Peptides

A synthetic peptide for use as a blocking control in assays to test for specificity of ZFP287 antibody, catalog no. 20R-1161

Muscle-type nAChRs blocker

A synthetic peptide for use as a blocking control in assays to test for specificity of FSTL5 antibody, catalog no. 70R-1991

Universal Major Histocompatibility Complex (MHC) H2 I-Ab epitope for CD4+ T-cell recruitment and activation
SB-PEPTIDE offers I-Ab restricted PADRE peptide ak(Cha)VAAWTLKAAa-Ahx-C.
Pan DR-binding epitope (PADRE) is a universal synthetic peptide binding Major Histocompatibility Complex (MHC)-II receptors, of which H2 complex (mouse MHC), present on specific immune cells. 4 class II loci exist in the region I of the H2 complex gene (see image below), known as Aa & Ea loci (α encoded) and Ab & Eb loci (β encoded), that are similar to the DR, DP and DQ loci of the Human Leukocyte Antigen (HLA) complex.
I-Ab restricted PADRE peptide interacts specifically with mouse H2-I-Ab receptors that activate antigen specific CD4+ T-cells in the same way as PADRE peptide’s interaction with HLA-DR receptors. This feature places I-Ab restricted PADRE as promising adjuvant for immunotherapeutic vaccines against chronicle diseases such as infections, Alzheimer or cancer. Similarly to the original PADRE peptide, the restricted version also acts as a Toll-like receptor (TLR) agonist and was described as alternative carrier, such as KLH/BSA or OVA, for prophylaxis and therapeutic vaccines. An aminocaproic acid (Ahx) linker, attached to an additional C-terminal Cysteine, was added to the sequence to allow both the peptide and its loading to interact independently and freely with molecules exposed to them. This modification is used for the loading of antigenic determinants in solution in order to enhance the immune response against a specific antigen (AG).

A synthetic peptide for use as a blocking control in assays to test for specificity of ABHD5 antibody, catalog no. 70R-1266

A synthetic peptide for use as a blocking control in assays to test for specificity of CHERP antibody, catalog no. 70R-5262

Z-Val-Val-Arg-AMC is a synthetic peptide that activates the glycine receptor. It has been shown to inhibit ion channel function in a rat model of epilepsy, and also to block the binding of an antibody against the glycine receptor. The peptide was synthesized by coupling L-valine, L-valylglycine, and L-arginine with methyl 2-(4'-methylaminophenyl) acetate. Z-Val-Val-Arg-AMC is a high purity product that has been shown to be useful in cell biology research as a tool for studying ligand/receptor interactions.

A synthetic peptide for use as a blocking control in assays to test for specificity of ARV1 antibody, catalog no. 70R-6453

A synthetic peptide for use as a blocking control in assays to test for specificity of TIPRL antibody, catalog no. 70R-10411

A synthetic peptide for use as a blocking control in assays to test for specificity of ANKRD42 antibody, catalog no. 70R-4812

A synthetic peptide for use as a blocking control in assays to test for specificity of RNF212 antibody, catalog no. 70R-2823

A synthetic peptide for use as a blocking control in assays to test for specificity of CDKL2 antibody, catalog no. 70R-3300

A synthetic peptide for use as a blocking control in assays to test for specificity of HORMAD2 antibody, catalog no. 70R-1993

A synthetic peptide for use as a blocking control in assays to test for specificity of RBM26 antibody, catalog no. 70R-4963

MAL-dPEG®11-Lipoamide is a PEG molecule conjugated with a lipid moiety. MAL-dPEG®11-Lipoamide, conjugated to this lipid constituent, is very important especially in drug delivery and vaccine development as it helps improve the stability and circulation time of lipid nanoparticles (LNPs) and liposomes.

PACAP is a peptide that belongs to the class of activators. It is used as a research tool for its ability to activate ion channels in mammalian cells. PACAP interacts with receptors and can be found in both the central nervous system and peripheral tissues. The receptor for PACAP, known as the PAC1 receptor, is coupled to G-proteins and regulates adenylate cyclase activity. PACAP has been shown to inhibit cell proliferation and promote apoptosis in various types of cancer cells.
PACAP also stimulates the release of oxytocin from neurohypophysis cells, which may lead to its use as a treatment for autism spectrum disorders or depression.

A synthetic peptide for use as a blocking control in assays to test for specificity of Klkb1 antibody, catalog no. 70R-8632

A synthetic peptide for use as a blocking control in assays to test for specificity of LANCL2 antibody, catalog no. 70R-2713

A synthetic peptide for use as a blocking control in assays to test for specificity of C9orf4 antibody, catalog no. 70R-6869