Angiogénesis
Los inhibidores de la angiogénesis son compuestos que interfieren con la formación de nuevos vasos sanguíneos, un proceso crucial en el crecimiento y la metástasis del cáncer. Al inhibir la angiogénesis, estos compuestos pueden restringir el suministro de sangre a los tumores, ralentizando o deteniendo su crecimiento. Los inhibidores de la angiogénesis son esenciales en la investigación del cáncer y en el desarrollo terapéutico, proporcionando información sobre los mecanismos de progresión tumoral y ofreciendo posibles tratamientos para el cáncer y otras enfermedades relacionadas con la angiogénesis. En CymitQuimica, ofrecemos una amplia gama de inhibidores de la angiogénesis de alta calidad para apoyar su investigación en oncología y biología vascular.
Subcategorías de "Angiogénesis"
- BTK(146 productos)
- Bcr-Abl(102 productos)
- EGFR(572 productos)
- FAK(72 productos)
- FLT(92 productos)
- Receptor del factor de crecimiento de fibroblastos (FGFR)(169 productos)
- JAK(245 productos)
- PDGFR(126 productos)
- RAAS(87 productos)
- Src(79 productos)
- Syk(37 productos)
- Trombina(47 productos)
- VDA(2 productos)
- VEGFR(268 productos)
Mostrar 6 subcategorías más
Se han encontrado 1431 productos de "Angiogénesis"
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AZ 12799734
CAS:<p>AZ 12799734 is an orally active, selective and potent dual inhibitor of TGFBR1 and ALK5 with inhibitory effects on BMP and TGFβ for the study of tumours.</p>Fórmula:C18H18N4O3SPureza:98.23%Forma y color:SolidPeso molecular:370.43Cavutilide
CAS:<p>Cavutilide has antiarrhythmic activity, inhibits hERG K(+) channels, and can be used to study heart failure and persistent atrial fibrillation.</p>Fórmula:C22H26FN3O3Pureza:99.82% - 99.85%Forma y color:SolidPeso molecular:399.458SB 203580 hydrochloride
CAS:<p>SB 203580 hydrochloride (Adezmapimod hydrochloride) is a p38 MAPK inhibitor that induces mitochondrial autophagy and cytosolic autophagy.</p>Fórmula:C21H17ClFN3OSPureza:97.79%Forma y color:SolidPeso molecular:413.9SB-505124 hydrochloride
CAS:<p>SB-505124 hydrochloride (SB505124 hydrochloride) is a TGF-β type I receptor (ALK4, ALK5, ALK7) inhibitor for the study of colorectal cancer.</p>Fórmula:C20H22ClN3O2Pureza:98.71%Forma y color:SolidPeso molecular:371.86CCT241161
CAS:<p>CCT241161: oral pan-RAF inhibitor; IC50s: LCK (3 nM), CRAF (6), SRC (10), V600E-BRAF (15), BRAF (30); fights BRAF/NRAS melanomas, anti-proliferative.</p>Fórmula:C28H27N7O3SPureza:99.76% - 99.77%Forma y color:SolidPeso molecular:541.62α-Eudesmol
CAS:<p>Applications α-Eudesmol is an isomer of β-Eudesmol (E938600), a sesquiterpenoid known to induce neurite outgrowth. β-Eudesmol exhibits antiangiogenic activity.<br>References Obara, Y. et al.: J. Pharmacol. Exp . Ther., 30, 803 (2011); Tsuneki, H. et al.: Eur. J. Pharmacol., 512, 105 (2005);<br></p>Fórmula:C15H26OForma y color:White To Off-WhitePeso molecular:222.37Donafenib
CAS:<p>Donafenib(Bay 43-9006 (D3)) is a deuterium-labeled Sorafenib which is a multikinase inhibitor(IC50s: 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3,</p>Fórmula:C21H13ClD3F3N4O3Pureza:99.88%Forma y color:SolidPeso molecular:467.84rac-Clopidogrel Hydrochloride
CAS:<p>Impurity Clopidogrel Impurity B; Clopidogrel USP B; Clopidogrel USP Related Compound B<br>Applications Clopidogrel Related Compound B (Clopidogrel Impurity B; Clopidogrel USP B; Clopidogrel USP Related Compound B) is a tetrahydrothienopyridine as inhibitor of angiogenesis.<br>References Maffrand, J. P., et al.: Eur. J. Med. Chem., 9, 483 (1974), Thebault, J.J., et al.: Clin. Pharmacol. Ther., 18, 485 (1975),<br></p>Fórmula:C16H16ClNO2S·ClHForma y color:NeatPeso molecular:358.28Itacnosertib
CAS:<p>Itacnosertib (TP-0184) is an orally available ACRV1 (ALK-2), FLT3 and JAK2 inhibitor that inhibits the growth of tumor cells,antitumor and antileukemic.</p>Fórmula:C26H28N8OPureza:99.38%Forma y color:SolidPeso molecular:468.55Glycerol 1-Monobutyrate (Technical Grade)
CAS:<p>Applications Glycerol 1-Monobutyrate functions as a key regulatory molecule in angiogenic process.<br>References Dobson, D. E., et al.: Cell (Cambridge, MA, U. S.), 61, 223 (1990)<br></p>Fórmula:C7H14O4Forma y color:NeatPeso molecular:162.18Syk Inhibitor II
CAS:<p>Syk inhibitor II, a cell-permeable, ATP-competitive, pyrimidine-carboxamide compound, selectively and reversibly inhibits Syk (IC50 = 41 nM).</p>Fórmula:C14H15F3N6OPureza:97.63%Forma y color:SolidPeso molecular:340.3BIBF 1202
CAS:<p>BIBF 1202 is a VEGFR2 kinase inhibitor (IC50 = 62 nM).</p>Fórmula:C30H31N5O4Pureza:98.04%Forma y color:SolidPeso molecular:525.6Canertinib dihydrochloride
CAS:<p>Canertinib dihydrochloride (PD-183805 dihydrochloride) is the hydrochloride salt of an orally bio-available quinazoline with potential antineoplastic and</p>Fórmula:C24H27Cl3FN5O3Pureza:99.13% - >99.99%Forma y color:SolidPeso molecular:558.86BMS-690514
CAS:<p>BMS-690514 is a potent and orally active inhibitor of EGFR and VEGFR. It has IC50s of 5, 20 and 60 nM for EGFR, HER 2 and HER 4, respectively.</p>Fórmula:C19H24N6O2Pureza:99.08%Forma y color:SolidPeso molecular:368.43(5E)-5-(4-Hydroxybenzylidene)-1,3-thiazolidine-2,4-dione
CAS:Producto controlado<p>Applications 5-[(4-Hydroxyphenyl)methylene]-2,4-thiazolidinedione is a 5-Benzylidene-2,4-thiazolidenedione derivative designed as inhibitors of angiogenesis targeting VEGFR-2. Also, it is an intermediate used in the synthesis of MSDC 0602 (M755420), which is an analogue of thiazolidinediones, exhibits low affinity for binding and activation of peroxisome proliferator-activated receptor γ (PPARγ). Thiazolidinediones are effective insulin-sensitizing drugs for treating various metabolic and inflammatory diseases.<br>References Bhanushali, U., et al.: Bioorg. Chem., 67, 139-147 (2016); Chen, Z., et al.: J. Biol. Chem. 287, 23537 (2012); Fukunaga, T., et al.: J. Bone Miner. Res., 30, 508 (2015)<br></p>Fórmula:C10H7NO3SForma y color:NeatPeso molecular:221.23Methyl 6-[[[(2-Chloroethyl)amino]carbonyl]amino]-6-deoxy-α-D-glucopyranoside
CAS:Producto controladoFórmula:C10H19ClN2O6Forma y color:NeatPeso molecular:298.72Solrikitug
CAS:<p>Solrikitug,Anti-CRLF2 humanized IgG1κ monoclonal antibody.</p>Pureza:95%Forma y color:LiquidSerclutamab
CAS:<p>Serclutamab, a humanized chimeric monoclonal antibody of the IgG1-κ isotype, selectively targets the epidermal growth factor receptor (EGFR).</p>Pureza:98%Forma y color:LiquidVanucizumab
CAS:<p>Vanucizumab is a bispecific humanised monoclonal antibody that simultaneously inhibits the receptor interactions of VEGF-A and Angiopoietin-2 (Ang-2)</p>Pureza:95%Forma y color:LiquidZalutumumab
CAS:<p>Zalutumumab is a high-affinity fully human monoclonal antibody ,the extracellular domain of the EGFR squamous cell carcinoma of the head and neck (SCCHN).</p>Pureza:95%Forma y color:LiquidFutuximab
CAS:<p>Futuximab, a chimeric monoclonal antibody, targets distinct epitopes on the epidermal growth factor receptor (EGFR), exhibiting antineoplastic activity [1].</p>Pureza:95% - 95%Forma y color:LiquidDilpacimab
CAS:<p>Dilpacimab (ABT165) is a dual-variable antibody that targets DLL4 and VEGF pathways, showing potential in cancer research by blocking angiogenesis and Notch.</p>Pureza:95% - 95%Forma y color:LiquidAnti-Mouse VEGFR-2 Antibody (DC101)
<p>Anti-Mouse VEGFR-2 Antibody (DC101) is a rat-derived monoclonal antibody against mouse VEGFR2/KDR/Flk-1, serving as a mouse analogue of ramucirumab.</p>Pureza:99%Forma y color:Odour LiquidImgatuzumab
CAS:<p>Imgatuzumab (RG 7160) is a humanized anti-EGFR monoclonal antibody and immunomodulator for cancer research.</p>Forma y color:LiquidPeso molecular:145.0 (kDa)Tovetumab
CAS:<p>Tovetumab (MEDI-575) is an anti-PDGFRα mAb inhibiting its signaling, in trials for glioblastoma and NSCLC.</p>Pureza:95%Forma y color:LiquidIvonescimab
CAS:<p>Ivonescimab (AK112) is a PD-1/VEGF bispecific antibody with cancer immunotherapy and anti-angiogenic effects, NSCLC).</p>Pureza:95% - 95%Forma y color:LiquidBafisontamab
CAS:<p>Bafisontamab (EMB-01) is a bispecific antibody that targets EGFR and cMET, displaying antitumor activity [1].</p>Forma y color:LiquidIzalontamab
CAS:<p>Izalontamab (SI-B001) is a bispecific EGFR/HER3 monoclonal antibody that binds to both EGFR×EGFR homodimers and EGFR×HER3 heterodimers.</p>Pureza:95%+ - 95%+Forma y color:LiquidAnbenitamab
CAS:<p>Anbenitamab (KN-026) is a bispecific HER2 antibody for metastatic breast cancer research, blocking HER2 pathways and mediating ADCC.</p>Forma y color:LiquidFaricimab
CAS:<p>Faricimab,Bispecific antibody targeting Ang-2/VEGF-A. Prevents retinal I/R injury. Improves vision in w-AMD, DME, RVO.</p>Pureza:95% - 95%Forma y color:LiquidFidasimtamab
CAS:<p>Fidasimtamab, a recombinant human IgG1 bispecific antibody, targets both HER2 and PD-1, bridging T cells and tumor cells to modulate immune responses.</p>Pureza:95% - 95%Forma y color:LiquidBecotatug
CAS:<p>Becotatug (JMT-101) is an IgG1 antibody that targets EGFR and can be conjugated to Afatinib and Osimertinib, functioning as a synthetic antibody-drug conjugate</p>Pureza:95% - 95%Forma y color:LiquidPonezumab
CAS:<p>Ponezumab (PF-04360365), a humanized IgG2 antibody, lowers Aβ in the CNS & boosts mice memory. Used in Alzheimer's research.</p>Forma y color:LiquidTarcocimab
CAS:<p>Tarcocimab (OG1953) is a humanized IgG1 monoclonal antibody targeting VEGFA, researched for RVO and wet AMD.</p>Forma y color:LiquidElgemtumab
CAS:<p>Elgemtumab (LJM716) is a fully humanised monoclonal antibody targeting HER3/ERBB3, acting as an antagonist to block HER3/Akt phosphorylation antitumour.</p>Pureza:95%Forma y color:LiquidDepatuxizumab
CAS:<p>Depatuxizumab is a humanised monoclonal antibody targeting EGFR with blood-brain barrier (BBB) permeability, inhibit tumor growth,GBM,SCCHN.</p>Pureza:95%Forma y color:LiquidZanidatamab
CAS:<p>Zanidatamab (ZW25) is a bispecific, humanized monoclonal antibody that targets two distinct epitopes (ECD2 and ECD4) of the HER2 receptor, exhibiting anti-tumor</p>Forma y color:LiquidIbrutinib-d5
CAS:<p>Ibrutinib D5 is a deuterium-labeled Ibrutinib. Ibrutinib is an irreversible Btk inhibitor.</p>Fórmula:C25H24N6O2Pureza:98%Forma y color:SolidPeso molecular:445.53Dasatinib-d8
CAS:<p>Dasatinib D8 is deuterium-labeled dasatinib. Dasatinib is a dual Bcr-Abl and Src family tyrosine kinase inhibitor.</p>Fórmula:C22H26ClN7O2SPureza:98%Forma y color:SolidPeso molecular:496.06IGF-1R modulator 1
CAS:<p>IGF-1Rmodulator 1 (Example 5) is an IGF-1R modulator featuring an EC50 of 0.29 μM (FGFR1), 0.25 μM (IGF1R), 0.34 μM (TrkA), and 0.39 μM (TrkB). This compound is useful in research on diseases characterized by impaired signaling of neurotrophic and/or other trophic factors, such as Alzheimer's disease.</p>Fórmula:C22H17N3O4Forma y color:SolidPeso molecular:387.39AD1058
CAS:<p>AD1058 is a selective ATR inhibitor that crosses the blood-brain barrier with in vivo anticancer activity, used in the study of brain and CNS metastasis.</p>Fórmula:C19H20N6O3SPureza:98.24%Forma y color:SolidPeso molecular:412.47EGFR-IN-109
CAS:<p>EGFR-IN-109 (compound 4), an EGFR inhibitor, displays IC 50 values of 25.8 nM for EGFR WT and 182.3 nM for EGFR T790M. This compound halts the growth of cancer cells at the G2/M phase and triggers both early and late apoptosis. It is applicable in cancer research [1].</p>Fórmula:C12H16N4OSForma y color:SolidPeso molecular:264.35HVH-2930
CAS:<p>HVH-2930 is an inhibitor of Heat Shock Protein 90 (HSP90). It suppresses the cell viability of BT474 (Trastuzumab sensitive) and JIMT-1 (Trastuzumab resistant) by downregulating HSP90 client proteins such as HER2, p-HER2, AKT, p-AKT, cyclin D1, and survivin, with IC50 values of 6.86 μM and 4.42 μM, respectively. Additionally, HVH-2930 demonstrates antitumor efficacy in a mouse model and exhibits favorable pharmacokinetic properties in vivo.</p>Fórmula:C29H36N4O3Forma y color:SolidPeso molecular:488.62(3S,4S)-Tofacitinib
CAS:<p>(3S,4S)-Tofacitinib, a less active enantiomer of tofacitinib, is a Janus kinases inhibitor.</p>Fórmula:C16H20N6OPureza:98%Forma y color:SolidPeso molecular:312.37MAPK-IN-2
<p>MAPK-IN-2 (compound 3h) is an efficacious MAPK inhibitor with antineoplastic properties that significantly hinders proliferation across various cancer cell</p>Fórmula:C20H11Cl2N3OPureza:98%Forma y color:SolidPeso molecular:380.23Erlotinib mesylate
CAS:<p>Erlotinib: reversible inhibitor binding to ATP site of epidermal growth factor receptor.</p>Fórmula:C23H27N3O7SPureza:98%Forma y color:SolidPeso molecular:489.54GZD856 formic
CAS:<p>GZD856 formic inhibits PDGFRα/β (IC50: 68.6, 136.6 nM) & Bcr-Abl (IC50: 19.9, 15.4 nM), with antitumor properties.</p>Fórmula:C30H29F3N6O3Forma y color:SolidPeso molecular:578.58ZM39923
CAS:<p>ZM39923 is a JAK3 inhibitor (pIC50: 7.1). ZM39923 also effectively inhibits tissue transglutaminase (IC50: 10 nM).</p>Fórmula:C23H25NOPureza:98%Forma y color:SolidPeso molecular:331.45ALK5-IN-79
CAS:<p>ALK5-IN-79 (compound 57), an ALK inhibitor, exhibits anticancer activity by inhibiting the TGF-β1/SMAD signaling pathway. It effectively reduces the production of extracellular matrix (ECM) and collagen deposition. Moreover, ALK5-IN-79 demonstrates satisfactory pharmacokinetic (PK) properties and favorable in vivo tolerance.</p>Fórmula:C23H27N7OForma y color:SolidPeso molecular:417.51EGFR-IN-117
CAS:<p>EGFR-IN-117 (Compound 8h) exhibits inhibitory activity against EGFR mutations, specifically targeting the tumor environment and inducing apoptosis in cancer cells. This compound effectively inhibits the proliferation of H1975, PC-9, and mutant EGFR cells including BaF3-EGFRL858R/T790M/C797S and BaF3–C797S/Del19/T790M, with IC50 values of 13 nM, 19 nM, 1.2 nM, and 1.3 nM respectively. Additionally, EGFR-IN-117 demonstrates anti-tumor activity in mouse models.</p>Fórmula:C25H30BrN7O2SForma y color:SolidPeso molecular:572.52Tyrphostin AG 1478
CAS:Producto controlado<p>Applications Tyrphostin AG 1478 is a potent and selective inhibitor of EGFR.<br></p>Fórmula:C16H14ClN3O2Forma y color:NeatPeso molecular:315.754-Fmoc-3(R)-morpholinecarboxylic Acid
CAS:Producto controlado<p>Applications 4-Fmoc-3(R)-morpholinecarboxylic Acid is used to prepare 125I-labeled morpholine-containing RGD ligand of αvβ3 integrin as angiogenesis imaging probe.<br>References Bianchini, F., et al.: J. Med. Chem., 55, 5024 (2012)<br></p>Fórmula:C20H19NO5Forma y color:NeatPeso molecular:353.37N-(4-Fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)-2-pyrimidinamine
CAS:Producto controladoFórmula:C20H16FN5O3Forma y color:Light Yellow To YellowPeso molecular:393.372-Chloro-N-[4-(1-cyanocyclopentyl)phenyl]-3-pyridinecarboxamide
CAS:Producto controlado<p>Applications 2-Chloro-N-[4-(1-cyanocyclopentyl)phenyl]-3-pyridinecarboxamide is an intermediate Apatinib 25-N-Oxide (A726160), a metabolite of the antiangiogenic agent and selective VEGFR2 inhibitor Apatinib (A726150).<br></p>Fórmula:C18H16ClN3OForma y color:NeatPeso molecular:325.79Tyrphostin AG 112
CAS:Producto controlado<p>Applications Tyrphostin AG 112 is an EGFR inhibitor.<br></p>Fórmula:C13H8N4OForma y color:NeatPeso molecular:236.23Des-(4-(dimethylamino)-2-butenoyl)-Neratinib
CAS:Producto controlado<p>Applications 6-Amino-4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-7-ethoxyquinoline-3-carbonitrile, is used in the synthetic preparation of aminopropanamides which is used in irreversible inhibition of epidermal growth factor receptor (EGFR) for potential use in cancer therapy.<br>References Carmi, C., et al.: J. Med. Chem., 55, 2251 (2012)<br></p>Fórmula:C24H20ClN5O2Forma y color:NeatPeso molecular:445.9LB 42708
CAS:Producto controlado<p>Applications LB 42708 is a selective nonpeptidic Farnesyltransferase (FTase) inhibitor.LB42708 suppresses tumor growth and tumor angiogenesis in both xenograft tumor models of Ras-mutated HCT116 cells and its wild-type Caco-2 cells, indicating its potential application in the treatment of both Ras-mutated and wild type tumors.<br>References Kim, C., et. al.: Mol. Pharmacol., 78, 142 (2010)<br></p>Fórmula:C30H27BrN4O2Forma y color:NeatPeso molecular:555.46Pulsatilla Saponin D (90%)
CAS:Producto controlado<p>Applications Pulsatilla Saponin D shows antiangiogenic and antitumor activity.<br>References Sang-Won, H. et al.: Carcinogen., 34, 2156 (2013);<br></p>Fórmula:C47H76O17Pureza:90%Forma y color:NeatPeso molecular:913.1Dehydrodivanillin (~90%, contains up to 10% unknown inorganics)
CAS:Fórmula:C16H14O6Forma y color:NeatPeso molecular:302.279Atrasentan
CAS:Producto controlado<p>Applications Atrasentan is a selective antagonist of the endothelin-A (ETA) receptor and binds selectively to the ETA receptor, which may result in inhibition of endothelin-induced angiogenesis and tumor cell proliferation.<br>References Bax, W., et al.: Trends Pharmacol. Sci., 15, 379 (1994); Winn, M., et al.: J. Med. Chem., 39, 1039 (1996); Wu-Wong, J., et al.: J. Pharmacol. Exp. Ther., 281, 791 (1997);<br></p>Fórmula:C29H38N2O6Forma y color:Off-WhitePeso molecular:510.622,3-Naphthalic Anhydride
CAS:Producto controlado<p>Stability Moisture Sensitive<br>Applications 2,3-Naphthalic anhydride is used as a reagent to synthesize analogues of Thalidomide (T338850), an inhibitor of tumour necrosis factor that was once abandoned because it caused birth defects, but is currently used as an inhibitor of angiogenesis in patients with multiple myeloma.<br>References D’Amato, R., et al.: Proc. Nat. Acad. Sci., 91, 4082 (1994); Ehrenpreis, E., et al.: Gastroenterology, 117, 1271 (1999); Parma, T., et al.: Nat. Med., 5, 582 (1999); Singhal, S., et al.: New Engl. J. Med., 341, 1565 (1999)<br></p>Fórmula:C12H6O3Forma y color:NeatPeso molecular:198.17Bucillamine
CAS:<p>Bucillamine (DE019) protects against Ischemia/reperfusion injury in high-risk organ transplants and inhibits the production of VEGF.</p>Fórmula:C7H13NO3S2Pureza:99.47%Forma y color:SolidPeso molecular:223.31E3330
CAS:<p>E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.</p>Fórmula:C21H30O6Pureza:99.52%Forma y color:SolidPeso molecular:378.46TUL01101
CAS:<p>TUL01101, a selective oral JAK1 inhibitor (IC50: 3 nM), also targets JAK2, JAK3, TYK2; for rheumatoid arthritis research.</p>Fórmula:C22H25F2N5O2Forma y color:SolidPeso molecular:429.46BGB659
CAS:<p>BGB659 is effective inhibitor of RAF.</p>Fórmula:C29H29F3N4O3Pureza:98%Forma y color:SolidPeso molecular:538.56KRCA-0713
CAS:<p>KRCA-0713 is a ALK inhibitor.</p>Fórmula:C26H32ClN5O3SPureza:98%Forma y color:SolidPeso molecular:530.08EGFR-IN-53
CAS:<p>EGFR-IN-53 (Compound 7) is a potent inhibitor of EGFR (IC50 = 8.264 μM) that exhibits cytotoxic activity against cancer cell lines [1].</p>Fórmula:C14H13N3O2SForma y color:SolidPeso molecular:287.34Peficitinib hydrobromide
CAS:<p>Peficitinib hydrobromide is used in the treatment of Psoriasis and Rheumatoid Arthritis.</p>Fórmula:C18H23BrN4O2Forma y color:SolidPeso molecular:407.312CAY10717
CAS:<p>CAY10717 inhibits 34/104 kinases at 100 nM, targets EGFR/ABL/B-Raf mutations, kills various cancer cells, and blocks HUVEC growth.</p>Fórmula:C29H25F3N6O3Forma y color:SolidPeso molecular:562.54HP1328
CAS:<p>HP1328: potent FLT3/ITD inhibitor, reduces leukemia, extends survival in mice, belongs to benzoimidazole family.</p>Fórmula:C23H23N3O3Forma y color:SolidPeso molecular:389.45Thi-DPPY
CAS:<p>Thi-DPPY: Potent JAK3/BTK inhibitor (IC50: 1.38/62.4 nM), anti-proliferative, anti-inflammatory, potential in IPF research.</p>Fórmula:C28H28ClN5O4SForma y color:SolidPeso molecular:566.07TG53
CAS:<p>TG53 is a tissue transglutaminase (TG2) and fibronectin (FN) protein-protein interaction inhibitor.</p>Fórmula:C21H22ClN5O2Pureza:98%Forma y color:SolidPeso molecular:411.88FLT3-IN-17
CAS:<p>FLT3-IN-17: FAK inhibitor, IC50 of 12 nM; blocks CYPs, FLT3 mutants; IC50 <0.5 nM for D835Y in cancer studies.</p>Fórmula:C23H24N6O2S2Forma y color:SolidPeso molecular:480.61JG26
CAS:<p>JG26 is a potent inhibitor of ADAM17, which can inhibit ADAM8, ADAM17, ADAM10 and MMP-12, with IC50 values of 12 nM, 1.9 nM, 150 nM and 9.4 nM, respectively,</p>Fórmula:C19H22Br2N4O6SPureza:98.79% - 99.08%Forma y color:SolidPeso molecular:594.27GW837016X
CAS:<p>GW837016X, also known as NEU-391, is a potent inhibitor of protozoan parasite proliferation.</p>Fórmula:C25H20ClFN4OSForma y color:SolidPeso molecular:478.97YLT192
CAS:<p>YLT192 is an orally active and bioavailable VEGFR2 inhibitor. It also has potent antiangiogenic activity and antitumor efficacy.</p>Fórmula:C21H19N3O4Pureza:98%Forma y color:SolidPeso molecular:377.39c-Met-IN-11
CAS:<p>c-Met-IN-11 is a potent inhibitor of c-MET (IC50: 41.4 nM) and VEGFR-2 (IC50: 71.1 nM).</p>Fórmula:C30H20F2N4O3Forma y color:SolidPeso molecular:522.5LS-104
CAS:<p>LS-104 is a JAK2 inhibitor.</p>Fórmula:C19H16N2O3Forma y color:SolidPeso molecular:320.34FGFR-IN-9
<p>FGFR-IN-9: oral FGFR inhibitor, IC50: 17.1 nM (FGFR4 WT), 29.6 (FGFR3), 30.7 (V550L), 46.7 (FGFR2), 64.3 nM (FGFR1).</p>Fórmula:C25H28N6O3SForma y color:SolidPeso molecular:492.59AP 24149
CAS:<p>AP 24149, a potent dual inhibitor targeting Src and Abl, exhibits IC50 values of 9.1 nM for Src and 3.6 nM for Abl, respectively.</p>Fórmula:C23H24N5OPForma y color:SolidPeso molecular:417.44EGFR-IN-28
CAS:<p>EGFR-IN-28 is a potent EGFR inhibitor. EGFR-IN-28 has antitumor activity .</p>Fórmula:C31H39BrN10O3SForma y color:SolidPeso molecular:711.68BLK degrader 1
CAS:<p>BLK degrader 1 is a BLK degrader with anticancer activity for cancer research.</p>Fórmula:C32H25F3N6O2Pureza:99.22% - 99.24%Forma y color:SolidPeso molecular:582.58LRRK2/NUAK1/TYK2-IN-1
CAS:<p>LRRK2/NUAK1/TYK2-IN-1 inhibits LRRK2, TYK2, NUAK1 with IC50 < 10 nM, useful in autoimmune research.</p>Fórmula:C20H11F3N6Forma y color:SolidPeso molecular:392.34Tyrphostin AG 568
CAS:<p>Tyrphostin AG 568 promotes Tyrphostin-induced inhibition of p210bcr-abl tyrosine kinase activity. It also induces K562 to differentiate.</p>Fórmula:C13H9N5O2Pureza:98%Forma y color:SolidPeso molecular:267.24TL02-59 dihydrochloride
CAS:<p>TL02-59 dihydrochloride is an orally active inhibitor of Src-family kinase Fgr (IC50: 0.03 nM).</p>Fórmula:C32H36Cl2F3N5O4Pureza:98%Forma y color:SolidPeso molecular:682.56WB-308
CAS:<p>WB-308 is an EGFR inhibitor that acts by decreasing NSCLC cell proliferation and colony formation and causing G2/M arrest and apoptosis.</p>Fórmula:C19H17FN2OPureza:98%Forma y color:SolidPeso molecular:308.35VEGFR-2-IN-28
CAS:<p>VEGFR-2-IN-28 is a potent inhibitor of VEGFR-2 (IC50: 0.83 μM). VEGFR-2-IN-28 induces apoptosis and exhibits antitumor effects.</p>Fórmula:C26H17N7O7Forma y color:SolidPeso molecular:539.46Momelotinib Mesylate
CAS:<p>Momelotinib Mesylate is an ATP-competitive JAK1/JAK2 inhibitor (IC50: 11 nM/18 nM). It has 10-fold selectivity versus JAK3.</p>Fórmula:C24H26N6O5SPureza:98%Forma y color:SolidPeso molecular:510.57ER 27319 maleate
CAS:<p>Selective inhibitor of Syk kinase</p>Fórmula:C22H24N2O5Pureza:98%Forma y color:SolidPeso molecular:396.44FAK/aurora kinase-IN-1
CAS:<p>FAK/aurora kinase-IN-1, a dual inhibitor of FAK and aurora kinase, has IC50 values of 6.61 nM and 0.91 nM respectively, and demonstrates anticancer effects (WO2018019252A1; compound 11) [1].</p>Fórmula:C23H24ClN7O3Forma y color:SolidPeso molecular:481.93FGFR3-IN-5
CAS:<p>FGFR3-IN-5: potent, selective FGFR3 inhibitor. IC50: 3 nM FGFR3, 44 nM FGFR2, 289 nM FGFR1. For cancer research.</p>Fórmula:C24H24FN7O3Forma y color:SolidPeso molecular:477.49S116836
CAS:<p>S116836 is a tyrosine kinase inhibitor.</p>Fórmula:C27H21F3N6OPureza:98%Forma y color:SolidPeso molecular:502.49DS21360717
CAS:<p>DS21360717 is an effective oral tyrosine kinase inhibitor with anticancer activity and IC50 of 0.49 nM.</p>Fórmula:C21H23N7OPureza:98%Forma y color:SolidPeso molecular:389.45Multi-kinase-IN-2
CAS:<p>Orally active Multi-kinase-IN-2 blocks angiokinases including VEGFR, PDGFR, FGFR, and more, reducing AKT/ERK phosphorylation and promoting apoptosis.</p>Fórmula:C34H35N5O3Forma y color:SolidPeso molecular:561.67FAK inhibitor 5
CAS:<p>FAK inhibitor 5 is a novel allosteric FAK inhibitor, with IC50 values in the low micromolar range.</p>Fórmula:C20H21N3O2SPureza:98%Forma y color:SolidPeso molecular:367.46SB-220025 trihydrochloride
CAS:<p>SB-220025 trihydrochloride is an effective and specific human p38 mitogen-activated protein kinase inhibitor.</p>Fórmula:C18H22Cl3FN6Pureza:98%Forma y color:SolidPeso molecular:447.77PDGFRα/FLT3-ITD-IN-2
CAS:<p>PDGFRα/FLT3-ITD-IN-2 is a potent inhibitor of PDGFRα (IC50>20 μM) and FLT3 (IC50: 0.004 μM).</p>Fórmula:C28H41N9OForma y color:SolidPeso molecular:519.68PD173952
CAS:<p>PD173952 is a Src kinase and Myt1 inhibitor with antitumor activity, inhibits Lyn, Abl and Csk, and induces Bcr-Abl-dependent hematopoietic cell apoptosis.</p>Fórmula:C24H21Cl2N5O2Pureza:99.5%Forma y color:SolidPeso molecular:482.36YH-306
CAS:<p>YH-306 (TRV055 acetate ) is a modulator of the FAK signaling pathway that acts by suppressing colorectal tumor growth and metastasis.</p>Fórmula:C19H18N2O2Pureza:98.06%Forma y color:SolidPeso molecular:306.36
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