RAAS
Los inhibidores del sistema renina-angiotensina-aldosterona (RAAS) son compuestos que se dirigen a la vía del RAAS, conocida principalmente por su papel en la regulación de la presión arterial y el equilibrio de líquidos, pero que también influye en la angiogénesis. La vía del RAAS puede contribuir al desarrollo de nuevos vasos sanguíneos en los tumores, apoyando así su crecimiento. Inhibir los componentes del RAAS puede, por lo tanto, tener efectos antiangiogénicos, lo que convierte a estos inhibidores en herramientas valiosas en el tratamiento de ciertos cánceres y trastornos vasculares. En CymitQuimica, ofrecemos una gama de inhibidores de alta calidad del RAAS para apoyar su investigación en biología cardiovascular, oncología y angiogénesis.
Se han encontrado 97 productos para "RAAS".
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Losartan potassium
CAS:Losartan potassium (DuP-753 potassium) , an Angiotensin II Receptor Blocker, selectively and competitively blocks the binding of angiotensin II to theFórmula:C22H22ClN6OPureza:99.85% - >99.99%Forma y color:White SolidPeso molecular:421.903Valsartan Methyl Ester
CAS:Valsartan Methyl Ester is a potent angiotensin II receptor antagonist, IC50= 0.06uM.Fórmula:C25H31N5O3Pureza:99.54%Forma y color:White SolidPeso molecular:449.5453Pomisartan 2HCl
Pomisartan 2HCl (BIBR363 2HCL) is a small molecule AT1R antagonist used to study heart failure and hypertension.Fórmula:C31H32Cl2N4O2Pureza:99.88%Forma y color:SoildPeso molecular:563.52Olmesartan Medoxomil
CAS:Olmesartan Medoxomil (Benicar) is an angiotensin II type 1 receptor blocker that is used to manage hypertension.Fórmula:C30H32N6O6Pureza:99.89% - 99.9%Forma y color:SolidPeso molecular:572.6117Zansecimab
CAS:Zansecimab (LY-3127804) is a monoclonal antibody targeting angiopoietin 2 (Ang 2) for the study of cardiovascular and immune diseases.Pureza:97.8% (SDS-PAGE); 99.7% (SEC-HPLC) - 97.8% (SDS-PAGE); 99.7% (SEC-HPLC)Forma y color:Transparent LiquidPeso molecular:145.23 kDa (Predicted)Losartan
CAS:Losartan (DuP-753) is an angiotensin II receptor antagonist.Fórmula:C22H23ClN6OPureza:99.48% - >99.99%Forma y color:SolidPeso molecular:422.911TRV055 acetate
TRV055 acetate is a ligand of angiotensin II type 1 receptor and stimulates cellular Gq-mediated signaling.Fórmula:C44H61N9O11Pureza:99.94%Forma y color:SolidPeso molecular:892.01Angiotensin II (1-4), human
CAS:Angiotensin II constricts blood vessels and boosts blood pressure by escalating norepinephrine release.Fórmula:C24H37N7O8Pureza:98%Forma y color:SolidPeso molecular:551.59Saralasin
CAS:Saralasin: angiotensin II antagonist (Ki=0.32 nM) with partial agonist activity, for renovascular & renin-dependent hypertension research.Fórmula:C42H65N13O10Pureza:98%Forma y color:SolidPeso molecular:912.06[Sar1, Ile8]-Angiotensin II
CAS:[Sar1, Ile8]-Angiotensin II(3TFA) is a peptide that has multiple effects on vascular smooth muscle.Fórmula:C46H73N13O10Pureza:98%Forma y color:SolidPeso molecular:968.15Angiotensin II (5-8), human
CAS:Angiotensin II (5-8) is an endogenous C-terminal fragment of the peptide vasoconstrictor angiotensin IIFórmula:C26H36N6O5Pureza:98%Forma y color:SolidPeso molecular:512.6012Angiotensin II (1-4), human TFA
Angiotensin II is a potent direct vasoconstrictor, causing arteries and veins to constrict, so leading to an increase in blood pressure.Fórmula:C26H38F3N7O10Pureza:98%Forma y color:SolidPeso molecular:665.62Angiotensin amide
CAS:Angiotensin amide, an octapeptide amide, can be used to increase blood pressure by vasoconstriction.Fórmula:C49H70N14O11Pureza:98%Forma y color:SolidPeso molecular:1031.17Pemivibart
Pemivibart is an anti-SARS-CoV-2 RBD mAb that blocks ACE2 binding for immunocompromised patients.Peso molecular:~150 kDaAliskiren-D6 hydrochloride
CAS:Aliskiren (CGP 60536) D6 Hydrochloride is a deuterium-labeled Aliskiren. Aliskiren hemifumarate is a direct and orally active renin inhibitor (IC50: 1.5 nM).Fórmula:C30H54ClN3O6Pureza:98%Forma y color:SolidPeso molecular:594.26[Sar1, Ile8]-Angiotensin II acetate
'[Sar1, Ile8]-Angiotensin II acetate triggers oxidases and prompts superoxide in muscles; has varied vascular impacts.Fórmula:C48H77N13O12Pureza:99.36%Forma y color:SolidPeso molecular:1028.2Handle region peptide, rat
CAS:Rat handle region peptide acts as prorenin receptor blocker, curbs diabetic kidney disease, and reduces eye inflammation.Fórmula:C54H101N15O12SPureza:98%Forma y color:SolidPeso molecular:1184.54TRV120055
CAS:TRV120055 is a Gq-biased agonist with 10x more efficacy on AT1R-Gq than AT1R-βarr2.Fórmula:C34H54N12O7Peso molecular:742.8688Evazarsen sodium
CAS:Evazarsen sodium, an angiotensinogen synthesis inhibitor, possesses antihypertensive properties [1].Fórmula:C296H414N86O146P20S19Na20Forma y color:SolidPeso molecular:9201.6Azilsartan Medoxomil Potassium
CAS:Azilsartan Medoxomil Potassium (TAK-491 Potassium) is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults with essential hypertension.Fórmula:C30H23N4O8·KPureza:99.99%Forma y color:SolidPeso molecular:606.62
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