Ala-Phe-AMC TFA salt
CAS:Glutaryl-Phe-Ala-Ala-Phe-AMC TFA salt is a fine chemical, useful building block, and research chemical. It is a high quality, versatile scaffold that can be used as a reaction component or intermediate in the synthesis of complex compounds.Formula:C39H43N5O9•C2HF3O2Purity:Min. 95 Area-%Color and Shape:PowderMolecular weight:839.81 g/mol[Azhx]-[Lys(Mca)]-P11-8
The P11-family of peptides comprises over 20 different peptides which self-assemble into β-sheet structures to form self-supporting isotropic hydrogels under physiological conditions (pH 7.4, 140 mM NaCl). Self-assembling peptides of the P11-family undergo one-dimensional self-assembly, forming single molecule thick, micrometer-long β-sheet nanotapes. Further assembly results in the nanotapes stacking in pairs to form ribbons which further assemble to form fibrils, then pairs of fibrils can entwine to form fibres. Such self-assembling peptides are important biomaterials and may be useful for the development of novel biomaterials for tissue engineering scaffolds and dental enamel remineralisation.Molecular weight:2,151.1 g/molH-HSVVVPYEPPEAGSEYTTIHYK^-OH
Peptide H-HSVVVPYEPPEAGSEYTTIHYK^-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
Ac-DRVYIHPF-OH
Angiotensin II plays an essential role in the maintenance of blood pressure and blood volume. It is a peptide hormone that causes vasoconstriction, a sensation of thirst, and stimulation of the adrenal cortex and aldosterone.
Derived from the cleavage of angiotensin I by the angiotensin converting enzyme, angiotensin II is involved in the renin-angiotensin system (RAS).
Angiotensin II is the subject of much scientific research and is already the target of many anti-hypertensive drugs (ACE inhibitors, ARBs or AT1 receptor antagonists).H-VVSVLTVTHQDWL^NGK-OH
Peptide H-VVSVLTVTHQDWL^NGK-OH is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice.
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